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The map label for this gene is rfbC [C]

Identifier: 77457739

GI number: 77457739

Start: 1699477

End: 1700037

Strand: Direct

Name: rfbC [C]

Synonym: Pfl01_1512

Alternate gene names: 77457739

Gene position: 1699477-1700037 (Clockwise)

Preceding gene: 77457738

Following gene: 77457740

Centisome position: 26.4

GC content: 61.14

Gene sequence:

>561_bases
GTGAGCGAGTTTTCCTTGAAACCGTTGCCGCTGGCCGGGTTGTTCAGCGTCCAGCACAAGCGCTTCGAAGATCAGCGCGG
GCACTTCGCCCGTCTGTTCTGCGAAGGCAGCCTGAAAGCGTTCGGCAGTGAATTTCACATCCGCCAGATCAACCATTCCT
GCACCCGCGAGAAGGGCAGCGTGCGCGGTCTGCATTACCAGAACGCCAATGCGCCGGAAGCCAAGTTGATCACCTGCCTG
CGAGGTGAAGTGTGGGACGTAGCGGTAGACCTGCGCCCGGACTCGGAAACCTTCCTGCACTGGCACGCCGAGCACCTGAA
GGCCGGTGACGGTCGCAGCCTGTTGATTCCGGCCGGCTTCGCCCACGGTTTCCAGACCCTCACTGAAGACGCCGAACTGC
TTTACCTGCACAGCGCCGATTACGCGCCGGAGCACGAGGGCGGTCTGTCGGTGAACGATCCACGGCTGGCGATCGCCTGG
CCGTTGCCTGTCAATAATTTGTCAGCGCGTGATTCCAGCCATCCCGCGCTCGATCAACACTTTGCTGGAGTGCGTCTATG
A

Upstream 100 bases:

>100_bases
AATGCCTGACCCAGACCCTCGACTGGCACCTGGCGTGGCAGAACGGCGACGACATGCGCACCGTGACCCTCGGCCAACTG
AACCTGTACCGGGGCGCGCT

Downstream 100 bases:

>100_bases
ACTGCCGTGGGTGCGCCGCACCGCTGAGCTTGCCGCTGATCGACCTCGGCACCTCGCCACCGTCCAACGCCTACGTGCAC
GTCGATCGGCTGGAGCAGGC

Product: dTDP-4-dehydrorhamnose 3,5-epimerase

Products: NA

Alternate protein names: Thymidine diphospho-4-keto-rhamnose 3,5-epimerase; dTDP-4-keto-6-deoxyglucose 3,5-epimerase; dTDP-6-deoxy-D-xylo-4-hexulose 3,5-epimerase; dTDP-L-rhamnose synthase [H]

Number of amino acids: Translated: 186; Mature: 185

Protein sequence:

>186_residues
MSEFSLKPLPLAGLFSVQHKRFEDQRGHFARLFCEGSLKAFGSEFHIRQINHSCTREKGSVRGLHYQNANAPEAKLITCL
RGEVWDVAVDLRPDSETFLHWHAEHLKAGDGRSLLIPAGFAHGFQTLTEDAELLYLHSADYAPEHEGGLSVNDPRLAIAW
PLPVNNLSARDSSHPALDQHFAGVRL

Sequences:

>Translated_186_residues
MSEFSLKPLPLAGLFSVQHKRFEDQRGHFARLFCEGSLKAFGSEFHIRQINHSCTREKGSVRGLHYQNANAPEAKLITCL
RGEVWDVAVDLRPDSETFLHWHAEHLKAGDGRSLLIPAGFAHGFQTLTEDAELLYLHSADYAPEHEGGLSVNDPRLAIAW
PLPVNNLSARDSSHPALDQHFAGVRL
>Mature_185_residues
SEFSLKPLPLAGLFSVQHKRFEDQRGHFARLFCEGSLKAFGSEFHIRQINHSCTREKGSVRGLHYQNANAPEAKLITCLR
GEVWDVAVDLRPDSETFLHWHAEHLKAGDGRSLLIPAGFAHGFQTLTEDAELLYLHSADYAPEHEGGLSVNDPRLAIAWP
LPVNNLSARDSSHPALDQHFAGVRL

Specific function: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose [H]

COG id: COG1898

COG function: function code M; dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI1788350, Length=143, Percent_Identity=40.5594405594406, Blast_Score=105, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17550412, Length=172, Percent_Identity=36.046511627907, Blast_Score=99, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR000888
- InterPro:   IPR014710
- ProDom:   PD001462 [H]

Pfam domain/function: PF00908 dTDP_sugar_isom [H]

EC number: =5.1.3.13 [H]

Molecular weight: Translated: 20755; Mature: 20623

Theoretical pI: Translated: 6.70; Mature: 6.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEFSLKPLPLAGLFSVQHKRFEDQRGHFARLFCEGSLKAFGSEFHIRQINHSCTREKGS
CCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCHHHCCCEEEEEECCCHHHCCCCC
VRGLHYQNANAPEAKLITCLRGEVWDVAVDLRPDSETFLHWHAEHLKAGDGRSLLIPAGF
CCEEEECCCCCCHHHHHHHHCCCEEEEEEEECCCCCCEEEEEHHHHCCCCCCEEEEECCH
AHGFQTLTEDAELLYLHSADYAPEHEGGLSVNDPRLAIAWPLPVNNLSARDSSHPALDQH
HHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCHHHH
FAGVRL
CCCCCC
>Mature Secondary Structure 
SEFSLKPLPLAGLFSVQHKRFEDQRGHFARLFCEGSLKAFGSEFHIRQINHSCTREKGS
CCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCHHHCCCEEEEEECCCHHHCCCCC
VRGLHYQNANAPEAKLITCLRGEVWDVAVDLRPDSETFLHWHAEHLKAGDGRSLLIPAGF
CCEEEECCCCCCHHHHHHHHCCCEEEEEEEECCCCCCEEEEEHHHHCCCCCCEEEEECCH
AHGFQTLTEDAELLYLHSADYAPEHEGGLSVNDPRLAIAWPLPVNNLSARDSSHPALDQH
HHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCHHHH
FAGVRL
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]