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The map label for this gene is regB [H]

Identifier: 77457047

GI number: 77457047

Start: 967598

End: 968860

Strand: Direct

Name: regB [H]

Synonym: Pfl01_0820

Alternate gene names: 77457047

Gene position: 967598-968860 (Clockwise)

Preceding gene: 77457046

Following gene: 77457048

Centisome position: 15.03

GC content: 62.31

Gene sequence:

>1263_bases
ATGCTCGCCCCCGTACAACTGACTTCCGCCACTCGCCAGAACCTCTGGCGGCTGACTTTCATCCGCACCCTGGTGCTCGC
CGCGCAGGCCGGCTCCGTGGGCCTGGCTTACTGGCTGGACCTCTTGCCGTTGCCGTGGGTGCAACTGGTGATGACCCTCG
GCTGTTCGATTCTGCTGTGTGTGTTCACCGCCGTGCGTTTGCGCACTTCGTGGCCGGTTACCGAGCTCGAATACGCGCTG
CAACTGGCCTGCGATCTGGTTATCCACAGCGCCTTGCTGTATTTCTCCGGTGGTTCGACCAACCCGTTCGTTTCGTATTA
TCTGGTGCCGCTGACCATCGCTGCGGTGACGCTGCCATGGCGTTATTCGGTGGTGCTGTCGGGCATTGCGCTGGCCTTGT
ATACGCTGATGCTGACGCACTTCTATCCACTGGAAACCCTGCCGGTGGCCCGGGAGAACCTGCAGATCTACGGCATGTGG
CTGAGTTTTGCCCTCGCGGCAGCAGTGATCACCTTCTTCGCCGCGCGGATGGCCGAAGAGCTGCGCCGTCAGGAAGAATT
GCGAGCGATCCGTCGCGAAGAAGGCCTGCGCGATCAGCAATTGCTGGCCGTGGCGACTCAGGCCGCCGGTGCCGCTCATG
AACTGGGTACGCCGCTGGCGACCATGAGCGTGTTGCTCAACGAAATGCAGCAGGATCATCACGACCCGATGCTTCAGGAA
GACCTGAAGGTGCTGAAGGATCAGGTGAAGCTCTGCAAGGAGACTCTGCAACAACTGGTGCGCGCCGCCGAAGCCAACCG
CCGGATGGCGGTGGAGATGCAGGACGTCACCGAGTGGCTCGACGAAGCGCTCAATCGCTGGCACCTGATGCGCCCGGAAG
CCAGTTACCGCTTCCAGCGTCTGGGCCAGGGCCCGTTGCCGCGTGTGGCGCCGCCGCCGGATCTGACTCAGGCCTTGTTG
AATCTGTTGAACAACGCCGCCGATGCCTGCCCGGAAAACCTTCAGGTGACCCTGGACTGGACCGCCGAAGACCTGACCAT
CAGCATCCGCGATCATGGCGCCGGTGTGCCGCTGGCCATCGCCGAGCAGATCGGCAAACCGTTTTTTACCACCAAGGGCA
AAGGTTTCGGCCTGGGCCTGTTTTTGAGCAAGGCCAGCGTGACACGCGCCGGCGGCTCAGTGAAACTCTATAGTCATGAG
GAAGGCGGCACGCTCACCGAGCTGCGCCTGCCCCACGGCGCCCGAGGAGAGCAACATGAGTGA

Upstream 100 bases:

>100_bases
ATCTTTGCGCCATGTGGTCGTTTGCCGCACTTTCGCCTCTCAAGCCCGCGCCTTGGTTATACTCCGTGCGATCCGCCTGG
AGCGCTCATCAGGAGAGCTC

Downstream 100 bases:

>100_bases
CGAAATCCAAGTCGAAGGCGAAGAACTGCCGCATTTGCTGCTGGTCGACGATGACGCGACCTTCACCCGGGTGATGGCCC
GTGCCATGGCCCGCCGTGGT

Product: periplasmic sensor Signal transduction histidine kinase

Products: NA

Alternate protein names: Protein prrB [H]

Number of amino acids: Translated: 420; Mature: 420

Protein sequence:

>420_residues
MLAPVQLTSATRQNLWRLTFIRTLVLAAQAGSVGLAYWLDLLPLPWVQLVMTLGCSILLCVFTAVRLRTSWPVTELEYAL
QLACDLVIHSALLYFSGGSTNPFVSYYLVPLTIAAVTLPWRYSVVLSGIALALYTLMLTHFYPLETLPVARENLQIYGMW
LSFALAAAVITFFAARMAEELRRQEELRAIRREEGLRDQQLLAVATQAAGAAHELGTPLATMSVLLNEMQQDHHDPMLQE
DLKVLKDQVKLCKETLQQLVRAAEANRRMAVEMQDVTEWLDEALNRWHLMRPEASYRFQRLGQGPLPRVAPPPDLTQALL
NLLNNAADACPENLQVTLDWTAEDLTISIRDHGAGVPLAIAEQIGKPFFTTKGKGFGLGLFLSKASVTRAGGSVKLYSHE
EGGTLTELRLPHGARGEQHE

Sequences:

>Translated_420_residues
MLAPVQLTSATRQNLWRLTFIRTLVLAAQAGSVGLAYWLDLLPLPWVQLVMTLGCSILLCVFTAVRLRTSWPVTELEYAL
QLACDLVIHSALLYFSGGSTNPFVSYYLVPLTIAAVTLPWRYSVVLSGIALALYTLMLTHFYPLETLPVARENLQIYGMW
LSFALAAAVITFFAARMAEELRRQEELRAIRREEGLRDQQLLAVATQAAGAAHELGTPLATMSVLLNEMQQDHHDPMLQE
DLKVLKDQVKLCKETLQQLVRAAEANRRMAVEMQDVTEWLDEALNRWHLMRPEASYRFQRLGQGPLPRVAPPPDLTQALL
NLLNNAADACPENLQVTLDWTAEDLTISIRDHGAGVPLAIAEQIGKPFFTTKGKGFGLGLFLSKASVTRAGGSVKLYSHE
EGGTLTELRLPHGARGEQHE
>Mature_420_residues
MLAPVQLTSATRQNLWRLTFIRTLVLAAQAGSVGLAYWLDLLPLPWVQLVMTLGCSILLCVFTAVRLRTSWPVTELEYAL
QLACDLVIHSALLYFSGGSTNPFVSYYLVPLTIAAVTLPWRYSVVLSGIALALYTLMLTHFYPLETLPVARENLQIYGMW
LSFALAAAVITFFAARMAEELRRQEELRAIRREEGLRDQQLLAVATQAAGAAHELGTPLATMSVLLNEMQQDHHDPMLQE
DLKVLKDQVKLCKETLQQLVRAAEANRRMAVEMQDVTEWLDEALNRWHLMRPEASYRFQRLGQGPLPRVAPPPDLTQALL
NLLNNAADACPENLQVTLDWTAEDLTISIRDHGAGVPLAIAEQIGKPFFTTKGKGFGLGLFLSKASVTRAGGSVKLYSHE
EGGTLTELRLPHGARGEQHE

Specific function: Member of the two-component regulatory system RegB/RegA. Involved in the positive regulation of photosynthesis gene expression in response to anaerobiosis. Also involved in positive regulation of the cbbI and cbbII Calvin cycle CO2 fixation operons, as we

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=273, Percent_Identity=28.5714285714286, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1788549, Length=216, Percent_Identity=31.4814814814815, Blast_Score=80, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 46678; Mature: 46678

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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>Mature Secondary Structure
MLAPVQLTSATRQNLWRLTFIRTLVLAAQAGSVGLAYWLDLLPLPWVQLVMTLGCSILLC
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHH
VFTAVRLRTSWPVTELEYALQLACDLVIHSALLYFSGGSTNPFVSYYLVPLTIAAVTLPW
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCH
RYSVVLSGIALALYTLMLTHFYPLETLPVARENLQIYGMWLSFALAAAVITFFAARMAEE
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCHHEEHHHHHHHHHHHHHHHHHHHHHHH
LRRQEELRAIRREEGLRDQQLLAVATQAAGAAHELGTPLATMSVLLNEMQQDHHDPMLQE
HHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHHHCCCCHHHH
DLKVLKDQVKLCKETLQQLVRAAEANRRMAVEMQDVTEWLDEALNRWHLMRPEASYRFQR
HHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHEECCCCHHHHHHH
LGQGPLPRVAPPPDLTQALLNLLNNAADACPENLQVTLDWTAEDLTISIRDHGAGVPLAI
CCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEEEECCCCCCCHHH
AEQIGKPFFTTKGKGFGLGLFLSKASVTRAGGSVKLYSHEEGGTLTELRLPHGARGEQHE
HHHHCCCCEECCCCCCEEHHEEEHHHHHCCCCEEEEEEECCCCCEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7751278; 10358089 [H]