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The map label for this gene is 77457128

Identifier: 77457128

GI number: 77457128

Start: 1043919

End: 1044701

Strand: Direct

Name: 77457128

Synonym: Pfl01_0901

Alternate gene names: NA

Gene position: 1043919-1044701 (Clockwise)

Preceding gene: 77457127

Following gene: 77457129

Centisome position: 16.21

GC content: 61.69

Gene sequence:

>783_bases
GTGAGCGTAGCCCCCGTCCCCTCGTCCGTGAATGTCAAAGACCAGGTCAGTGCCGCGGAATGGCAGACCCGGGTCGATCT
GGCCGCCTGTTATCGTCTGGTCGCGCTGCATGGCTGGGACGATCTGATCTTCACGCACATTTCCGCCAAGGTCCCCGGCA
CCGAAGATTTCCTGATTAACCCGTTCGGCCTGATGTTCCATGAGATCACCGCCTCGAGCCTGGTGAAGGTCGACCAGGCC
GGCAACAAGCTCATGGACAGCCCCTACGAGATCAATCCCGCCGGCTACACCATCCACAGCGCCGTGCACGAAGTGCGGCA
CGACGTGGCCTGCGTGCTGCACACCCACACCGCTTCCGGTGTCGCGGTGTCGGCGCAGAAGCAGGGCGTGCTGCCGATCA
GTCAGCAATCGTTGTTCGTGCTGTCGAGCCTGGCCTTTCACGCTTATGAAGGCGTGGCGCTCAATCACGAAGAGAAAGCG
CGATTGCAGGCCGACCTTGGCGACAGCAATTTCCTGATGCTGCACAACCACGGTCTGCTGACCTGTGGCGGCACCATCGC
CGACACGTTCCTGATGATGTTCACCTTCCAGCGCGCCTGTGACATCCAGGTCATGGCGCAGACCGGCGGTGCCGAACTGA
TCGCCATCGAACCGCAGATTCTGGCGGGCGCCAAGGCGATGATCGCCGGCGTCACCAAAAGTGCTCAAGGCATGGGTGGC
GCGCTGGCCTGGCCGGCGCTGCTGCGCAAACTCGATAAACAAGACCCCGGGTATAAACTCTAA

Upstream 100 bases:

>100_bases
TTCAGTCATCAAGCTGGCTGCCAATGCAACTACGCGACCGTCCGGGGCTGACTAGACTGCTGACACACGCAAAAACAATA
AGAACGCAGAGGTGCATACA

Downstream 100 bases:

>100_bases
TGCCTCTCGCCGAGATCCCTCTGAGTGCCTGGCGCAAACGCAGCCAGACGTTTGTCTTCCGTGGTCAGCCGATCCGCTAC
TGGACGGCCGGGCAGGGCGA

Product: aldolase II superfamily protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 260; Mature: 259

Protein sequence:

>260_residues
MSVAPVPSSVNVKDQVSAAEWQTRVDLAACYRLVALHGWDDLIFTHISAKVPGTEDFLINPFGLMFHEITASSLVKVDQA
GNKLMDSPYEINPAGYTIHSAVHEVRHDVACVLHTHTASGVAVSAQKQGVLPISQQSLFVLSSLAFHAYEGVALNHEEKA
RLQADLGDSNFLMLHNHGLLTCGGTIADTFLMMFTFQRACDIQVMAQTGGAELIAIEPQILAGAKAMIAGVTKSAQGMGG
ALAWPALLRKLDKQDPGYKL

Sequences:

>Translated_260_residues
MSVAPVPSSVNVKDQVSAAEWQTRVDLAACYRLVALHGWDDLIFTHISAKVPGTEDFLINPFGLMFHEITASSLVKVDQA
GNKLMDSPYEINPAGYTIHSAVHEVRHDVACVLHTHTASGVAVSAQKQGVLPISQQSLFVLSSLAFHAYEGVALNHEEKA
RLQADLGDSNFLMLHNHGLLTCGGTIADTFLMMFTFQRACDIQVMAQTGGAELIAIEPQILAGAKAMIAGVTKSAQGMGG
ALAWPALLRKLDKQDPGYKL
>Mature_259_residues
SVAPVPSSVNVKDQVSAAEWQTRVDLAACYRLVALHGWDDLIFTHISAKVPGTEDFLINPFGLMFHEITASSLVKVDQAG
NKLMDSPYEINPAGYTIHSAVHEVRHDVACVLHTHTASGVAVSAQKQGVLPISQQSLFVLSSLAFHAYEGVALNHEEKAR
LQADLGDSNFLMLHNHGLLTCGGTIADTFLMMFTFQRACDIQVMAQTGGAELIAIEPQILAGAKAMIAGVTKSAQGMGGA
LAWPALLRKLDKQDPGYKL

Specific function: Unknown

COG id: COG0235

COG function: function code G; Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldolase class II family [H]

Homologues:

Organism=Homo sapiens, GI29826319, Length=244, Percent_Identity=40.9836065573771, Blast_Score=167, Evalue=8e-42,
Organism=Homo sapiens, GI29826325, Length=244, Percent_Identity=40.9836065573771, Blast_Score=167, Evalue=9e-42,
Organism=Homo sapiens, GI29826323, Length=244, Percent_Identity=40.9836065573771, Blast_Score=167, Evalue=9e-42,
Organism=Homo sapiens, GI29826321, Length=251, Percent_Identity=40.6374501992032, Blast_Score=167, Evalue=9e-42,
Organism=Homo sapiens, GI9951927, Length=256, Percent_Identity=38.28125, Blast_Score=145, Evalue=4e-35,
Organism=Homo sapiens, GI62912453, Length=256, Percent_Identity=38.28125, Blast_Score=145, Evalue=4e-35,
Organism=Homo sapiens, GI9943848, Length=256, Percent_Identity=38.28125, Blast_Score=145, Evalue=4e-35,
Organism=Homo sapiens, GI89276787, Length=201, Percent_Identity=37.3134328358209, Blast_Score=133, Evalue=2e-31,
Organism=Homo sapiens, GI297307160, Length=201, Percent_Identity=37.3134328358209, Blast_Score=133, Evalue=2e-31,
Organism=Homo sapiens, GI9257190, Length=201, Percent_Identity=37.3134328358209, Blast_Score=133, Evalue=2e-31,
Organism=Homo sapiens, GI297307158, Length=201, Percent_Identity=37.3134328358209, Blast_Score=132, Evalue=2e-31,
Organism=Homo sapiens, GI9257192, Length=201, Percent_Identity=37.3134328358209, Blast_Score=132, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI115533216, Length=261, Percent_Identity=38.6973180076628, Blast_Score=164, Evalue=3e-41,
Organism=Caenorhabditis elegans, GI115533218, Length=256, Percent_Identity=38.28125, Blast_Score=164, Evalue=5e-41,
Organism=Caenorhabditis elegans, GI71989550, Length=250, Percent_Identity=33.6, Blast_Score=128, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI71989541, Length=250, Percent_Identity=33.6, Blast_Score=128, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI71989560, Length=250, Percent_Identity=33.6, Blast_Score=128, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI71989555, Length=250, Percent_Identity=33.6, Blast_Score=128, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI71989544, Length=250, Percent_Identity=33.6, Blast_Score=128, Evalue=3e-30,
Organism=Drosophila melanogaster, GI281363755, Length=200, Percent_Identity=36, Blast_Score=126, Evalue=1e-29,
Organism=Drosophila melanogaster, GI281363751, Length=200, Percent_Identity=36, Blast_Score=126, Evalue=1e-29,
Organism=Drosophila melanogaster, GI24655690, Length=200, Percent_Identity=36, Blast_Score=126, Evalue=1e-29,
Organism=Drosophila melanogaster, GI24655685, Length=185, Percent_Identity=37.8378378378378, Blast_Score=125, Evalue=2e-29,
Organism=Drosophila melanogaster, GI281363761, Length=185, Percent_Identity=37.8378378378378, Blast_Score=125, Evalue=3e-29,
Organism=Drosophila melanogaster, GI281363759, Length=185, Percent_Identity=37.8378378378378, Blast_Score=125, Evalue=3e-29,
Organism=Drosophila melanogaster, GI281363753, Length=185, Percent_Identity=37.8378378378378, Blast_Score=125, Evalue=3e-29,
Organism=Drosophila melanogaster, GI281363763, Length=185, Percent_Identity=37.8378378378378, Blast_Score=125, Evalue=4e-29,
Organism=Drosophila melanogaster, GI281363757, Length=185, Percent_Identity=37.8378378378378, Blast_Score=125, Evalue=4e-29,
Organism=Drosophila melanogaster, GI17136738, Length=185, Percent_Identity=37.8378378378378, Blast_Score=125, Evalue=4e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001303 [H]

Pfam domain/function: PF00596 Aldolase_II [H]

EC number: NA

Molecular weight: Translated: 27919; Mature: 27788

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVAPVPSSVNVKDQVSAAEWQTRVDLAACYRLVALHGWDDLIFTHISAKVPGTEDFLIN
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEEEEECCCCCCCCEEEC
PFGLMFHEITASSLVKVDQAGNKLMDSPYEINPAGYTIHSAVHEVRHDVACVLHTHTASG
HHHHHHHHHHHHHHHHHHHCCCHHCCCCEEECCCCCHHHHHHHHHHHHHEEEEEECCCCC
VAVSAQKQGVLPISQQSLFVLSSLAFHAYEGVALNHEEKARLQADLGDSNFLMLHNHGLL
EEEECCCCCCCCCCCHHHHHHHHHHHHHHCCEEECCHHHHHHEECCCCCCEEEEECCCEE
TCGGTIADTFLMMFTFQRACDIQVMAQTGGAELIAIEPQILAGAKAMIAGVTKSAQGMGG
EECHHHHHHHHHHHHHHHHCCEEEEEECCCEEEEEECCHHHHCHHHHHHHHHHCCCCCCC
ALAWPALLRKLDKQDPGYKL
HHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
SVAPVPSSVNVKDQVSAAEWQTRVDLAACYRLVALHGWDDLIFTHISAKVPGTEDFLIN
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEEEEECCCCCCCCEEEC
PFGLMFHEITASSLVKVDQAGNKLMDSPYEINPAGYTIHSAVHEVRHDVACVLHTHTASG
HHHHHHHHHHHHHHHHHHHCCCHHCCCCEEECCCCCHHHHHHHHHHHHHEEEEEECCCCC
VAVSAQKQGVLPISQQSLFVLSSLAFHAYEGVALNHEEKARLQADLGDSNFLMLHNHGLL
EEEECCCCCCCCCCCHHHHHHHHHHHHHHCCEEECCHHHHHHEECCCCCCEEEEECCCEE
TCGGTIADTFLMMFTFQRACDIQVMAQTGGAELIAIEPQILAGAKAMIAGVTKSAQGMGG
EECHHHHHHHHHHHHHHHHCCEEEEEECCCEEEEEECCHHHHCHHHHHHHHHHCCCCCCC
ALAWPALLRKLDKQDPGYKL
HHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]