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The map label for this gene is hflX [H]

Identifier: 77456752

GI number: 77456752

Start: 606322

End: 607623

Strand: Direct

Name: hflX [H]

Synonym: Pfl01_0524

Alternate gene names: 77456752

Gene position: 606322-607623 (Clockwise)

Preceding gene: 77456751

Following gene: 77456753

Centisome position: 9.42

GC content: 60.06

Gene sequence:

>1302_bases
TTGTTCTTTGAGCGCCACGGTGGTGGTGAACGAGTCATCCTCGTTCACTTGGATGGACAGGACCCTGAGGCGCGCGAAGA
TCCGCAGGAGTTTCAGGAACTGGCAAATTCGGCTGGCGCCGAGACCGTTGCGTTTTTTAACGTGCCGCGTCATCGGCCAA
CCGCCAAATACCTGATTGGCAGCGGCAAGGTCGAGGAACTGCGCGACCTGGTCCACGCCGAAGAAGCCGATCTGGTGATC
TTCAATCACACCCTTACACCCAGTCAGGAACGTAACCTCGAACGTGTTTTCGAGTGTCGCGTGATCGACCGTACCGGTCT
GATTCTCGATATTTTCGCCCAACGCGCCCGTACCCATGAGGGCAAGCTCCAGGTCGAACTGGCCCAGCTTGACCACATGA
GCACCCGGCTGGTTCGCGGCTGGACTCACCTTGAGCGTCAGGGTGGCGGTATCGGCATGCGCGGCCCGGGTGAAACCCAG
CTCGAAACCGACCGGCGACTGCTGCGGGTTCGCCTGCGCCAGATCAAGCGGCGGCTGGAAAAAGTGCGCAGCCAGCGCGA
ACAGTCGCGTCGCGGCCGCTCGCGTGCGGATATCCCTACCGTTTCTCTGGTGGGATACACCAACGCCGGTAAATCCACGC
TGTTCAATAATGTGACGAAGTCCGAGGTGTACGCGGCTGACCAGCTGTTCGCCACGCTCGACCCGACCCTGCGCCGTCTG
GATCTGGACGACCTGGGGCCGATTGTCCTGGCCGACACCGTGGGCTTCATCCGCCACTTGCCGCACAAACTGGTCGAGGC
ATTTCGGTCTACGCTCGAAGAGTCGAGCAACTCCGACCTGCTGTTGCACGTGATCGATGCGGCCGAACCGGATCGCATGT
TGCAGATCGAGCAGGTGATGGTGGTGCTGGGCGAGATCGGTGCCCAGGACTTGCCGATCCTCGAGGTCTATAACAAACTC
GATTTGCTTGAAGGCGTTGAGCCACAAATCCAGCGCGATGAAAACGGCAAGCCCCAGCGGGTCTGGCTGTCGGCGCGTGA
TGGCACCGGTCTGGAATTGCTCGAGCAGGCGATTGCCGAGTTGTTGGGCAGCGACCTGTTCGTGGGGACCTTGCGCTTGC
CTCAACGGTTCGCGCGTCTGCGTGCGCAGTTCTTCGAACTGGGCGCGGTACAGAAAGAAGAACACGATGAAGAAGGGGTC
AGCTTGCTGGCCGTTCGATTGCCACGCTCGGAGCTCAATCGACTGGTGAGTCGTGAAGGCGTTGTGCCGACGGAGTTCAT
CGAGCAACACACTTTGCAATAA

Upstream 100 bases:

>100_bases
TATCTCTACAGTCGTGCCGGTTCGTCCAATTCGTCTGCCAAGCGCAACCGAATCCGAAGCAGGTGACGCTGAGCCAGGTA
ACGCCTGATAGGAGTCTCCT

Downstream 100 bases:

>100_bases
AAGCCTGACAAAGCGGTTGTGCCGCAACGGCAGGCATTCTGTAGCATTGGTCGGCGCGCCGTGGGTGCGTCTTTGCTTTA
TCAGATGGAGAGCGCTATGG

Product: HSR1-like GTP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 433; Mature: 433

Protein sequence:

>433_residues
MFFERHGGGERVILVHLDGQDPEAREDPQEFQELANSAGAETVAFFNVPRHRPTAKYLIGSGKVEELRDLVHAEEADLVI
FNHTLTPSQERNLERVFECRVIDRTGLILDIFAQRARTHEGKLQVELAQLDHMSTRLVRGWTHLERQGGGIGMRGPGETQ
LETDRRLLRVRLRQIKRRLEKVRSQREQSRRGRSRADIPTVSLVGYTNAGKSTLFNNVTKSEVYAADQLFATLDPTLRRL
DLDDLGPIVLADTVGFIRHLPHKLVEAFRSTLEESSNSDLLLHVIDAAEPDRMLQIEQVMVVLGEIGAQDLPILEVYNKL
DLLEGVEPQIQRDENGKPQRVWLSARDGTGLELLEQAIAELLGSDLFVGTLRLPQRFARLRAQFFELGAVQKEEHDEEGV
SLLAVRLPRSELNRLVSREGVVPTEFIEQHTLQ

Sequences:

>Translated_433_residues
MFFERHGGGERVILVHLDGQDPEAREDPQEFQELANSAGAETVAFFNVPRHRPTAKYLIGSGKVEELRDLVHAEEADLVI
FNHTLTPSQERNLERVFECRVIDRTGLILDIFAQRARTHEGKLQVELAQLDHMSTRLVRGWTHLERQGGGIGMRGPGETQ
LETDRRLLRVRLRQIKRRLEKVRSQREQSRRGRSRADIPTVSLVGYTNAGKSTLFNNVTKSEVYAADQLFATLDPTLRRL
DLDDLGPIVLADTVGFIRHLPHKLVEAFRSTLEESSNSDLLLHVIDAAEPDRMLQIEQVMVVLGEIGAQDLPILEVYNKL
DLLEGVEPQIQRDENGKPQRVWLSARDGTGLELLEQAIAELLGSDLFVGTLRLPQRFARLRAQFFELGAVQKEEHDEEGV
SLLAVRLPRSELNRLVSREGVVPTEFIEQHTLQ
>Mature_433_residues
MFFERHGGGERVILVHLDGQDPEAREDPQEFQELANSAGAETVAFFNVPRHRPTAKYLIGSGKVEELRDLVHAEEADLVI
FNHTLTPSQERNLERVFECRVIDRTGLILDIFAQRARTHEGKLQVELAQLDHMSTRLVRGWTHLERQGGGIGMRGPGETQ
LETDRRLLRVRLRQIKRRLEKVRSQREQSRRGRSRADIPTVSLVGYTNAGKSTLFNNVTKSEVYAADQLFATLDPTLRRL
DLDDLGPIVLADTVGFIRHLPHKLVEAFRSTLEESSNSDLLLHVIDAAEPDRMLQIEQVMVVLGEIGAQDLPILEVYNKL
DLLEGVEPQIQRDENGKPQRVWLSARDGTGLELLEQAIAELLGSDLFVGTLRLPQRFARLRAQFFELGAVQKEEHDEEGV
SLLAVRLPRSELNRLVSREGVVPTEFIEQHTLQ

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310133116, Length=226, Percent_Identity=37.6106194690265, Blast_Score=133, Evalue=4e-31,
Organism=Homo sapiens, GI310133118, Length=228, Percent_Identity=37.280701754386, Blast_Score=132, Evalue=4e-31,
Organism=Homo sapiens, GI310124269, Length=208, Percent_Identity=38.4615384615385, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI310124267, Length=208, Percent_Identity=38.4615384615385, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI310124171, Length=208, Percent_Identity=38.4615384615385, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI310124169, Length=208, Percent_Identity=38.4615384615385, Blast_Score=130, Evalue=2e-30,
Organism=Escherichia coli, GI1790615, Length=418, Percent_Identity=59.8086124401914, Blast_Score=494, Evalue=1e-141,
Organism=Caenorhabditis elegans, GI17561038, Length=379, Percent_Identity=28.2321899736148, Blast_Score=122, Evalue=3e-28,
Organism=Drosophila melanogaster, GI24650079, Length=325, Percent_Identity=33.2307692307692, Blast_Score=129, Evalue=3e-30,
Organism=Drosophila melanogaster, GI20129375, Length=137, Percent_Identity=38.6861313868613, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 49086; Mature: 49086

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFFERHGGGERVILVHLDGQDPEAREDPQEFQELANSAGAETVAFFNVPRHRPTAKYLIG
CCCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCHHHEEC
SGKVEELRDLVHAEEADLVIFNHTLTPSQERNLERVFECRVIDRTGLILDIFAQRARTHE
CCCHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHEECCCCHHHHHHHHHHHCCC
GKLQVELAQLDHMSTRLVRGWTHLERQGGGIGMRGPGETQLETDRRLLRVRLRQIKRRLE
CCEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
KVRSQREQSRRGRSRADIPTVSLVGYTNAGKSTLFNNVTKSEVYAADQLFATLDPTLRRL
HHHHHHHHHHCCCCCCCCCEEEEEEECCCCCHHHHHCCHHHHHHHHHHHHHHHCHHHHHC
DLDDLGPIVLADTVGFIRHLPHKLVEAFRSTLEESSNSDLLLHVIDAAEPDRMLQIEQVM
CHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHH
VVLGEIGAQDLPILEVYNKLDLLEGVEPQIQRDENGKPQRVWLSARDGTGLELLEQAIAE
HHHHHCCCCCCHHHHHHHHHHHHCCCCCHHCCCCCCCCCEEEEEECCCCCHHHHHHHHHH
LLGSDLFVGTLRLPQRFARLRAQFFELGAVQKEEHDEEGVSLLAVRLPRSELNRLVSREG
HHCCCCEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHCC
VVPTEFIEQHTLQ
CCCHHHHHHHCCC
>Mature Secondary Structure
MFFERHGGGERVILVHLDGQDPEAREDPQEFQELANSAGAETVAFFNVPRHRPTAKYLIG
CCCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCHHHEEC
SGKVEELRDLVHAEEADLVIFNHTLTPSQERNLERVFECRVIDRTGLILDIFAQRARTHE
CCCHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHEECCCCHHHHHHHHHHHCCC
GKLQVELAQLDHMSTRLVRGWTHLERQGGGIGMRGPGETQLETDRRLLRVRLRQIKRRLE
CCEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
KVRSQREQSRRGRSRADIPTVSLVGYTNAGKSTLFNNVTKSEVYAADQLFATLDPTLRRL
HHHHHHHHHHCCCCCCCCCEEEEEEECCCCCHHHHHCCHHHHHHHHHHHHHHHCHHHHHC
DLDDLGPIVLADTVGFIRHLPHKLVEAFRSTLEESSNSDLLLHVIDAAEPDRMLQIEQVM
CHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHH
VVLGEIGAQDLPILEVYNKLDLLEGVEPQIQRDENGKPQRVWLSARDGTGLELLEQAIAE
HHHHHCCCCCCHHHHHHHHHHHHCCCCCHHCCCCCCCCCEEEEEECCCCCHHHHHHHHHH
LLGSDLFVGTLRLPQRFARLRAQFFELGAVQKEEHDEEGVSLLAVRLPRSELNRLVSREG
HHCCCCEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHCC
VVPTEFIEQHTLQ
CCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8248183; 7610040; 9278503; 2020545; 3040675 [H]