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The map label for this gene is actP [H]

Identifier: 77457835

GI number: 77457835

Start: 1795212

End: 1796870

Strand: Direct

Name: actP [H]

Synonym: Pfl01_1608

Alternate gene names: 77457835

Gene position: 1795212-1796870 (Clockwise)

Preceding gene: 77457834

Following gene: 77457837

Centisome position: 27.88

GC content: 60.4

Gene sequence:

>1659_bases
ATGATCCGGCGTCTACTGGCTCTTTTGAGCATCGCAGCGTTCGCTCCGGCCGTCTGGGCCGCTGACGCCCTGACCGGCGA
AGTCCACAAACAACCACTCAACGTTTCCGCGATCGTCATGTTCGTGGTGTTCGTTGGCGCGACCCTGTGCATCACCTACT
GGGCGTCCAAGCGCAACAAGTCGGCGGCCGACTACTATGCGGCGGGCGGCAAGATCACCGGTTTCCAGAACGGTCTGGCA
ATTGCCGGTGACTACATGTCGGCGGCGTCCTTCCTGGGTATTTCCGCGCTGGTGTTCACCTCCGGCTACGACGGCCTGAT
CTACTCGATCGGCTTCCTGGTGGGCTGGCCGATCATTCTGTTCCTGATCGCCGAGCGTCTGCGTAACTTGGGTAAATACA
CCTTTGCCGACGTGGCGTCCTACCGCCTCGGGCAAACCCAGATCCGCACCCTGTCGGCCTGCGGTTCGCTGGTGGTGGTA
GCGTTCTACCTGATCGCGCAAATGGTCGGTGCCGGCAAGCTGATCCAGCTGCTGTTCGGTCTCGACTACCACGTCGCGGT
GATTCTGGTCGGTATCCTGATGTGCCTGTACGTGCTGTTCGGCGGCATGCTGGCGACTACCTGGGTGCAGATCATCAAGG
CGGTGCTGTTGCTGTCCGGTGCCTCGTTCATGGCGCTGATGGTGATGAAGCACGTCAACTTCGACTTCAACACCCTGTTC
TCCGAAGCCATCAAGGTTCACGCCAAGGGTGAAGCGATCATGAGCCCGGGCGGTCTGGTCAAAGACCCGATCTCGGCGTT
CTCCCTGGGTCTGGCGCTGATGTTCGGTACCGCCGGCCTGCCGCACATCCTGATGCGCTTCTTCACCGTTAGCGACGCGA
AAGAAGCCCGTAAGAGCGTGCTGTACGCGACCGGTTTCATTGGCTACTTCTACATCCTGACCTTCATCATCGGCTTCGGC
GCGATCCTGCTGGTCAGCACCAACCCGGCCTTCAAAGATGCGGCGGGCGCTCTACTCGGCGGCAACAACATGGCGGCGGT
GCACCTGGCCAATGCCGTGGGCGGCAGCGTGTTCCTCGGCTTCATCTCGGCGGTAGCGTTCGCGACCATTCTGGCGGTCG
TGGCCGGTCTGACCCTGGCCGGGGCTTCGGCGGTGTCTCACGACCTGTACGCCAGCGTGATCAAGAAGGGCAAGGCCAAC
GAGAAGGATGAGATCCGCGTTTCGAAGATCACCACCATCGCGCTGGGCGTTCTGGCCATTGGCCTGGGCATCCTGTTCGA
AAGCCAGAACATTGCGTTCATGGTTGGCCTGGCGTTCTCCATCGCGGCAAGCTGCAACTTCCCGGTGCTGCTGCTTTCGA
TGTACTGGAAGAAGCTGACCACTCGTGGCGCCATGATTGGCGGCTGGCTGGGCCTGGTGAGTGCGGTGGGTCTGATGATT
CTTGGCCCGACCATCTGGGTGCAGATTCTGCATCATGAGAAGGCGATCTTCCCTTACGAGTATCCGGCGTTGTTCTCGAT
GATCATTGCGTTTATCGGGATCTGGTTCTTCTCGGTCACCGATAAGTCGGCCGAAGCCGAGAATGAGCGTGCGCTGTTCT
TCCCGCAGTTTGTGCGTTCGCAGACTGGGTTGGGGGCTAGTGGGGCGGTTTCGCACTGA

Upstream 100 bases:

>100_bases
GACTGATTGTCTCGGCCTTCATCCTGACCGGCATTTACGTGCGCCGCGCCAATGGCGAGTTCGACGACCTGAACAACGCG
ATTCTCAAGGAGGCTCAGCA

Downstream 100 bases:

>100_bases
GGCTTTTTGTGTAGGTTGAGTTGAATGAAAATGCCCTGGTCGAGAGATTGGGGCATTTTTTTGTGGGCGGTTATCGGATG
TTCTTGGGGGTTGGGTGTAT

Product: acetate permease

Products: NA

Alternate protein names: Acetate permease; Acetate transporter ActP [H]

Number of amino acids: Translated: 552; Mature: 552

Protein sequence:

>552_residues
MIRRLLALLSIAAFAPAVWAADALTGEVHKQPLNVSAIVMFVVFVGATLCITYWASKRNKSAADYYAAGGKITGFQNGLA
IAGDYMSAASFLGISALVFTSGYDGLIYSIGFLVGWPIILFLIAERLRNLGKYTFADVASYRLGQTQIRTLSACGSLVVV
AFYLIAQMVGAGKLIQLLFGLDYHVAVILVGILMCLYVLFGGMLATTWVQIIKAVLLLSGASFMALMVMKHVNFDFNTLF
SEAIKVHAKGEAIMSPGGLVKDPISAFSLGLALMFGTAGLPHILMRFFTVSDAKEARKSVLYATGFIGYFYILTFIIGFG
AILLVSTNPAFKDAAGALLGGNNMAAVHLANAVGGSVFLGFISAVAFATILAVVAGLTLAGASAVSHDLYASVIKKGKAN
EKDEIRVSKITTIALGVLAIGLGILFESQNIAFMVGLAFSIAASCNFPVLLLSMYWKKLTTRGAMIGGWLGLVSAVGLMI
LGPTIWVQILHHEKAIFPYEYPALFSMIIAFIGIWFFSVTDKSAEAENERALFFPQFVRSQTGLGASGAVSH

Sequences:

>Translated_552_residues
MIRRLLALLSIAAFAPAVWAADALTGEVHKQPLNVSAIVMFVVFVGATLCITYWASKRNKSAADYYAAGGKITGFQNGLA
IAGDYMSAASFLGISALVFTSGYDGLIYSIGFLVGWPIILFLIAERLRNLGKYTFADVASYRLGQTQIRTLSACGSLVVV
AFYLIAQMVGAGKLIQLLFGLDYHVAVILVGILMCLYVLFGGMLATTWVQIIKAVLLLSGASFMALMVMKHVNFDFNTLF
SEAIKVHAKGEAIMSPGGLVKDPISAFSLGLALMFGTAGLPHILMRFFTVSDAKEARKSVLYATGFIGYFYILTFIIGFG
AILLVSTNPAFKDAAGALLGGNNMAAVHLANAVGGSVFLGFISAVAFATILAVVAGLTLAGASAVSHDLYASVIKKGKAN
EKDEIRVSKITTIALGVLAIGLGILFESQNIAFMVGLAFSIAASCNFPVLLLSMYWKKLTTRGAMIGGWLGLVSAVGLMI
LGPTIWVQILHHEKAIFPYEYPALFSMIIAFIGIWFFSVTDKSAEAENERALFFPQFVRSQTGLGASGAVSH
>Mature_552_residues
MIRRLLALLSIAAFAPAVWAADALTGEVHKQPLNVSAIVMFVVFVGATLCITYWASKRNKSAADYYAAGGKITGFQNGLA
IAGDYMSAASFLGISALVFTSGYDGLIYSIGFLVGWPIILFLIAERLRNLGKYTFADVASYRLGQTQIRTLSACGSLVVV
AFYLIAQMVGAGKLIQLLFGLDYHVAVILVGILMCLYVLFGGMLATTWVQIIKAVLLLSGASFMALMVMKHVNFDFNTLF
SEAIKVHAKGEAIMSPGGLVKDPISAFSLGLALMFGTAGLPHILMRFFTVSDAKEARKSVLYATGFIGYFYILTFIIGFG
AILLVSTNPAFKDAAGALLGGNNMAAVHLANAVGGSVFLGFISAVAFATILAVVAGLTLAGASAVSHDLYASVIKKGKAN
EKDEIRVSKITTIALGVLAIGLGILFESQNIAFMVGLAFSIAASCNFPVLLLSMYWKKLTTRGAMIGGWLGLVSAVGLMI
LGPTIWVQILHHEKAIFPYEYPALFSMIIAFIGIWFFSVTDKSAEAENERALFFPQFVRSQTGLGASGAVSH

Specific function: Transports acetate [H]

COG id: COG4147

COG function: function code R; Predicted symporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

Organism=Homo sapiens, GI310128183, Length=458, Percent_Identity=24.0174672489083, Blast_Score=98, Evalue=2e-20,
Organism=Escherichia coli, GI1790503, Length=552, Percent_Identity=79.3478260869565, Blast_Score=869, Evalue=0.0,
Organism=Escherichia coli, GI1787251, Length=476, Percent_Identity=25.4201680672269, Blast_Score=96, Evalue=6e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014083
- InterPro:   IPR001734
- InterPro:   IPR018212
- InterPro:   IPR019900 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 58767; Mature: 58767

Theoretical pI: Translated: 9.57; Mature: 9.57

Prosite motif: PS00456 NA_SOLUT_SYMP_1 ; PS00457 NA_SOLUT_SYMP_2 ; PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCCCCCCCCC
>Mature Secondary Structure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CCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA