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The map label for this gene is grsT [H]

Identifier: 77458071

GI number: 77458071

Start: 2063411

End: 2064148

Strand: Direct

Name: grsT [H]

Synonym: Pfl01_1844

Alternate gene names: 77458071

Gene position: 2063411-2064148 (Clockwise)

Preceding gene: 77458069

Following gene: 77458072

Centisome position: 32.05

GC content: 64.36

Gene sequence:

>738_bases
GTGGTGACCAAGTTGACCCTGCTGTGCCTGCCGTACTCCGGCGCCAGTGCCATGGTCTACAGCCGCTGGCGGCCGAAGCT
GCCGCAGTGGCTGCAATTGCAACCGGTAGAGTTGCCGGGGCGCGGTGCCCGGTTCGGCGAACCGCTGCACACCGACATGC
GGGCACTGGCCATGCAACTGGCCAGGGAACTGCGGCCGACACTCAAGGCCCCTTACGCACTGTTCGGCCATAGCCTGGGC
GCCTTGCTGGCCTGCGAAATGGCTCATGCCTTGCGCGCGCTGGGCTGCCCGGAGCCGGTGGCACTGTTCGCCTCGGGCAC
CGCAGCGCCGACGTTGCGCGCCGATTACGACCGCGGCTTTGCCGAGCCCAAGACAGACGCCGAGCTGATCGATCAGCTGC
GCACACTCAATGGCACCAGTGAGGAAGTGCTGGCCAATGAAGAGTTGATGAGCCTGACGCTGCCGATCCTGCGCGCCGAT
TTCCTGCTGTGCGGCAAATTCCAGCCGTTGCAGCGGCCGCTGCTCAACTGCCCGGTGCACGTACTCGGCGGCAAGGCCGA
CAAGGCCACCACCGAGCAGTTGATCGGCTGGAGCAAGGAAACCCGTGGCAGTTTCTCGGTGGACATGCTGGCCGGTGGAC
ACTTCTTCATTCATGAGCACGAAGCCAAGGTGCTGCGGGTGATCAAGGATCAGCTCGACGTGCATCATCGTCGACATGGC
TTGATGGCCGCCGTCTAA

Upstream 100 bases:

>100_bases
ACGGTTAACGAGCGTTTGTAACGGAAATTTACGAACTGCCGACTAATTTGCCCGGGCAGCCATCCGTACCCTCAACAGAG
ACATTTTTTCCGAGGGAAGC

Downstream 100 bases:

>100_bases
TCCGGACTCAGTACTGTCCAGAACCCTGTGATGAGCGAGCAGGCTTGCTCCCGCAGGGTTTTTTATCGCCCGCAAATCCG
CGCTGCACCTCCCTTCTGAT

Product: thioesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 245; Mature: 245

Protein sequence:

>245_residues
MVTKLTLLCLPYSGASAMVYSRWRPKLPQWLQLQPVELPGRGARFGEPLHTDMRALAMQLARELRPTLKAPYALFGHSLG
ALLACEMAHALRALGCPEPVALFASGTAAPTLRADYDRGFAEPKTDAELIDQLRTLNGTSEEVLANEELMSLTLPILRAD
FLLCGKFQPLQRPLLNCPVHVLGGKADKATTEQLIGWSKETRGSFSVDMLAGGHFFIHEHEAKVLRVIKDQLDVHHRRHG
LMAAV

Sequences:

>Translated_245_residues
MVTKLTLLCLPYSGASAMVYSRWRPKLPQWLQLQPVELPGRGARFGEPLHTDMRALAMQLARELRPTLKAPYALFGHSLG
ALLACEMAHALRALGCPEPVALFASGTAAPTLRADYDRGFAEPKTDAELIDQLRTLNGTSEEVLANEELMSLTLPILRAD
FLLCGKFQPLQRPLLNCPVHVLGGKADKATTEQLIGWSKETRGSFSVDMLAGGHFFIHEHEAKVLRVIKDQLDVHHRRHG
LMAAV
>Mature_245_residues
MVTKLTLLCLPYSGASAMVYSRWRPKLPQWLQLQPVELPGRGARFGEPLHTDMRALAMQLARELRPTLKAPYALFGHSLG
ALLACEMAHALRALGCPEPVALFASGTAAPTLRADYDRGFAEPKTDAELIDQLRTLNGTSEEVLANEELMSLTLPILRAD
FLLCGKFQPLQRPLLNCPVHVLGGKADKATTEQLIGWSKETRGSFSVDMLAGGHFFIHEHEAKVLRVIKDQLDVHHRRHG
LMAAV

Specific function: Probable thioesterase involved in the biosynthesis of gramicidin S [H]

COG id: COG3208

COG function: function code Q; Predicted thioesterase involved in non-ribosomal peptide biosynthesis

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioesterase family [H]

Homologues:

Organism=Homo sapiens, GI89257335, Length=218, Percent_Identity=28.8990825688073, Blast_Score=99, Evalue=4e-21,
Organism=Homo sapiens, GI8922871, Length=190, Percent_Identity=30, Blast_Score=83, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012223
- InterPro:   IPR001031 [H]

Pfam domain/function: PF00975 Thioesterase [H]

EC number: NA

Molecular weight: Translated: 27049; Mature: 27049

Theoretical pI: Translated: 8.24; Mature: 8.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTKLTLLCLPYSGASAMVYSRWRPKLPQWLQLQPVELPGRGARFGEPLHTDMRALAMQL
CCCEEEEEEECCCCCCHHHHHCCCCCCCCCCEECCCCCCCCCCCCCCCHHHHHHHHHHHH
ARELRPTLKAPYALFGHSLGALLACEMAHALRALGCPEPVALFASGTAAPTLRADYDRGF
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCEECHHCCCC
AEPKTDAELIDQLRTLNGTSEEVLANEELMSLTLPILRADFLLCGKFQPLQRPLLNCPVH
CCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCEE
VLGGKADKATTEQLIGWSKETRGSFSVDMLAGGHFFIHEHEAKVLRVIKDQLDVHHRRHG
EECCCCCHHHHHHHHCCCCCCCCCEEEEEEECCEEEEEHHHHHHHHHHHHHHHHHHHHHC
LMAAV
HHHCC
>Mature Secondary Structure
MVTKLTLLCLPYSGASAMVYSRWRPKLPQWLQLQPVELPGRGARFGEPLHTDMRALAMQL
CCCEEEEEEECCCCCCHHHHHCCCCCCCCCCEECCCCCCCCCCCCCCCHHHHHHHHHHHH
ARELRPTLKAPYALFGHSLGALLACEMAHALRALGCPEPVALFASGTAAPTLRADYDRGF
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCEECHHCCCC
AEPKTDAELIDQLRTLNGTSEEVLANEELMSLTLPILRADFLLCGKFQPLQRPLLNCPVH
CCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCEE
VLGGKADKATTEQLIGWSKETRGSFSVDMLAGGHFFIHEHEAKVLRVIKDQLDVHHRRHG
EECCCCCHHHHHHHHCCCCCCCCCEEEEEEECCEEEEEHHHHHHHHHHHHHHHHHHHHHC
LMAAV
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2477357; 7512553 [H]