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The map label for this gene is hlyB [H]

Identifier: 77456757

GI number: 77456757

Start: 612657

End: 614678

Strand: Direct

Name: hlyB [H]

Synonym: Pfl01_0529

Alternate gene names: 77456757

Gene position: 612657-614678 (Clockwise)

Preceding gene: 77456756

Following gene: 77456760

Centisome position: 9.52

GC content: 63.75

Gene sequence:

>2022_bases
ATGCCTGTTGGACGGCATGACCTTTGCTGTGATTCTGTCTACAAGAGTGCCATCAAATTAATGGCGTCAGAAGTAGAGGG
ATTCAAAGTGTCAGCCGTTCTCTCACTGTTACAAAGCCGTTTGTTGCGGCCTGTGTTCGTTACCCTTGGTATCGCCCTTT
TGGTGCAGGTGCTGGTGGCCGTCGCCCTGACGCGGAGCACCGTCACCGCGCTGGAGGCCGATCTCGGCACTCGCCTGGGC
GCCGACAGCCAGAAGTTGTCAGGTGAGCTGGAGCAGGCCGGGCGTGAAGTCACGTCGAGTCTCGACAACCTCTCCTCGAG
TACCCGTCAGCGTCTTACCGCCGGTCTTTCCTCGCGTCTGAAGGAAGAGCAGGCGCAGCTGCGTGCGACGTTGGAAAAAG
ACCTGAAGGATTCAGCCAATGACATGGCCCAGTTGCTGGCCTCGGTGGCGCCCCGTGCCATGTGGGACAGCGACGTGCCG
ACCCTGTCCGAATTCGCCCGTCGGGCCCAGCGCAATCCCAACGTGCTGTTTGTGGTGTATGACGACGCCACCGGCCAGCA
TCTGACCCGCTACCTCAACCGCGAAAACCCGATCAACAAGGCCCTTTTGGAAAAAGGCCAGGGCGAGCGGGCGCTGGACA
AGGTGCTGGATGCGGCGAAGAACGATCCGTCGGTCTACTACCTGGAAGCCTCGATCAACCCCAATGGCGTGGAGATCGGC
AAGGTGTTGATGGGCGTCTCCACCGCTTCGGTTGAAACCGATCTGGCGGCGCTCGACCAGCGCTTCTCGGCGTTGATTGC
CAGCAGCGATCAACTGGTCGGCGACAGTCTCAAAGGTGCTGCTGCCGACAGTGCCACCGCCATGCAGGCTCGCCTGCAAT
CGGCGCAGTCCACGGCTGCCGAGATGAAAGCCAACACCACCAGTACCGTGCAGGATGCTGCTGCAACGCTGCGTTGGCGC
ATCGGCATGGGCCTGGCGCTGGTCGGGGCTGGGGTGCTGTTGCTGCTGGCCGTGGTGCTCGGTCATCGGGTCGTCAATCG
TCTGAAAATGCTGAATGCCGCCATGGATGATCTGGCAGCAGGCGAGGGCGATCTGACCAAGCGCGTGCAGATCAACAGCA
AGGACGAGATCGGCGACATGGCGTCGGCGGTCAACCGCTTTGTGGACAAGTTGCAGCCGATCGTGCGCGAGGCCGGGGAT
GTGGCTCAGCGTACCGGTGTGGAAATCGGCGCCATGACCCTGCGCAACGCCGGTGCCGATGCGGCGGCCGGGATGCAGCG
TGATGAAGTGGCCGAAAGTCTGCGGGCGCTGTCGCAAATGGCCGATGAAGCGCAATCGGAAAGCCATGCGATGCAGGCCG
CGTTGAAGCAGGTGGTGGATATTCGCCAGGCCACCGACGAGAACACTCGCACCTCGGCCAAGGTCGGCAGCCTGATCGAG
GCGCTGGCGGGGCAGGTCGATACCGGGGCGAAAGTCATCGAGCGGCTGGCGCAGCAGAGCGAGCAGATCGAGGTGGTGCT
GACGGTGATTCACGGCATCGCCGAGCAGACCAACCTGCTGGCGCTCAACGCGGCCATTGAAGCGGCCCGTGCTGGTGAGA
CCGGTCGCGGGTTTGCGGTGGTGGCGGATGAGGTCCGGGCGCTGGCGAGCAAGACCCAAAGCTCCACCGGCGATATTCAG
GCGCACATCGTGGCCTTGCAGCAGGGCGCCCGTGAAGCGGTCGAGGCAATCGGTCAGGCCGGGCGTCAGGCCAGCGAAGG
CTTGCTGGTGCTGCGTGACAGTGCGCGTTTGCAGCAGTCGGTGCAGGCGTCGGTCGAGCAGGTGCATGCGGCGATTGGCC
TGGCGACTCAGGCCGCGGCGCATCAGGCGCAAGGCGCGCAAGCTGTGCGTGGGCGCGTCGAGACGATTCATGCCCAGGCC
GAGAAAGCCGCTCAGGCCGTGGTCGAGACCACGGCCAGCGGCAAGGTGCTGGATGGTCTGGCGGCGCAGCTCAAGGCCAG
TCTGGGGCAGTTCCGGGCCTGA

Upstream 100 bases:

>100_bases
GCCCGGACCGCAACGAAACCATCGTGCTGCGTCATCCGTTCGCTTGATAAGTCGTTGATGTAAAAACACAAAGGCCCCTT
CATCGGGGCCTTTGTCGTTT

Downstream 100 bases:

>100_bases
TAGTCCGGGCAAAAAAAATCGCAGCCTCGGCTGCGATTTTTTTATCGGCTCAAATACATCCGGGTCGTCAGCAGATACAC
CGGCAATCCCGACACCACAA

Product: chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 673; Mature: 672

Protein sequence:

>673_residues
MPVGRHDLCCDSVYKSAIKLMASEVEGFKVSAVLSLLQSRLLRPVFVTLGIALLVQVLVAVALTRSTVTALEADLGTRLG
ADSQKLSGELEQAGREVTSSLDNLSSSTRQRLTAGLSSRLKEEQAQLRATLEKDLKDSANDMAQLLASVAPRAMWDSDVP
TLSEFARRAQRNPNVLFVVYDDATGQHLTRYLNRENPINKALLEKGQGERALDKVLDAAKNDPSVYYLEASINPNGVEIG
KVLMGVSTASVETDLAALDQRFSALIASSDQLVGDSLKGAAADSATAMQARLQSAQSTAAEMKANTTSTVQDAAATLRWR
IGMGLALVGAGVLLLLAVVLGHRVVNRLKMLNAAMDDLAAGEGDLTKRVQINSKDEIGDMASAVNRFVDKLQPIVREAGD
VAQRTGVEIGAMTLRNAGADAAAGMQRDEVAESLRALSQMADEAQSESHAMQAALKQVVDIRQATDENTRTSAKVGSLIE
ALAGQVDTGAKVIERLAQQSEQIEVVLTVIHGIAEQTNLLALNAAIEAARAGETGRGFAVVADEVRALASKTQSSTGDIQ
AHIVALQQGAREAVEAIGQAGRQASEGLLVLRDSARLQQSVQASVEQVHAAIGLATQAAAHQAQGAQAVRGRVETIHAQA
EKAAQAVVETTASGKVLDGLAAQLKASLGQFRA

Sequences:

>Translated_673_residues
MPVGRHDLCCDSVYKSAIKLMASEVEGFKVSAVLSLLQSRLLRPVFVTLGIALLVQVLVAVALTRSTVTALEADLGTRLG
ADSQKLSGELEQAGREVTSSLDNLSSSTRQRLTAGLSSRLKEEQAQLRATLEKDLKDSANDMAQLLASVAPRAMWDSDVP
TLSEFARRAQRNPNVLFVVYDDATGQHLTRYLNRENPINKALLEKGQGERALDKVLDAAKNDPSVYYLEASINPNGVEIG
KVLMGVSTASVETDLAALDQRFSALIASSDQLVGDSLKGAAADSATAMQARLQSAQSTAAEMKANTTSTVQDAAATLRWR
IGMGLALVGAGVLLLLAVVLGHRVVNRLKMLNAAMDDLAAGEGDLTKRVQINSKDEIGDMASAVNRFVDKLQPIVREAGD
VAQRTGVEIGAMTLRNAGADAAAGMQRDEVAESLRALSQMADEAQSESHAMQAALKQVVDIRQATDENTRTSAKVGSLIE
ALAGQVDTGAKVIERLAQQSEQIEVVLTVIHGIAEQTNLLALNAAIEAARAGETGRGFAVVADEVRALASKTQSSTGDIQ
AHIVALQQGAREAVEAIGQAGRQASEGLLVLRDSARLQQSVQASVEQVHAAIGLATQAAAHQAQGAQAVRGRVETIHAQA
EKAAQAVVETTASGKVLDGLAAQLKASLGQFRA
>Mature_672_residues
PVGRHDLCCDSVYKSAIKLMASEVEGFKVSAVLSLLQSRLLRPVFVTLGIALLVQVLVAVALTRSTVTALEADLGTRLGA
DSQKLSGELEQAGREVTSSLDNLSSSTRQRLTAGLSSRLKEEQAQLRATLEKDLKDSANDMAQLLASVAPRAMWDSDVPT
LSEFARRAQRNPNVLFVVYDDATGQHLTRYLNRENPINKALLEKGQGERALDKVLDAAKNDPSVYYLEASINPNGVEIGK
VLMGVSTASVETDLAALDQRFSALIASSDQLVGDSLKGAAADSATAMQARLQSAQSTAAEMKANTTSTVQDAAATLRWRI
GMGLALVGAGVLLLLAVVLGHRVVNRLKMLNAAMDDLAAGEGDLTKRVQINSKDEIGDMASAVNRFVDKLQPIVREAGDV
AQRTGVEIGAMTLRNAGADAAAGMQRDEVAESLRALSQMADEAQSESHAMQAALKQVVDIRQATDENTRTSAKVGSLIEA
LAGQVDTGAKVIERLAQQSEQIEVVLTVIHGIAEQTNLLALNAAIEAARAGETGRGFAVVADEVRALASKTQSSTGDIQA
HIVALQQGAREAVEAIGQAGRQASEGLLVLRDSARLQQSVQASVEQVHAAIGLATQAAAHQAQGAQAVRGRVETIHAQAE
KAAQAVVETTASGKVLDGLAAQLKASLGQFRA

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788194, Length=235, Percent_Identity=31.063829787234, Blast_Score=87, Evalue=5e-18,
Organism=Escherichia coli, GI1788195, Length=206, Percent_Identity=35.9223300970874, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1787690, Length=253, Percent_Identity=30.8300395256917, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI2367378, Length=249, Percent_Identity=31.3253012048193, Blast_Score=83, Evalue=6e-17,
Organism=Escherichia coli, GI1789453, Length=260, Percent_Identity=29.6153846153846, Blast_Score=79, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 70884; Mature: 70753

Theoretical pI: Translated: 5.46; Mature: 5.46

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVGRHDLCCDSVYKSAIKLMASEVEGFKVSAVLSLLQSRLLRPVFVTLGIALLVQVLVA
CCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VALTRSTVTALEADLGTRLGADSQKLSGELEQAGREVTSSLDNLSSSTRQRLTAGLSSRL
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KEEQAQLRATLEKDLKDSANDMAQLLASVAPRAMWDSDVPTLSEFARRAQRNPNVLFVVY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCHHHHHHHHHCCCCCEEEEEE
DDATGQHLTRYLNRENPINKALLEKGQGERALDKVLDAAKNDPSVYYLEASINPNGVEIG
CCCCHHHHHHHHCCCCCHHHHHHHCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHH
KVLMGVSTASVETDLAALDQRFSALIASSDQLVGDSLKGAAADSATAMQARLQSAQSTAA
HHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHH
EMKANTTSTVQDAAATLRWRIGMGLALVGAGVLLLLAVVLGHRVVNRLKMLNAAMDDLAA
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GEGDLTKRVQINSKDEIGDMASAVNRFVDKLQPIVREAGDVAQRTGVEIGAMTLRNAGAD
CCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCH
AAAGMQRDEVAESLRALSQMADEAQSESHAMQAALKQVVDIRQATDENTRTSAKVGSLIE
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
ALAGQVDTGAKVIERLAQQSEQIEVVLTVIHGIAEQTNLLALNAAIEAARAGETGRGFAV
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
VADEVRALASKTQSSTGDIQAHIVALQQGAREAVEAIGQAGRQASEGLLVLRDSARLQQS
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHCCEEEEECHHHHHHH
VQASVEQVHAAIGLATQAAAHQAQGAQAVRGRVETIHAQAEKAAQAVVETTASGKVLDGL
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
AAQLKASLGQFRA
HHHHHHHHHHCCC
>Mature Secondary Structure 
PVGRHDLCCDSVYKSAIKLMASEVEGFKVSAVLSLLQSRLLRPVFVTLGIALLVQVLVA
CCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VALTRSTVTALEADLGTRLGADSQKLSGELEQAGREVTSSLDNLSSSTRQRLTAGLSSRL
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KEEQAQLRATLEKDLKDSANDMAQLLASVAPRAMWDSDVPTLSEFARRAQRNPNVLFVVY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCHHHHHHHHHCCCCCEEEEEE
DDATGQHLTRYLNRENPINKALLEKGQGERALDKVLDAAKNDPSVYYLEASINPNGVEIG
CCCCHHHHHHHHCCCCCHHHHHHHCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHH
KVLMGVSTASVETDLAALDQRFSALIASSDQLVGDSLKGAAADSATAMQARLQSAQSTAA
HHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHH
EMKANTTSTVQDAAATLRWRIGMGLALVGAGVLLLLAVVLGHRVVNRLKMLNAAMDDLAA
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GEGDLTKRVQINSKDEIGDMASAVNRFVDKLQPIVREAGDVAQRTGVEIGAMTLRNAGAD
CCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCH
AAAGMQRDEVAESLRALSQMADEAQSESHAMQAALKQVVDIRQATDENTRTSAKVGSLIE
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
ALAGQVDTGAKVIERLAQQSEQIEVVLTVIHGIAEQTNLLALNAAIEAARAGETGRGFAV
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
VADEVRALASKTQSSTGDIQAHIVALQQGAREAVEAIGQAGRQASEGLLVLRDSARLQQS
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHCCEEEEECHHHHHHH
VQASVEQVHAAIGLATQAAAHQAQGAQAVRGRVETIHAQAEKAAQAVVETTASGKVLDGL
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
AAQLKASLGQFRA
HHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]