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The map label for this gene is mprF [H]

Identifier: 77457421

GI number: 77457421

Start: 1362787

End: 1365426

Strand: Reverse

Name: mprF [H]

Synonym: Pfl01_1194

Alternate gene names: 77457421

Gene position: 1365426-1362787 (Counterclockwise)

Preceding gene: 77457423

Following gene: 77457420

Centisome position: 21.21

GC content: 64.17

Gene sequence:

>2640_bases
ATGCGCGCCAACTCGTCTGATTCACAAGACACCATCACAGCGAACCCACCGATCAAGCCTGAGCGTCTGCGCCTGCTGGA
TCGGATCAGCAAATACCGGCAACCGATCGGTCTGGCGGTCACTTTGCTGCTGTTCGCCATCGCGCTGATTGCCTGTCGCC
ATCTGCTCAGCGAACTCGATCTCGACGCCCTGCACGACTCGATACTCGACGTGCCGAAACCGGCCCTGCTCGGTGCCCTC
GGTGCGACGGTCGTCGGCTTCATTATCCTGCTCGGCTATGAATGGTCGGCCAGTCGATATGCCCGCGTGACGCTGGCGCC
GAAAGTGCTGGCACTGGGCGGTTTCACCGCGTTTGCCATCGGCAACGCCATCGGCCTGTCGATGCTGTCCGGTGGCTCGG
TGCGTTACCGTTTATATGCACGACATGGCCTGGGCGCTTCCGAAGTCGCGCACATGACCCTGTTCGCCAGCCTGTCGCTG
GGCTGCGCCCTGCCGCCGCTGGCTGCGCTTGCGACCCTGAGCAACCTGCCCGCCGCGTCACAGGCCCTGGGGCTGTCCGA
GACCTTGTTGGGCACGATTGCCGGCGTGGTGCTGCTGCTCGGCGCGATCCTGGCCATCGGCATCTATCGCCGTCGCCTGC
CGGAACAACCCTATCCGGACAACCTGTTGGTCCGGGCCGGTCGCCGCACCCTGCGCCTGCCGGGTCGCCGCCTGACCTTC
CTGCAACTGGTCATCACCGCCCTCGACGTCGCCGCTGCTGCGACCGTCCTTTATCTGCTGCTGCCGGAAGCGCCACCCTT
CGGTGCATTCCTGCTGGTTTATCTGCTGGCGCTGGCGGCCGGCGTGCTCAGTCACGTTCCGGGTGGCGTGGGCGTCTTTG
AAGCAATTCTGCTGGCCGCGTTCGCCGACAAGCTCGGCGCCGCGCCACTGGCTGCTGCCCTGCTCCTGTATCGCCTGATC
TATGTGGTGCTGCCGTTGCTGGTGGCCTGCGTGCTGCTGCTGATCAATGAAGGCCAGCGCCTGTTTCAGTCGCAGACCAT
GCGTGCGGCTTCCGGTCTGGCGGCACCGATTCTCGCGGTGCTGGTGTTCCTGTCCGGCGTGGTGCTGCTGTTTTCCGGGG
CGACGCCAGAGATCGACACCCGTCTTGAACACATCGGTTTTCTGATTCCCCACCGTCTGGTCGATGCTTCGCACTTTGGC
GCCAGCCTGATCGGCGTGCTGTGCCTGATGCTCGCTCAAGGCCTGCGTCGCCGGTTGTCGGCGGCGTGGATGCTGACCAC
CATTCTGTTGCTGGTGGGCGCCCTGCTCTCGCTGCTCAAGGGTTTCGACTGGGAAGAAGCGACCCTGATGACCCTCACCG
CCGCGCTGCTGGGGGTGTTCCGCCGTTCGTTCTACCGCCCGAGCCGCCTCACCGAACTGCCGTTCTCGCCGCTGTATCTG
GTGGCCAGCCTGTGCGTACTCGGTGCCTCGACCTGGCTTTTGCTGTTCGCTTATCAGGACGTTCCTTACAGCCATCAACT
GTGGTGGCAGTTCACTCTCGACGCCGACGCCCCGCGCGGCCTGCGCTCGCTGCTCGGCGCCGCTGTGTTGCTGCTGGTGA
TCGCTCTGACCTGGCTGCTGCGCACCGCCCGCCCGGTGATTCACCTGCCGACACCGGACGAACTGGAACGCGCCTCGAAA
ATTCTGATGGCTTCCTCGCAACCGGACGGCGGCCTGGCCCTGACCGGTGACAAGGCGCTGCTGTTTCATCCCAACGACGA
AGCCTTCCTGATGTACGCCCGTCGCGGCCGCAGTCTGGTGGCCCTGTACGACCCGATCGGCCCCGGCCAGCAACGGGCCG
AGATGATCTGGCAGTTCCGCGACCTGTGCGACATCCATCACGCCCGCCCGGTGTTCTATCAGGTGCGCGCCGAGAACCTG
CCGTACTACATGGACATCGGCCTGACCGCGATCAAGCTGGGCGAGGAAGCCCGGGTCGATCTGCATCGCTTTGACCTGGA
AGCCAAGGGCAAGGAGATGAAGGACCTGCGCTACACCTGGAACCGTGGCACCCGCGACGGCCTGTCGCTGGAAATCCATG
AGCCGGGCCAGGCGCCGATGGATGAGCTCAAGGTGATTTCCGACGCCTGGCTGACCGGCAAGAACGTGCGCGAGAAAGGC
TTCTCCCTCGGCCGCTTCAGCGACGATTACCTGAAGCATTTCCGCATCGCGGTGATTCGCTTCGAAGGGCGTCCGGTGGC
GTTCGCCAACCTGCTCGAGACCTACAGCCATGACCTGGCCAGTCTCGACCTGATGCGCGCGCACCCGGACGCCCCCAAAC
TGACCATGGAATTCATGATGGTCGGTCTGATTCAACACTATAAGAGTCACGGATACGCGCGCTTCAGCCTGGGCATGGTG
CCGCTGTCGGGGTTGCAACCCCGGCGCGGGGCACCGCTGACCCAGCGTCTGGGTTCGATGGTTTTCCGCCGTGGTGAGCA
GCTGTACAACTTCCAAGGCTTGCGCCGCTTCAAAGACAAGTTCCAGCCTGACTGGGAACCCCGTTATATGGCAGTGCCCG
CCGGACTCGATCCGCTGGTGGCACTGGCCGATACTGCTGCCCTGATCGCGGGCGGCTTGACTGGATTGGTGAAACGCTGA

