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The map label for this gene is rtcR [H]

Identifier: 77458171

GI number: 77458171

Start: 2217490

End: 2219091

Strand: Reverse

Name: rtcR [H]

Synonym: Pfl01_1944

Alternate gene names: 77458171

Gene position: 2219091-2217490 (Counterclockwise)

Preceding gene: 77458177

Following gene: 77458157

Centisome position: 34.47

GC content: 62.17

Gene sequence:

>1602_bases
ATGTCCAGCAAGCGCACTGTCGCCATCGGTTTCATCGGAGCCACCCTCGATCGCGTCGGCAAAGGCGCCAACCGCTGGAA
CCATTGGCGGCCTAGCGTCGGCCTGTGCCAGCAACCGGACGTCTTGATCCATCGACTGGAACTGATACACGGCACGGACG
CCCGGGACGCGAGCCTGGCCGAACGCATTCGCGAGGACATCCGTCAGGTGTCGCCGGATACAGAGGTGCGCCTGCACCCG
ATGGCGTTGCGCAACCCCTGGGATTTCGAAGAGGTCTACGGCGCACTCCACGACTTCACCTCCGAATACACCTTCGATAC
CGAGCGTGAGGACTATCTGGTGCACATCACCACGGGGACCCACGTCGCGCAGATCTGCTGGTTCTTGCTGACCGAGGCGC
GCTACCTGCCGGCACGCCTGATCCAGACCTCCCCCGCCCGTCGCAAGAGCGAAGAAGAACCGGCCACCGGCACCCACGCC
CTGATCGACCTTGATCTGTCGCGCTACGACCGGATTGCCTCACGCTTCACCCACAAACGTCTGGAAGGCCTGGAGTTTCT
CAAGTCCGGCATCGCCACTCGCAACACCGCGTTCAACCGTTCCATCGAGCAGATCGAACGCGTGGCCGTGCGCTCCAAAG
CGCCGATGCTGCTGATCGGCCCGACCGGCGCCGGCAAGTCCTTTCTTGCCCGACGCATCTATGAGCTCAAACGCAGTCGC
CATCAAATGCAGGGGCGTTTCGTTGAAGTCAACTGCGCGACCCTGCGTGGCGACTGCGCAATGTCCGCGCTGTTCGGCCA
CGTCAAAGGCGCCTTTACCGGCGCACAAAACGCTCGCGACGGCCTGCTGCGAGCGGCTGACGGCGGCATGTTGTTTCTCG
ACGAGATCGGCGAACTGGGGGCAGATGAACAAGCGATGCTGCTCAAGGCCATCGAAGAGAAGCGCTTCTTCCCGCTGGGC
TCGGACAAGGAAGTCGACAGCGACTTCCTGATCATCGCCGGCACCCACCGCGACCTGCGCAGTCGCGTCGCCGAAGGTCT
GTTCCGGGAAGATCTCTACGCACGGATCAACCTCTGGACGTTCGACCTGCCAGGCTTGGCAGGACGCCGCGAAGACATCG
AACCCAATATCGATTTCGAGCTTGAACGTCACGCACGCGAATACGGCCAACTGGTGCGTTTCAATCTTGAAGCCCGACGG
CGCTACCTGAGTTTCGCCAGCTCACGGGAAGCTGCGTGGCTGGGCAATTTCCGTGAACTCTCGGCCTCGATCACGCGCAT
GGCGACGCTGGCCGACAGCGGGCGAATCGATGCAGCGCAAGTGGAAGAGGAAATTGATCGGCTGAGGTATGCGTGGGGCC
TGGCGCAACCGGCCGGTGCGACAAGTGACCTGCCGGGCGATGCCGAGACGCTGGACCTGTTCGATCGATTGCAATTGAAG
GCGGTTCTGGAGGTTTGCAGACAGGCAGACAGCTTGTCGGATGCCGGCAGACGACTGTTCGGCGTGTCGCGACAGGCGAA
AGCACAGCCCAACGATGCGGACCGATTGAGGAAGTACCTCGGACGGTTCGGCATTGAATGGAGCCAGTTGCGAGAGCGGT
GA

Upstream 100 bases:

>100_bases
GGTTTTGTTCTAACAACGAGCATCCCTGAATTTTCGTCACGACAAATAACGCCCTCGAACACTATCATTGGCTATCGTCA
TTTATCTTTCAGGATAATCC

Downstream 100 bases:

>100_bases
AGCGCGGCCGCAATCGACTAAGCCGTTGAGATAAACTGCGCCACACCGCGATACAAACATCAAGCGAAGGACAGACACGG
ATGAGCTTACTGGAGTTTTT

Product: regulator of RNA terminal phosphate cyclase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 533; Mature: 532

Protein sequence:

>533_residues
MSSKRTVAIGFIGATLDRVGKGANRWNHWRPSVGLCQQPDVLIHRLELIHGTDARDASLAERIREDIRQVSPDTEVRLHP
MALRNPWDFEEVYGALHDFTSEYTFDTEREDYLVHITTGTHVAQICWFLLTEARYLPARLIQTSPARRKSEEEPATGTHA
LIDLDLSRYDRIASRFTHKRLEGLEFLKSGIATRNTAFNRSIEQIERVAVRSKAPMLLIGPTGAGKSFLARRIYELKRSR
HQMQGRFVEVNCATLRGDCAMSALFGHVKGAFTGAQNARDGLLRAADGGMLFLDEIGELGADEQAMLLKAIEEKRFFPLG
SDKEVDSDFLIIAGTHRDLRSRVAEGLFREDLYARINLWTFDLPGLAGRREDIEPNIDFELERHAREYGQLVRFNLEARR
RYLSFASSREAAWLGNFRELSASITRMATLADSGRIDAAQVEEEIDRLRYAWGLAQPAGATSDLPGDAETLDLFDRLQLK
AVLEVCRQADSLSDAGRRLFGVSRQAKAQPNDADRLRKYLGRFGIEWSQLRER

Sequences:

>Translated_533_residues
MSSKRTVAIGFIGATLDRVGKGANRWNHWRPSVGLCQQPDVLIHRLELIHGTDARDASLAERIREDIRQVSPDTEVRLHP
MALRNPWDFEEVYGALHDFTSEYTFDTEREDYLVHITTGTHVAQICWFLLTEARYLPARLIQTSPARRKSEEEPATGTHA
LIDLDLSRYDRIASRFTHKRLEGLEFLKSGIATRNTAFNRSIEQIERVAVRSKAPMLLIGPTGAGKSFLARRIYELKRSR
HQMQGRFVEVNCATLRGDCAMSALFGHVKGAFTGAQNARDGLLRAADGGMLFLDEIGELGADEQAMLLKAIEEKRFFPLG
SDKEVDSDFLIIAGTHRDLRSRVAEGLFREDLYARINLWTFDLPGLAGRREDIEPNIDFELERHAREYGQLVRFNLEARR
RYLSFASSREAAWLGNFRELSASITRMATLADSGRIDAAQVEEEIDRLRYAWGLAQPAGATSDLPGDAETLDLFDRLQLK
AVLEVCRQADSLSDAGRRLFGVSRQAKAQPNDADRLRKYLGRFGIEWSQLRER
>Mature_532_residues
SSKRTVAIGFIGATLDRVGKGANRWNHWRPSVGLCQQPDVLIHRLELIHGTDARDASLAERIREDIRQVSPDTEVRLHPM
ALRNPWDFEEVYGALHDFTSEYTFDTEREDYLVHITTGTHVAQICWFLLTEARYLPARLIQTSPARRKSEEEPATGTHAL
IDLDLSRYDRIASRFTHKRLEGLEFLKSGIATRNTAFNRSIEQIERVAVRSKAPMLLIGPTGAGKSFLARRIYELKRSRH
QMQGRFVEVNCATLRGDCAMSALFGHVKGAFTGAQNARDGLLRAADGGMLFLDEIGELGADEQAMLLKAIEEKRFFPLGS
DKEVDSDFLIIAGTHRDLRSRVAEGLFREDLYARINLWTFDLPGLAGRREDIEPNIDFELERHAREYGQLVRFNLEARRR
YLSFASSREAAWLGNFRELSASITRMATLADSGRIDAAQVEEEIDRLRYAWGLAQPAGATSDLPGDAETLDLFDRLQLKA
VLEVCRQADSLSDAGRRLFGVSRQAKAQPNDADRLRKYLGRFGIEWSQLRER

Specific function: Transcriptional repressor of the rtcAB genes. Interacts with sigma-54 [H]

COG id: COG4650

COG function: function code KT; Sigma54-dependent transcription regulator containing an AAA-type ATPase domain and a DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1789828, Length=530, Percent_Identity=66.7924528301887, Blast_Score=721, Evalue=0.0,
Organism=Escherichia coli, GI1788905, Length=301, Percent_Identity=34.8837209302326, Blast_Score=170, Evalue=2e-43,
Organism=Escherichia coli, GI1789233, Length=246, Percent_Identity=36.9918699186992, Blast_Score=154, Evalue=1e-38,
Organism=Escherichia coli, GI1788550, Length=321, Percent_Identity=35.8255451713396, Blast_Score=151, Evalue=8e-38,
Organism=Escherichia coli, GI1790437, Length=242, Percent_Identity=38.0165289256198, Blast_Score=143, Evalue=2e-35,
Organism=Escherichia coli, GI1789087, Length=241, Percent_Identity=37.7593360995851, Blast_Score=139, Evalue=7e-34,
Organism=Escherichia coli, GI87082117, Length=242, Percent_Identity=36.3636363636364, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI1790299, Length=222, Percent_Identity=39.1891891891892, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI1787583, Length=331, Percent_Identity=31.1178247734139, Blast_Score=125, Evalue=5e-30,
Organism=Escherichia coli, GI87082152, Length=246, Percent_Identity=36.1788617886179, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1786524, Length=240, Percent_Identity=34.5833333333333, Blast_Score=115, Evalue=7e-27,
Organism=Escherichia coli, GI87081872, Length=241, Percent_Identity=33.6099585062241, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI87081858, Length=239, Percent_Identity=30.1255230125523, Blast_Score=95, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR002078
- InterPro:   IPR009715
- InterPro:   IPR017183 [H]

Pfam domain/function: PF06956 RtcR; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 60405; Mature: 60274

Theoretical pI: Translated: 7.18; Mature: 7.18

Prosite motif: PS00676 SIGMA54_INTERACT_2 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSKRTVAIGFIGATLDRVGKGANRWNHWRPSVGLCQQPDVLIHRLELIHGTDARDASLA
CCCCCEEEEEEHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHH
ERIREDIRQVSPDTEVRLHPMALRNPWDFEEVYGALHDFTSEYTFDTEREDYLVHITTGT
HHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCH
HVAQICWFLLTEARYLPARLIQTSPARRKSEEEPATGTHALIDLDLSRYDRIASRFTHKR
HHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCCCCEEEEEECHHHHHHHHHHHHHHH
LEGLEFLKSGIATRNTAFNRSIEQIERVAVRSKAPMLLIGPTGAGKSFLARRIYELKRSR
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHH
HQMQGRFVEVNCATLRGDCAMSALFGHVKGAFTGAQNARDGLLRAADGGMLFLDEIGELG
HHHCCCEEEEEEEECCCHHHHHHHHHHHHHHHCCCCCHHHCCEEECCCCEEEHHHHHCCC
ADEQAMLLKAIEEKRFFPLGSDKEVDSDFLIIAGTHRDLRSRVAEGLFREDLYARINLWT
CCHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHEEEEEE
FDLPGLAGRREDIEPNIDFELERHAREYGQLVRFNLEARRRYLSFASSREAAWLGNFREL
EECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCHHHH
SASITRMATLADSGRIDAAQVEEEIDRLRYAWGLAQPAGATSDLPGDAETLDLFDRLQLK
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHH
AVLEVCRQADSLSDAGRRLFGVSRQAKAQPNDADRLRKYLGRFGIEWSQLRER
HHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHCC
>Mature Secondary Structure 
SSKRTVAIGFIGATLDRVGKGANRWNHWRPSVGLCQQPDVLIHRLELIHGTDARDASLA
CCCCEEEEEEHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHH
ERIREDIRQVSPDTEVRLHPMALRNPWDFEEVYGALHDFTSEYTFDTEREDYLVHITTGT
HHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCH
HVAQICWFLLTEARYLPARLIQTSPARRKSEEEPATGTHALIDLDLSRYDRIASRFTHKR
HHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCCCCEEEEEECHHHHHHHHHHHHHHH
LEGLEFLKSGIATRNTAFNRSIEQIERVAVRSKAPMLLIGPTGAGKSFLARRIYELKRSR
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHH
HQMQGRFVEVNCATLRGDCAMSALFGHVKGAFTGAQNARDGLLRAADGGMLFLDEIGELG
HHHCCCEEEEEEEECCCHHHHHHHHHHHHHHHCCCCCHHHCCEEECCCCEEEHHHHHCCC
ADEQAMLLKAIEEKRFFPLGSDKEVDSDFLIIAGTHRDLRSRVAEGLFREDLYARINLWT
CCHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHEEEEEE
FDLPGLAGRREDIEPNIDFELERHAREYGQLVRFNLEARRRYLSFASSREAAWLGNFREL
EECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCHHHH
SASITRMATLADSGRIDAAQVEEEIDRLRYAWGLAQPAGATSDLPGDAETLDLFDRLQLK
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHH
AVLEVCRQADSLSDAGRRLFGVSRQAKAQPNDADRLRKYLGRFGIEWSQLRER
HHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503; 3045764; 7984428; 7920643; 9738023 [H]