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The map label for this gene is dapB

Identifier: 77456992

GI number: 77456992

Start: 898270

End: 899076

Strand: Direct

Name: dapB

Synonym: Pfl01_0765

Alternate gene names: 77456992

Gene position: 898270-899076 (Clockwise)

Preceding gene: 77456991

Following gene: 77456993

Centisome position: 13.95

GC content: 61.83

Gene sequence:

>807_bases
ATGCGACGTATAGCTGTGATGGGCGCTGCCGGGCGCATGGGCAAGATTCTGGTCGAGGCGGTGCAGCAGCGCGCGCCACT
GACCGGTCTGACGGCCGCGATTGTCCGCCCTGGCAGTACGCTGATCGGTGTGGATGCCGGTGAGCTGGCTTCGCTCGGTC
GAATCGGCGTGCCGCTGTCCGGGAATCTGGAATCAGTGGCGGAAGAGTTCGATGTGTTGATCGACTTCACCCTGCCGGAA
GTGATGCTGAAAAACCTGGCCTTCTGCCGCAAGGCCGGCAAGGCGATGGTGATCGGCACGACCGGGCTGGACGCTGCGCA
GAAGCAGTTGCTGGCCGAGGCGGGCAAGGATATTCCGATCGTGTTCGCCGCCAACTTCAGTGTCGGCGTCAACCTGTCGC
TGAAGCTGCTCGACATGGCGGCACGGGTGTTGGCGGAAGATGCGGACATCGAAATCATCGAAGCCCATCACCGGCACAAG
ATTGATGCGCCGTCGGGTACGGCCTTGCGCATGGGTGAAGTGATCGCCAATGCGCTGGATCGTGATCTGCAGAAAGTCGC
GGTCTATGGTCGTGAAGGCCACACTGGTGCCCGTGAGCGTGAAACTATCGGCTTTGCCACTGTTCGCGGTGGTGATGTAG
TGGGCGATCACACGGTGTTGTTTGCCTGCGAGGGCGAGCGGCTGGAGATCACGCACAAGGCTTCGAGTCGCATGACATTC
GCCAAGGGCGCGGTGCGTGCGGCGTTGTGGCTGGATGCTCGCGAGCCTGGTTTGTACGACATGCAGGACGTGCTCGGCCT
GCATTGA

Upstream 100 bases:

>100_bases
GTTCCGCAGCTCCCTGGCGGACGACAACAGCCACTCCCCGAAAACCACCGGTTGGTTCGACGGTGTGAAACGCTTCTTCG
GCGATCTGTAAGGAGTCGGC

Downstream 100 bases:

>100_bases
GATGTTCTGAAGCCGGCGCAAACGCCCTGTTTGTGCCGGTTTTGCTCCGCCGGGCGACGCCCTGTCGCATTCTCCGGCCT
TTCAGGCTCATTGGCGGTAG

Product: dihydrodipicolinate reductase

Products: NA

Alternate protein names: DHPR

Number of amino acids: Translated: 268; Mature: 268

Protein sequence:

>268_residues
MRRIAVMGAAGRMGKILVEAVQQRAPLTGLTAAIVRPGSTLIGVDAGELASLGRIGVPLSGNLESVAEEFDVLIDFTLPE
VMLKNLAFCRKAGKAMVIGTTGLDAAQKQLLAEAGKDIPIVFAANFSVGVNLSLKLLDMAARVLAEDADIEIIEAHHRHK
IDAPSGTALRMGEVIANALDRDLQKVAVYGREGHTGARERETIGFATVRGGDVVGDHTVLFACEGERLEITHKASSRMTF
AKGAVRAALWLDAREPGLYDMQDVLGLH

Sequences:

