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The map label for this gene is ygfU [H]

Identifier: 77457928

GI number: 77457928

Start: 1896923

End: 1898281

Strand: Reverse

Name: ygfU [H]

Synonym: Pfl01_1701

Alternate gene names: 77457928

Gene position: 1898281-1896923 (Counterclockwise)

Preceding gene: 77457929

Following gene: 77457927

Centisome position: 29.48

GC content: 63.21

Gene sequence:

>1359_bases
ATGTCCGAGCTGTCCAAAGCGCGCATCCCCGACGCACCCGCCATTCAGCGCTTGCCCCTTTTGCAACTGATCCTGGTCGG
TTTGCAACATGTACTGCTGATGTACGGCGGCGCCATCGCGGTACCGTTGATCATTGGACAGGCCGCTGGCCTGAGTCGTG
AAGAAATCGCCTTCCTGATCAACGCCGACCTGCTGGTCGCCGGCATCGCCACCATCGTGCAGTCCCTGGGGATCGGCCCG
ATGGGCATACGCATGCCGGTGATGATGGGCGCCAGTTTCGCCGCCGTCGGCAGCATGGTCGCCATGGCCGGCATGCCCGG
CATCGGTCTGCAGGGAATCTTCGGCGCCACCATCGCCGCCGGGTTCTTCGGCATGATCATCGCGCCGTTCATGTCCAAGG
TCGTGCGCTTCTTCCCTCCCCTGGTGACCGGCACGGTCATCACCTCGATCGGTTTATCGTTGTTCCCCGTGGCCGTAAAC
TGGGCCGGTGGCGGCGCTGGCGCCGCACAATTCGGTTCACCGATTTACCTGGCCATCGCCGCACTGGTGCTGGCCACCAT
TCTGTTGATCCACCGCTTCATGCGTGGTTTCTGGGTCAACATTTCCGTACTGATCGGCATGTGCCTGGGCTACGTGCTCT
GCGGCGCCATCGGCATGGTCGACCTGAGCGGCATGGCCAACGCGCCGTGGGTTCAGTTCGTCACCCCGCTGCATTTCGGC
ATGCCGAAGTTCGAACTGGCACCGATCCTGTCGATGTGCCTGGTGGTGGTGATCATCTTCGTCGAGTCCACCGGTATGTT
CCTCGCACTGGGCAAAATCACCGGCCAGGAAGTCTGCCCGCGCATGCTGCGTCGCGGCCTGCTGTGTGATGCCGGCGCAT
CGTTCTTCGCCGGCTTCTTCAACACCTTCACCCACTCCTCCTTCGCGCAGAACATCGGTCTGGTGCAGATGACCGGCGTG
CGCTGCCGTTCGGTGACCATCGTTGCCGGTGGTTTGCTGATCGTCCTGAGCCTGCTGCCGAAAGCGGCGTTCCTGGTGGC
ATCGATTCCACCGGCGGTGCTCGGCGGCGCAGCGATTGCGATGTTCGGCATGGTGGCCGCCACCGGCATCAAGATCCTGC
AAGAGGCCGACATCGGCGACCGTCGCAACCAATTGCTGGTAGCCGTGAGCATCGGCATGGGCCTGATCCCGGTGGTGCGT
CCGGAATTCTTCGCCCACCTGCCGTTGTGGATGAGCCCGATCACCCACAGCGGGATCGCCATGGCCACCCTCAGCGCGCT
GACGCTGAACCTGTTGTTCAACATCCTCGGCGGCGCCGAACGCGCAGCGATCAACGACTGCCACGCACACCCGCACTGA

Upstream 100 bases:

>100_bases
TGCGATTGGCCGCATAAGCGGTCTGCCTGATGCAAAGAGGGCAGCGGCAAGCAACCCGGCCGCTGTTCATCACAAGAATA
AAAAAGATCCGAGGTGTTGC

Downstream 100 bases:

>100_bases
TCCGAAGAGTAAAAAAGGGGGCTCGCCCAAGCCTGCCCCCTCGCGACAGCTTTGCCTCAAACAATAAAAACAAGAGGGAG
CAACAGATGATCCGGACTCA

Product: xanthine/uracil permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 452; Mature: 451

Protein sequence:

>452_residues
MSELSKARIPDAPAIQRLPLLQLILVGLQHVLLMYGGAIAVPLIIGQAAGLSREEIAFLINADLLVAGIATIVQSLGIGP
MGIRMPVMMGASFAAVGSMVAMAGMPGIGLQGIFGATIAAGFFGMIIAPFMSKVVRFFPPLVTGTVITSIGLSLFPVAVN
WAGGGAGAAQFGSPIYLAIAALVLATILLIHRFMRGFWVNISVLIGMCLGYVLCGAIGMVDLSGMANAPWVQFVTPLHFG
MPKFELAPILSMCLVVVIIFVESTGMFLALGKITGQEVCPRMLRRGLLCDAGASFFAGFFNTFTHSSFAQNIGLVQMTGV
RCRSVTIVAGGLLIVLSLLPKAAFLVASIPPAVLGGAAIAMFGMVAATGIKILQEADIGDRRNQLLVAVSIGMGLIPVVR
PEFFAHLPLWMSPITHSGIAMATLSALTLNLLFNILGGAERAAINDCHAHPH

Sequences:

>Translated_452_residues
MSELSKARIPDAPAIQRLPLLQLILVGLQHVLLMYGGAIAVPLIIGQAAGLSREEIAFLINADLLVAGIATIVQSLGIGP
MGIRMPVMMGASFAAVGSMVAMAGMPGIGLQGIFGATIAAGFFGMIIAPFMSKVVRFFPPLVTGTVITSIGLSLFPVAVN
WAGGGAGAAQFGSPIYLAIAALVLATILLIHRFMRGFWVNISVLIGMCLGYVLCGAIGMVDLSGMANAPWVQFVTPLHFG
MPKFELAPILSMCLVVVIIFVESTGMFLALGKITGQEVCPRMLRRGLLCDAGASFFAGFFNTFTHSSFAQNIGLVQMTGV
RCRSVTIVAGGLLIVLSLLPKAAFLVASIPPAVLGGAAIAMFGMVAATGIKILQEADIGDRRNQLLVAVSIGMGLIPVVR
PEFFAHLPLWMSPITHSGIAMATLSALTLNLLFNILGGAERAAINDCHAHPH
>Mature_451_residues
SELSKARIPDAPAIQRLPLLQLILVGLQHVLLMYGGAIAVPLIIGQAAGLSREEIAFLINADLLVAGIATIVQSLGIGPM
GIRMPVMMGASFAAVGSMVAMAGMPGIGLQGIFGATIAAGFFGMIIAPFMSKVVRFFPPLVTGTVITSIGLSLFPVAVNW
AGGGAGAAQFGSPIYLAIAALVLATILLIHRFMRGFWVNISVLIGMCLGYVLCGAIGMVDLSGMANAPWVQFVTPLHFGM
PKFELAPILSMCLVVVIIFVESTGMFLALGKITGQEVCPRMLRRGLLCDAGASFFAGFFNTFTHSSFAQNIGLVQMTGVR
CRSVTIVAGGLLIVLSLLPKAAFLVASIPPAVLGGAAIAMFGMVAATGIKILQEADIGDRRNQLLVAVSIGMGLIPVVRP
EFFAHLPLWMSPITHSGIAMATLSALTLNLLFNILGGAERAAINDCHAHPH

Specific function: Unknown

COG id: COG2233

COG function: function code F; Xanthine/uracil permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. Nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) subfamily [H]

Homologues:

Organism=Homo sapiens, GI44680145, Length=445, Percent_Identity=25.1685393258427, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI44680143, Length=449, Percent_Identity=25.1670378619154, Blast_Score=102, Evalue=1e-21,
Organism=Homo sapiens, GI44680148, Length=467, Percent_Identity=23.982869379015, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI40316845, Length=467, Percent_Identity=23.982869379015, Blast_Score=95, Evalue=1e-19,
Organism=Escherichia coli, GI87082181, Length=438, Percent_Identity=49.7716894977169, Blast_Score=405, Evalue=1e-114,
Organism=Escherichia coli, GI1790087, Length=448, Percent_Identity=34.1517857142857, Blast_Score=190, Evalue=1e-49,
Organism=Escherichia coli, GI87082178, Length=456, Percent_Identity=29.6052631578947, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI87081818, Length=451, Percent_Identity=29.7117516629712, Blast_Score=135, Evalue=7e-33,
Organism=Escherichia coli, GI1788843, Length=454, Percent_Identity=26.6519823788546, Blast_Score=119, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI17558856, Length=497, Percent_Identity=23.3400402414487, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI71993493, Length=232, Percent_Identity=25.8620689655172, Blast_Score=75, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17542260, Length=196, Percent_Identity=27.5510204081633, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17541904, Length=448, Percent_Identity=20.9821428571429, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17542262, Length=171, Percent_Identity=29.2397660818713, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI21356175, Length=424, Percent_Identity=22.4056603773585, Blast_Score=88, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017588
- InterPro:   IPR006042
- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 47175; Mature: 47043

Theoretical pI: Translated: 8.92; Mature: 8.92

Prosite motif: PS01116 XANTH_URACIL_PERMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
5.5 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
5.3 %Met     (Mature Protein)
6.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCC
>Mature Secondary Structure 
SELSKARIPDAPAIQRLPLLQLILVGLQHVLLMYGGAIAVPLIIGQAAGLSREEIAFLI
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHH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HHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]