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The map label for this gene is mas [H]

Identifier: 77457907

GI number: 77457907

Start: 1876884

End: 1877846

Strand: Direct

Name: mas [H]

Synonym: Pfl01_1680

Alternate gene names: 77457907

Gene position: 1876884-1877846 (Clockwise)

Preceding gene: 77457904

Following gene: 77457914

Centisome position: 29.15

GC content: 62.93

Gene sequence:

>963_bases
GTGAAGGCATTGCAAGGCGTTGAAGGTCAAGTGGCATGGGTTGATGAACCAAGTCCTACATGTGATGTAGGACAAGTTCG
CATCCGGGTGGCGGCAGCGGGCCTCAATCGCGCGGATTTATTACAGAAAGCCGGTCTTTATCCACCCCCTCCAGGTGCCA
GCCACGTGCTGGGTCTTGAATGCTCCGGGGTGATCAGCGAGGTCGGCGCGGGCTCGTCCTGGCAGGTCGGTGACCGGGTC
TGCGCCTTGCTGGCCGGGGGCGGGATGGCGCAAGAGGTGGTCGTCGACGGACGGCATGTGCTGCCGGTTCCGGAAGGCGT
GTCGCTGATTGAAGCGGCGGCGTTGCCCGAGGTTTACGCGACCGTCTGGCTGAATGTGTTTCAACTCGCTGCGCTCAAAC
CGGGTGAGAAAGTTCTTCTGCACGCCGGGGCCAGTGGCATCGGCTCGGCCGCCATTCAACTGTGCAAGGCTTTCGGCAAT
CCGTGCTGGGTCAGCGTCGGCTCGGCCGAGCGGCTGGCCTACTGCGAATCGCTGGGTGCCCAGGGCGGGGTGGTGCGCAC
CGACGATCTGGAAAGCCTGCGGGATTTCGGGCCGTTCGATGTGATCCTCGATCCGGTGGGCGGCAATTATTCGGCGTTGA
ATCTGAAGTTGCTGGCCCAGGACGGACGCTGGGTGCTGATCGGTCTGATGGGCGGCCGTGAGGCAAAACTGGATCTGGCC
CAGGTGCTGGCCAAGCGCGTGCAACTGCTGGGCTCGACCCTGCGCAGCCGTGACGATCAGTTCAAGGCCGACCTGTTCAG
CGATCTGAGCCAGCACGTGTGGCCGCTGTTTTCCGAAGGGCGCCTGAAGCCGCAACTGGCCAAGGCTTTCCCGATCAAGG
ATGCCGAGGCTGCGTTTGCAGAGCTTGCGAGCAACACCGTGGCAGGGAAGCTGGTGCTGGTGATCGACGAAAGCCTGAGC
TGA

Upstream 100 bases:

>100_bases
CTGCTGTTCAGCGTTCGTTCAGACCCCAGGGCCGGTCGCATAATGCAAAAAGCCCGGCGCTACAGCTTCGGGCTCAGTCC
AGACTCACTATGGAGGCACT

Downstream 100 bases:

>100_bases
TCATCATTGCTTGTGGGAGCAGGTCTGCTCCCACAAGACCATCGCTTACTTCCAGAGGTGGATCGGCCAGCCGGACTTCT
CGGCCTCTGCCAGCAACACC

Product: zinc-containing alcohol dehydrogenase superfamily protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 320; Mature: 320

Protein sequence:

>320_residues
MKALQGVEGQVAWVDEPSPTCDVGQVRIRVAAAGLNRADLLQKAGLYPPPPGASHVLGLECSGVISEVGAGSSWQVGDRV
CALLAGGGMAQEVVVDGRHVLPVPEGVSLIEAAALPEVYATVWLNVFQLAALKPGEKVLLHAGASGIGSAAIQLCKAFGN
PCWVSVGSAERLAYCESLGAQGGVVRTDDLESLRDFGPFDVILDPVGGNYSALNLKLLAQDGRWVLIGLMGGREAKLDLA
QVLAKRVQLLGSTLRSRDDQFKADLFSDLSQHVWPLFSEGRLKPQLAKAFPIKDAEAAFAELASNTVAGKLVLVIDESLS

Sequences:

>Translated_320_residues
MKALQGVEGQVAWVDEPSPTCDVGQVRIRVAAAGLNRADLLQKAGLYPPPPGASHVLGLECSGVISEVGAGSSWQVGDRV
CALLAGGGMAQEVVVDGRHVLPVPEGVSLIEAAALPEVYATVWLNVFQLAALKPGEKVLLHAGASGIGSAAIQLCKAFGN
PCWVSVGSAERLAYCESLGAQGGVVRTDDLESLRDFGPFDVILDPVGGNYSALNLKLLAQDGRWVLIGLMGGREAKLDLA
QVLAKRVQLLGSTLRSRDDQFKADLFSDLSQHVWPLFSEGRLKPQLAKAFPIKDAEAAFAELASNTVAGKLVLVIDESLS
>Mature_320_residues
MKALQGVEGQVAWVDEPSPTCDVGQVRIRVAAAGLNRADLLQKAGLYPPPPGASHVLGLECSGVISEVGAGSSWQVGDRV
CALLAGGGMAQEVVVDGRHVLPVPEGVSLIEAAALPEVYATVWLNVFQLAALKPGEKVLLHAGASGIGSAAIQLCKAFGN
PCWVSVGSAERLAYCESLGAQGGVVRTDDLESLRDFGPFDVILDPVGGNYSALNLKLLAQDGRWVLIGLMGGREAKLDLA
QVLAKRVQLLGSTLRSRDDQFKADLFSDLSQHVWPLFSEGRLKPQLAKAFPIKDAEAAFAELASNTVAGKLVLVIDESLS

Specific function: Catalyzes the elongation of N-fatty acyl-CoA with methylamalonyl-CoA (not malonyl-CoA) as the elongating agent to form mycocerosyl lipids [H]

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 acyl carrier domain [H]

Homologues:

Organism=Homo sapiens, GI22538446, Length=322, Percent_Identity=43.167701863354, Blast_Score=222, Evalue=4e-58,
Organism=Homo sapiens, GI22538444, Length=322, Percent_Identity=43.167701863354, Blast_Score=222, Evalue=4e-58,
Organism=Homo sapiens, GI18379349, Length=311, Percent_Identity=29.903536977492, Blast_Score=125, Evalue=5e-29,
Organism=Homo sapiens, GI24308257, Length=320, Percent_Identity=24.6875, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI194239674, Length=299, Percent_Identity=26.7558528428094, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI13236495, Length=299, Percent_Identity=26.7558528428094, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI41872631, Length=326, Percent_Identity=26.9938650306748, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI28557745, Length=240, Percent_Identity=29.5833333333333, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI194239676, Length=294, Percent_Identity=24.8299319727891, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI47519420, Length=331, Percent_Identity=24.773413897281, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI67078404, Length=304, Percent_Identity=25.6578947368421, Blast_Score=66, Evalue=4e-11,
Organism=Escherichia coli, GI1790485, Length=307, Percent_Identity=28.3387622149837, Blast_Score=87, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17507255, Length=310, Percent_Identity=28.0645161290323, Blast_Score=94, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI212642053, Length=335, Percent_Identity=26.865671641791, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI71987554, Length=371, Percent_Identity=24.7978436657682, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17536829, Length=282, Percent_Identity=26.5957446808511, Blast_Score=65, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6319520, Length=323, Percent_Identity=26.0061919504644, Blast_Score=83, Evalue=7e-17,
Organism=Drosophila melanogaster, GI19920632, Length=271, Percent_Identity=25.830258302583, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI221330659, Length=271, Percent_Identity=25.830258302583, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24581345, Length=333, Percent_Identity=25.5255255255255, Blast_Score=75, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR009081
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR000794
- InterPro:   IPR011032
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016036
- InterPro:   IPR016040
- InterPro:   IPR006163
- InterPro:   IPR020842
- InterPro:   IPR020801
- InterPro:   IPR020841
- InterPro:   IPR020807
- InterPro:   IPR020843
- InterPro:   IPR013968
- InterPro:   IPR006162
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00698 Acyl_transf_1; PF08240 ADH_N; PF00107 ADH_zinc_N; PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C; PF08659 KR; PF00550 PP-binding [H]

EC number: =2.3.1.111 [H]

Molecular weight: Translated: 33583; Mature: 33583

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKALQGVEGQVAWVDEPSPTCDVGQVRIRVAAAGLNRADLLQKAGLYPPPPGASHVLGLE
CCCCCCCCCEEEEECCCCCCCCCCCEEEEEEECCCCHHHHHHHCCCCCCCCCCCCEEEEE
CSGVISEVGAGSSWQVGDRVCALLAGGGMAQEVVVDGRHVLPVPEGVSLIEAAALPEVYA
HHHHHHHHCCCCCCCHHHHHHHHHHCCCCHHHHEECCCEEECCCCCHHHHHHHHHHHHHH
TVWLNVFQLAALKPGEKVLLHAGASGIGSAAIQLCKAFGNPCWVSVGSAERLAYCESLGA
HHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHCCC
QGGVVRTDDLESLRDFGPFDVILDPVGGNYSALNLKLLAQDGRWVLIGLMGGREAKLDLA
CCCEEECCCHHHHHCCCCEEEEEECCCCCEEEEEEEEEECCCCEEEEEECCCCCHHHHHH
QVLAKRVQLLGSTLRSRDDQFKADLFSDLSQHVWPLFSEGRLKPQLAKAFPIKDAEAAFA
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHCCCCCCHHHHHHCCCCCHHHHHH
ELASNTVAGKLVLVIDESLS
HHHCCCCCCEEEEEEECCCC
>Mature Secondary Structure
MKALQGVEGQVAWVDEPSPTCDVGQVRIRVAAAGLNRADLLQKAGLYPPPPGASHVLGLE
CCCCCCCCCEEEEECCCCCCCCCCCEEEEEEECCCCHHHHHHHCCCCCCCCCCCCEEEEE
CSGVISEVGAGSSWQVGDRVCALLAGGGMAQEVVVDGRHVLPVPEGVSLIEAAALPEVYA
HHHHHHHHCCCCCCCHHHHHHHHHHCCCCHHHHEECCCEEECCCCCHHHHHHHHHHHHHH
TVWLNVFQLAALKPGEKVLLHAGASGIGSAAIQLCKAFGNPCWVSVGSAERLAYCESLGA
HHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHCCC
QGGVVRTDDLESLRDFGPFDVILDPVGGNYSALNLKLLAQDGRWVLIGLMGGREAKLDLA
CCCEEECCCHHHHHCCCCEEEEEECCCCCEEEEEEEEEECCCCEEEEEECCCCCHHHHHH
QVLAKRVQLLGSTLRSRDDQFKADLFSDLSQHVWPLFSEGRLKPQLAKAFPIKDAEAAFA
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHCCCCCCHHHHHHCCCCCHHHHHH
ELASNTVAGKLVLVIDESLS
HHHCCCCCCEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1527058; 12788972 [H]