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The map label for this gene is phoB [H]

Identifier: 77456868

GI number: 77456868

Start: 751742

End: 752551

Strand: Direct

Name: phoB [H]

Synonym: Pfl01_0640

Alternate gene names: 77456868

Gene position: 751742-752551 (Clockwise)

Preceding gene: 77456867

Following gene: 77456878

Centisome position: 11.68

GC content: 59.88

Gene sequence:

>810_bases
ATGGTCAGCTTTGGCCCGGGCATGGAGTGGCACGTGAACAAGCTTACGTCGGCGGTAAAAGTCCTTGTGGTCGATGATCA
GGCGCTGATCGTTGAAGAACTCTGTGAGTTTCTTGAGAGCAGCGGTTATCGCTGCGTGCCCTGTGAGTCCAGCAGCGAGG
CGGTCACGCGTTTCAGTGAAGACCCGGCCATCGGCCTGGTGTTGTGCGACCTGCACATGCCGGACATGGACGGCATCGAG
CTGGTGCAGGCGCTGCAGGGGGTGTCCGGCAAGAGCCGGGCGTTCGAAGCAATCATGCTTACCGGCCGCGCCGACAAGCA
GGATGTGATCAAGGCGTTGCGCGCGGGGATTGCCGATTACTACCAGAAACCGGTGGATCTGGATGAGTTGCTGGAGGGGT
TGCGGCGTCAGGAAACGGTGCTGCAGGAGCGGCAGAAGACCCTGCAACTGGGGCACCTGAATCAGAAGCTGCAGGATCTT
TCTTCGTCGATCGATGATTTGTATCAGGATCTGGACAAGGTTCGGCGCGGGCCTGCGCCGGCTGCCCAGACCGTGGCAGA
GGGTGACAGTGCAGAGATACCGGCGATTTTCGAGCAGTTGTCGCCGCGCCAGCTCGATGTGGCCCGGCTGGTGGGCAAGG
GGCAGACCAATTATCAGATTGCCTGTGAGTTGGGGATTACCGAGAACACGGTGAAGTTGTATGTGTCGCAGGTTTTGCGG
TTGACGCATATGCATAATCGGACGCAGCTGGCGTTGGCTCTGGCGCCGGGGAGTTCTTCTGCTGTTCGGCGGGGGGTTAC
GGCGCATTGA

Upstream 100 bases:

>100_bases
ATCCATTAGTCGCCACTCGCCACTACTGCTATGTACATAGTCGGAAAGTGCGTCTACTTTCAAATGAGCGGTTATACAGC
CATAGGCTGGCGGTACAGGA

Downstream 100 bases:

>100_bases
CCTTGGCGGCCTTTGGGCCGGCCAGGCCTTGGGTTTGTTTTGGGTGAATATCCGTTTCTTTGGGTGTTGCGGCTGGCGGT
TCCGCCCTTACGGCGGGTCA

Product: two component LuxR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 269; Mature: 269

Protein sequence:

>269_residues
MVSFGPGMEWHVNKLTSAVKVLVVDDQALIVEELCEFLESSGYRCVPCESSSEAVTRFSEDPAIGLVLCDLHMPDMDGIE
LVQALQGVSGKSRAFEAIMLTGRADKQDVIKALRAGIADYYQKPVDLDELLEGLRRQETVLQERQKTLQLGHLNQKLQDL
SSSIDDLYQDLDKVRRGPAPAAQTVAEGDSAEIPAIFEQLSPRQLDVARLVGKGQTNYQIACELGITENTVKLYVSQVLR
LTHMHNRTQLALALAPGSSSAVRRGVTAH

Sequences:

>Translated_269_residues
MVSFGPGMEWHVNKLTSAVKVLVVDDQALIVEELCEFLESSGYRCVPCESSSEAVTRFSEDPAIGLVLCDLHMPDMDGIE
LVQALQGVSGKSRAFEAIMLTGRADKQDVIKALRAGIADYYQKPVDLDELLEGLRRQETVLQERQKTLQLGHLNQKLQDL
SSSIDDLYQDLDKVRRGPAPAAQTVAEGDSAEIPAIFEQLSPRQLDVARLVGKGQTNYQIACELGITENTVKLYVSQVLR
LTHMHNRTQLALALAPGSSSAVRRGVTAH
>Mature_269_residues
MVSFGPGMEWHVNKLTSAVKVLVVDDQALIVEELCEFLESSGYRCVPCESSSEAVTRFSEDPAIGLVLCDLHMPDMDGIE
LVQALQGVSGKSRAFEAIMLTGRADKQDVIKALRAGIADYYQKPVDLDELLEGLRRQETVLQERQKTLQLGHLNQKLQDL
SSSIDDLYQDLDKVRRGPAPAAQTVAEGDSAEIPAIFEQLSPRQLDVARLVGKGQTNYQIACELGITENTVKLYVSQVLR
LTHMHNRTQLALALAPGSSSAVRRGVTAH

Specific function: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by phoB and phoR when phosphate is limited [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=114, Percent_Identity=35.0877192982456, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1788550, Length=143, Percent_Identity=30.0699300699301, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR011879
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 29527; Mature: 29527

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSFGPGMEWHVNKLTSAVKVLVVDDQALIVEELCEFLESSGYRCVPCESSSEAVTRFSE
CCCCCCCCCHHHHHHHHHHEEEEECCHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHCCC
DPAIGLVLCDLHMPDMDGIELVQALQGVSGKSRAFEAIMLTGRADKQDVIKALRAGIADY
CCCEEEEEEECCCCCCCHHHHHHHHHCCCCCHHHHHHHEECCCCCHHHHHHHHHHHHHHH
YQKPVDLDELLEGLRRQETVLQERQKTLQLGHLNQKLQDLSSSIDDLYQDLDKVRRGPAP
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
AAQTVAEGDSAEIPAIFEQLSPRQLDVARLVGKGQTNYQIACELGITENTVKLYVSQVLR
HHHHHHCCCCCCHHHHHHHCCCCHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHH
LTHMHNRTQLALALAPGSSSAVRRGVTAH
HHHHCCCCEEEEEECCCCHHHHHCCCCCC
>Mature Secondary Structure
MVSFGPGMEWHVNKLTSAVKVLVVDDQALIVEELCEFLESSGYRCVPCESSSEAVTRFSE
CCCCCCCCCHHHHHHHHHHEEEEECCHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHCCC
DPAIGLVLCDLHMPDMDGIELVQALQGVSGKSRAFEAIMLTGRADKQDVIKALRAGIADY
CCCEEEEEEECCCCCCCHHHHHHHHHCCCCCHHHHHHHEECCCCCHHHHHHHHHHHHHHH
YQKPVDLDELLEGLRRQETVLQERQKTLQLGHLNQKLQDLSSSIDDLYQDLDKVRRGPAP
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
AAQTVAEGDSAEIPAIFEQLSPRQLDVARLVGKGQTNYQIACELGITENTVKLYVSQVLR
HHHHHHCCCCCCHHHHHHHCCCCHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHH
LTHMHNRTQLALALAPGSSSAVRRGVTAH
HHHHCCCCEEEEEECCCCHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]