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The map label for this gene is pepN [H]

Identifier: 77458427

GI number: 77458427

Start: 2482665

End: 2485322

Strand: Direct

Name: pepN [H]

Synonym: Pfl01_2200

Alternate gene names: 77458427

Gene position: 2482665-2485322 (Clockwise)

Preceding gene: 77458426

Following gene: 77458429

Centisome position: 38.56

GC content: 61.66

Gene sequence:

>2658_bases
ATGCGCACCGAACAACCGAAGATGATTTACCTGAAGGACTATCAGGCGCCCGAGTACCTGATCGATGAAACACACCTGAC
CTTCGAGTTGTTCGAGGACCACAGTCTGGTCCACGCGCAACTGGTGATGCGCCGCAACCCGGCCCGTGGCCCGGGCCTGC
CGCCGCTGGTGCTCGATGGTCAGCAGCTGGAACTGCTCTCGGTGACCCTGGCCGACCAGGAACTGAGCGCCGACGATTAC
CAGCTGACCGAGAACCACCTGACCCTGCAACCGGCCAGCGAAACCTTCACGGTCGACACCAGCGTCAGGATCCATCCGGA
AACCAACACCGCACTGGAAGGCCTGTACAAGTCCGGCACGATGTTCTGCACCCAGTGCGAGGCTGAAGGTTTCCGCAAGA
TCACCTATTACCTCGACCGCCCGGACGTGATGAGCAAGTTCACCACCACCGTGGTCGCCGAGCAGCACAGCTATCCGGTG
TTGCTGTCCAACGGCAACCCGATCGCCAGCGGCCCTGGCGAAGATGGCCGGCACTGGGCGACCTGGGAAGACCCGTTCAT
GAAACCGGCGTACCTGTTCGCGCTGGTGGCCGGGGACTTGTGGTGCGTTGAAGACAGCTTCACCACCATGACCAACCGCA
ACGTGGCGCTGCGCATCTATGTCGAGCCGGAAAACATCGACAAGTGTCAGCACGCCATGAACAGCCTGAAGAAGTCGATG
CGCTGGGACGAAGAGGTCTACGGTCGCGAGTACGATCTGGACATCTTCATGATCGTCGCCGTGAACGACTTCAACATGGG
CGCCATGGAGAACAAGGGCCTCAACATCTTCAACTCCAGCGCCGTGCTGGCCCGCGCCGAAACCGCCACCGACGCCGCAC
ACCAGCGGGTCGAGGCGATCGTCGCCCACGAATACTTCCACAACTGGTCGGGCAACCGCGTAACCTGCCGCGACTGGTTC
CAGCTGTCGCTCAAGGAAGGCTTCACGGTGTTCCGCGATGCCGGTTTTTCCTCTGACATGAACTCGGCCACGGTCAAGCG
CATTCAGGACGTGGCGTACCTGCGTACCCACCAGTTCGCCGAAGACGCAGGTCCCATGGCCCACGCCGTGCGCCCGGACA
GCTTTATCGAGATTTCCAACTTCTACACCCTGACCGTGTACGAAAAGGGCTCGGAAGTGGTCGGCATGATCCACACCCTG
CTGGGCGCCGAAGGCTTCCGCAAGGGCAGCGATCTGTACTTTGAACGCCACGACGGCCAGGCCGTGACCTGCGATGACTT
CATCAAGGCCATGGAAGATGCCAACGGCGTCGACCTGACCCAGTTCAAGCGCTGGTACAGCCAGGCCGGTACACCGCGTC
TGGCGGTGAGCGAGTCTTACGACGCCGCCGCGAAAACCTACAGCCTGACCTTCCGCCAGAGCTGCCCGGAAACCCCGGAC
AAGGTTGAAAAGCTGCCGTTCGTGATTCCGGTGGAACTGGGCCTGCTCGACAGCCAGGGCAACGAGATCGCCCTGCGTCT
GGCCGGCGAAGCCTCGGCTCAAGGCACCTCCCGGGTGATTTCGGTGACCGAAGCCGAGCAGACCTTCACCTTCGTCGACA
TCGCCGAACAACCGCTGCCGTCCTTGCTGCGTGGCTTCTCGGCGCCGGTGAAACTGAGCTTTCCGTACAACCGCGATCAG
TTGATGTTCCTGATGCAGCACGACACCGACGGTTTCAACCGTTGGGATGCCGGCCAGCAACTGTCGGTGCAGGTGCTGCA
AGAGTTGATCGGCCAGCAGCAAAAGGGCGAAAGCCTGGTGCTCGACCCGCGTCTGGTTTCCGCTTTGCGCACGGTGCTGT
CGGACGAGACGCTGGATCAGGCGATGGTCGCGGAAATGCTCTCGCTGCCAAGCGAAGCGTACCTGACCGAAATCAGTGAA
ATCGCCGACGTGGACGCGATCCACACCGCCCGCGAATTTGCCCGTCAGCAACTGGCGGACAACCTGTTCGAACCACTGTG
GCTGCGTTATCAGGCCAACCGCGACCTGTCGAAGCAAACCCCGTACGTGGCCGAGGCCGAGCACTTCGCCCGTCGCGCGC
TGCAAAACATCGCGCTGTCGTACCTGATGCTCAGCGGCAAGCCGGAAGTCCTGGCGGCGACACTGGAACAGTTCGACAGC
TGCGACAACATGACCGAACGCCTGACCGCGCTGGCGGTGCTGGTCAACTCGCCGTTCGACGAGCAGAAAGCCAAAGCCCT
GGCCAGTTTCGCCGAGCACTTCAAGGACAATCCGCTGGTCATGGATCAGTGGTTCAGCGTGCAGGCCGGCAGCACCTTGC
CGGGCGGTCTGGAGCGCGTGAAAGCGCTGATGCAGCACCCGGCGTTCAACATCAAGAACCCGAACAAGGTGCGTGCGCTG
GTCGGTGCGTTTGCCGGGCAGAACCTGATCAACTTCCACGCGGCGGATGGCTCGGGCTATCGCTTCCTCGCGGATCTGGT
GATCGAACTGAACGGCTTCAACCCGCAGATCGCCTCTCGCCAATTGGCGCCGCTGACGCGCTGGCGTAAATATGACAGCG
CTCGTCAGGCGCTGATGAAGGCGGAGCTGGAGCGGATTCTGGCTTCGGGGCAGCTGTCCAGCGATGTGTATGAAGTGGTC
AGCAAAAGCCTTGCCTGA

