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The map label for this gene is nagA [H]

Identifier: 77457233

GI number: 77457233

Start: 1172231

End: 1173337

Strand: Reverse

Name: nagA [H]

Synonym: Pfl01_1006

Alternate gene names: 77457233

Gene position: 1173337-1172231 (Counterclockwise)

Preceding gene: 77457234

Following gene: 77457232

Centisome position: 18.22

GC content: 64.41

Gene sequence:

>1107_bases
ATGTCCGAAGACAACATCCTCACCGCTGACGGCTGGATTCGCGGCCGGCTGATCCACGAACACGGCAGAGTCGTGTCGAT
CGAAGGCGAGCCTTGCGATCCGGCGACCAATGACTTGCCGTATCTGCTGCCGGGTTTCATCGACCTGCACGTCCACGGCG
GTGGCGGCAAGGACATCATGGAAGGCGCCAGCGCGTTCGAGACCATCACCAAGACCCACGTGCGCTTCGGCACCACCTCG
CTGCTGGCCACCACGATGACCGCGCCGAGAGCCGAGATTGCCAGCGTGCTCAAGGAGGTCGGCGAGTTCTGCGAGCAGCG
TCCGAAAGGTGCTGCCCGAGTCCTCGGCGTGCACCTCGAAGGCCCGTACATCAATCCCGGCAAACTCGGCGCCCAGCCGA
ACTTCGCCCACACCGCGTTGATGGCCGAAGTTGAAGACTATCTGGCGCTGGCGCCGATCCGGGTGATCACCATCGCCCCG
GAAATCGCCGGCCATGACGGATTGATTCGTGAACTGAGCCGCCGTGGCATCCGCATGCAGATCGGTCATACCCTCGGCAG
TTACGAGGAAGGCGTCGCCGCCCTCGAAGCCGGCGCCACCAGTTTCACCCACTTGTACAACGCCATGAGCCCGCTGCATC
ACCGCGAGCCGGGTATCGTCGGTGCGGCGCTGGCCCACGCCAAATTCGCCGAACTGATTCCGGACTTGCTGCACGTGCAC
CCCGGCGCGATCCGCGTGGCTCTGCGCTCGATTCCGTGCCTGTACTGCGTCACCGATTCGACCGCCGCCGCCGGCATGCC
CGACGGCGAATACAAGCTCGGCAGCCACACCGTCACCAAATGCCTGGGCGGCGTGCGCCTGCCCGATGGCACCCTGGCCG
GCAGCACCCTGACCATGGATCAGGCCCTGCGCAATCTGGTGAAGATCGGTTTGCCGATCGCCGAAGCCTCGCAACGTCTT
TCGCAATTCCCCGCCGACTACCTCGGCATCACCGAACGCGGGCGCCTTGCACCTGGCGCCTGGGCCGACTGCGTGCGGCT
GGATCGCTCACTCACACTGACCGCCGTCATGGTCGAAGGAGAAGACATTGACTTCAAAAATGCTTGA

Upstream 100 bases:

>100_bases
GCCGATCGAAGTCACCGACACCTATTGCCGCAACGACTACTACGACTTTGTTGCAGAGCTTCGCCGCTGATCAGCAGCCA
GGCCAAACGAGAGAAGCGAA

Downstream 100 bases:

>100_bases
GGAGGCGCTGTCCTCGTTCGAGGCCGTGCAAGCCCAACTGCAACAGCTCGACCCGCCAATGATCGAGATCGCCGGACGCC
TGCGCCGTCAGCCACCGCAA

Product: N-acetylglucosamine 6-phosphate deacetylase

Products: NA

Alternate protein names: GlcNAc 6-P deacetylase [H]

Number of amino acids: Translated: 368; Mature: 367

Protein sequence:

>368_residues
MSEDNILTADGWIRGRLIHEHGRVVSIEGEPCDPATNDLPYLLPGFIDLHVHGGGGKDIMEGASAFETITKTHVRFGTTS
LLATTMTAPRAEIASVLKEVGEFCEQRPKGAARVLGVHLEGPYINPGKLGAQPNFAHTALMAEVEDYLALAPIRVITIAP
EIAGHDGLIRELSRRGIRMQIGHTLGSYEEGVAALEAGATSFTHLYNAMSPLHHREPGIVGAALAHAKFAELIPDLLHVH
PGAIRVALRSIPCLYCVTDSTAAAGMPDGEYKLGSHTVTKCLGGVRLPDGTLAGSTLTMDQALRNLVKIGLPIAEASQRL
SQFPADYLGITERGRLAPGAWADCVRLDRSLTLTAVMVEGEDIDFKNA

Sequences:

>Translated_368_residues
MSEDNILTADGWIRGRLIHEHGRVVSIEGEPCDPATNDLPYLLPGFIDLHVHGGGGKDIMEGASAFETITKTHVRFGTTS
LLATTMTAPRAEIASVLKEVGEFCEQRPKGAARVLGVHLEGPYINPGKLGAQPNFAHTALMAEVEDYLALAPIRVITIAP
EIAGHDGLIRELSRRGIRMQIGHTLGSYEEGVAALEAGATSFTHLYNAMSPLHHREPGIVGAALAHAKFAELIPDLLHVH
PGAIRVALRSIPCLYCVTDSTAAAGMPDGEYKLGSHTVTKCLGGVRLPDGTLAGSTLTMDQALRNLVKIGLPIAEASQRL
SQFPADYLGITERGRLAPGAWADCVRLDRSLTLTAVMVEGEDIDFKNA
>Mature_367_residues
SEDNILTADGWIRGRLIHEHGRVVSIEGEPCDPATNDLPYLLPGFIDLHVHGGGGKDIMEGASAFETITKTHVRFGTTSL
LATTMTAPRAEIASVLKEVGEFCEQRPKGAARVLGVHLEGPYINPGKLGAQPNFAHTALMAEVEDYLALAPIRVITIAPE
IAGHDGLIRELSRRGIRMQIGHTLGSYEEGVAALEAGATSFTHLYNAMSPLHHREPGIVGAALAHAKFAELIPDLLHVHP
GAIRVALRSIPCLYCVTDSTAAAGMPDGEYKLGSHTVTKCLGGVRLPDGTLAGSTLTMDQALRNLVKIGLPIAEASQRLS
QFPADYLGITERGRLAPGAWADCVRLDRSLTLTAVMVEGEDIDFKNA

Specific function: N-acetylglucosamine utilization. [C]

COG id: COG1820

COG function: function code G; N-acetylglucosamine-6-phosphate deacetylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nagA family [H]

Homologues:

Organism=Homo sapiens, GI21361513, Length=414, Percent_Identity=32.3671497584541, Blast_Score=154, Evalue=2e-37,
Organism=Homo sapiens, GI224922791, Length=413, Percent_Identity=32.2033898305085, Blast_Score=150, Evalue=2e-36,
Organism=Escherichia coli, GI1786892, Length=334, Percent_Identity=34.1317365269461, Blast_Score=144, Evalue=8e-36,
Organism=Caenorhabditis elegans, GI17553768, Length=382, Percent_Identity=32.4607329842932, Blast_Score=149, Evalue=3e-36,
Organism=Drosophila melanogaster, GI19920392, Length=385, Percent_Identity=32.987012987013, Blast_Score=166, Evalue=3e-41,
Organism=Drosophila melanogaster, GI281361140, Length=399, Percent_Identity=31.8295739348371, Blast_Score=160, Evalue=9e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR003764
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.1.25 [H]

Molecular weight: Translated: 39279; Mature: 39147

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEDNILTADGWIRGRLIHEHGRVVSIEGEPCDPATNDLPYLLPGFIDLHVHGGGGKDIM
CCCCCEEECCCCEEEEEEECCCCEEEECCCCCCCCCCCCCEECCCEEEEEEECCCCHHHH
EGASAFETITKTHVRFGTTSLLATTMTAPRAEIASVLKEVGEFCEQRPKGAARVLGVHLE
HHHHHHHHHHHHHHHHCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEC
GPYINPGKLGAQPNFAHTALMAEVEDYLALAPIRVITIAPEIAGHDGLIRELSRRGIRMQ
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCEEEEEECCHHCCCCHHHHHHHHCCCEEE
IGHTLGSYEEGVAALEAGATSFTHLYNAMSPLHHREPGIVGAALAHAKFAELIPDLLHVH
ECCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCC
PGAIRVALRSIPCLYCVTDSTAAAGMPDGEYKLGSHTVTKCLGGVRLPDGTLAGSTLTMD
CHHHHHHHHHCCEEEEECCCCCCCCCCCCCEECCCHHHHHHHCCCCCCCCCCCCCEEEHH
QALRNLVKIGLPIAEASQRLSQFPADYLGITERGRLAPGAWADCVRLDRSLTLTAVMVEG
HHHHHHHHHCCCHHHHHHHHHHCCHHHHCCCCCCCCCCCCHHHHHHHCCCEEEEEEEEEC
EDIDFKNA
CCCCCCCC
>Mature Secondary Structure 
SEDNILTADGWIRGRLIHEHGRVVSIEGEPCDPATNDLPYLLPGFIDLHVHGGGGKDIM
CCCCEEECCCCEEEEEEECCCCEEEECCCCCCCCCCCCCEECCCEEEEEEECCCCHHHH
EGASAFETITKTHVRFGTTSLLATTMTAPRAEIASVLKEVGEFCEQRPKGAARVLGVHLE
HHHHHHHHHHHHHHHHCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEC
GPYINPGKLGAQPNFAHTALMAEVEDYLALAPIRVITIAPEIAGHDGLIRELSRRGIRMQ
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCEEEEEECCHHCCCCHHHHHHHHCCCEEE
IGHTLGSYEEGVAALEAGATSFTHLYNAMSPLHHREPGIVGAALAHAKFAELIPDLLHVH
ECCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCC
PGAIRVALRSIPCLYCVTDSTAAAGMPDGEYKLGSHTVTKCLGGVRLPDGTLAGSTLTMD
CHHHHHHHHHCCEEEEECCCCCCCCCCCCCEECCCHHHHHHHCCCCCCCCCCCCCEEEHH
QALRNLVKIGLPIAEASQRLSQFPADYLGITERGRLAPGAWADCVRLDRSLTLTAVMVEG
HHHHHHHHHCCCHHHHHHHHHHCCHHHHCCCCCCCCCCCCHHHHHHHCCCEEEEEEEEEC
EDIDFKNA
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA