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The map label for this gene is atoS [H]

Identifier: 77457760

GI number: 77457760

Start: 1721306

End: 1722517

Strand: Direct

Name: atoS [H]

Synonym: Pfl01_1533

Alternate gene names: 77457760

Gene position: 1721306-1722517 (Clockwise)

Preceding gene: 77457759

Following gene: 77457761

Centisome position: 26.73

GC content: 63.61

Gene sequence:

>1212_bases
ATGCCCCAAGCCTCCCAGATGTCTTCTGTTCCCGAGTCCTCGGGGCAACTGCCGTCCGTAGAGCAGGCGAGCCGCCAGGG
GCTTGAGCAGGCATTCGCCCTGTTCAACCAGATGTCCAGCCAGTTGACCGATTCCTACAGCATGCTCGAAGCCCGGGTCA
CCGAGCTCAAGGGCGAGCTGGCCGTGGTCAGCGCCCAGCGCATGCAGGAACTGGCGGAAAAAGAACGCTTGGCCAACCGT
CTGCAAAATCTCCTCGATCTGTTGCCCGGTGGCGTCATCGTCATCGACGGTCACGGCATTGTGTGCGAGGCCAATCCTGC
CGCCATCGAATTGCTCGGCCTGCCGCTGGAAGGTGAGCTGTGGCGCCATGTCATCGCCCGTTGCTTTGCGCCCCGTGAGG
ACGACGGTCACGAAATTTCCTTGAAGAACGGTCGACGCCTGTCGATTGCCACCCGCTCGCTGGATGCCGAGCCGGGGCAG
TTGGTGCTGCTCAACGACCTGACTGAAACCCGTCACTTGCAGGATCAGCTGGCCCGCCACGAGCGGCTGTCGTCCCTGGG
GCGGATGGTCGCGTCGCTGGCGCATCAGATCCGCACGCCATTGTCCGCCGCCTTGTTGTACGCCAGTCATTTGACCGAGC
AGGAACTGCCGGTCGCCACCCAGCAGCGTTTTGCCGGGCGCCTCAAGGAGCGCCTGCACGAACTGGAGCATCAGGTGCGC
GACATGCTGGTCTTCGCCCGTGGCGAGCTGCCGCTGACCGACCGTGTCACGCCGAATGCCTTGATGCAGTCGTTGCAGGC
GGCGGCGCTGACCCATGTGCAGGACCTGCCGATCCGCTGGCAGTGCGACAGCCATGCCGGCGAGTTGCTGTGCAATCGCG
ACACGCTGGTCGGGGCGCTGCTCAATCTGATTGAAAACGCCATTCAGGCGAGTGCTGGTGAGGTGCGTCTGAAGGTGCAT
TGCTATACCCGCGACAACACCCTGCGTTTGTGTGTCAGTGACAGCGGCAGCGGTATTGATGCGGCGGTGCTGGCGCGGCT
GGGCGAGCCGTTTTTCACCACCAAAGTTACCGGGACCGGCCTGGGCCTGACCGTGGTCAAGGCCGTGGCGCGTGCGCATC
AGGGAGAATTGCAGCTGCGTTCGCGGGTCGGGCGCGGTACGTGCGCGCAGGTCATCCTGCCGTTGTTTTCTGCTGTACAG
GGAGCTGAGTGA

Upstream 100 bases:

>100_bases
TCAACCGCTTCATTTATAAGCGGTTTTTTTTAGGCACGGGTATTGCTACGTCCCTCGCAACGTTCCGTTTAACTGACGGT
CAGCCAAGCGAGAGAGCACA

Downstream 100 bases:

>100_bases
AGGTCATGGGCATCAAGGTTCTGCTGGTCGAGGATGACCGCTCGTTGCGCGAAGCGCTGGCCGATACGCTGCTGCTGGCC
GGTCACGACTATCACGCGGT

Product: PAS/PAC sensor Signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 403; Mature: 402

Protein sequence:

>403_residues
MPQASQMSSVPESSGQLPSVEQASRQGLEQAFALFNQMSSQLTDSYSMLEARVTELKGELAVVSAQRMQELAEKERLANR
LQNLLDLLPGGVIVIDGHGIVCEANPAAIELLGLPLEGELWRHVIARCFAPREDDGHEISLKNGRRLSIATRSLDAEPGQ
LVLLNDLTETRHLQDQLARHERLSSLGRMVASLAHQIRTPLSAALLYASHLTEQELPVATQQRFAGRLKERLHELEHQVR
DMLVFARGELPLTDRVTPNALMQSLQAAALTHVQDLPIRWQCDSHAGELLCNRDTLVGALLNLIENAIQASAGEVRLKVH
CYTRDNTLRLCVSDSGSGIDAAVLARLGEPFFTTKVTGTGLGLTVVKAVARAHQGELQLRSRVGRGTCAQVILPLFSAVQ
GAE

Sequences:

