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The map label for this gene is regA [H]

Identifier: 77457048

GI number: 77457048

Start: 968853

End: 969413

Strand: Direct

Name: regA [H]

Synonym: Pfl01_0821

Alternate gene names: 77457048

Gene position: 968853-969413 (Clockwise)

Preceding gene: 77457047

Following gene: 77457049

Centisome position: 15.05

GC content: 64.53

Gene sequence:

>561_bases
ATGAGTGACGAAATCCAAGTCGAAGGCGAAGAACTGCCGCATTTGCTGCTGGTCGACGATGACGCGACCTTCACCCGGGT
GATGGCCCGTGCCATGGCCCGCCGTGGTTTCCGCGTCAGCACCGCCGGTTCCGCCGAGGAAGGCCTGACCATCGCCCAGG
CCGATCTGCCGGATTACGCCGCGCTGGACCTGAAAATGGACGGCGATTCCGGTCTGGTGCTGCTGCCAAAACTGCTGGAG
CTGGACCCGGAAATGCGCGTGGTGATCCTCACCGGTTACTCGAGCATTGCCACGGCGGTTGAAGCGATCAAGCGCGGCGC
CTGCAACTATCTGTGCAAACCGGCGGATGCCGACGATGTGCTGGCAGCGCTGCTGTCCGAACACGCCGACCTCGACAGCC
TGGTGCCGGAAAACCCGATGTCGGTGGATCGCCTGCAGTGGGAGCACATCCAGCGCGTGCTGACCGAGCACGAAGGCAAC
ATCTCCGCCACGGCCCGCGCCCTGGGCATGCACCGCCGCACCCTGCAGCGCAAATTGCAGAAGCGCCCGGTTCGTCGCTG
A

Upstream 100 bases:

>100_bases
AGCGTGACACGCGCCGGCGGCTCAGTGAAACTCTATAGTCATGAGGAAGGCGGCACGCTCACCGAGCTGCGCCTGCCCCA
CGGCGCCCGAGGAGAGCAAC

Downstream 100 bases:

>100_bases
ACCTGCGCTGAACGACCATCGCCAGCCCTCGCGATAAAGCGCACCGATCATCTATGATCGGTGCGTGTCTGTTCTTTTCT
TTATCGAGCCTTTTTCATGA

Product: two component Fis family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 186; Mature: 185

Protein sequence:

>186_residues
MSDEIQVEGEELPHLLLVDDDATFTRVMARAMARRGFRVSTAGSAEEGLTIAQADLPDYAALDLKMDGDSGLVLLPKLLE
LDPEMRVVILTGYSSIATAVEAIKRGACNYLCKPADADDVLAALLSEHADLDSLVPENPMSVDRLQWEHIQRVLTEHEGN
ISATARALGMHRRTLQRKLQKRPVRR

Sequences:

>Translated_186_residues
MSDEIQVEGEELPHLLLVDDDATFTRVMARAMARRGFRVSTAGSAEEGLTIAQADLPDYAALDLKMDGDSGLVLLPKLLE
LDPEMRVVILTGYSSIATAVEAIKRGACNYLCKPADADDVLAALLSEHADLDSLVPENPMSVDRLQWEHIQRVLTEHEGN
ISATARALGMHRRTLQRKLQKRPVRR
>Mature_185_residues
SDEIQVEGEELPHLLLVDDDATFTRVMARAMARRGFRVSTAGSAEEGLTIAQADLPDYAALDLKMDGDSGLVLLPKLLEL
DPEMRVVILTGYSSIATAVEAIKRGACNYLCKPADADDVLAALLSEHADLDSLVPENPMSVDRLQWEHIQRVLTEHEGNI
SATARALGMHRRTLQRKLQKRPVRR

Specific function: Member of the two-component regulatory system regB/regA. Involved in transactivating anaerobic expression of the photosynthetic apparatus. It is a transcriptional regulator that is responsible for activating expression of the puf, puh, and puc operons in

COG id: COG4567

COG function: function code TK; Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=125, Percent_Identity=34.4, Blast_Score=75, Evalue=2e-15,
Organism=Escherichia coli, GI1788905, Length=111, Percent_Identity=36.9369369369369, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI1790299, Length=108, Percent_Identity=35.1851851851852, Blast_Score=70, Evalue=8e-14,
Organism=Escherichia coli, GI1788550, Length=141, Percent_Identity=29.0780141843972, Blast_Score=64, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR002197
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 20542; Mature: 20411

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDEIQVEGEELPHLLLVDDDATFTRVMARAMARRGFRVSTAGSAEEGLTIAQADLPDYA
CCCCEEECCCCCCEEEEEECCCHHHHHHHHHHHHCCCEEECCCCCCCCCEEEECCCCCCE
ALDLKMDGDSGLVLLPKLLELDPEMRVVILTGYSSIATAVEAIKRGACNYLCKPADADDV
EEEEEECCCCCEEECCHHHCCCCCCEEEEEECCHHHHHHHHHHHHCCHHCCCCCCCHHHH
LAALLSEHADLDSLVPENPMSVDRLQWEHIQRVLTEHEGNISATARALGMHRRTLQRKLQ
HHHHHHHCCCHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
KRPVRR
HCCCCC
>Mature Secondary Structure 
SDEIQVEGEELPHLLLVDDDATFTRVMARAMARRGFRVSTAGSAEEGLTIAQADLPDYA
CCCEEECCCCCCEEEEEECCCHHHHHHHHHHHHCCCEEECCCCCCCCCEEEECCCCCCE
ALDLKMDGDSGLVLLPKLLELDPEMRVVILTGYSSIATAVEAIKRGACNYLCKPADADDV
EEEEEECCCCCEEECCHHHCCCCCCEEEEEECCHHHHHHHHHHHHCCHHCCCCCCCHHHH
LAALLSEHADLDSLVPENPMSVDRLQWEHIQRVLTEHEGNISATARALGMHRRTLQRKLQ
HHHHHHHCCCHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
KRPVRR
HCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA