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The map label for this gene is fhuA [H]

Identifier: 77456822

GI number: 77456822

Start: 685671

End: 687797

Strand: Reverse

Name: fhuA [H]

Synonym: Pfl01_0594

Alternate gene names: 77456822

Gene position: 687797-685671 (Counterclockwise)

Preceding gene: 77456823

Following gene: 77456821

Centisome position: 10.68

GC content: 62.58

Gene sequence:

>2127_bases
ATGAACAAGTACCTCTTGTCCAGCCTCTGTCTGTTCGCCCTGAACCACAGCGCCCACGCCGACAACGCCCCGCTGACGCT
GCCCACCGGCACCATCACCGCCCTGGCCAATGACGACCAGACCGTCAGCCTGAGCACGCCAACCAGCGCCGGCTCGCGTC
TGAACCTCAGCGCCATGGAAACCCCGGCCAGTGTCGAAAGCCTGAGCGGCGAACAAGTCCGCGCCCGTGGCGATCGCAGC
GTGCAGGACGCGGTGTCGCGCAGCACCGGCATCAGCCGCACCGGCACGCCGGGCGATGGCGGCACCTCGTTGCAGGCCCG
GGGTTTTACCGGGCAGAGCTCGGTGATGCAGTTGTATGACGGCAACCGCCTGTACACCGGCATGGGCACCGTGACGTTCC
CGGTCGACACCTGGTCGGTAGAACGCGTCGATGTCCTGCGCGGCCCGGCCTCGGTGCTGTACGGCGAAGGCGCGACCGGC
GCGGTGGTCAACGTGATCCCGAAAAAGCCGTTCGAAGGCGAAATCGAAAACCACGTGCGCGTCGGTTACGGCTCGTTCGA
CCGCCAGCAGCAGGCGTTCGACAGCGGCGGCTCGCTGACCGACACCCTGAGCTATCGCCTCAACCTCAATCGCCTGCGCA
GCAACGGCTGGGTCGATCGCGGTGATTCGTCCAGCGACTTCATCAGCGCCGCCCTGCGCTGGCAGGCCACCGACGATCTG
AGTTTCACCCTCGCTCACGATTACGGCGATCAGCGCCCGCAGAACTACTTCGGTACGCCACTGATCAACGGCCAGTTGAA
GGACAGCCTGCGCAACAAGAACTACAACGTGCGCGACGACAAACAGCACTACAACGATCAATGGACGCGCCTGACCAGCG
ACTGGCAGATCAACGATGCAGTCAGCGCCAACAACGAGCTGTACTACCTCAAGGCCCAGCGCCGCTGGCAGAACGCCGAG
AACTACAACTTCGACGTTGACAGTCAGCAGCTCAGCCGCAGCGGCTACTTCGGTATCGGCCACCAACAGGAACAGGTCGG
CGACCGCCAGACCTTCACCTTCAAGCACTCGCTGTTCGGCCTCGACAGCCAGACCGTGACCGGCGTTGATTACAACCGCA
TTCGCTTCCAGCTCGACAGCAACTCGCCGTTCAACGACGTATTGCCGAACGGCCAGCCGCTGGATCGCTATCACCCGCAG
ACCGGCTATTTCGAGAGCGCCGATCCGTATCGCGATCAGTTCGACAGCACCACCAAACAGATGTCGGTGTTCGCCGAAAA
CCGCACGCAACTGAGCGAACGCTGGTCGCTGGTGACCGGTGTGCGCCGCGACTACGTACACGTGGATCGCAACAACCTGG
TCGACGGCAGCCAGAGCGACAAGACCCTGACCGGCAACAACTGGAAGGCCGGTCTGGTGTTCGCGCTGACCCAGGACACC
TCGTTCTACGGCCAGGTCGCCACCAGCACCGATGGCATCGGCGGTTTGATTTCCCTGAGCCCGAGCCAGCAGCAATATGA
CCTGTCGACCGCGCGGCAAACCGAGATCGGCCTGAAGCAGTTGTTCTGGGATCAGCGTGGTGAGTTCACCCTGGCGGCGT
ATCGCATCGTGAAGAAGAAGCTGCTGACTGACGACCCGGGCAACCCGACGCTCAAGCAGCAGGTCGGCCAGCAATCGTCG
AACGGTGTGGAGGCCAGCCTCGACCTGCAACTGCAGAACGCCTGGCAACTGCAAGCCAACGCTGCAATCGTGAAGGCCAA
GTACGACGATTTCGAAGAAGTGGTCGGTGGCGTGCCCGTGTCGCGCAACGGCAATCGCCCGGTGGACGTGCCACGCCGCA
CTGCCAATCTGTGGCTGAGCAAGGCGCTGACCGATGACCTGAAAGCCGGTGCCGGCGTGCGTTATGTCGATGCGCGCTAC
GCCGACATGGCCAACTGCAACGAGCTGCCGAGCTACACCGTGGTCGATGCAACGCTGTCGTGGAAAGCCCTGCGCAACAC
CACGCTGGGCTTGCAGGTGAACAATCTGTTTGACCGGACGTACGCGCAAAGCCAATACAATGAGGGCCAGCAGTGGATTC
TGGGTGAGCCTCGTTCGTTCTTTGTCACCGCTGACTACACCTTCTAG

Upstream 100 bases:

>100_bases
TTTAGTGTTACTGTATAACGCAAATTTGCTGCTCTGCCCGCAGCCATGCACTGTCATGAGGCTGCGGGCTTTTCTTTTGA
AGAAGTGATTCACCGTCCCG

Downstream 100 bases:

>100_bases
AACAGGAACGAAATGAGCTCACTGTCCCTCACCGATCTCGCCTGGACACCTCTGGGCCACGGCCATTGCCATCACCAGTT
CCAGCTGCGTGACGCCTCGT

Product: TonB-dependent siderophore receptor

Products: NA

Alternate protein names: Ferric hydroxamate receptor; Ferric hydroxamate uptake [H]

Number of amino acids: Translated: 708; Mature: 708

Protein sequence:

>708_residues
MNKYLLSSLCLFALNHSAHADNAPLTLPTGTITALANDDQTVSLSTPTSAGSRLNLSAMETPASVESLSGEQVRARGDRS
VQDAVSRSTGISRTGTPGDGGTSLQARGFTGQSSVMQLYDGNRLYTGMGTVTFPVDTWSVERVDVLRGPASVLYGEGATG
AVVNVIPKKPFEGEIENHVRVGYGSFDRQQQAFDSGGSLTDTLSYRLNLNRLRSNGWVDRGDSSSDFISAALRWQATDDL
SFTLAHDYGDQRPQNYFGTPLINGQLKDSLRNKNYNVRDDKQHYNDQWTRLTSDWQINDAVSANNELYYLKAQRRWQNAE
NYNFDVDSQQLSRSGYFGIGHQQEQVGDRQTFTFKHSLFGLDSQTVTGVDYNRIRFQLDSNSPFNDVLPNGQPLDRYHPQ
TGYFESADPYRDQFDSTTKQMSVFAENRTQLSERWSLVTGVRRDYVHVDRNNLVDGSQSDKTLTGNNWKAGLVFALTQDT
SFYGQVATSTDGIGGLISLSPSQQQYDLSTARQTEIGLKQLFWDQRGEFTLAAYRIVKKKLLTDDPGNPTLKQQVGQQSS
NGVEASLDLQLQNAWQLQANAAIVKAKYDDFEEVVGGVPVSRNGNRPVDVPRRTANLWLSKALTDDLKAGAGVRYVDARY
ADMANCNELPSYTVVDATLSWKALRNTTLGLQVNNLFDRTYAQSQYNEGQQWILGEPRSFFVTADYTF

Sequences:

>Translated_708_residues
MNKYLLSSLCLFALNHSAHADNAPLTLPTGTITALANDDQTVSLSTPTSAGSRLNLSAMETPASVESLSGEQVRARGDRS
VQDAVSRSTGISRTGTPGDGGTSLQARGFTGQSSVMQLYDGNRLYTGMGTVTFPVDTWSVERVDVLRGPASVLYGEGATG
AVVNVIPKKPFEGEIENHVRVGYGSFDRQQQAFDSGGSLTDTLSYRLNLNRLRSNGWVDRGDSSSDFISAALRWQATDDL
SFTLAHDYGDQRPQNYFGTPLINGQLKDSLRNKNYNVRDDKQHYNDQWTRLTSDWQINDAVSANNELYYLKAQRRWQNAE
NYNFDVDSQQLSRSGYFGIGHQQEQVGDRQTFTFKHSLFGLDSQTVTGVDYNRIRFQLDSNSPFNDVLPNGQPLDRYHPQ
TGYFESADPYRDQFDSTTKQMSVFAENRTQLSERWSLVTGVRRDYVHVDRNNLVDGSQSDKTLTGNNWKAGLVFALTQDT
SFYGQVATSTDGIGGLISLSPSQQQYDLSTARQTEIGLKQLFWDQRGEFTLAAYRIVKKKLLTDDPGNPTLKQQVGQQSS
NGVEASLDLQLQNAWQLQANAAIVKAKYDDFEEVVGGVPVSRNGNRPVDVPRRTANLWLSKALTDDLKAGAGVRYVDARY
ADMANCNELPSYTVVDATLSWKALRNTTLGLQVNNLFDRTYAQSQYNEGQQWILGEPRSFFVTADYTF
>Mature_708_residues
MNKYLLSSLCLFALNHSAHADNAPLTLPTGTITALANDDQTVSLSTPTSAGSRLNLSAMETPASVESLSGEQVRARGDRS
VQDAVSRSTGISRTGTPGDGGTSLQARGFTGQSSVMQLYDGNRLYTGMGTVTFPVDTWSVERVDVLRGPASVLYGEGATG
AVVNVIPKKPFEGEIENHVRVGYGSFDRQQQAFDSGGSLTDTLSYRLNLNRLRSNGWVDRGDSSSDFISAALRWQATDDL
SFTLAHDYGDQRPQNYFGTPLINGQLKDSLRNKNYNVRDDKQHYNDQWTRLTSDWQINDAVSANNELYYLKAQRRWQNAE
NYNFDVDSQQLSRSGYFGIGHQQEQVGDRQTFTFKHSLFGLDSQTVTGVDYNRIRFQLDSNSPFNDVLPNGQPLDRYHPQ
TGYFESADPYRDQFDSTTKQMSVFAENRTQLSERWSLVTGVRRDYVHVDRNNLVDGSQSDKTLTGNNWKAGLVFALTQDT
SFYGQVATSTDGIGGLISLSPSQQQYDLSTARQTEIGLKQLFWDQRGEFTLAAYRIVKKKLLTDDPGNPTLKQQVGQQSS
NGVEASLDLQLQNAWQLQANAAIVKAKYDDFEEVVGGVPVSRNGNRPVDVPRRTANLWLSKALTDDLKAGAGVRYVDARY
ADMANCNELPSYTVVDATLSWKALRNTTLGLQVNNLFDRTYAQSQYNEGQQWILGEPRSFFVTADYTF

Specific function: This receptor binds the ferrichrome-iron ligand. It interacts with the tonB protein, which is responsible for energy coupling of the ferrichrome-promoted iron transport system. Acts as a receptor for bacteriophage T5 as well as T1, phi80 and colicin M. Bi

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1786344, Length=712, Percent_Identity=24.7191011235955, Blast_Score=152, Evalue=8e-38,
Organism=Escherichia coli, GI1787344, Length=773, Percent_Identity=24.1914618369987, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1787024, Length=397, Percent_Identity=26.448362720403, Blast_Score=95, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR010917
- InterPro:   IPR010105 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 78783; Mature: 78783

Theoretical pI: Translated: 5.30; Mature: 5.30

Prosite motif: PS01156 TONB_DEPENDENT_REC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKYLLSSLCLFALNHSAHADNAPLTLPTGTITALANDDQTVSLSTPTSAGSRLNLSAME
CCHHHHHHHHHHHHCCCCCCCCCCEEECCCEEEEEECCCCEEEEECCCCCCCEEEEHHCC
TPASVESLSGEQVRARGDRSVQDAVSRSTGISRTGTPGDGGTSLQARGFTGQSSVMQLYD
CCCHHHHCCCCHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCCCHHHEEEC
GNRLYTGMGTVTFPVDTWSVERVDVLRGPASVLYGEGATGAVVNVIPKKPFEGEIENHVR
CCEEEECCCEEEEEECCCCCCHHHHHCCCCCEEECCCCCCCEEEECCCCCCCCCCCCCEE
VGYGSFDRQQQAFDSGGSLTDTLSYRLNLNRLRSNGWVDRGDSSSDFISAALRWQATDDL
ECCCCCHHHHHHHHCCCCEEEEEEEEEEHHHHHCCCCCCCCCCCHHHHHHHEEEECCCCC
SFTLAHDYGDQRPQNYFGTPLINGQLKDSLRNKNYNVRDDKQHYNDQWTRLTSDWQINDA
EEEEEECCCCCCCCCCCCCCEECCHHHHHHHCCCCCCCCCHHHHCCHHHEECCCCEECCC
VSANNELYYLKAQRRWQNAENYNFDVDSQQLSRSGYFGIGHQQEQVGDRQTFTFKHSLFG
CCCCCEEEEEEEHHHCCCCCCCCCCCCHHHHHCCCCCCCCCCHHHCCCCEEEEEEHHHCC
LDSQTVTGVDYNRIRFQLDSNSPFNDVLPNGQPLDRYHPQTGYFESADPYRDQFDSTTKQ
CCCCEEECCCEEEEEEEECCCCCHHHCCCCCCCCHHCCCCCCCCCCCCCHHHHHHHHHHH
MSVFAENRTQLSERWSLVTGVRRDYVHVDRNNLVDGSQSDKTLTGNNWKAGLVFALTQDT
HHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCEEECCCCCCEEEEEEECCC
SFYGQVATSTDGIGGLISLSPSQQQYDLSTARQTEIGLKQLFWDQRGEFTLAAYRIVKKK
CEEEEEECCCCCCCEEEEECCCCCHHCCHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHH
LLTDDPGNPTLKQQVGQQSSNGVEASLDLQLQNAWQLQANAAIVKAKYDDFEEVVGGVPV
HHCCCCCCCHHHHHHCCCCCCCCEEEEEEEECCCEEEECCEEEEEECCCCHHHHHCCCCC
SRNGNRPVDVPRRTANLWLSKALTDDLKAGAGVRYVDARYADMANCNELPSYTVVDATLS
CCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECHHHCCCCCCCCCCEEEEEEEEE
WKALRNTTLGLQVNNLFDRTYAQSQYNEGQQWILGEPRSFFVTADYTF
HHHHHCCEEEEEEHHHHHHHHHHHHHCCCCEEEECCCCEEEEEEECCC
>Mature Secondary Structure
MNKYLLSSLCLFALNHSAHADNAPLTLPTGTITALANDDQTVSLSTPTSAGSRLNLSAME
CCHHHHHHHHHHHHCCCCCCCCCCEEECCCEEEEEECCCCEEEEECCCCCCCEEEEHHCC
TPASVESLSGEQVRARGDRSVQDAVSRSTGISRTGTPGDGGTSLQARGFTGQSSVMQLYD
CCCHHHHCCCCHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCCCHHHEEEC
GNRLYTGMGTVTFPVDTWSVERVDVLRGPASVLYGEGATGAVVNVIPKKPFEGEIENHVR
CCEEEECCCEEEEEECCCCCCHHHHHCCCCCEEECCCCCCCEEEECCCCCCCCCCCCCEE
VGYGSFDRQQQAFDSGGSLTDTLSYRLNLNRLRSNGWVDRGDSSSDFISAALRWQATDDL
ECCCCCHHHHHHHHCCCCEEEEEEEEEEHHHHHCCCCCCCCCCCHHHHHHHEEEECCCCC
SFTLAHDYGDQRPQNYFGTPLINGQLKDSLRNKNYNVRDDKQHYNDQWTRLTSDWQINDA
EEEEEECCCCCCCCCCCCCCEECCHHHHHHHCCCCCCCCCHHHHCCHHHEECCCCEECCC
VSANNELYYLKAQRRWQNAENYNFDVDSQQLSRSGYFGIGHQQEQVGDRQTFTFKHSLFG
CCCCCEEEEEEEHHHCCCCCCCCCCCCHHHHHCCCCCCCCCCHHHCCCCEEEEEEHHHCC
LDSQTVTGVDYNRIRFQLDSNSPFNDVLPNGQPLDRYHPQTGYFESADPYRDQFDSTTKQ
CCCCEEECCCEEEEEEEECCCCCHHHCCCCCCCCHHCCCCCCCCCCCCCHHHHHHHHHHH
MSVFAENRTQLSERWSLVTGVRRDYVHVDRNNLVDGSQSDKTLTGNNWKAGLVFALTQDT
HHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCEEECCCCCCEEEEEEECCC
SFYGQVATSTDGIGGLISLSPSQQQYDLSTARQTEIGLKQLFWDQRGEFTLAAYRIVKKK
CEEEEEECCCCCCCEEEEECCCCCHHCCHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHH
LLTDDPGNPTLKQQVGQQSSNGVEASLDLQLQNAWQLQANAAIVKAKYDDFEEVVGGVPV
HHCCCCCCCHHHHHHCCCCCCCCEEEEEEEECCCEEEECCEEEEEECCCCHHHHHCCCCC
SRNGNRPVDVPRRTANLWLSKALTDDLKAGAGVRYVDARYADMANCNELPSYTVVDATLS
CCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECHHHCCCCCCCCCCEEEEEEEEE
WKALRNTTLGLQVNNLFDRTYAQSQYNEGQQWILGEPRSFFVTADYTF
HHHHHCCEEEEEEHHHHHHHHHHHHHCCCCEEEECCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3079747; 8202364; 9278503; 2823072; 7515827; 8617231; 9856937; 9865695; 10850805 [H]