Upstream 100 bases:

>100_bases
CTGGGGATCAAGGGCCAGTACCTGATCTTCGACACCGGCGTGATCAACATTCGCAAGTACACGGCCTATCAGCTCGCCGT
GCATCAATAAGGACTTCAGC

Downstream 100 bases:

>100_bases
AGTCTTTTCGGGGCAATAAAAAACGCCGCTCAATGAGCGGCGTTTTTGTGGGGCGATGAAAAGCCCTTATTGGCGCAGAT
CAAACCGATCCAGATCCATC

Product: aminopeptidase N

Products: NA

Alternate protein names: Alpha-aminoacylpeptide hydrolase [H]

Number of amino acids: Translated: 885; Mature: 885

Protein sequence:

>885_residues
MRTEQPKMIYLKDYQAPEYLIDETHLTFELFEDHSLVHAQLVMRRNPARGPGLPPLVLDGQQLELLSVTLADQELSADDY
QLTENHLTLQPASETFTVDTSVRIHPETNTALEGLYKSGTMFCTQCEAEGFRKITYYLDRPDVMSKFTTTVVAEQHSYPV
LLSNGNPIASGPGEDGRHWATWEDPFMKPAYLFALVAGDLWCVEDSFTTMTNRNVALRIYVEPENIDKCQHAMNSLKKSM
RWDEEVYGREYDLDIFMIVAVNDFNMGAMENKGLNIFNSSAVLARAETATDAAHQRVEAIVAHEYFHNWSGNRVTCRDWF
QLSLKEGFTVFRDAGFSSDMNSATVKRIQDVAYLRTHQFAEDAGPMAHAVRPDSFIEISNFYTLTVYEKGSEVVGMIHTL
LGAEGFRKGSDLYFERHDGQAVTCDDFIKAMEDANGVDLTQFKRWYSQAGTPRLAVSESYDAAAKTYSLTFRQSCPETPD
KVEKLPFVIPVELGLLDSQGNEIALRLAGEASAQGTSRVISVTEAEQTFTFVDIAEQPLPSLLRGFSAPVKLSFPYNRDQ
LMFLMQHDTDGFNRWDAGQQLSVQVLQELIGQQQKGESLVLDPRLVSALRTVLSDETLDQAMVAEMLSLPSEAYLTEISE
IADVDAIHTAREFARQQLADNLFEPLWLRYQANRDLSKQTPYVAEAEHFARRALQNIALSYLMLSGKPEVLAATLEQFDS
CDNMTERLTALAVLVNSPFDEQKAKALASFAEHFKDNPLVMDQWFSVQAGSTLPGGLERVKALMQHPAFNIKNPNKVRAL
VGAFAGQNLINFHAADGSGYRFLADLVIELNGFNPQIASRQLAPLTRWRKYDSARQALMKAELERILASGQLSSDVYEVV
SKSLA

Sequences:

>Translated_885_residues
MRTEQPKMIYLKDYQAPEYLIDETHLTFELFEDHSLVHAQLVMRRNPARGPGLPPLVLDGQQLELLSVTLADQELSADDY
QLTENHLTLQPASETFTVDTSVRIHPETNTALEGLYKSGTMFCTQCEAEGFRKITYYLDRPDVMSKFTTTVVAEQHSYPV
LLSNGNPIASGPGEDGRHWATWEDPFMKPAYLFALVAGDLWCVEDSFTTMTNRNVALRIYVEPENIDKCQHAMNSLKKSM
RWDEEVYGREYDLDIFMIVAVNDFNMGAMENKGLNIFNSSAVLARAETATDAAHQRVEAIVAHEYFHNWSGNRVTCRDWF
QLSLKEGFTVFRDAGFSSDMNSATVKRIQDVAYLRTHQFAEDAGPMAHAVRPDSFIEISNFYTLTVYEKGSEVVGMIHTL
LGAEGFRKGSDLYFERHDGQAVTCDDFIKAMEDANGVDLTQFKRWYSQAGTPRLAVSESYDAAAKTYSLTFRQSCPETPD
KVEKLPFVIPVELGLLDSQGNEIALRLAGEASAQGTSRVISVTEAEQTFTFVDIAEQPLPSLLRGFSAPVKLSFPYNRDQ
LMFLMQHDTDGFNRWDAGQQLSVQVLQELIGQQQKGESLVLDPRLVSALRTVLSDETLDQAMVAEMLSLPSEAYLTEISE
IADVDAIHTAREFARQQLADNLFEPLWLRYQANRDLSKQTPYVAEAEHFARRALQNIALSYLMLSGKPEVLAATLEQFDS
CDNMTERLTALAVLVNSPFDEQKAKALASFAEHFKDNPLVMDQWFSVQAGSTLPGGLERVKALMQHPAFNIKNPNKVRAL
VGAFAGQNLINFHAADGSGYRFLADLVIELNGFNPQIASRQLAPLTRWRKYDSARQALMKAELERILASGQLSSDVYEVV
SKSLA
>Mature_885_residues
MRTEQPKMIYLKDYQAPEYLIDETHLTFELFEDHSLVHAQLVMRRNPARGPGLPPLVLDGQQLELLSVTLADQELSADDY
QLTENHLTLQPASETFTVDTSVRIHPETNTALEGLYKSGTMFCTQCEAEGFRKITYYLDRPDVMSKFTTTVVAEQHSYPV
LLSNGNPIASGPGEDGRHWATWEDPFMKPAYLFALVAGDLWCVEDSFTTMTNRNVALRIYVEPENIDKCQHAMNSLKKSM
RWDEEVYGREYDLDIFMIVAVNDFNMGAMENKGLNIFNSSAVLARAETATDAAHQRVEAIVAHEYFHNWSGNRVTCRDWF
QLSLKEGFTVFRDAGFSSDMNSATVKRIQDVAYLRTHQFAEDAGPMAHAVRPDSFIEISNFYTLTVYEKGSEVVGMIHTL
LGAEGFRKGSDLYFERHDGQAVTCDDFIKAMEDANGVDLTQFKRWYSQAGTPRLAVSESYDAAAKTYSLTFRQSCPETPD
KVEKLPFVIPVELGLLDSQGNEIALRLAGEASAQGTSRVISVTEAEQTFTFVDIAEQPLPSLLRGFSAPVKLSFPYNRDQ
LMFLMQHDTDGFNRWDAGQQLSVQVLQELIGQQQKGESLVLDPRLVSALRTVLSDETLDQAMVAEMLSLPSEAYLTEISE
IADVDAIHTAREFARQQLADNLFEPLWLRYQANRDLSKQTPYVAEAEHFARRALQNIALSYLMLSGKPEVLAATLEQFDS
CDNMTERLTALAVLVNSPFDEQKAKALASFAEHFKDNPLVMDQWFSVQAGSTLPGGLERVKALMQHPAFNIKNPNKVRAL
VGAFAGQNLINFHAADGSGYRFLADLVIELNGFNPQIASRQLAPLTRWRKYDSARQALMKAELERILASGQLSSDVYEVV
SKSLA

Specific function: Aminopeptidase N is involved in the degradation of intracellular peptides generated by protein breakdown during normal growth as well as in response to nutrient starvation [H]

COG id: COG0308

COG function: function code E; Aminopeptidase N

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M1 family [H]

Homologues:

Organism=Homo sapiens, GI158937236, Length=469, Percent_Identity=24.3070362473348, Blast_Score=124, Evalue=5e-28,
Organism=Homo sapiens, GI132814467, Length=400, Percent_Identity=27, Blast_Score=121, Evalue=3e-27,
Organism=Homo sapiens, GI61742777, Length=341, Percent_Identity=25.8064516129032, Blast_Score=105, Evalue=2e-22,
Organism=Homo sapiens, GI61742775, Length=341, Percent_Identity=25.8064516129032, Blast_Score=105, Evalue=3e-22,
Organism=Homo sapiens, GI310123622, Length=391, Percent_Identity=25.0639386189258, Blast_Score=103, Evalue=7e-22,
Organism=Homo sapiens, GI310133497, Length=391, Percent_Identity=25.0639386189258, Blast_Score=101, Evalue=3e-21,
Organism=Homo sapiens, GI94818891, Length=452, Percent_Identity=24.3362831858407, Blast_Score=100, Evalue=1e-20,
Organism=Homo sapiens, GI94818901, Length=452, Percent_Identity=24.3362831858407, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI194306629, Length=405, Percent_Identity=23.4567901234568, Blast_Score=95, Evalue=2e-19,
Organism=Homo sapiens, GI11641261, Length=405, Percent_Identity=23.4567901234568, Blast_Score=95, Evalue=2e-19,
Organism=Homo sapiens, GI157266300, Length=409, Percent_Identity=24.9388753056235, Blast_Score=85, Evalue=3e-16,
Organism=Homo sapiens, GI194239713, Length=358, Percent_Identity=24.3016759776536, Blast_Score=82, Evalue=3e-15,
Organism=Homo sapiens, GI7019561, Length=388, Percent_Identity=23.9690721649485, Blast_Score=74, Evalue=5e-13,
Organism=Homo sapiens, GI4505029, Length=455, Percent_Identity=22.4175824175824, Blast_Score=74, Evalue=9e-13,
Organism=Homo sapiens, GI40316915, Length=285, Percent_Identity=27.3684210526316, Blast_Score=70, Evalue=1e-11,
Organism=Escherichia coli, GI1787163, Length=883, Percent_Identity=49.8301245753114, Blast_Score=856, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71989071, Length=428, Percent_Identity=27.1028037383178, Blast_Score=129, Evalue=7e-30,
Organism=Caenorhabditis elegans, GI71989076, Length=468, Percent_Identity=26.9230769230769, Blast_Score=129, Evalue=7e-30,
Organism=Caenorhabditis elegans, GI17569225, Length=446, Percent_Identity=27.5784753363229, Blast_Score=120, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI17569221, Length=371, Percent_Identity=28.3018867924528, Blast_Score=112, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI115533276, Length=372, Percent_Identity=25.5376344086022, Blast_Score=105, Evalue=9e-23,
Organism=Caenorhabditis elegans, GI115533278, Length=372, Percent_Identity=25.5376344086022, Blast_Score=105, Evalue=9e-23,
Organism=Caenorhabditis elegans, GI133903840, Length=375, Percent_Identity=24, Blast_Score=97, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI193206928, Length=396, Percent_Identity=25, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI193206926, Length=396, Percent_Identity=24.4949494949495, Blast_Score=94, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17544504, Length=438, Percent_Identity=23.972602739726, Blast_Score=86, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17565628, Length=333, Percent_Identity=26.7267267267267, Blast_Score=85, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71984353, Length=357, Percent_Identity=24.0896358543417, Blast_Score=79, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI71984339, Length=357, Percent_Identity=24.0896358543417, Blast_Score=79, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI71990873, Length=325, Percent_Identity=26.4615384615385, Blast_Score=70, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6321837, Length=407, Percent_Identity=28.5012285012285, Blast_Score=122, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI9755335, Length=362, Percent_Identity=28.7292817679558, Blast_Score=117, Evalue=1e-26,
Organism=Saccharomyces cerevisiae, GI6324283, Length=424, Percent_Identity=24.0566037735849, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24646516, Length=459, Percent_Identity=27.2331154684096, Blast_Score=144, Evalue=4e-34,
Organism=Drosophila melanogaster, GI24646518, Length=459, Percent_Identity=27.2331154684096, Blast_Score=144, Evalue=4e-34,
Organism=Drosophila melanogaster, GI24646514, Length=456, Percent_Identity=27.1929824561404, Blast_Score=141, Evalue=2e-33,
Organism=Drosophila melanogaster, GI24651025, Length=452, Percent_Identity=27.212389380531, Blast_Score=125, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24651023, Length=452, Percent_Identity=27.212389380531, Blast_Score=125, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24651021, Length=452, Percent_Identity=27.212389380531, Blast_Score=125, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24655252, Length=485, Percent_Identity=24.3298969072165, Blast_Score=116, Evalue=8e-26,
Organism=Drosophila melanogaster, GI24655257, Length=485, Percent_Identity=24.3298969072165, Blast_Score=116, Evalue=8e-26,
Organism=Drosophila melanogaster, GI24655274, Length=485, Percent_Identity=24.3298969072165, Blast_Score=115, Evalue=9e-26,
Organism=Drosophila melanogaster, GI24655260, Length=485, Percent_Identity=24.3298969072165, Blast_Score=115, Evalue=9e-26,
Organism=Drosophila melanogaster, GI24655265, Length=485, Percent_Identity=24.3298969072165, Blast_Score=115, Evalue=9e-26,
Organism=Drosophila melanogaster, GI24655268, Length=485, Percent_Identity=24.3298969072165, Blast_Score=115, Evalue=9e-26,
Organism=Drosophila melanogaster, GI24651016, Length=398, Percent_Identity=27.8894472361809, Blast_Score=114, Evalue=2e-25,
Organism=Drosophila melanogaster, GI21358341, Length=362, Percent_Identity=27.9005524861878, Blast_Score=106, Evalue=7e-23,
Organism=Drosophila melanogaster, GI24646510, Length=395, Percent_Identity=26.5822784810127, Blast_Score=104, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24646512, Length=395, Percent_Identity=26.5822784810127, Blast_Score=104, Evalue=3e-22,
Organism=Drosophila melanogaster, GI161078673, Length=407, Percent_Identity=25.7985257985258, Blast_Score=100, Evalue=7e-21,
Organism=Drosophila melanogaster, GI28571901, Length=407, Percent_Identity=25.7985257985258, Blast_Score=100, Evalue=7e-21,
Organism=Drosophila melanogaster, GI221379089, Length=339, Percent_Identity=26.5486725663717, Blast_Score=96, Evalue=2e-19,
Organism=Drosophila melanogaster, GI45550850, Length=371, Percent_Identity=25.8760107816712, Blast_Score=92, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24650973, Length=371, Percent_Identity=25.8760107816712, Blast_Score=91, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24648786, Length=222, Percent_Identity=30.1801801801802, Blast_Score=85, Evalue=2e-16,
Organism=Drosophila melanogaster, GI221330574, Length=351, Percent_Identity=25.0712250712251, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24648790, Length=403, Percent_Identity=23.0769230769231, Blast_Score=74, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24648784, Length=303, Percent_Identity=25.0825082508251, Blast_Score=71, Evalue=4e-12,
Organism=Drosophila melanogaster, GI281362221, Length=302, Percent_Identity=25.1655629139073, Blast_Score=71, Evalue=4e-12,
Organism=Drosophila melanogaster, GI28571792, Length=231, Percent_Identity=28.5714285714286, Blast_Score=69, Evalue=1e-11,
Organism=Drosophila melanogaster, GI45550350, Length=376, Percent_Identity=25, Blast_Score=68, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24585062, Length=376, Percent_Identity=25, Blast_Score=68, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24585064, Length=376, Percent_Identity=25, Blast_Score=68, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24585066, Length=376, Percent_Identity=25, Blast_Score=68, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001930
- InterPro:   IPR014782
- InterPro:   IPR012779 [H]

Pfam domain/function: PF01433 Peptidase_M1 [H]

EC number: =3.4.11.2 [H]

Molecular weight: Translated: 99311; Mature: 99311

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTEQPKMIYLKDYQAPEYLIDETHLTFELFEDHSLVHAQLVMRRNPARGPGLPPLVLDG
CCCCCCCEEEEECCCCCCHHHCCCCEEEEEECCCCHHHHHHHHHCCCCCCCCCCCEEECC
QQLELLSVTLADQELSADDYQLTENHLTLQPASETFTVDTSVRIHPETNTALEGLYKSGT
CCEEEEEEEEECCCCCCCCCEEECCEEEEEECCCEEEEECEEEECCCCCHHHHHHHCCCC
MFCTQCEAEGFRKITYYLDRPDVMSKFTTTVVAEQHSYPVLLSNGNPIASGPGEDGRHWA
EEEEECCCCCCEEEEEEECCCHHHHHHHHHHEEECCCCCEEEECCCCCCCCCCCCCCCCC
TWEDPFMKPAYLFALVAGDLWCVEDSFTTMTNRNVALRIYVEPENIDKCQHAMNSLKKSM
CCCCCCCCHHHHHHHHHCCEEEEECCCCEECCCCEEEEEEECCCCHHHHHHHHHHHHHHC
RWDEEVYGREYDLDIFMIVAVNDFNMGAMENKGLNIFNSSAVLARAETATDAAHQRVEAI
CCCHHHCCCEECCEEEEEEEEECCCCCCCCCCCCEEECCCEEEEECHHHHHHHHHHHHHH
VAHEYFHNWSGNRVTCRDWFQLSLKEGFTVFRDAGFSSDMNSATVKRIQDVAYLRTHQFA
HHHHHHHCCCCCEEEEHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHH
EDAGPMAHAVRPDSFIEISNFYTLTVYEKGSEVVGMIHTLLGAEGFRKGSDLYFERHDGQ
HHCCCHHCCCCCCCEEEEECEEEEEEECCCCHHHHHHHHHHCCCCCCCCCCCEEEECCCC
AVTCDDFIKAMEDANGVDLTQFKRWYSQAGTPRLAVSESYDAAAKTYSLTFRQSCPETPD
EEEHHHHHHHHHCCCCCCHHHHHHHHHHCCCCEEEECCCCCCHHHEEEEEEHHCCCCCHH
KVEKLPFVIPVELGLLDSQGNEIALRLAGEASAQGTSRVISVTEAEQTFTFVDIAEQPLP
HHHHCCEEEEEEEEEEECCCCEEEEEEECCCCCCCCCEEEEEEEHHHEEEEEEHHHCCHH
SLLRGFSAPVKLSFPYNRDQLMFLMQHDTDGFNRWDAGQQLSVQVLQELIGQQQKGESLV
HHHHCCCCCEEEECCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEE
LDPRLVSALRTVLSDETLDQAMVAEMLSLPSEAYLTEISEIADVDAIHTAREFARQQLAD
ECHHHHHHHHHHHCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NLFEPLWLRYQANRDLSKQTPYVAEAEHFARRALQNIALSYLMLSGKPEVLAATLEQFDS
HHHHHHEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHC
CDNMTERLTALAVLVNSPFDEQKAKALASFAEHFKDNPLVMDQWFSVQAGSTLPGGLERV
CCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCEEEECCEEEECCCCCCCHHHHH
KALMQHPAFNIKNPNKVRALVGAFAGQNLINFHAADGSGYRFLADLVIELNGFNPQIASR
HHHHHCCCCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCHHEEEEHHHEECCCCHHHHCC
QLAPLTRWRKYDSARQALMKAELERILASGQLSSDVYEVVSKSLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MRTEQPKMIYLKDYQAPEYLIDETHLTFELFEDHSLVHAQLVMRRNPARGPGLPPLVLDG
CCCCCCCEEEEECCCCCCHHHCCCCEEEEEECCCCHHHHHHHHHCCCCCCCCCCCEEECC
QQLELLSVTLADQELSADDYQLTENHLTLQPASETFTVDTSVRIHPETNTALEGLYKSGT
CCEEEEEEEEECCCCCCCCCEEECCEEEEEECCCEEEEECEEEECCCCCHHHHHHHCCCC
MFCTQCEAEGFRKITYYLDRPDVMSKFTTTVVAEQHSYPVLLSNGNPIASGPGEDGRHWA
EEEEECCCCCCEEEEEEECCCHHHHHHHHHHEEECCCCCEEEECCCCCCCCCCCCCCCCC
TWEDPFMKPAYLFALVAGDLWCVEDSFTTMTNRNVALRIYVEPENIDKCQHAMNSLKKSM
CCCCCCCCHHHHHHHHHCCEEEEECCCCEECCCCEEEEEEECCCCHHHHHHHHHHHHHHC
RWDEEVYGREYDLDIFMIVAVNDFNMGAMENKGLNIFNSSAVLARAETATDAAHQRVEAI
CCCHHHCCCEECCEEEEEEEEECCCCCCCCCCCCEEECCCEEEEECHHHHHHHHHHHHHH
VAHEYFHNWSGNRVTCRDWFQLSLKEGFTVFRDAGFSSDMNSATVKRIQDVAYLRTHQFA
HHHHHHHCCCCCEEEEHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHH
EDAGPMAHAVRPDSFIEISNFYTLTVYEKGSEVVGMIHTLLGAEGFRKGSDLYFERHDGQ
HHCCCHHCCCCCCCEEEEECEEEEEEECCCCHHHHHHHHHHCCCCCCCCCCCEEEECCCC
AVTCDDFIKAMEDANGVDLTQFKRWYSQAGTPRLAVSESYDAAAKTYSLTFRQSCPETPD
EEEHHHHHHHHHCCCCCCHHHHHHHHHHCCCCEEEECCCCCCHHHEEEEEEHHCCCCCHH
KVEKLPFVIPVELGLLDSQGNEIALRLAGEASAQGTSRVISVTEAEQTFTFVDIAEQPLP
HHHHCCEEEEEEEEEEECCCCEEEEEEECCCCCCCCCEEEEEEEHHHEEEEEEHHHCCHH
SLLRGFSAPVKLSFPYNRDQLMFLMQHDTDGFNRWDAGQQLSVQVLQELIGQQQKGESLV
HHHHCCCCCEEEECCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEE
LDPRLVSALRTVLSDETLDQAMVAEMLSLPSEAYLTEISEIADVDAIHTAREFARQQLAD
ECHHHHHHHHHHHCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NLFEPLWLRYQANRDLSKQTPYVAEAEHFARRALQNIALSYLMLSGKPEVLAATLEQFDS
HHHHHHEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHC
CDNMTERLTALAVLVNSPFDEQKAKALASFAEHFKDNPLVMDQWFSVQAGSTLPGGLERV
CCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCEEEECCEEEECCCCCCCHHHHH
KALMQHPAFNIKNPNKVRALVGAFAGQNLINFHAADGSGYRFLADLVIELNGFNPQIASR
HHHHHCCCCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCHHEEEEHHHEECCCCHHHHCC
QLAPLTRWRKYDSARQALMKAELERILASGQLSSDVYEVVSKSLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2436977; 3549459; 8905232; 9278503; 3018440; 2869947 [H]