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The map label for this gene is mgtC [H]

Identifier: 77458088

GI number: 77458088

Start: 2122424

End: 2123140

Strand: Direct

Name: mgtC [H]

Synonym: Pfl01_1861

Alternate gene names: 77458088

Gene position: 2122424-2123140 (Clockwise)

Preceding gene: 77458087

Following gene: 77458089

Centisome position: 32.97

GC content: 64.02

Gene sequence:

>717_bases
ATGCAAGCGATCAACAATCTCAACCTCAGCTCATTGCTCGACACGCTGGTCAGCCTCAGCGCGGCGTTCATCCTCGGCGG
CCTGATCGGCTTCGAGCGCCAGTACCGGCAACGCACGGCGGGCTTGCGCACCAATGTGCTGGTGGCGGTCGGCGCGGCGA
TTTTCGTCGACATGGCCAACCGTCTCGCCGGTGCCGAAGGCGCGGTCCGGGTGGTCGCGTATGTGGTCTCCGGCATCGGC
TTTCTCGGTGCCGGGGTGATCATGCGCGAAGAGGGCAACGTGCGCGGCCTCAACACCGCCGCCACGCTCTGGACCTCGGC
AGCCGTCGGTGCCTGTGCCGGTGCCGACCTGCTGGCCGAAGCGGTGCTGGGCACCTTGTTCGTGCTCGCCGCCAATACCT
TGCTGCGGCCGATCGTCAACAACATCAACCGTCAGCCGCTCGATGTGGTCTCGGCGGAAGTCACCAACATCGTCTATGTC
ATTGCCCGGCGCTCGCAGCAAACGGCCGTGTTCGCCCTGCTTGAAGCGGAGCTTGAACGCAGCAACTACCCGGCCAGTGA
TGTCGATGTGCACGCCTTCGGTGCCGACGAAATCGAGATCGAAGCCACGCTCGCAACCACGTCGGTGGACGGCGATGAAC
TGGACGCACTGGTGAAGCGGATTTCCACTTCAAGCCTGGTGGTGCAGGCGTTCTGGAGTCCGAGCACCACGGAATAG

Upstream 100 bases:

>100_bases
TCAAGCAGTTAAAGGCTTCTACATCCGCCGGTTCGGCTGGCAGTAACAGGCAAGATTCCCCCCTTGTGGGAGCAAGGGGG
GCGGTTTCAAGGAGTTCGAC

Downstream 100 bases:

>100_bases
CTTTTTCAATCCGGATGAGTGACGGTGTTTTTCGGAAAAGTCCTACAGAGCGCATCCCGATGCTTGGGTAGTCTTGCCGC
CACTTGAAGCGACTACCCGG

Product: MgtC/SapB transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 238; Mature: 238

Protein sequence:

>238_residues
MQAINNLNLSSLLDTLVSLSAAFILGGLIGFERQYRQRTAGLRTNVLVAVGAAIFVDMANRLAGAEGAVRVVAYVVSGIG
FLGAGVIMREEGNVRGLNTAATLWTSAAVGACAGADLLAEAVLGTLFVLAANTLLRPIVNNINRQPLDVVSAEVTNIVYV
IARRSQQTAVFALLEAELERSNYPASDVDVHAFGADEIEIEATLATTSVDGDELDALVKRISTSSLVVQAFWSPSTTE

Sequences:

>Translated_238_residues
MQAINNLNLSSLLDTLVSLSAAFILGGLIGFERQYRQRTAGLRTNVLVAVGAAIFVDMANRLAGAEGAVRVVAYVVSGIG
FLGAGVIMREEGNVRGLNTAATLWTSAAVGACAGADLLAEAVLGTLFVLAANTLLRPIVNNINRQPLDVVSAEVTNIVYV
IARRSQQTAVFALLEAELERSNYPASDVDVHAFGADEIEIEATLATTSVDGDELDALVKRISTSSLVVQAFWSPSTTE
>Mature_238_residues
MQAINNLNLSSLLDTLVSLSAAFILGGLIGFERQYRQRTAGLRTNVLVAVGAAIFVDMANRLAGAEGAVRVVAYVVSGIG
FLGAGVIMREEGNVRGLNTAATLWTSAAVGACAGADLLAEAVLGTLFVLAANTLLRPIVNNINRQPLDVVSAEVTNIVYV
IARRSQQTAVFALLEAELERSNYPASDVDVHAFGADEIEIEATLATTSVDGDELDALVKRISTSSLVVQAFWSPSTTE

Specific function: Virulence factor required for growth in low Mg(2+) medium and for intramacrophage survival. May be involved in regulating membrane potential by activating Na(+)/K(+)-ATPase [H]

COG id: COG1285

COG function: function code S; Uncharacterized membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MgtC/SapB family [H]

Homologues:

Organism=Escherichia coli, GI1789924, Length=190, Percent_Identity=31.5789473684211, Blast_Score=79, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003416 [H]

Pfam domain/function: PF02308 MgtC [H]

EC number: NA

Molecular weight: Translated: 25022; Mature: 25022

Theoretical pI: Translated: 4.33; Mature: 4.33

Prosite motif: PS00387 PPASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQAINNLNLSSLLDTLVSLSAAFILGGLIGFERQYRQRTAGLRTNVLVAVGAAIFVDMAN
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
RLAGAEGAVRVVAYVVSGIGFLGAGVIMREEGNVRGLNTAATLWTSAAVGACAGADLLAE
HHCCCCHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
AVLGTLFVLAANTLLRPIVNNINRQPLDVVSAEVTNIVYVIARRSQQTAVFALLEAELER
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHH
SNYPASDVDVHAFGADEIEIEATLATTSVDGDELDALVKRISTSSLVVQAFWSPSTTE
CCCCCCCCEEEEECCCCEEEEEEEEEECCCHHHHHHHHHHHCCHHHEEEEECCCCCCC
>Mature Secondary Structure
MQAINNLNLSSLLDTLVSLSAAFILGGLIGFERQYRQRTAGLRTNVLVAVGAAIFVDMAN
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
RLAGAEGAVRVVAYVVSGIGFLGAGVIMREEGNVRGLNTAATLWTSAAVGACAGADLLAE
HHCCCCHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
AVLGTLFVLAANTLLRPIVNNINRQPLDVVSAEVTNIVYVIARRSQQTAVFALLEAELER
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHH
SNYPASDVDVHAFGADEIEIEATLATTSVDGDELDALVKRISTSSLVVQAFWSPSTTE
CCCCCCCCEEEEECCCCEEEEEEEEEECCCHHHHHHHHHHHCCHHHEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA