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The map label for this gene is pheS [H]

Identifier: 77458162

GI number: 77458162

Start: 2203686

End: 2204702

Strand: Direct

Name: pheS [H]

Synonym: Pfl01_1935

Alternate gene names: 77458162

Gene position: 2203686-2204702 (Clockwise)

Preceding gene: 77458161

Following gene: 77458163

Centisome position: 34.23

GC content: 57.42

Gene sequence:

>1017_bases
ATGGAAAACCTGGATGCGCTGGTCTCTCAAGCACTAGAGGCTGTGCAAAGCGCTGAAGATATCAATGCCCTGGAGCAAAT
CCGGGTTCAATACCTTGGCAAAAAAGGTGAATTGACTCAGGTGATGAAGACCCTGGGGAATTTGCCGGCAGAAGAGCGTC
CGCAGGTCGGCGCCCTGATCAACGTTGCCAAGGAACGTGTCACAGGCGTTCTCAATGCGCGCATGGCTCTGTTTGAGGAA
GCCGAACTGGCTGCCAAGCTGTCTGCCGAATCCATTGACGTGACCCTGCCGGGCCGTGGTCAGACCTCCGGTGGTCTGCA
TCCGGTAACCCGGACTCTGGAACGTATCGAACAGTTCTTCACTCATATCGGCTACGGCATTGCCGAAGGCCCTGAGGTCG
AAGACGACTATCACAACTTCGAGGCGCTCAACATCCCAGGCCATCACCCGGCCCGGTCGATGCATGACACCTTCTATTTC
AACGCCAACATGTTGCTGCGCACCCATACCTCGCCGGTACAGGTCCGCACCATGGAATCGAAAAAGCCGCCGATCCGCAT
CGTCTGCCCAGGCCGTGTGTATCGCAGCGACTCCGATATCACCCACTCGCCGATGTTCCACCAGGTCGAAGGCCTGCTGG
TCGATCGCGATATCAACTTCGCCGACCTCAAAGGCACGATCGAAGAGTTCCTGCGGGTGTTCTTCGAAAAAGAACTGGCC
GTGCGTTTCCGTCCTTCGTACTTCCCGTTCACCGAGCCTTCCGCCGAAGTCGACATGGAATGCGTGATGTGCAGCGGTAA
AGGCTGCCGCGTCTGCAAACAGACCGGCTGGCTGGAAGTGATGGGCTGCGGCATGGTTCATCCGAACGTATTGCGCATGT
CCGGGATCGATCCGGAAGAGTTCTCGGGCTTTGCCTTCGGCATGGGCGTTGAGCGTCTGGCCATGCTGCGTTACGGCGTG
AACGACTTGCGTCTGTTCTTCGACAACGACTTGCGGTTCCTCGCGCAATTTCGCTAG

Upstream 100 bases:

>100_bases
ACAGTCACCCGGCCTCACCTCTGTGGAGCCAGGTGTTAAACGTCATAAATAGGGGAAGAGCCTTCAAGCTCTTCCCCTAT
TTTGTATCTGGAGTCTGTAC

Downstream 100 bases:

>100_bases
TCGTAACGAATTCTTAGGAGAGCAGGATGAAATTCAGTGAACAATGGCTGCGTGGCTGGGTCAGCCCGCAGGTAGATCGC
GACGCGCTGGTTGCCCGTCT

Product: phenylalanyl-tRNA synthetase subunit alpha

Products: NA

Alternate protein names: Phenylalanine--tRNA ligase alpha chain; PheRS [H]

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MENLDALVSQALEAVQSAEDINALEQIRVQYLGKKGELTQVMKTLGNLPAEERPQVGALINVAKERVTGVLNARMALFEE
AELAAKLSAESIDVTLPGRGQTSGGLHPVTRTLERIEQFFTHIGYGIAEGPEVEDDYHNFEALNIPGHHPARSMHDTFYF
NANMLLRTHTSPVQVRTMESKKPPIRIVCPGRVYRSDSDITHSPMFHQVEGLLVDRDINFADLKGTIEEFLRVFFEKELA
VRFRPSYFPFTEPSAEVDMECVMCSGKGCRVCKQTGWLEVMGCGMVHPNVLRMSGIDPEEFSGFAFGMGVERLAMLRYGV
NDLRLFFDNDLRFLAQFR

Sequences:

>Translated_338_residues
MENLDALVSQALEAVQSAEDINALEQIRVQYLGKKGELTQVMKTLGNLPAEERPQVGALINVAKERVTGVLNARMALFEE
AELAAKLSAESIDVTLPGRGQTSGGLHPVTRTLERIEQFFTHIGYGIAEGPEVEDDYHNFEALNIPGHHPARSMHDTFYF
NANMLLRTHTSPVQVRTMESKKPPIRIVCPGRVYRSDSDITHSPMFHQVEGLLVDRDINFADLKGTIEEFLRVFFEKELA
VRFRPSYFPFTEPSAEVDMECVMCSGKGCRVCKQTGWLEVMGCGMVHPNVLRMSGIDPEEFSGFAFGMGVERLAMLRYGV
NDLRLFFDNDLRFLAQFR
>Mature_338_residues
MENLDALVSQALEAVQSAEDINALEQIRVQYLGKKGELTQVMKTLGNLPAEERPQVGALINVAKERVTGVLNARMALFEE
AELAAKLSAESIDVTLPGRGQTSGGLHPVTRTLERIEQFFTHIGYGIAEGPEVEDDYHNFEALNIPGHHPARSMHDTFYF
NANMLLRTHTSPVQVRTMESKKPPIRIVCPGRVYRSDSDITHSPMFHQVEGLLVDRDINFADLKGTIEEFLRVFFEKELA
VRFRPSYFPFTEPSAEVDMECVMCSGKGCRVCKQTGWLEVMGCGMVHPNVLRMSGIDPEEFSGFAFGMGVERLAMLRYGV
NDLRLFFDNDLRFLAQFR

Specific function: Unknown

COG id: COG0016

COG function: function code J; Phenylalanyl-tRNA synthetase alpha subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha chain type 1 subfamily [H]

Homologues:

Organism=Homo sapiens, GI5729820, Length=289, Percent_Identity=31.1418685121107, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI4758340, Length=270, Percent_Identity=31.1111111111111, Blast_Score=121, Evalue=7e-28,
Organism=Escherichia coli, GI1788007, Length=338, Percent_Identity=63.6094674556213, Blast_Score=454, Evalue=1e-129,
Organism=Caenorhabditis elegans, GI32566635, Length=249, Percent_Identity=33.7349397590361, Blast_Score=122, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI32563657, Length=275, Percent_Identity=29.0909090909091, Blast_Score=120, Evalue=8e-28,
Organism=Caenorhabditis elegans, GI17508957, Length=275, Percent_Identity=29.0909090909091, Blast_Score=120, Evalue=9e-28,
Organism=Saccharomyces cerevisiae, GI6321087, Length=270, Percent_Identity=30, Blast_Score=125, Evalue=9e-30,
Organism=Saccharomyces cerevisiae, GI6325304, Length=279, Percent_Identity=29.3906810035842, Blast_Score=104, Evalue=2e-23,
Organism=Drosophila melanogaster, GI18858079, Length=274, Percent_Identity=30.2919708029197, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI17137424, Length=248, Percent_Identity=30.241935483871, Blast_Score=111, Evalue=9e-25,

Paralogues:

None

Copy number: 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006195
- InterPro:   IPR004529
- InterPro:   IPR004188
- InterPro:   IPR022911
- InterPro:   IPR002319
- InterPro:   IPR010978 [H]

Pfam domain/function: PF02912 Phe_tRNA-synt_N; PF01409 tRNA-synt_2d [H]

EC number: =6.1.1.20 [H]

Molecular weight: Translated: 38021; Mature: 38021

Theoretical pI: Translated: 5.28; Mature: 5.28

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENLDALVSQALEAVQSAEDINALEQIRVQYLGKKGELTQVMKTLGNLPAEERPQVGALI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCHHHHH
NVAKERVTGVLNARMALFEEAELAAKLSAESIDVTLPGRGQTSGGLHPVTRTLERIEQFF
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHH
THIGYGIAEGPEVEDDYHNFEALNIPGHHPARSMHDTFYFNANMLLRTHTSPVQVRTMES
HHHCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCEEEEECEEEEEECCCCEEEEEECC
KKPPIRIVCPGRVYRSDSDITHSPMFHQVEGLLVDRDINFADLKGTIEEFLRVFFEKELA
CCCCEEEECCCCEECCCCCCCCCCHHHHHCCEEEECCCCHHHHHHHHHHHHHHHHHHHHH
VRFRPSYFPFTEPSAEVDMECVMCSGKGCRVCKQTGWLEVMGCGMVHPNVLRMSGIDPEE
EEECCCCCCCCCCCCCCCEEEEEECCCCCHHHHHCCCEEEEECCCCCCCEEEECCCCHHH
FSGFAFGMGVERLAMLRYGVNDLRLFFDNDLRFLAQFR
HCCEEEHHHHHHHHHHHHCCCCEEEEECCCHHHHHCCC
>Mature Secondary Structure
MENLDALVSQALEAVQSAEDINALEQIRVQYLGKKGELTQVMKTLGNLPAEERPQVGALI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCHHHHH
NVAKERVTGVLNARMALFEEAELAAKLSAESIDVTLPGRGQTSGGLHPVTRTLERIEQFF
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHH
THIGYGIAEGPEVEDDYHNFEALNIPGHHPARSMHDTFYFNANMLLRTHTSPVQVRTMES
HHHCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCEEEEECEEEEEECCCCEEEEEECC
KKPPIRIVCPGRVYRSDSDITHSPMFHQVEGLLVDRDINFADLKGTIEEFLRVFFEKELA
CCCCEEEECCCCEECCCCCCCCCCHHHHHCCEEEECCCCHHHHHHHHHHHHHHHHHHHHH
VRFRPSYFPFTEPSAEVDMECVMCSGKGCRVCKQTGWLEVMGCGMVHPNVLRMSGIDPEE
EEECCCCCCCCCCCCCCCEEEEEECCCCCHHHHHCCCEEEEECCCCCCCEEEECCCCHHH
FSGFAFGMGVERLAMLRYGVNDLRLFFDNDLRFLAQFR
HCCEEEHHHHHHHHHHHHCCCCEEEEECCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA