Click here to switch to the map view.

The map label for this gene is gntP [H]

Identifier: 77456949

GI number: 77456949

Start: 848776

End: 850125

Strand: Direct

Name: gntP [H]

Synonym: Pfl01_0721

Alternate gene names: 77456949

Gene position: 848776-850125 (Clockwise)

Preceding gene: 77456948

Following gene: 77456950

Centisome position: 13.18

GC content: 62.22

Gene sequence:

>1350_bases
ATGACACCGTCCTTCGGCTATTGGCTGCTGGTGTACGCCGCCGTTGCCATCATCGCCCTGATCGTTCTGATCGCCCGTTA
CCGGCTCAATCCGTTCATTGTCATCACCCTGATTTCCATCGGCCTGGCGCTGGTGGCGGGGATGCCGCCGTCCGGCGTGG
TGGGGGCTTACGAGGCCGGGGTGGGCAAGACGCTGGGGCACATTGCGCTGGTGGTGGCGCTGGGGACGATGCTCGGCAAG
ATGATGGCCGAGTCCGGTGGCGCCGAGCAGATGGCGCGCACGTTGATCGAGCGTTTTGGCGAGAAGAACGCGCACTGGGC
GATGGTGTGCATTGCGTTTCTGGTGGGACTGCCGCTGTTTTTCGAAGTCGGCTTCGTGTTGCTGGTGCCGATTGCCTTTA
CCGTGGCGCGGCGGGTGGGCGTGTCGATCCTGATGGTCGGTTTGCCGATGGTCGCGGGTCTGTCGGTGGTGCATGCGCTG
GTGCCGCCTCATCCGGCGGCGATGCTGGCGGTGCAGGCTTATCAGGCGTCGGTCGGGCAGACCTTGCTGTATGCGATTGC
CATCGGCATTCCGACGGCGATCATTGCCGGCCCCCTGTACGCCAAATTCATCGTGCCGCGCATTCAGTTGCCGGCGGATA
ACCCGCTGGAAAAACAATTTCTCGAACGCGAACCCCGCGACAGCCTGCCGGGTTTCGGCATCACCATGGCGACCATTCTG
TTGCCGGTGGTGCTGATGTTGATCGGCGGCTGGGCCAACCTGATTGCCACGCCGGGCAGCGCTTTCAATCAGTTCCTGTT
GTTCATCGGCAACTCGGTGATCGCGCTGTTGCTGGCGACGCTGTTGAGTTTCTGGACCCTCGGCATTGCCCAGGGTTTCA
ACCGCGAATCGATCCTCAAATTCACCAACGAATGCCTGGCACCGACCGCCAGCATCACCTTGCTGGTGGGCGCCGGTGGC
GGTCTGAACCGGATTCTGGTGGACGCCGGCGTCACCGATCAGATCGTCGGCCTCGCTCACGAATTTCATTTGTCGCCGCT
GATCATGGGCTGGCTGTTCGCCGCGTTGATGCGCATCGCCACCGGTTCGGCCACGGTCGCGATGACCACGGCTTCCGGCG
TGGTCGCGCCAGTGGCCATCGGTCTGGGTTATCCCCACCCGGAACTGCTGGTGCTGGCGACCGGCGCGGGCTCGGTTATC
TTTTCCCACGTCAACGACGGCGGCTTCTGGTTGATCAAGGAATACTTCAACATGACCGTGGCCCAGACGTTCAAGACCTG
GACGGTGCTGGAAACCCTGATCTCGATTGTCGCTTTCGCCCTGACCGTCGGTCTTTCTTACCTGCTGTAG

Upstream 100 bases:

>100_bases
CCTCCACGAAAATTACTTTCACTTGGTTTGAAAACTCGATCTCGAAATGATTTATGAGTTTCACAACCCATTCGAACGTG
ACCCTTTCGAGGAGTACCGC

Downstream 100 bases:

>100_bases
TCGGAGTTATCCGCCATGGACATCCTTTATCAGATCCGCGCCCGTCAGGATTCCTTCAGCGCCGGTGAAGGACGCATCGC
CCGTCTGATGCTCGACGACG

Product: gluconate transporter

Products: Proton [Cytoplasm]; gluconate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 449; Mature: 448

Protein sequence:

>449_residues
MTPSFGYWLLVYAAVAIIALIVLIARYRLNPFIVITLISIGLALVAGMPPSGVVGAYEAGVGKTLGHIALVVALGTMLGK
MMAESGGAEQMARTLIERFGEKNAHWAMVCIAFLVGLPLFFEVGFVLLVPIAFTVARRVGVSILMVGLPMVAGLSVVHAL
VPPHPAAMLAVQAYQASVGQTLLYAIAIGIPTAIIAGPLYAKFIVPRIQLPADNPLEKQFLEREPRDSLPGFGITMATIL
LPVVLMLIGGWANLIATPGSAFNQFLLFIGNSVIALLLATLLSFWTLGIAQGFNRESILKFTNECLAPTASITLLVGAGG
GLNRILVDAGVTDQIVGLAHEFHLSPLIMGWLFAALMRIATGSATVAMTTASGVVAPVAIGLGYPHPELLVLATGAGSVI
FSHVNDGGFWLIKEYFNMTVAQTFKTWTVLETLISIVAFALTVGLSYLL

Sequences:

>Translated_449_residues
MTPSFGYWLLVYAAVAIIALIVLIARYRLNPFIVITLISIGLALVAGMPPSGVVGAYEAGVGKTLGHIALVVALGTMLGK
MMAESGGAEQMARTLIERFGEKNAHWAMVCIAFLVGLPLFFEVGFVLLVPIAFTVARRVGVSILMVGLPMVAGLSVVHAL
VPPHPAAMLAVQAYQASVGQTLLYAIAIGIPTAIIAGPLYAKFIVPRIQLPADNPLEKQFLEREPRDSLPGFGITMATIL
LPVVLMLIGGWANLIATPGSAFNQFLLFIGNSVIALLLATLLSFWTLGIAQGFNRESILKFTNECLAPTASITLLVGAGG
GLNRILVDAGVTDQIVGLAHEFHLSPLIMGWLFAALMRIATGSATVAMTTASGVVAPVAIGLGYPHPELLVLATGAGSVI
FSHVNDGGFWLIKEYFNMTVAQTFKTWTVLETLISIVAFALTVGLSYLL
>Mature_448_residues
TPSFGYWLLVYAAVAIIALIVLIARYRLNPFIVITLISIGLALVAGMPPSGVVGAYEAGVGKTLGHIALVVALGTMLGKM
MAESGGAEQMARTLIERFGEKNAHWAMVCIAFLVGLPLFFEVGFVLLVPIAFTVARRVGVSILMVGLPMVAGLSVVHALV
PPHPAAMLAVQAYQASVGQTLLYAIAIGIPTAIIAGPLYAKFIVPRIQLPADNPLEKQFLEREPRDSLPGFGITMATILL
PVVLMLIGGWANLIATPGSAFNQFLLFIGNSVIALLLATLLSFWTLGIAQGFNRESILKFTNECLAPTASITLLVGAGGG
LNRILVDAGVTDQIVGLAHEFHLSPLIMGWLFAALMRIATGSATVAMTTASGVVAPVAIGLGYPHPELLVLATGAGSVIF
SHVNDGGFWLIKEYFNMTVAQTFKTWTVLETLISIVAFALTVGLSYLL

Specific function: Part Of The Gluconate Utilization System Gnt-I; High- Affinity Intake Of Gluconate. [C]

COG id: COG2610

COG function: function code GE; H+/gluconate symporter and related permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gntP permease family [H]

Homologues:

Organism=Escherichia coli, GI48994935, Length=429, Percent_Identity=44.7552447552448, Blast_Score=351, Evalue=5e-98,
Organism=Escherichia coli, GI1790716, Length=428, Percent_Identity=41.1214953271028, Blast_Score=324, Evalue=9e-90,
Organism=Escherichia coli, GI2367370, Length=418, Percent_Identity=39.9521531100478, Blast_Score=295, Evalue=4e-81,
Organism=Escherichia coli, GI1788707, Length=446, Percent_Identity=35.8744394618834, Blast_Score=278, Evalue=5e-76,
Organism=Escherichia coli, GI1790776, Length=429, Percent_Identity=32.8671328671329, Blast_Score=251, Evalue=7e-68,
Organism=Escherichia coli, GI48994939, Length=431, Percent_Identity=35.2668213457077, Blast_Score=236, Evalue=3e-63,
Organism=Escherichia coli, GI1789097, Length=444, Percent_Identity=32.4324324324324, Blast_Score=217, Evalue=1e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003474 [H]

Pfam domain/function: PF02447 GntP_permease [H]

EC number: NA

Molecular weight: Translated: 47376; Mature: 47245

Theoretical pI: Translated: 7.73; Mature: 7.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure 
TPSFGYWLLVYAAVAIIALIVLIARYRLNPFIVITLISIGLALVAGMPPSGVVGAYEAG
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHC
VGKTLGHIALVVALGTMLGKMMAESGGAEQMARTLIERFGEKNAHWAMVCIAFLVGLPLF
CHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
FEVGFVLLVPIAFTVARRVGVSILMVGLPMVAGLSVVHALVPPHPAAMLAVQAYQASVGQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
TLLYAIAIGIPTAIIAGPLYAKFIVPRIQLPADNPLEKQFLEREPRDSLPGFGITMATIL
HHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCHHHHHHHCCCCCCCCCCHHHHHHHH
LPVVLMLIGGWANLIATPGSAFNQFLLFIGNSVIALLLATLLSFWTLGIAQGFNRESILK
HHHHHHHHCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
FTNECLAPTASITLLVGAGGGLNRILVDAGVTDQIVGLAHEFHLSPLIMGWLFAALMRIA
HHHHHCCCCCEEEEEEECCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TGSATVAMTTASGVVAPVAIGLGYPHPELLVLATGAGSVIFSHVNDGGFWLIKEYFNMTV
CCCCEEEEEECCCHHHHHHHHCCCCCCCEEEEEECCCCEEEEEECCCCEEEHHHHHHHHH
AQTFKTWTVLETLISIVAFALTVGLSYLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; gluconate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + gluconate [Periplasm] = Proton [Cytoplasm] + gluconate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA