| Definition | Pseudomonas fluorescens Pf0-1 chromosome, complete genome. |
|---|---|
| Accession | NC_007492 |
| Length | 6,438,405 |
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The map label for this gene is fabG [C]
Identifier: 77458131
GI number: 77458131
Start: 2175548
End: 2176315
Strand: Direct
Name: fabG [C]
Synonym: Pfl01_1904
Alternate gene names: 77458131
Gene position: 2175548-2176315 (Clockwise)
Preceding gene: 77458130
Following gene: 77458132
Centisome position: 33.79
GC content: 63.41
Gene sequence:
>768_bases TTGTCTACGCCAAAGATCGGCACCCATGGCCGCGTTGCATTGGTCACGGGTGCCGCGCGCGGGATCGGCTTGGGCATCGC GGCATGGCTGATCAGCGAAGGCTGGCAGGTGGTGCTGACTGACCTGGATCGTGTGCGAGGTTCGAAAGTGGCGAAGGTGC TCGGCGAAAACGCCTGGTTCATTGCCATGGACGTCGCGGACGAAAGTCAGGTGGCGCTCGGTGTCGCTGAGGTGCTGGGG CAATTCGGTCGTCTGGATGCGCTGGTGTGCAACGCTGCCGTGGCCGATCCGCACAACATCACGCTGGAAAGCCTCGATCT GGCTTACTGGAATCGGGTGCTTGCGGTGAACCTCGGTGGGCCGATGTTGCTGGCCAAACACTGCGCGCCGTATCTGCGTG CGCACAACGGGGCGATCGTCAATCTGGCCTCGACCCGTGCGGCGCAGTCAGAACCGGATACCGAAGCCTATGCGGCGAGC AAGGGTGGTTTGCTGGCGCTGACTCACGCGCTGGCGATCAGTCTCGGGCCGGAGATTCGCGTCAATGCGGTCAGCCCGGG CTGGATCGATGCGCGGGATCCATCCGCGCGGCGCGCGGAACCGCTGACCGATACCGATCATGCCCAGCATCCGGCGGGCA GGGTGGGGACGGTCGAGGATGTGGCGGCGATGGTGGCGTGGTTGCTGTCGAAGAATGCGGGGTTTGTGACGGGGCAGGAA TTCGTGGTCGATGGCGGCATGACCAAGAAGATGATTTATACGGAATGA
Upstream 100 bases:
>100_bases CCGGCATTCGTGACAGCCTGATCCGCATCGCGGTCGGTCTGGAAGACGTGGCTGACCTGCAAGCCGACCTGTCGCGCGGT CTGGCGGCGTTGTGATCGAG
Downstream 100 bases:
>100_bases AGCAATTTCGTCTTTTTTAGAAAAACTTCAATCCTGCTATTGACTTAGGTTCGCTACCTGCGTAAATTTCGCGGCCTCGG AGATGCAAACGGGTGATTAG
Product: oxidoreductase
Products: (3R)-hydroxyacyl-[acyl-carrier-protein]; NADP; NADPH; Proton; beta-ketoacyl-ACP [C]
Alternate protein names: NA
Number of amino acids: Translated: 255; Mature: 254
Protein sequence:
>255_residues MSTPKIGTHGRVALVTGAARGIGLGIAAWLISEGWQVVLTDLDRVRGSKVAKVLGENAWFIAMDVADESQVALGVAEVLG QFGRLDALVCNAAVADPHNITLESLDLAYWNRVLAVNLGGPMLLAKHCAPYLRAHNGAIVNLASTRAAQSEPDTEAYAAS KGGLLALTHALAISLGPEIRVNAVSPGWIDARDPSARRAEPLTDTDHAQHPAGRVGTVEDVAAMVAWLLSKNAGFVTGQE FVVDGGMTKKMIYTE
Sequences:
>Translated_255_residues MSTPKIGTHGRVALVTGAARGIGLGIAAWLISEGWQVVLTDLDRVRGSKVAKVLGENAWFIAMDVADESQVALGVAEVLG QFGRLDALVCNAAVADPHNITLESLDLAYWNRVLAVNLGGPMLLAKHCAPYLRAHNGAIVNLASTRAAQSEPDTEAYAAS KGGLLALTHALAISLGPEIRVNAVSPGWIDARDPSARRAEPLTDTDHAQHPAGRVGTVEDVAAMVAWLLSKNAGFVTGQE FVVDGGMTKKMIYTE >Mature_254_residues STPKIGTHGRVALVTGAARGIGLGIAAWLISEGWQVVLTDLDRVRGSKVAKVLGENAWFIAMDVADESQVALGVAEVLGQ FGRLDALVCNAAVADPHNITLESLDLAYWNRVLAVNLGGPMLLAKHCAPYLRAHNGAIVNLASTRAAQSEPDTEAYAASK GGLLALTHALAISLGPEIRVNAVSPGWIDARDPSARRAEPLTDTDHAQHPAGRVGTVEDVAAMVAWLLSKNAGFVTGQEF VVDGGMTKKMIYTE
Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI5031737, Length=262, Percent_Identity=33.587786259542, Blast_Score=105, Evalue=3e-23, Organism=Homo sapiens, GI15277342, Length=252, Percent_Identity=34.1269841269841, Blast_Score=101, Evalue=7e-22, Organism=Homo sapiens, GI59889578, Length=228, Percent_Identity=33.7719298245614, Blast_Score=98, Evalue=8e-21, Organism=Homo sapiens, GI32483357, Length=251, Percent_Identity=31.8725099601594, Blast_Score=97, Evalue=2e-20, Organism=Homo sapiens, GI4758504, Length=193, Percent_Identity=35.7512953367876, Blast_Score=92, Evalue=3e-19, Organism=Homo sapiens, GI19923817, Length=267, Percent_Identity=30.3370786516854, Blast_Score=91, Evalue=9e-19, Organism=Homo sapiens, GI31542939, Length=194, Percent_Identity=31.9587628865979, Blast_Score=88, Evalue=7e-18, Organism=Homo sapiens, GI83715985, Length=180, Percent_Identity=35.5555555555556, Blast_Score=87, Evalue=2e-17, Organism=Homo sapiens, GI40254992, Length=240, Percent_Identity=30, Blast_Score=86, Evalue=3e-17, Organism=Homo sapiens, GI33667109, Length=188, Percent_Identity=35.6382978723404, Blast_Score=85, Evalue=7e-17, Organism=Homo sapiens, GI10190704, Length=246, Percent_Identity=29.6747967479675, Blast_Score=85, Evalue=7e-17, Organism=Homo sapiens, GI7705925, Length=250, Percent_Identity=34, Blast_Score=83, Evalue=2e-16, Organism=Homo sapiens, GI224922801, Length=191, Percent_Identity=31.413612565445, Blast_Score=76, Evalue=3e-14, Organism=Homo sapiens, GI20149619, Length=189, Percent_Identity=30.6878306878307, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI66933014, Length=245, Percent_Identity=26.9387755102041, Blast_Score=67, Evalue=1e-11, Organism=Homo sapiens, GI126723750, Length=254, Percent_Identity=27.1653543307087, Blast_Score=65, Evalue=6e-11, Organism=Escherichia coli, GI1787335, Length=245, Percent_Identity=31.4285714285714, Blast_Score=110, Evalue=1e-25, Organism=Escherichia coli, GI2367175, Length=246, Percent_Identity=33.739837398374, Blast_Score=100, Evalue=1e-22, Organism=Escherichia coli, GI1788459, Length=252, Percent_Identity=30.952380952381, Blast_Score=97, Evalue=1e-21, Organism=Escherichia coli, GI1790717, Length=244, Percent_Identity=28.6885245901639, Blast_Score=89, Evalue=2e-19, Organism=Escherichia coli, GI1786812, Length=250, Percent_Identity=32.4, Blast_Score=88, Evalue=5e-19, Organism=Escherichia coli, GI87082100, Length=257, Percent_Identity=31.9066147859922, Blast_Score=87, Evalue=1e-18, Organism=Escherichia coli, GI2367365, Length=241, Percent_Identity=31.9502074688797, Blast_Score=80, Evalue=2e-16, Organism=Escherichia coli, GI87082160, Length=244, Percent_Identity=27.8688524590164, Blast_Score=79, Evalue=3e-16, Organism=Escherichia coli, GI1789208, Length=244, Percent_Identity=25.8196721311475, Blast_Score=78, Evalue=6e-16, Organism=Escherichia coli, GI1787905, Length=248, Percent_Identity=27.8225806451613, Blast_Score=75, Evalue=3e-15, Organism=Escherichia coli, GI1789378, Length=245, Percent_Identity=29.7959183673469, Blast_Score=69, Evalue=3e-13, Organism=Escherichia coli, GI1788891, Length=174, Percent_Identity=31.0344827586207, Blast_Score=68, Evalue=6e-13, Organism=Escherichia coli, GI1787891, Length=240, Percent_Identity=27.5, Blast_Score=64, Evalue=7e-12, Organism=Escherichia coli, GI1787820, Length=223, Percent_Identity=25.1121076233184, Blast_Score=61, Evalue=7e-11, Organism=Caenorhabditis elegans, GI17562910, Length=263, Percent_Identity=31.1787072243346, Blast_Score=112, Evalue=2e-25, Organism=Caenorhabditis elegans, GI17561402, Length=260, Percent_Identity=30.7692307692308, Blast_Score=102, Evalue=2e-22, Organism=Caenorhabditis elegans, GI17562906, Length=259, Percent_Identity=31.2741312741313, Blast_Score=98, Evalue=3e-21, Organism=Caenorhabditis elegans, GI17559104, Length=255, Percent_Identity=29.4117647058824, Blast_Score=98, Evalue=5e-21, Organism=Caenorhabditis elegans, GI17562904, Length=267, Percent_Identity=29.9625468164794, Blast_Score=96, Evalue=2e-20, Organism=Caenorhabditis elegans, GI17560332, Length=258, Percent_Identity=28.6821705426357, Blast_Score=96, Evalue=3e-20, Organism=Caenorhabditis elegans, GI17538182, Length=195, Percent_Identity=33.8461538461538, Blast_Score=92, Evalue=2e-19, Organism=Caenorhabditis elegans, GI72000259, Length=258, Percent_Identity=29.8449612403101, Blast_Score=91, Evalue=5e-19, Organism=Caenorhabditis elegans, GI193204405, Length=257, Percent_Identity=29.5719844357977, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI17562908, Length=259, Percent_Identity=29.7297297297297, Blast_Score=88, Evalue=4e-18, Organism=Caenorhabditis elegans, GI71994600, Length=251, Percent_Identity=29.0836653386454, Blast_Score=88, Evalue=4e-18, Organism=Caenorhabditis elegans, GI17560676, Length=244, Percent_Identity=31.1475409836066, Blast_Score=88, Evalue=5e-18, Organism=Caenorhabditis elegans, GI17531453, Length=257, Percent_Identity=29.9610894941634, Blast_Score=87, Evalue=8e-18, Organism=Caenorhabditis elegans, GI17538486, Length=257, Percent_Identity=25.6809338521401, Blast_Score=87, Evalue=1e-17, Organism=Caenorhabditis elegans, GI17560220, Length=257, Percent_Identity=27.6264591439689, Blast_Score=86, Evalue=1e-17, Organism=Caenorhabditis elegans, GI25147288, Length=249, Percent_Identity=30.1204819277108, Blast_Score=86, Evalue=1e-17, Organism=Caenorhabditis elegans, GI17562990, Length=262, Percent_Identity=29.0076335877863, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17565030, Length=258, Percent_Identity=30.2325581395349, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI71994604, Length=251, Percent_Identity=28.2868525896414, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17551412, Length=258, Percent_Identity=26.7441860465116, Blast_Score=86, Evalue=3e-17, Organism=Caenorhabditis elegans, GI115534694, Length=256, Percent_Identity=32.03125, Blast_Score=85, Evalue=3e-17, Organism=Caenorhabditis elegans, GI17538480, Length=260, Percent_Identity=28.0769230769231, Blast_Score=84, Evalue=8e-17, Organism=Caenorhabditis elegans, GI17544670, Length=269, Percent_Identity=25.6505576208178, Blast_Score=81, Evalue=4e-16, Organism=Caenorhabditis elegans, GI17560150, Length=262, Percent_Identity=29.0076335877863, Blast_Score=80, Evalue=8e-16, Organism=Caenorhabditis elegans, GI17563726, Length=258, Percent_Identity=26.3565891472868, Blast_Score=80, Evalue=8e-16, Organism=Caenorhabditis elegans, GI17555706, Length=244, Percent_Identity=30.327868852459, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI71982365, Length=148, Percent_Identity=30.4054054054054, Blast_Score=65, Evalue=3e-11, Organism=Caenorhabditis elegans, GI17536025, Length=255, Percent_Identity=27.4509803921569, Blast_Score=65, Evalue=4e-11, Organism=Caenorhabditis elegans, GI17508651, Length=256, Percent_Identity=28.125, Blast_Score=64, Evalue=6e-11, Organism=Caenorhabditis elegans, GI17536651, Length=251, Percent_Identity=26.2948207171315, Blast_Score=64, Evalue=7e-11, Organism=Saccharomyces cerevisiae, GI6324126, Length=251, Percent_Identity=29.8804780876494, Blast_Score=91, Evalue=1e-19, Organism=Saccharomyces cerevisiae, GI6322227, Length=196, Percent_Identity=27.5510204081633, Blast_Score=69, Evalue=6e-13, Organism=Saccharomyces cerevisiae, GI6322226, Length=207, Percent_Identity=28.5024154589372, Blast_Score=67, Evalue=2e-12, Organism=Drosophila melanogaster, GI21355319, Length=248, Percent_Identity=34.2741935483871, Blast_Score=117, Evalue=6e-27, Organism=Drosophila melanogaster, GI23397609, Length=246, Percent_Identity=34.1463414634146, Blast_Score=115, Evalue=3e-26, Organism=Drosophila melanogaster, GI21357041, Length=246, Percent_Identity=33.739837398374, Blast_Score=105, Evalue=2e-23, Organism=Drosophila melanogaster, GI24644339, Length=248, Percent_Identity=33.0645161290323, Blast_Score=105, Evalue=3e-23, Organism=Drosophila melanogaster, GI24639444, Length=249, Percent_Identity=31.3253012048193, Blast_Score=102, Evalue=2e-22, Organism=Drosophila melanogaster, GI28571526, Length=246, Percent_Identity=31.7073170731707, Blast_Score=96, Evalue=2e-20, Organism=Drosophila melanogaster, GI17737361, Length=191, Percent_Identity=31.413612565445, Blast_Score=82, Evalue=3e-16, Organism=Drosophila melanogaster, GI24644337, Length=203, Percent_Identity=33.0049261083744, Blast_Score=81, Evalue=7e-16, Organism=Drosophila melanogaster, GI24643142, Length=249, Percent_Identity=29.718875502008, Blast_Score=77, Evalue=1e-14, Organism=Drosophila melanogaster, GI24665243, Length=183, Percent_Identity=27.8688524590164, Blast_Score=64, Evalue=8e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: 1.1.1.100 [C]
Molecular weight: Translated: 26822; Mature: 26691
Theoretical pI: Translated: 6.15; Mature: 6.15
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.8 %Cys (Translated Protein) 2.4 %Met (Translated Protein) 3.1 %Cys+Met (Translated Protein) 0.8 %Cys (Mature Protein) 2.0 %Met (Mature Protein) 2.8 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSTPKIGTHGRVALVTGAARGIGLGIAAWLISEGWQVVLTDLDRVRGSKVAKVLGENAWF CCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHCCCCEE IAMDVADESQVALGVAEVLGQFGRLDALVCNAAVADPHNITLESLDLAYWNRVLAVNLGG EEEECCCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCHHHHHHHHHCEEEEEECCC PMLLAKHCAPYLRAHNGAIVNLASTRAAQSEPDTEAYAASKGGLLALTHALAISLGPEIR HHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCHHHHCCCCCCHHHHHHHHHCCCCCEE VNAVSPGWIDARDPSARRAEPLTDTDHAQHPAGRVGTVEDVAAMVAWLLSKNAGFVTGQE EEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEECCE FVVDGGMTKKMIYTE EEEECCCCCEEEECC >Mature Secondary Structure STPKIGTHGRVALVTGAARGIGLGIAAWLISEGWQVVLTDLDRVRGSKVAKVLGENAWF CCCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHCCCCEE IAMDVADESQVALGVAEVLGQFGRLDALVCNAAVADPHNITLESLDLAYWNRVLAVNLGG EEEECCCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCHHHHHHHHHCEEEEEECCC PMLLAKHCAPYLRAHNGAIVNLASTRAAQSEPDTEAYAASKGGLLALTHALAISLGPEIR HHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCHHHHCCCCCCHHHHHHHHHCCCCCEE VNAVSPGWIDARDPSARRAEPLTDTDHAQHPAGRVGTVEDVAAMVAWLLSKNAGFVTGQE EEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEECCE FVVDGGMTKKMIYTE EEEECCCCCEEEECC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NADPH [C]
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: Oxoacyl-[acyl-carrier-protein]; NADPH; D-3-hydroxy-acyl-ACP; NADP [C]
Specific reaction: Oxoacyl-[acyl-carrier-protein] + NADPH = (3R)-hydroxyacyl-[acyl-carrier-protein] + NADP+ D-3-hydroxy-acyl-ACP + NADP = NADPH + Proton + beta-ketoacyl-ACP [C]
General reaction: Redox reaction [C]
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 7934833; 10984043 [H]