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The map label for this gene is ntrC [H]

Identifier: 77457759

GI number: 77457759

Start: 1719720

End: 1721195

Strand: Direct

Name: ntrC [H]

Synonym: Pfl01_1532

Alternate gene names: 77457759

Gene position: 1719720-1721195 (Clockwise)

Preceding gene: 77457758

Following gene: 77457760

Centisome position: 26.71

GC content: 61.72

Gene sequence:

>1476_bases
ATGTGGCGTGAAACCAAAATTCTGCTGATCGATGACGATAGCGTCCGCCGCCGCGACCTGGCGGTGATTTTAAATTTTCT
TGGCGAAGAAAATTTACCCTGCGGAAGCCATGACTGGCAGCAGGCAGTCGGCTCTTTGTCGTCTAGTCGTGAGGTCATTT
GCGTACTGATCGGGACGGTCAATGCTCCTGGTGCGCTTTTGGGCTTGCTAAAGACACTCTCAACCTGGGATGAGTTCCTT
CCGGTTTTGCTGATGGGCGATAATTCTTCGGTGGACCTGCCCGAAGACCAGCGCCGCCGGGTGCTTTCGACCCTCGAAAT
GCCGCCGAGCTACAGCAAGCTGCTCGACTCCCTGCACCGTGCCCAGGTCTATCGCGAGATGTACGACCAGGCCCGCGAAC
GCGGCCGTCATCGCGAACCCAACCTTTTCCGCAGTCTCGTCGGCACCAGTCGCGCGATCCAGCACGTGCGCCAGATGATG
CAGCAAGTGGCCGACACCGATGCCAGCGTGCTGATCCTCGGCGAGTCCGGGACCGGCAAGGAAGTGGTTGCGCGCAACCT
GCATTACCATTCCAAGCGTCGTGACGCGCCATTCGTACCGGTCAACTGCGGGGCGATCCCGGCCGAGTTGCTGGAAAGCG
AACTGTTCGGCCACGAGAAGGGCGCCTTTACCGGCGCTATCACCAGCCGTGCCGGCCGCTTCGAGCTGGCCAACGGCGGT
ACGCTGTTCCTCGACGAAATCGGCGACATGCCGCTGCCGATGCAGGTCAAGCTGCTGCGCGTGCTGCAGGAGCGCACCTT
CGAGCGTGTGGGCAGCAACAAGACCCAGAGCGTCGACGTGCGCATCATCGCCGCGACCCACAAGAATCTCGAAAGCATGA
TCGAGATCGGCACCTTCCGCGAAGACCTCTACTATCGCCTGAACGTGTTCCCGATCGAGATGGCGCCGCTGCGTGAGCGC
GTCGAAGACATTCCGCTGCTGATGAACGAGCTGATCTCGCGCATGGAGCACGAGAAGCGCGGTTCGATCCGCTTCAACTC
TGCCGCGATCATGTCCCTGTGCCGCCACGGCTGGCCGGGCAACGTCCGCGAGCTGGCCAACCTGGTGGAGCGCATGGCGA
TCATGCATCCTTACGGGGTGATCGGCGTGGTCGAGCTGCCGAAGAAATTCCGCTACGTCGACGACGAAGACGAGCAAATG
GTCGACAGCCTGCGCAGCGATCTGGAAGAGCGCGTGGCGATCAACGGCCATACGCCGGACTTCACCGCCAACGCCATGCT
GCCGCCGGAAGGTCTCGACCTGAAGGACTACCTCGGTGGTCTGGAGCAGGGGCTGATCCAGCAGGCGCTGGACGACGCCA
ACGGCATCGTGGCCCGTGCCGCCGAACGCCTGCGTATTCGCCGCACCACGCTGGTGGAGAAGATGCGCAAGTACGGCATG
AGCCGCCGTGAAGGAGATGAACAGGCGGATGATTGA

Upstream 100 bases:

>100_bases
TGTTTTCAGATTTCAGGCGTCTACAGGCACAAGGTGTCCTGCAAGCGTCTCGCTTGCCCCTCATTTTGGGCATTGAGTTG
ACTAGGGAAGTTGCTATTGC

Downstream 100 bases:

>100_bases
CGCCTGTTTTTCAACCGCTTCATTTATAAGCGGTTTTTTTTAGGCACGGGTATTGCTACGTCCCTCGCAACGTTCCGTTT
AACTGACGGTCAGCCAAGCG

Product: sigma-54 dependent trancsriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 491; Mature: 491

Protein sequence:

>491_residues
MWRETKILLIDDDSVRRRDLAVILNFLGEENLPCGSHDWQQAVGSLSSSREVICVLIGTVNAPGALLGLLKTLSTWDEFL
PVLLMGDNSSVDLPEDQRRRVLSTLEMPPSYSKLLDSLHRAQVYREMYDQARERGRHREPNLFRSLVGTSRAIQHVRQMM
QQVADTDASVLILGESGTGKEVVARNLHYHSKRRDAPFVPVNCGAIPAELLESELFGHEKGAFTGAITSRAGRFELANGG
TLFLDEIGDMPLPMQVKLLRVLQERTFERVGSNKTQSVDVRIIAATHKNLESMIEIGTFREDLYYRLNVFPIEMAPLRER
VEDIPLLMNELISRMEHEKRGSIRFNSAAIMSLCRHGWPGNVRELANLVERMAIMHPYGVIGVVELPKKFRYVDDEDEQM
VDSLRSDLEERVAINGHTPDFTANAMLPPEGLDLKDYLGGLEQGLIQQALDDANGIVARAAERLRIRRTTLVEKMRKYGM
SRREGDEQADD

Sequences:

>Translated_491_residues
MWRETKILLIDDDSVRRRDLAVILNFLGEENLPCGSHDWQQAVGSLSSSREVICVLIGTVNAPGALLGLLKTLSTWDEFL
PVLLMGDNSSVDLPEDQRRRVLSTLEMPPSYSKLLDSLHRAQVYREMYDQARERGRHREPNLFRSLVGTSRAIQHVRQMM
QQVADTDASVLILGESGTGKEVVARNLHYHSKRRDAPFVPVNCGAIPAELLESELFGHEKGAFTGAITSRAGRFELANGG
TLFLDEIGDMPLPMQVKLLRVLQERTFERVGSNKTQSVDVRIIAATHKNLESMIEIGTFREDLYYRLNVFPIEMAPLRER
VEDIPLLMNELISRMEHEKRGSIRFNSAAIMSLCRHGWPGNVRELANLVERMAIMHPYGVIGVVELPKKFRYVDDEDEQM
VDSLRSDLEERVAINGHTPDFTANAMLPPEGLDLKDYLGGLEQGLIQQALDDANGIVARAAERLRIRRTTLVEKMRKYGM
SRREGDEQADD
>Mature_491_residues
MWRETKILLIDDDSVRRRDLAVILNFLGEENLPCGSHDWQQAVGSLSSSREVICVLIGTVNAPGALLGLLKTLSTWDEFL
PVLLMGDNSSVDLPEDQRRRVLSTLEMPPSYSKLLDSLHRAQVYREMYDQARERGRHREPNLFRSLVGTSRAIQHVRQMM
QQVADTDASVLILGESGTGKEVVARNLHYHSKRRDAPFVPVNCGAIPAELLESELFGHEKGAFTGAITSRAGRFELANGG
TLFLDEIGDMPLPMQVKLLRVLQERTFERVGSNKTQSVDVRIIAATHKNLESMIEIGTFREDLYYRLNVFPIEMAPLRER
VEDIPLLMNELISRMEHEKRGSIRFNSAAIMSLCRHGWPGNVRELANLVERMAIMHPYGVIGVVELPKKFRYVDDEDEQM
VDSLRSDLEERVAINGHTPDFTANAMLPPEGLDLKDYLGGLEQGLIQQALDDANGIVARAAERLRIRRTTLVEKMRKYGM
SRREGDEQADD

Specific function: Member of the two-component regulatory system ntrB/ntrC involved in the activation of nitrogen assimilatory genes such as glnA. NtrC is phosphorylated by ntrB and interacts with sigma-54 [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI87082117, Length=343, Percent_Identity=46.064139941691, Blast_Score=280, Evalue=2e-76,
Organism=Escherichia coli, GI1788550, Length=483, Percent_Identity=37.4741200828157, Blast_Score=268, Evalue=8e-73,
Organism=Escherichia coli, GI1789087, Length=344, Percent_Identity=44.4767441860465, Blast_Score=262, Evalue=3e-71,
Organism=Escherichia coli, GI1790437, Length=326, Percent_Identity=45.7055214723926, Blast_Score=259, Evalue=2e-70,
Organism=Escherichia coli, GI1790299, Length=484, Percent_Identity=37.1900826446281, Blast_Score=251, Evalue=7e-68,
Organism=Escherichia coli, GI1788905, Length=273, Percent_Identity=45.4212454212454, Blast_Score=244, Evalue=6e-66,
Organism=Escherichia coli, GI1789233, Length=348, Percent_Identity=41.0919540229885, Blast_Score=234, Evalue=8e-63,
Organism=Escherichia coli, GI1786524, Length=381, Percent_Identity=38.8451443569554, Blast_Score=217, Evalue=2e-57,
Organism=Escherichia coli, GI87082152, Length=231, Percent_Identity=45.8874458874459, Blast_Score=207, Evalue=1e-54,
Organism=Escherichia coli, GI87081872, Length=323, Percent_Identity=39.3188854489164, Blast_Score=204, Evalue=1e-53,
Organism=Escherichia coli, GI1787583, Length=347, Percent_Identity=35.7348703170029, Blast_Score=191, Evalue=9e-50,
Organism=Escherichia coli, GI1789828, Length=240, Percent_Identity=37.5, Blast_Score=150, Evalue=2e-37,
Organism=Escherichia coli, GI87081858, Length=320, Percent_Identity=28.4375, Blast_Score=135, Evalue=4e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR010114
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 55498; Mature: 55498

Theoretical pI: Translated: 5.68; Mature: 5.68

Prosite motif: PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWRETKILLIDDDSVRRRDLAVILNFLGEENLPCGSHDWQQAVGSLSSSREVICVLIGTV
CCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCEEEEEEECC
NAPGALLGLLKTLSTWDEFLPVLLMGDNSSVDLPEDQRRRVLSTLEMPPSYSKLLDSLHR
CCCHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHH
AQVYREMYDQARERGRHREPNLFRSLVGTSRAIQHVRQMMQQVADTDASVLILGESGTGK
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCH
EVVARNLHYHSKRRDAPFVPVNCGAIPAELLESELFGHEKGAFTGAITSRAGRFELANGG
HHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHCCCCCCCHHHHHCCCCCEEECCCC
TLFLDEIGDMPLPMQVKLLRVLQERTFERVGSNKTQSVDVRIIAATHKNLESMIEIGTFR
EEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEHHHHHHHHHHHHHHHH
EDLYYRLNVFPIEMAPLRERVEDIPLLMNELISRMEHEKRGSIRFNSAAIMSLCRHGWPG
HHHEEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECHHHHHHHHHCCCCC
NVRELANLVERMAIMHPYGVIGVVELPKKFRYVDDEDEQMVDSLRSDLEERVAINGHTPD
CHHHHHHHHHHHHHHCCCCCEEHHHCCHHHCCCCCCHHHHHHHHHHHHHHHHEECCCCCC
FTANAMLPPEGLDLKDYLGGLEQGLIQQALDDANGIVARAAERLRIRRTTLVEKMRKYGM
CCCCCCCCCCCCCHHHHHCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCC
SRREGDEQADD
CCCCCCCCCCC
>Mature Secondary Structure
MWRETKILLIDDDSVRRRDLAVILNFLGEENLPCGSHDWQQAVGSLSSSREVICVLIGTV
CCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCEEEEEEECC
NAPGALLGLLKTLSTWDEFLPVLLMGDNSSVDLPEDQRRRVLSTLEMPPSYSKLLDSLHR
CCCHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHH
AQVYREMYDQARERGRHREPNLFRSLVGTSRAIQHVRQMMQQVADTDASVLILGESGTGK
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCH
EVVARNLHYHSKRRDAPFVPVNCGAIPAELLESELFGHEKGAFTGAITSRAGRFELANGG
HHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHCCCCCCCHHHHHCCCCCEEECCCC
TLFLDEIGDMPLPMQVKLLRVLQERTFERVGSNKTQSVDVRIIAATHKNLESMIEIGTFR
EEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEHHHHHHHHHHHHHHHH
EDLYYRLNVFPIEMAPLRERVEDIPLLMNELISRMEHEKRGSIRFNSAAIMSLCRHGWPG
HHHEEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECHHHHHHHHHCCCCC
NVRELANLVERMAIMHPYGVIGVVELPKKFRYVDDEDEQMVDSLRSDLEERVAINGHTPD
CHHHHHHHHHHHHHHCCCCCEEHHHCCHHHCCCCCCHHHHHHHHHHHHHHHHEECCCCCC
FTANAMLPPEGLDLKDYLGGLEQGLIQQALDDANGIVARAAERLRIRRTTLVEKMRKYGM
CCCCCCCCCCCCCHHHHHCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCC
SRREGDEQADD
CCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1661370 [H]