>Translated_268_residues
MRRIAVMGAAGRMGKILVEAVQQRAPLTGLTAAIVRPGSTLIGVDAGELASLGRIGVPLSGNLESVAEEFDVLIDFTLPE
VMLKNLAFCRKAGKAMVIGTTGLDAAQKQLLAEAGKDIPIVFAANFSVGVNLSLKLLDMAARVLAEDADIEIIEAHHRHK
IDAPSGTALRMGEVIANALDRDLQKVAVYGREGHTGARERETIGFATVRGGDVVGDHTVLFACEGERLEITHKASSRMTF
AKGAVRAALWLDAREPGLYDMQDVLGLH
>Mature_268_residues
MRRIAVMGAAGRMGKILVEAVQQRAPLTGLTAAIVRPGSTLIGVDAGELASLGRIGVPLSGNLESVAEEFDVLIDFTLPE
VMLKNLAFCRKAGKAMVIGTTGLDAAQKQLLAEAGKDIPIVFAANFSVGVNLSLKLLDMAARVLAEDADIEIIEAHHRHK
IDAPSGTALRMGEVIANALDRDLQKVAVYGREGHTGARERETIGFATVRGGDVVGDHTVLFACEGERLEITHKASSRMTF
AKGAVRAALWLDAREPGLYDMQDVLGLH

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; second step. [C]

COG id: COG0289

COG function: function code E; Dihydrodipicolinate reductase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydrodipicolinate reductase family

Homologues:

Organism=Escherichia coli, GI1786214, Length=266, Percent_Identity=63.5338345864662, Blast_Score=323, Evalue=1e-89,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DAPB_PSEPF (Q3KI98)

Other databases:

- EMBL:   CP000094
- RefSeq:   YP_346497.1
- ProteinModelPortal:   Q3KI98
- SMR:   Q3KI98
- STRING:   Q3KI98
- GeneID:   3715223
- GenomeReviews:   CP000094_GR
- KEGG:   pfo:Pfl01_0765
- eggNOG:   COG0289
- HOGENOM:   HBG594002
- OMA:   GRMGKTL
- ProtClustDB:   PRK00048
- BioCyc:   PFLU205922:PFL_0765-MONOMER
- GO:   GO:0005737
- GO:   GO:0005488
- HAMAP:   MF_00102
- InterPro:   IPR022663
- InterPro:   IPR000846
- InterPro:   IPR022664
- InterPro:   IPR011770
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR20836
- TIGRFAMs:   TIGR00036

Pfam domain/function: PF05173 DapB_C; PF01113 DapB_N

EC number: =1.3.1.26

Molecular weight: Translated: 28499; Mature: 28499

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: PS01298 DAPB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRIAVMGAAGRMGKILVEAVQQRAPLTGLTAAIVRPGSTLIGVDAGELASLGRIGVPLS
CCEEEEEECCCHHHHHHHHHHHHCCCCCCCHHHEECCCCEEEECCCHHHHHCCCCCCCCC
GNLESVAEEFDVLIDFTLPEVMLKNLAFCRKAGKAMVIGTTGLDAAQKQLLAEAGKDIPI
CCHHHHHHHHHEEEECCHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHCCCCCEE
VFAANFSVGVNLSLKLLDMAARVLAEDADIEIIEAHHRHKIDAPSGTALRMGEVIANALD
EEEECCEECCCEEHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHH
RDLQKVAVYGREGHTGARERETIGFATVRGGDVVGDHTVLFACEGERLEITHKASSRMTF
HHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCEECCCEEEEEECCCEEEEEECCCCCEEH
AKGAVRAALWLDAREPGLYDMQDVLGLH
HHHHHEEEEEEECCCCCCCCHHHHHCCC
>Mature Secondary Structure
MRRIAVMGAAGRMGKILVEAVQQRAPLTGLTAAIVRPGSTLIGVDAGELASLGRIGVPLS
CCEEEEEECCCHHHHHHHHHHHHCCCCCCCHHHEECCCCEEEECCCHHHHHCCCCCCCCC
GNLESVAEEFDVLIDFTLPEVMLKNLAFCRKAGKAMVIGTTGLDAAQKQLLAEAGKDIPI
CCHHHHHHHHHEEEECCHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHCCCCCEE
VFAANFSVGVNLSLKLLDMAARVLAEDADIEIIEAHHRHKIDAPSGTALRMGEVIANALD
EEEECCEECCCEEHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHH
RDLQKVAVYGREGHTGARERETIGFATVRGGDVVGDHTVLFACEGERLEITHKASSRMTF
HHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCEECCCEEEEEECCCEEEEEECCCCCEEH
AKGAVRAALWLDAREPGLYDMQDVLGLH
HHHHHEEEEEEECCCCCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA