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The map label for this gene is rfbG [H]

Identifier: 77457738

GI number: 77457738

Start: 1698398

End: 1699480

Strand: Direct

Name: rfbG [H]

Synonym: Pfl01_1511

Alternate gene names: 77457738

Gene position: 1698398-1699480 (Clockwise)

Preceding gene: 77457737

Following gene: 77457739

Centisome position: 26.38

GC content: 66.02

Gene sequence:

>1083_bases
ATGGAAGCAATGGGACTGAGTCCGGAATTCTGGCGCGGCAAGCGGGTTCTGGTCACCGGCCACACCGGTTTCAAGGGCAG
CTGGCTGACCCTGTGGCTGCAAAGCCTCGGCGCGCAAGTCAGCGGTTTTTCCCTCGATCCGTCGACCGAGCCGAGCCTGT
TCGAACTGGCGCGCGTGAGCGAAGGCATCAACGACCAGCGCGGCGACCTGCGTGACCTCGGCGCCTTGCTCGAGATCATC
GCTGACACCGAGCCTGAGATCGTCCTGCACCTGGCGGCCCAGCCGCTGGTGCGTGAAGGTTATCGCGATCCGCTGGGGAC
TTATTCCAGCAACGTCATGGGCACCCTCAATCTGCTCGAAGCGATTCGTCAGGTCGGTTGCGTGCGGGCCTGCGTGCTGG
TGACCACCGACAAGGTCTACGCCAACAAGGAATGGCTGTGGCCGTACCGCGAGGACGAAGCCCTCGGTGGTCACGATCCT
TACAGCAGCAGCAAGGCCTGCTGCGAGTTGCTGGCGCAGTCTTACGCGGCATCGTTCTTCCCGGCCGACAAGTACGCCGA
GCATGGTCTGGCCCTGGCCACCGCGCGCGCCGGCAACGTGTTGGGTGGTGGCGACTTCGCCCCAGAACGGCTGATTCCCG
ATGTACTGAAAGCCTGGTCGGCCGACGAGCCGGTGACCTTGCGTTACCCGCAAGCCGTGCGCCCGTGGCAGCACGCGCTG
GAGCCGCTGGCCGGCTATCTGCAACTGGCCGCCGGGCTCTACGAACAAGGCCCGGAGTACGCCGGCGCGTGGAACTTCGG
TCCGGGCGAGGCGGACATGTGCAGCGTCGGTGAAGTGGTCGAACTGCTCTCCAACCGCTGGCCTCAGGCCCGTGGGCTGC
GCCTCGAAAAGAGCGACCTGCACGAAGCCGGTCTGCTGCGCCTGGACAGCAGCCGCGCCCGTCAGGTGCTCGGCTGGCAA
CCGCGCTGGACGTTGCAGCAATGCCTGACCCAGACCCTCGACTGGCACCTGGCGTGGCAGAACGGCGACGACATGCGCAC
CGTGACCCTCGGCCAACTGAACCTGTACCGGGGCGCGCTGTGA

Upstream 100 bases:

>100_bases
GCGAGTTGATGGCGTACCAGCACGAAGGCTTCTGGCAGCCAATGGACACCTTGCGTGACAAGAACCACCTCGAAGCCTTG
TGGCAGAGCGGGGAGGCCCC

Downstream 100 bases:

>100_bases
GCGAGTTTTCCTTGAAACCGTTGCCGCTGGCCGGGTTGTTCAGCGTCCAGCACAAGCGCTTCGAAGATCAGCGCGGGCAC
TTCGCCCGTCTGTTCTGCGA

Product: NAD-dependent epimerase/dehydratase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 360; Mature: 360

Protein sequence:

>360_residues
MEAMGLSPEFWRGKRVLVTGHTGFKGSWLTLWLQSLGAQVSGFSLDPSTEPSLFELARVSEGINDQRGDLRDLGALLEII
ADTEPEIVLHLAAQPLVREGYRDPLGTYSSNVMGTLNLLEAIRQVGCVRACVLVTTDKVYANKEWLWPYREDEALGGHDP
YSSSKACCELLAQSYAASFFPADKYAEHGLALATARAGNVLGGGDFAPERLIPDVLKAWSADEPVTLRYPQAVRPWQHAL
EPLAGYLQLAAGLYEQGPEYAGAWNFGPGEADMCSVGEVVELLSNRWPQARGLRLEKSDLHEAGLLRLDSSRARQVLGWQ
PRWTLQQCLTQTLDWHLAWQNGDDMRTVTLGQLNLYRGAL

Sequences:

>Translated_360_residues
MEAMGLSPEFWRGKRVLVTGHTGFKGSWLTLWLQSLGAQVSGFSLDPSTEPSLFELARVSEGINDQRGDLRDLGALLEII
ADTEPEIVLHLAAQPLVREGYRDPLGTYSSNVMGTLNLLEAIRQVGCVRACVLVTTDKVYANKEWLWPYREDEALGGHDP
YSSSKACCELLAQSYAASFFPADKYAEHGLALATARAGNVLGGGDFAPERLIPDVLKAWSADEPVTLRYPQAVRPWQHAL
EPLAGYLQLAAGLYEQGPEYAGAWNFGPGEADMCSVGEVVELLSNRWPQARGLRLEKSDLHEAGLLRLDSSRARQVLGWQ
PRWTLQQCLTQTLDWHLAWQNGDDMRTVTLGQLNLYRGAL
>Mature_360_residues
MEAMGLSPEFWRGKRVLVTGHTGFKGSWLTLWLQSLGAQVSGFSLDPSTEPSLFELARVSEGINDQRGDLRDLGALLEII
ADTEPEIVLHLAAQPLVREGYRDPLGTYSSNVMGTLNLLEAIRQVGCVRACVLVTTDKVYANKEWLWPYREDEALGGHDP
YSSSKACCELLAQSYAASFFPADKYAEHGLALATARAGNVLGGGDFAPERLIPDVLKAWSADEPVTLRYPQAVRPWQHAL
EPLAGYLQLAAGLYEQGPEYAGAWNFGPGEADMCSVGEVVELLSNRWPQARGLRLEKSDLHEAGLLRLDSSRARQVLGWQ
PRWTLQQCLTQTLDWHLAWQNGDDMRTVTLGQLNLYRGAL

Specific function: DTDP-L-RHAMNOSE BIOSYNTHESIS WITHIN THE O ANTIGEN BIOSYNTHESIS PATHWAY OF LIPOPOLYSACCHARIDE BIOSYNTHESIS. [C]

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI48994969, Length=343, Percent_Identity=25.3644314868805, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1788353, Length=352, Percent_Identity=26.4204545454545, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI1786974, Length=347, Percent_Identity=25.3602305475504, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17568069, Length=278, Percent_Identity=26.6187050359712, Blast_Score=78, Evalue=6e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013445
- InterPro:   IPR001509
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =4.2.1.45 [H]

Molecular weight: Translated: 39794; Mature: 39794

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEAMGLSPEFWRGKRVLVTGHTGFKGSWLTLWLQSLGAQVSGFSLDPSTEPSLFELARVS
CCCCCCCHHHHCCCEEEEECCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHH
EGINDQRGDLRDLGALLEIIADTEPEIVLHLAAQPLVREGYRDPLGTYSSNVMGTLNLLE
CCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEHHCHHHHHCCCCCCCCHHHHHHHHHHHHH
AIRQVGCVRACVLVTTDKVYANKEWLWPYREDEALGGHDPYSSSKACCELLAQSYAASFF
HHHHHHHHHHHHHEEECHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCC
PADKYAEHGLALATARAGNVLGGGDFAPERLIPDVLKAWSADEPVTLRYPQAVRPWQHAL
CCHHHHHCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHH
EPLAGYLQLAAGLYEQGPEYAGAWNFGPGEADMCSVGEVVELLSNRWPQARGLRLEKSDL
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHCCCCCHHHH
HEAGLLRLDSSRARQVLGWQPRWTLQQCLTQTLDWHLAWQNGDDMRTVTLGQLNLYRGAL
HHHHHEEECCHHHHHHHCCCCCHHHHHHHHHHHCEEEEECCCCCEEEEEECCHHHHHCCC
>Mature Secondary Structure
MEAMGLSPEFWRGKRVLVTGHTGFKGSWLTLWLQSLGAQVSGFSLDPSTEPSLFELARVS
CCCCCCCHHHHCCCEEEEECCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHH
EGINDQRGDLRDLGALLEIIADTEPEIVLHLAAQPLVREGYRDPLGTYSSNVMGTLNLLE
CCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEHHCHHHHHCCCCCCCCHHHHHHHHHHHHH
AIRQVGCVRACVLVTTDKVYANKEWLWPYREDEALGGHDPYSSSKACCELLAQSYAASFF
HHHHHHHHHHHHHEEECHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCC
PADKYAEHGLALATARAGNVLGGGDFAPERLIPDVLKAWSADEPVTLRYPQAVRPWQHAL
CCHHHHHCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHH
EPLAGYLQLAAGLYEQGPEYAGAWNFGPGEADMCSVGEVVELLSNRWPQARGLRLEKSDL
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHCCCCCHHHH
HEAGLLRLDSSRARQVLGWQPRWTLQQCLTQTLDWHLAWQNGDDMRTVTLGQLNLYRGAL
HHHHHEEECCHHHHHHHCCCCCHHHHHHHHHHHCEEEEECCCCCEEEEEECCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1710759; 11677609 [H]