>Translated_403_residues
MPQASQMSSVPESSGQLPSVEQASRQGLEQAFALFNQMSSQLTDSYSMLEARVTELKGELAVVSAQRMQELAEKERLANR
LQNLLDLLPGGVIVIDGHGIVCEANPAAIELLGLPLEGELWRHVIARCFAPREDDGHEISLKNGRRLSIATRSLDAEPGQ
LVLLNDLTETRHLQDQLARHERLSSLGRMVASLAHQIRTPLSAALLYASHLTEQELPVATQQRFAGRLKERLHELEHQVR
DMLVFARGELPLTDRVTPNALMQSLQAAALTHVQDLPIRWQCDSHAGELLCNRDTLVGALLNLIENAIQASAGEVRLKVH
CYTRDNTLRLCVSDSGSGIDAAVLARLGEPFFTTKVTGTGLGLTVVKAVARAHQGELQLRSRVGRGTCAQVILPLFSAVQ
GAE
>Mature_402_residues
PQASQMSSVPESSGQLPSVEQASRQGLEQAFALFNQMSSQLTDSYSMLEARVTELKGELAVVSAQRMQELAEKERLANRL
QNLLDLLPGGVIVIDGHGIVCEANPAAIELLGLPLEGELWRHVIARCFAPREDDGHEISLKNGRRLSIATRSLDAEPGQL
VLLNDLTETRHLQDQLARHERLSSLGRMVASLAHQIRTPLSAALLYASHLTEQELPVATQQRFAGRLKERLHELEHQVRD
MLVFARGELPLTDRVTPNALMQSLQAAALTHVQDLPIRWQCDSHAGELLCNRDTLVGALLNLIENAIQASAGEVRLKVHC
YTRDNTLRLCVSDSGSGIDAAVLARLGEPFFTTKVTGTGLGLTVVKAVARAHQGELQLRSRVGRGTCAQVILPLFSAVQG
AE

Specific function: Member of the two-component regulatory system AtoS/AtoC; may activate AtoC by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=385, Percent_Identity=30.3896103896104, Blast_Score=138, Evalue=8e-34,
Organism=Escherichia coli, GI1790436, Length=225, Percent_Identity=31.5555555555556, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1786600, Length=357, Percent_Identity=23.8095238095238, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI48994928, Length=378, Percent_Identity=23.5449735449735, Blast_Score=65, Evalue=9e-12,
Organism=Escherichia coli, GI1786783, Length=260, Percent_Identity=26.9230769230769, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 44012; Mature: 43881

Theoretical pI: Translated: 6.45; Mature: 6.45

Prosite motif: PS50112 PAS ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPQASQMSSVPESSGQLPSVEQASRQGLEQAFALFNQMSSQLTDSYSMLEARVTELKGEL
CCCHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
AVVSAQRMQELAEKERLANRLQNLLDLLPGGVIVIDGHGIVCEANPAAIELLGLPLEGEL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEEEEECCCCEEEEEECCCCHHH
WRHVIARCFAPREDDGHEISLKNGRRLSIATRSLDAEPGQLVLLNDLTETRHLQDQLARH
HHHHHHHHCCCCCCCCCEEEECCCCEEEEEECCCCCCCCCEEEEECCHHHHHHHHHHHHH
ERLSSLGRMVASLAHQIRTPLSAALLYASHLTEQELPVATQQRFAGRLKERLHELEHQVR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCHHHHHHHHHHHHHHHHHHHHHHH
DMLVFARGELPLTDRVTPNALMQSLQAAALTHVQDLPIRWQCDSHAGELLCNRDTLVGAL
HHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCEEECCHHHHHHH
LNLIENAIQASAGEVRLKVHCYTRDNTLRLCVSDSGSGIDAAVLARLGEPFFTTKVTGTG
HHHHHHHHHCCCCCEEEEEEEEECCCEEEEEECCCCCCHHHHHHHHCCCCCEEEEECCCC
LGLTVVKAVARAHQGELQLRSRVGRGTCAQVILPLFSAVQGAE
CHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
PQASQMSSVPESSGQLPSVEQASRQGLEQAFALFNQMSSQLTDSYSMLEARVTELKGEL
CCHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
AVVSAQRMQELAEKERLANRLQNLLDLLPGGVIVIDGHGIVCEANPAAIELLGLPLEGEL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEEEEECCCCEEEEEECCCCHHH
WRHVIARCFAPREDDGHEISLKNGRRLSIATRSLDAEPGQLVLLNDLTETRHLQDQLARH
HHHHHHHHCCCCCCCCCEEEECCCCEEEEEECCCCCCCCCEEEEECCHHHHHHHHHHHHH
ERLSSLGRMVASLAHQIRTPLSAALLYASHLTEQELPVATQQRFAGRLKERLHELEHQVR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCHHHHHHHHHHHHHHHHHHHHHHH
DMLVFARGELPLTDRVTPNALMQSLQAAALTHVQDLPIRWQCDSHAGELLCNRDTLVGAL
HHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCEEECCHHHHHHH
LNLIENAIQASAGEVRLKVHCYTRDNTLRLCVSDSGSGIDAAVLARLGEPFFTTKVTGTG
HHHHHHHHHCCCCCEEEEEEEEECCCEEEEEECCCCCCHHHHHHHHCCCCCEEEEECCCC
LGLTVVKAVARAHQGELQLRSRVGRGTCAQVILPLFSAVQGAE
CHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8346225; 9097040; 9278503 [H]