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The map label for this gene is ompR [H]

Identifier: 77458313

GI number: 77458313

Start: 2373245

End: 2373985

Strand: Reverse

Name: ompR [H]

Synonym: Pfl01_2086

Alternate gene names: 77458313

Gene position: 2373985-2373245 (Counterclockwise)

Preceding gene: 77458317

Following gene: 77458312

Centisome position: 36.87

GC content: 62.75

Gene sequence:

>741_bases
ATGGAACATGTCGATCACATCCTGATCGTCGACGACGACCGCGAGATTCGCGAACTGGTCGGCAATTACCTGAAGAAGAA
CGGCCTGCGCACCACGGTGGTTGCCGATGGCCGGCAGATGCGCAGCTTTCTGGAAGCCAACACCGTCGACCTGATCGTGC
TCGACATCATGATGCCCGGCGACGACGGCCTGCTGCTGTGCCGCGAATTGCGCTCGGGCAAACACAAAGCCACGCCGATC
CTGATGCTCACCGCACGCAATGATGAAACCGACCGCATCCTTGGTCTGGAAATGGGCGCTGACGATTACCTGACCAAACC
GTTCGCCGCCCGCGAACTGCTGGCGCGGATCAATGCCGTGCTGCGCCGCACCCGGATGCTGCCGCCGAACCTGGTGGTCA
CCGAAAGCGGTCGGCTGCTGGCGTTCGGTCGCTGGCAGCTCGACACATCGGCTCGGCATCTGCTGGACAAGGACGGCACC
ATGGTCGCGCTGAGTGGCGCGGAATACCGTCTGTTGCGCGTGTTCCTCGACCATCCGCAACGGGTGCTGAGCCGCGATCA
ATTGCTGAATCTGACCCAGGGCCGTGACGCCGATCTGTTCGACCGGTCCATCGATCTGCTGGTCAGTCGCCTGCGCCAGC
GCCTGCTGGATGACGCCCGTGAACCGGCCTACATCAAGACCGTGCGCAGCGAAGGCTATGTGTTCTCGTTGCCGGTCGAA
GTCCTCGGAGCCCCCGCATGA

Upstream 100 bases:

>100_bases
CGTCACAGCGCTGGATACACTGCAATACAAAGGCAGGCAGGCGGCCTCGCGCAGGCTCGATAGACTGCCCGGCAATCCCC
TTTGATTGAGGTTTGGCCCC

Downstream 100 bases:

>100_bases
ATGTCGCCCTGCGCTGGCCGCGCACCCTCGCCTCCCGCTTGTCGCTGATTTTCCTGATCGGGCTGATCCTCGCTCAGGCG
CTGTCGTTCGGCGCGCAATA

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 246; Mature: 246

Protein sequence:

>246_residues
MEHVDHILIVDDDREIRELVGNYLKKNGLRTTVVADGRQMRSFLEANTVDLIVLDIMMPGDDGLLLCRELRSGKHKATPI
LMLTARNDETDRILGLEMGADDYLTKPFAARELLARINAVLRRTRMLPPNLVVTESGRLLAFGRWQLDTSARHLLDKDGT
MVALSGAEYRLLRVFLDHPQRVLSRDQLLNLTQGRDADLFDRSIDLLVSRLRQRLLDDAREPAYIKTVRSEGYVFSLPVE
VLGAPA

Sequences:

>Translated_246_residues
MEHVDHILIVDDDREIRELVGNYLKKNGLRTTVVADGRQMRSFLEANTVDLIVLDIMMPGDDGLLLCRELRSGKHKATPI
LMLTARNDETDRILGLEMGADDYLTKPFAARELLARINAVLRRTRMLPPNLVVTESGRLLAFGRWQLDTSARHLLDKDGT
MVALSGAEYRLLRVFLDHPQRVLSRDQLLNLTQGRDADLFDRSIDLLVSRLRQRLLDDAREPAYIKTVRSEGYVFSLPVE
VLGAPA
>Mature_246_residues
MEHVDHILIVDDDREIRELVGNYLKKNGLRTTVVADGRQMRSFLEANTVDLIVLDIMMPGDDGLLLCRELRSGKHKATPI
LMLTARNDETDRILGLEMGADDYLTKPFAARELLARINAVLRRTRMLPPNLVVTESGRLLAFGRWQLDTSARHLLDKDGT
MVALSGAEYRLLRVFLDHPQRVLSRDQLLNLTQGRDADLFDRSIDLLVSRLRQRLLDDAREPAYIKTVRSEGYVFSLPVE
VLGAPA

Specific function: The N-terminus of this protein is required for the transcriptional expression of both major outer membrane protein genes ompF and ompC; its C-terminal moiety mediates the multimerization of the ompR protein. As a multimer, it turns on the expression of th

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=235, Percent_Identity=45.1063829787234, Blast_Score=199, Evalue=2e-52,
Organism=Escherichia coli, GI1790863, Length=234, Percent_Identity=37.1794871794872, Blast_Score=155, Evalue=2e-39,
Organism=Escherichia coli, GI1786599, Length=231, Percent_Identity=37.6623376623377, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI1788394, Length=236, Percent_Identity=38.135593220339, Blast_Score=148, Evalue=3e-37,
Organism=Escherichia coli, GI1787229, Length=238, Percent_Identity=36.5546218487395, Blast_Score=140, Evalue=7e-35,
Organism=Escherichia coli, GI145693140, Length=237, Percent_Identity=36.7088607594937, Blast_Score=137, Evalue=5e-34,
Organism=Escherichia coli, GI2367329, Length=232, Percent_Identity=37.5, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI1790860, Length=229, Percent_Identity=33.1877729257642, Blast_Score=124, Evalue=8e-30,
Organism=Escherichia coli, GI1786911, Length=234, Percent_Identity=35.8974358974359, Blast_Score=121, Evalue=4e-29,
Organism=Escherichia coli, GI1786784, Length=232, Percent_Identity=36.6379310344828, Blast_Score=120, Evalue=8e-29,
Organism=Escherichia coli, GI87082012, Length=229, Percent_Identity=33.1877729257642, Blast_Score=114, Evalue=5e-27,
Organism=Escherichia coli, GI1787375, Length=233, Percent_Identity=32.1888412017167, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1789402, Length=230, Percent_Identity=33.0434782608696, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1790552, Length=229, Percent_Identity=33.1877729257642, Blast_Score=94, Evalue=9e-21,
Organism=Escherichia coli, GI1790299, Length=109, Percent_Identity=34.8623853211009, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1788191, Length=123, Percent_Identity=33.3333333333333, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1788550, Length=113, Percent_Identity=31.858407079646, Blast_Score=64, Evalue=9e-12,
Organism=Saccharomyces cerevisiae, GI6322000, Length=104, Percent_Identity=37.5, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27884; Mature: 27884

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEHVDHILIVDDDREIRELVGNYLKKNGLRTTVVADGRQMRSFLEANTVDLIVLDIMMPG
CCCCCEEEEEECCHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHCCCEEEEEEEEEECC
DDGLLLCRELRSGKHKATPILMLTARNDETDRILGLEMGADDYLTKPFAARELLARINAV
CCCHHHHHHHHCCCCCCCEEEEEEECCCCCCEEEEEEECCCHHHCCCHHHHHHHHHHHHH
LRRTRMLPPNLVVTESGRLLAFGRWQLDTSARHLLDKDGTMVALSGAEYRLLRVFLDHPQ
HHHHHCCCCCEEEECCCCEEEEEEEEECHHHHHHHCCCCCEEEECCCCHHHHHHHHHCHH
RVLSRDQLLNLTQGRDADLFDRSIDLLVSRLRQRLLDDAREPAYIKTVRSEGYVFSLPVE
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEEEECHH
VLGAPA
HCCCCC
>Mature Secondary Structure
MEHVDHILIVDDDREIRELVGNYLKKNGLRTTVVADGRQMRSFLEANTVDLIVLDIMMPG
CCCCCEEEEEECCHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHCCCEEEEEEEEEECC
DDGLLLCRELRSGKHKATPILMLTARNDETDRILGLEMGADDYLTKPFAARELLARINAV
CCCHHHHHHHHCCCCCCCEEEEEEECCCCCCEEEEEEECCCHHHCCCHHHHHHHHHHHHH
LRRTRMLPPNLVVTESGRLLAFGRWQLDTSARHLLDKDGTMVALSGAEYRLLRVFLDHPQ
HHHHHCCCCCEEEECCCCEEEEEEEEECHHHHHHHCCCCCEEEECCCCHHHHHHHHHCHH
RVLSRDQLLNLTQGRDADLFDRSIDLLVSRLRQRLLDDAREPAYIKTVRSEGYVFSLPVE
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEEEECHH
VLGAPA
HCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]