Upstream 100 bases:

>100_bases
CCGGTGAGAGGCGTAGTATTTTGTGATTATTTTTTTCTACAGGGATTGGTAACTTGGCTGGATACCTCCATCCTGTCGCG
CACAATCCAAGAGGTGATTG

Downstream 100 bases:

>100_bases
TGATTCAACGCTCCCTGAAGTACATCCTGGTCGCACTGCTGGTGCTGGCCGCGATTGCCGGTGGCGGTTTCTGGTACCTC
AAACGCCCGGCACCGGAACC

Product: hypothetical protein

Products: NA

Alternate protein names: Lysylphosphatidylglycerol synthase; LPG synthase; Multiple peptide resistance factor [H]

Number of amino acids: Translated: 879; Mature: 879

Protein sequence:

>879_residues
MRANSSDSQDTITANPPIKPERLRLLDRISKYRQPIGLAVTLLLFAIALIACRHLLSELDLDALHDSILDVPKPALLGAL
GATVVGFIILLGYEWSASRYARVTLAPKVLALGGFTAFAIGNAIGLSMLSGGSVRYRLYARHGLGASEVAHMTLFASLSL
GCALPPLAALATLSNLPAASQALGLSETLLGTIAGVVLLLGAILAIGIYRRRLPEQPYPDNLLVRAGRRTLRLPGRRLTF
LQLVITALDVAAAATVLYLLLPEAPPFGAFLLVYLLALAAGVLSHVPGGVGVFEAILLAAFADKLGAAPLAAALLLYRLI
YVVLPLLVACVLLLINEGQRLFQSQTMRAASGLAAPILAVLVFLSGVVLLFSGATPEIDTRLEHIGFLIPHRLVDASHFG
ASLIGVLCLMLAQGLRRRLSAAWMLTTILLLVGALLSLLKGFDWEEATLMTLTAALLGVFRRSFYRPSRLTELPFSPLYL
VASLCVLGASTWLLLFAYQDVPYSHQLWWQFTLDADAPRGLRSLLGAAVLLLVIALTWLLRTARPVIHLPTPDELERASK
ILMASSQPDGGLALTGDKALLFHPNDEAFLMYARRGRSLVALYDPIGPGQQRAEMIWQFRDLCDIHHARPVFYQVRAENL
PYYMDIGLTAIKLGEEARVDLHRFDLEAKGKEMKDLRYTWNRGTRDGLSLEIHEPGQAPMDELKVISDAWLTGKNVREKG
FSLGRFSDDYLKHFRIAVIRFEGRPVAFANLLETYSHDLASLDLMRAHPDAPKLTMEFMMVGLIQHYKSHGYARFSLGMV
PLSGLQPRRGAPLTQRLGSMVFRRGEQLYNFQGLRRFKDKFQPDWEPRYMAVPAGLDPLVALADTAALIAGGLTGLVKR

Sequences:

>Translated_879_residues
MRANSSDSQDTITANPPIKPERLRLLDRISKYRQPIGLAVTLLLFAIALIACRHLLSELDLDALHDSILDVPKPALLGAL
GATVVGFIILLGYEWSASRYARVTLAPKVLALGGFTAFAIGNAIGLSMLSGGSVRYRLYARHGLGASEVAHMTLFASLSL
GCALPPLAALATLSNLPAASQALGLSETLLGTIAGVVLLLGAILAIGIYRRRLPEQPYPDNLLVRAGRRTLRLPGRRLTF
LQLVITALDVAAAATVLYLLLPEAPPFGAFLLVYLLALAAGVLSHVPGGVGVFEAILLAAFADKLGAAPLAAALLLYRLI
YVVLPLLVACVLLLINEGQRLFQSQTMRAASGLAAPILAVLVFLSGVVLLFSGATPEIDTRLEHIGFLIPHRLVDASHFG
ASLIGVLCLMLAQGLRRRLSAAWMLTTILLLVGALLSLLKGFDWEEATLMTLTAALLGVFRRSFYRPSRLTELPFSPLYL
VASLCVLGASTWLLLFAYQDVPYSHQLWWQFTLDADAPRGLRSLLGAAVLLLVIALTWLLRTARPVIHLPTPDELERASK
ILMASSQPDGGLALTGDKALLFHPNDEAFLMYARRGRSLVALYDPIGPGQQRAEMIWQFRDLCDIHHARPVFYQVRAENL
PYYMDIGLTAIKLGEEARVDLHRFDLEAKGKEMKDLRYTWNRGTRDGLSLEIHEPGQAPMDELKVISDAWLTGKNVREKG
FSLGRFSDDYLKHFRIAVIRFEGRPVAFANLLETYSHDLASLDLMRAHPDAPKLTMEFMMVGLIQHYKSHGYARFSLGMV
PLSGLQPRRGAPLTQRLGSMVFRRGEQLYNFQGLRRFKDKFQPDWEPRYMAVPAGLDPLVALADTAALIAGGLTGLVKR
>Mature_879_residues
MRANSSDSQDTITANPPIKPERLRLLDRISKYRQPIGLAVTLLLFAIALIACRHLLSELDLDALHDSILDVPKPALLGAL
GATVVGFIILLGYEWSASRYARVTLAPKVLALGGFTAFAIGNAIGLSMLSGGSVRYRLYARHGLGASEVAHMTLFASLSL
GCALPPLAALATLSNLPAASQALGLSETLLGTIAGVVLLLGAILAIGIYRRRLPEQPYPDNLLVRAGRRTLRLPGRRLTF
LQLVITALDVAAAATVLYLLLPEAPPFGAFLLVYLLALAAGVLSHVPGGVGVFEAILLAAFADKLGAAPLAAALLLYRLI
YVVLPLLVACVLLLINEGQRLFQSQTMRAASGLAAPILAVLVFLSGVVLLFSGATPEIDTRLEHIGFLIPHRLVDASHFG
ASLIGVLCLMLAQGLRRRLSAAWMLTTILLLVGALLSLLKGFDWEEATLMTLTAALLGVFRRSFYRPSRLTELPFSPLYL
VASLCVLGASTWLLLFAYQDVPYSHQLWWQFTLDADAPRGLRSLLGAAVLLLVIALTWLLRTARPVIHLPTPDELERASK
ILMASSQPDGGLALTGDKALLFHPNDEAFLMYARRGRSLVALYDPIGPGQQRAEMIWQFRDLCDIHHARPVFYQVRAENL
PYYMDIGLTAIKLGEEARVDLHRFDLEAKGKEMKDLRYTWNRGTRDGLSLEIHEPGQAPMDELKVISDAWLTGKNVREKG
FSLGRFSDDYLKHFRIAVIRFEGRPVAFANLLETYSHDLASLDLMRAHPDAPKLTMEFMMVGLIQHYKSHGYARFSLGMV
PLSGLQPRRGAPLTQRLGSMVFRRGEQLYNFQGLRRFKDKFQPDWEPRYMAVPAGLDPLVALADTAALIAGGLTGLVKR

Specific function: Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes

COG id: COG2898

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the LPG synthase family [H]

Homologues:

Organism=Escherichia coli, GI1787006, Length=306, Percent_Identity=26.1437908496732, Blast_Score=84, Evalue=5e-17,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016181
- InterPro:   IPR022791 [H]

Pfam domain/function: PF03706 UPF0104 [H]

EC number: =2.3.2.3 [H]

Molecular weight: Translated: 96231; Mature: 96231

Theoretical pI: Translated: 9.65; Mature: 9.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRANSSDSQDTITANPPIKPERLRLLDRISKYRQPIGLAVTLLLFAIALIACRHLLSELD
CCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCC
LDALHDSILDVPKPALLGALGATVVGFIILLGYEWSASRYARVTLAPKVLALGGFTAFAI
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCHHHHHCCHHHHHH
GNAIGLSMLSGGSVRYRLYARHGLGASEVAHMTLFASLSLGCALPPLAALATLSNLPAAS
HHHHHHHHHCCCCEEEEEEEECCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHH
QALGLSETLLGTIAGVVLLLGAILAIGIYRRRLPEQPYPDNLLVRAGRRTLRLPGRRLTF
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCHHCCCCCCHHHH
LQLVITALDVAAAATVLYLLLPEAPPFGAFLLVYLLALAAGVLSHVPGGVGVFEAILLAA
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
FADKLGAAPLAAALLLYRLIYVVLPLLVACVLLLINEGQRLFQSQTMRAASGLAAPILAV
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCHHHHHHHH
LVFLSGVVLLFSGATPEIDTRLEHIGFLIPHRLVDASHFGASLIGVLCLMLAQGLRRRLS
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAWMLTTILLLVGALLSLLKGFDWEEATLMTLTAALLGVFRRSFYRPSRLTELPFSPLYL
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHH
VASLCVLGASTWLLLFAYQDVPYSHQLWWQFTLDADAPRGLRSLLGAAVLLLVIALTWLL
HHHHHHHHHHHHHHHHEECCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHH
RTARPVIHLPTPDELERASKILMASSQPDGGLALTGDKALLFHPNDEAFLMYARRGRSLV
HCCCCEEECCCCHHHHHHHHHHHCCCCCCCCEEEECCEEEEECCCCCEEEEEEECCCEEE
ALYDPIGPGQQRAEMIWQFRDLCDIHHARPVFYQVRAENLPYYMDIGLTAIKLGEEARVD
EEECCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEECCCEEEECCCHHHHH
LHRFDLEAKGKEMKDLRYTWNRGTRDGLSLEIHEPGQAPMDELKVISDAWLTGKNVREKG
HHHHCCCCCCCHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCHHHCC
FSLGRFSDDYLKHFRIAVIRFEGRPVAFANLLETYSHDLASLDLMRAHPDAPKLTMEFMM
CCCCCCCHHHHHHHEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
VGLIQHYKSHGYARFSLGMVPLSGLQPRRGAPLTQRLGSMVFRRGEQLYNFQGLRRFKDK
HHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHH
FQPDWEPRYMAVPAGLDPLVALADTAALIAGGLTGLVKR
CCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRANSSDSQDTITANPPIKPERLRLLDRISKYRQPIGLAVTLLLFAIALIACRHLLSELD
CCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCC
LDALHDSILDVPKPALLGALGATVVGFIILLGYEWSASRYARVTLAPKVLALGGFTAFAI
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCHHHHHCCHHHHHH
GNAIGLSMLSGGSVRYRLYARHGLGASEVAHMTLFASLSLGCALPPLAALATLSNLPAAS
HHHHHHHHHCCCCEEEEEEEECCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHH
QALGLSETLLGTIAGVVLLLGAILAIGIYRRRLPEQPYPDNLLVRAGRRTLRLPGRRLTF
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCHHCCCCCCHHHH
LQLVITALDVAAAATVLYLLLPEAPPFGAFLLVYLLALAAGVLSHVPGGVGVFEAILLAA
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
FADKLGAAPLAAALLLYRLIYVVLPLLVACVLLLINEGQRLFQSQTMRAASGLAAPILAV
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCHHHHHHHH
LVFLSGVVLLFSGATPEIDTRLEHIGFLIPHRLVDASHFGASLIGVLCLMLAQGLRRRLS
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAWMLTTILLLVGALLSLLKGFDWEEATLMTLTAALLGVFRRSFYRPSRLTELPFSPLYL
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHH
VASLCVLGASTWLLLFAYQDVPYSHQLWWQFTLDADAPRGLRSLLGAAVLLLVIALTWLL
HHHHHHHHHHHHHHHHEECCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHH
RTARPVIHLPTPDELERASKILMASSQPDGGLALTGDKALLFHPNDEAFLMYARRGRSLV
HCCCCEEECCCCHHHHHHHHHHHCCCCCCCCEEEECCEEEEECCCCCEEEEEEECCCEEE
ALYDPIGPGQQRAEMIWQFRDLCDIHHARPVFYQVRAENLPYYMDIGLTAIKLGEEARVD
EEECCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEECCCEEEECCCHHHHH
LHRFDLEAKGKEMKDLRYTWNRGTRDGLSLEIHEPGQAPMDELKVISDAWLTGKNVREKG
HHHHCCCCCCCHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCHHHCC
FSLGRFSDDYLKHFRIAVIRFEGRPVAFANLLETYSHDLASLDLMRAHPDAPKLTMEFMM
CCCCCCCHHHHHHHEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
VGLIQHYKSHGYARFSLGMVPLSGLQPRRGAPLTQRLGSMVFRRGEQLYNFQGLRRFKDK
HHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHH
FQPDWEPRYMAVPAGLDPLVALADTAALIAGGLTGLVKR
CCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA