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The map label for this gene is adrA [H]

Identifier: 77458403

GI number: 77458403

Start: 2457383

End: 2458348

Strand: Direct

Name: adrA [H]

Synonym: Pfl01_2176

Alternate gene names: 77458403

Gene position: 2457383-2458348 (Clockwise)

Preceding gene: 77458402

Following gene: 77458412

Centisome position: 38.17

GC content: 60.04

Gene sequence:

>966_bases
ATGCTGGTACCCGGCAAACCTGCCAATGAAGCTGTCCGTATTCAAGCGTTGCAGGATCTGAAGCTGCTCGACACCGCACC
GGAGGAGCGCTTCGACCGGCTGACGCGACTGGCCAAGCGTCTGTTCAACGTGCCGATCGCACTGGTCACGCTGGTGGATA
AGGAGCGGCAATGGTTCAAGTCCTGCGTGGGTCTGGACACGACCGAAACGCCACGCTCTGTTTCATTCTGTGCCCATGCG
ATTCTCAGGGACGAGCTTATGCTGGTACCTGACGCCCGAGAGGACGAGCGTTTCCACGACAACCCTTTGGTTACCGGGGA
ACCGAACATCCGGTTCTACGCCGGTTATCCGCTGACCGTACCCAGCGGCAACAAGATGGGCACCTTGTGCCTGATCGACA
CCAAACCCCGCGATCTCGACGAAGAGGAGCGCGCCCTGCTGCGCGATCTGGCGGGCATGGCCGAGCAGGAACTGATGGCC
GTGCAGATGGCGAGCATGGACGAGCTGACGCTGCTGTCCAACCGTCGCGGTTTCAAGATGCTGGCCCAGCATGCGCTCGA
TGCCTGCGCACGGCTGGAAAAACCGGCAACGCTGCTGTTTTTCGACCTCAATGATTTCAAGCAGATCAACGATCTTTATG
GGCACGCCGAGGGCGACAGCGCGCTCAAGACCTTCGCCGATGTGCTGCGCATCGCCTTTCGCGAGAGCGATGTGGTGGGA
CGGCTGGGCGGCGATGAGTTTGTGGCGCTGTTGACCGGCTCAAGCCACGTCGAAACCACGGCGATCATGGCGCGACTCAA
GGAAATCCTCGAAGAACGCAATGCCACGTTGCACCGGGGTTACGCGATTCGCTTCAGCGTCGGCCAGATCGAATACAACC
CGCAGCGCCATGAGTCCGTGGATAAGCTGCTGGCGGATGCGGATGCAGCGATGTATGAGCACAAGCAGGCGTTGAAGCGT
TGTTAG

Upstream 100 bases:

>100_bases
GCCGATGCGGGCGGGCCGTGTCCGGTGGCCGGCGGATGAGAGGTTGAGTCATCGCTGATTCGGGCTAAGCTCAAAGGCAT
CGACGACAAAGGAGTGTGTG

Downstream 100 bases:

>100_bases
TGCGAACCCATCGCCAGCAGGCTGGCTCCCACAGAAAAAGACGATGTTAACGAAATCGCAGGCATGAAAAAGCCCGCCTG
AATAGGCGGGCTTTTTATCG

Product: GAF sensor-containing diguanylate cyclase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 321; Mature: 321

Protein sequence:

>321_residues
MLVPGKPANEAVRIQALQDLKLLDTAPEERFDRLTRLAKRLFNVPIALVTLVDKERQWFKSCVGLDTTETPRSVSFCAHA
ILRDELMLVPDAREDERFHDNPLVTGEPNIRFYAGYPLTVPSGNKMGTLCLIDTKPRDLDEEERALLRDLAGMAEQELMA
VQMASMDELTLLSNRRGFKMLAQHALDACARLEKPATLLFFDLNDFKQINDLYGHAEGDSALKTFADVLRIAFRESDVVG
RLGGDEFVALLTGSSHVETTAIMARLKEILEERNATLHRGYAIRFSVGQIEYNPQRHESVDKLLADADAAMYEHKQALKR
C

Sequences:

>Translated_321_residues
MLVPGKPANEAVRIQALQDLKLLDTAPEERFDRLTRLAKRLFNVPIALVTLVDKERQWFKSCVGLDTTETPRSVSFCAHA
ILRDELMLVPDAREDERFHDNPLVTGEPNIRFYAGYPLTVPSGNKMGTLCLIDTKPRDLDEEERALLRDLAGMAEQELMA
VQMASMDELTLLSNRRGFKMLAQHALDACARLEKPATLLFFDLNDFKQINDLYGHAEGDSALKTFADVLRIAFRESDVVG
RLGGDEFVALLTGSSHVETTAIMARLKEILEERNATLHRGYAIRFSVGQIEYNPQRHESVDKLLADADAAMYEHKQALKR
C
>Mature_321_residues
MLVPGKPANEAVRIQALQDLKLLDTAPEERFDRLTRLAKRLFNVPIALVTLVDKERQWFKSCVGLDTTETPRSVSFCAHA
ILRDELMLVPDAREDERFHDNPLVTGEPNIRFYAGYPLTVPSGNKMGTLCLIDTKPRDLDEEERALLRDLAGMAEQELMA
VQMASMDELTLLSNRRGFKMLAQHALDACARLEKPATLLFFDLNDFKQINDLYGHAEGDSALKTFADVLRIAFRESDVVG
RLGGDEFVALLTGSSHVETTAIMARLKEILEERNATLHRGYAIRFSVGQIEYNPQRHESVDKLLADADAAMYEHKQALKR
C

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GGDEF domain [H]

Homologues:

Organism=Escherichia coli, GI1786584, Length=165, Percent_Identity=35.1515151515151, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI87081977, Length=262, Percent_Identity=29.0076335877863, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI145693134, Length=149, Percent_Identity=33.5570469798658, Blast_Score=81, Evalue=8e-17,
Organism=Escherichia coli, GI1788381, Length=207, Percent_Identity=30.4347826086957, Blast_Score=78, Evalue=9e-16,
Organism=Escherichia coli, GI87082007, Length=156, Percent_Identity=32.0512820512821, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI87081881, Length=208, Percent_Identity=30.7692307692308, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1787816, Length=200, Percent_Identity=29.5, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787541, Length=201, Percent_Identity=28.8557213930348, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI87081974, Length=150, Percent_Identity=31.3333333333333, Blast_Score=65, Evalue=9e-12,
Organism=Escherichia coli, GI1787262, Length=162, Percent_Identity=28.3950617283951, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR007894 [H]

Pfam domain/function: PF00990 GGDEF; PF05230 MASE2 [H]

EC number: NA

Molecular weight: Translated: 36173; Mature: 36173

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVPGKPANEAVRIQALQDLKLLDTAPEERFDRLTRLAKRLFNVPIALVTLVDKERQWFK
CCCCCCCCCCCEEHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
SCVGLDTTETPRSVSFCAHAILRDELMLVPDAREDERFHDNPLVTGEPNIRFYAGYPLTV
HHHCCCCCCCCHHHHHHHHHHHHHCEEECCCCCCCCCCCCCCEEECCCCEEEEECCEEEC
PSGNKMGTLCLIDTKPRDLDEEERALLRDLAGMAEQELMAVQMASMDELTLLSNRRGFKM
CCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCHHHH
LAQHALDACARLEKPATLLFFDLNDFKQINDLYGHAEGDSALKTFADVLRIAFRESDVVG
HHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHC
RLGGDEFVALLTGSSHVETTAIMARLKEILEERNATLHRGYAIRFSVGQIEYNPQRHESV
CCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCEECCEEEEEEECCEEECCHHHHHH
DKLLADADAAMYEHKQALKRC
HHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLVPGKPANEAVRIQALQDLKLLDTAPEERFDRLTRLAKRLFNVPIALVTLVDKERQWFK
CCCCCCCCCCCEEHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
SCVGLDTTETPRSVSFCAHAILRDELMLVPDAREDERFHDNPLVTGEPNIRFYAGYPLTV
HHHCCCCCCCCHHHHHHHHHHHHHCEEECCCCCCCCCCCCCCEEECCCCEEEEECCEEEC
PSGNKMGTLCLIDTKPRDLDEEERALLRDLAGMAEQELMAVQMASMDELTLLSNRRGFKM
CCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCHHHH
LAQHALDACARLEKPATLLFFDLNDFKQINDLYGHAEGDSALKTFADVLRIAFRESDVVG
HHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHC
RLGGDEFVALLTGSSHVETTAIMARLKEILEERNATLHRGYAIRFSVGQIEYNPQRHESV
CCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCEECCEEEEEEECCEEECCHHHHHH
DKLLADADAAMYEHKQALKRC
HHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]