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The map label for this gene is putA [H]

Identifier: 77456680

GI number: 77456680

Start: 514599

End: 518552

Strand: Reverse

Name: putA [H]

Synonym: Pfl01_0452

Alternate gene names: 77456680

Gene position: 518552-514599 (Counterclockwise)

Preceding gene: 77456685

Following gene: 77456679

Centisome position: 8.05

GC content: 63.13

Gene sequence:

>3954_bases
ATGGCTACCACCACCCTTGGGGTCAAACTTGACGACCCGACCCGCGAACGCCTGAAGGCCGCCGCAACCTCGATTGATCG
CACACCGCACTGGCTGATCAAGCAGGCAATTTTCAATTACCTGGAGAAACTCGAGGGTGGTGCAACCCTGACCGAGCTGA
ACGGTTTGACCGCCAAGGACGCCGACGACGCGGGCGAAGTCCATACCGATCACGCTCACCAATGCTTCCTCGAATTCGCC
GAAAGCATCCTGCCGCAATCGGTGCTGCGCGCCTCGATCACCGCCGCTTACCGACGCCCCGAGCCGGAAGTGGTGCCGAT
GCTGATCGAGCAGGCGCGCCTGCCGGCGCCGATGGCCGAAGCCACCAACAAACTCGCCGCAACCATCGCGGAAAAACTGC
GTAACCAGAAGAGTGCCGGCGGTCGTGCAGGTATTGTTCAGGGCCTGTTGCAGGAATTTTCCCTGTCGTCCCAGGAAGGC
GTGGCGCTGATGTGCCTGGCCGAAGCACTGCTGCGGATCCCGGACAAAGGCACTCGCGATGCGCTGATCCGCGACAAGAT
CAGCACCGGCAACTGGCAGCCGCACTTGGGCAACAGCCCGTCGCTGTTCGTCAACGCGGCGACCTGGGGTCTGCTGCTGA
CCGGCAAACTGGTTTCCACTCACAACGAAGCCGGCCTGACTTCGTCCCTGAGCCGCATCATCGGCAAGAGCGGCGAGCCG
ATGATCCGCAAGGGCGTCGACATGGCCATGCGCCTGATGGGCGAGCAGTTCGTTACCGGCGAAACCATCGCCGAAGCCCT
GGCCAACGCGAGCAAGTTCGAAGCCAAGGGTTTCCGCTATTCCTACGACATGCTCGGTGAAGCGGCGCTGACCGAACACG
ACGCCCAGAAGTACCTGGCCTCGTACGAACAAGCCATTCACTCGATCGGCAAAGCGTCCCACGGCCGTGGGATTTATGAA
GGTCCGGGCATCTCGATCAAGCTGTCGGCCCTGCACCCGCGTTACAGCCGTGCCCAGTACGAGCGCGTGATGGACGAGCT
GTACCCGCGCCTGCTGTCGCTGACCCTGCTGGCCAAGCAATACGACATCGGCCTGAACATCGACGCCGAAGAAGCCGACC
GCCTGGAGCTGTCGCTGGATCTGCTCGAGCGTCTGTGCTTCGAGCCGCAACTGACCGGCTGGAACGGCATCGGTTTCGTG
ATCCAGGCCTACCAGAAGCGTTGCCCGTACGTGATCGACTACGTGATCGACCTGGCTCGCCGCAGCCGTCATCGCCTGAT
GATCCGTCTGGTGAAAGGCGCGTACTGGGACAGCGAAATCAAGCGCGCCCAGGTCGAAGGCCTGGAAGGCTATCCGGTCT
ACACCCGCAAGGTGTACACCGACGTTTCCTACATCGCCTGCGCCCGCAAACTGTTGTCGGTGCCGGAAGTCATTTACCCG
CAGTTCGCTACGCACAACGCCCACACCCTGTCGGCGATTTATCACATTGCCGGTCAGAACTATTACCCGGGCCAGTACGA
ATTCCAGTGCCTGCACGGCATGGGCGAACCGTTGTACGAACAGGTTGTAGGCAAGGTTTCCGAAGGCAAGCTGAACCGTC
CGTGCCGCGTGTACGCTCCGGTCGGCACCCACGAAACCCTGCTGGCGTACCTCGTACGTCGTCTGCTGGAAAACGGTGCC
AACACCTCGTTCGTCAACCGCATCGCCGACCAGTCGGTTTCGATTCAGGAGCTGGTGGCCGATCCGGTGGCACAGATCGA
GCAGATGGCGACCGTGGAAGGTGGTTTCGGCCTGCCGCACCCGCGCATCCCGCTGCCGCGTGACCTGTATGGCTCCGAGC
GCGCCAACTCTGCCGGCATCGACATGGCCAACGAACATCGTCTGGCGTCGCTGTCCTGCGCCCTGCTGGCCACCGCGCAC
AACAACTGGAAAGCCGCGCCGATGCTCGGTTGCGCCTCCAGCAACGAAGCGCCGGCACCGGTGCTGAACCCGTCCGATCT
GCGTGACGTGGTCGGCCATGTGCAGGAAGCCACGGTCGAAGACGTCGACAACGCCATTCAATGCGCCCTGAACGCCGCAC
CGATCTGGCAGGCCACCCCGCCGGCCGAACGTGCCGCGATTCTGGAACGTGCCGCTGACTTGATGGAAGGCGAGATCCAG
CCGCTGATGGGCCTGCTGGCCCGCGAAGCCGGCAAGACCTTCGCCAACGCCATCGCCGAAGTCCGCGAAGCCGTCGATTT
CCTGCGTTATTACGCGGTGCAGGCACGCAACGATTTCAGCAACGACGCCCACCGCCCACTGGGCCCGGTGGTGTGCATCA
GCCCATGGAACTTCCCGCTGGCGATCTTCAGCGGCCAAGTTGCCGCGGCACTGGCCGCCGGTAACCCGGTGCTGGCCAAA
CCGGCCGAACAGACTCCGCTGGTCGCCGCACAAGCCGTACGCCTGCTGCTCGAAGCCGGGATTCCGGAAGGCGTGCTGCA
ACTGCTGCCGGGTCGCGGTGAAACCGTCGGCGCCGGTCTGGTCGGCGATGAACGCGTCAAAGGCGTGATGTTCACCGGCT
CCACCGAAGTCGCGCGTCTGCTGCAACGCAACATCGCCGGTCGCCTCGACAACCAGGGCCGTCCGATTCCGCTGATCGCC
GAAACCGGCGGCCAGAACGCGATGATCGTCGACTCTTCGGCACTGACCGAACAGGTGGTGATCGACGTGGTGTCGTCGGC
CTTCGACAGCGCCGGTCAGCGTTGCTCGGCCCTGCGCGTCCTGTGCTTGCAGGAAGATTCCGCTGATCGCGTCATCGAAA
TGCTTAAAGGTGCGATGGCTGAAAGCCGTCTCGGCAACCCGGAGCGCCTGTCCGTGGACATCGGCCCGGTGATCGACGCC
GAAGCCAAGGCCGGCATCGAGAAGCACATCCAGGGCATGCGCGACAAAGGTCGCAACGTGTACCAGGTGGCTATTGCCGA
TACCGAGGAAGTCAAACGCGGCACCTTCGTCATGCCGACCCTGATCGAGCTGGAAAGCTTCGACGAACTGCAACGCGAGA
TCTTCGGCCCGGTGCTGCACGTGGTGCGCTACAAGCGTAAAGAGATCGACCAGTTGATCGCCCAGATCAACGCCTCCGGT
TACGGCCTGACCCTCGGCGTGCACACCCGCATCGACGAGACCATCGCCAAGGTGATCGACAACGTCAACGCCGGTAACGT
CTACGTCAACCGCAACATCGTGGGTGCCGTGGTCGGCGTCCAGCCATTCGGTGGTGAAGGCCTGTCGGGTACTGGCCCGA
AAGCCGGTGGCCCGCTGTACCTGTACCGTCTGCTGTCGACGCGTCCTACCGATGCCATCGAACAATCCTTCGCTCGCGCT
GATGCTGCCGTGGCGCCGGACGTTCGTCTGCGCGACGCCATGAGCAAACCGCTGACCGCTCTGAAAGCCTGGGCCGACAG
CAACAAGTTCGCCGACCTGAGCACCCTGTGCGTGCAGTACGCGGCGCAGTCGCAAAGCGGTATCACCCGCGTACTGGCCG
GCCCGACCGGCGAGAAGAACAGCTACGCGATCCTGCCGCGCGAGCACGTGCTGTGCCTGGCGGACATCGAAGGTGATCTG
CTGACCCAACTCGCTGCAGTACTGGCAGTAGGCGGTTCGGCAGTCTGGCCGGAATCCGACACCAGCAAGGCATTGTTCGC
ACGCCTGCCGAAGGAAATTCAGGCGCGAATCAAACTGGTTTCCGACTGGAACAAGGACGACGTGGTGTTCGACGCGGTTC
TGCATCACGGCCATTCCGACCAGTTGCGTGCGGTCTGCCAGCAGATCGCCAAGCGTGCCGGCGCCATCGTCGGGGTTCAG
GGCCTGTCCCAGGGCGAGACCAACATTGCACTGGAGCGTCTGGTGATCGAGCGTGCGTTGAGCGTCAACACCGCGGCAGC
AGGCGGCAACGCCAGTCTGATGACCATCGGTTAA

Upstream 100 bases:

>100_bases
CGACAAAAAAGGGTTGCACCCGGTTGCACCTGTTTCGGCTCGCGGCTAATCTTGCCGCCAGCTGTTGTCGCGCAACTGCG
GCACCTATGAGGATAAAAAT

Downstream 100 bases:

>100_bases
TCAGCAACTCTGTCAGCAACATAAAAATGGGCGCCCTCACCGGCGCCCATTTTTTTGGCCTCTCCATCACCGTTATCAAT
CTTCCTGTTCAGCCTTTATT

Product: trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase

Products: NA

Alternate protein names: Proline dehydrogenase; Proline oxidase; Delta-1-pyrroline-5-carboxylate dehydrogenase; P5C dehydrogenase [H]

Number of amino acids: Translated: 1317; Mature: 1316

Protein sequence:

>1317_residues
MATTTLGVKLDDPTRERLKAAATSIDRTPHWLIKQAIFNYLEKLEGGATLTELNGLTAKDADDAGEVHTDHAHQCFLEFA
ESILPQSVLRASITAAYRRPEPEVVPMLIEQARLPAPMAEATNKLAATIAEKLRNQKSAGGRAGIVQGLLQEFSLSSQEG
VALMCLAEALLRIPDKGTRDALIRDKISTGNWQPHLGNSPSLFVNAATWGLLLTGKLVSTHNEAGLTSSLSRIIGKSGEP
MIRKGVDMAMRLMGEQFVTGETIAEALANASKFEAKGFRYSYDMLGEAALTEHDAQKYLASYEQAIHSIGKASHGRGIYE
GPGISIKLSALHPRYSRAQYERVMDELYPRLLSLTLLAKQYDIGLNIDAEEADRLELSLDLLERLCFEPQLTGWNGIGFV
IQAYQKRCPYVIDYVIDLARRSRHRLMIRLVKGAYWDSEIKRAQVEGLEGYPVYTRKVYTDVSYIACARKLLSVPEVIYP
QFATHNAHTLSAIYHIAGQNYYPGQYEFQCLHGMGEPLYEQVVGKVSEGKLNRPCRVYAPVGTHETLLAYLVRRLLENGA
NTSFVNRIADQSVSIQELVADPVAQIEQMATVEGGFGLPHPRIPLPRDLYGSERANSAGIDMANEHRLASLSCALLATAH
NNWKAAPMLGCASSNEAPAPVLNPSDLRDVVGHVQEATVEDVDNAIQCALNAAPIWQATPPAERAAILERAADLMEGEIQ
PLMGLLAREAGKTFANAIAEVREAVDFLRYYAVQARNDFSNDAHRPLGPVVCISPWNFPLAIFSGQVAAALAAGNPVLAK
PAEQTPLVAAQAVRLLLEAGIPEGVLQLLPGRGETVGAGLVGDERVKGVMFTGSTEVARLLQRNIAGRLDNQGRPIPLIA
ETGGQNAMIVDSSALTEQVVIDVVSSAFDSAGQRCSALRVLCLQEDSADRVIEMLKGAMAESRLGNPERLSVDIGPVIDA
EAKAGIEKHIQGMRDKGRNVYQVAIADTEEVKRGTFVMPTLIELESFDELQREIFGPVLHVVRYKRKEIDQLIAQINASG
YGLTLGVHTRIDETIAKVIDNVNAGNVYVNRNIVGAVVGVQPFGGEGLSGTGPKAGGPLYLYRLLSTRPTDAIEQSFARA
DAAVAPDVRLRDAMSKPLTALKAWADSNKFADLSTLCVQYAAQSQSGITRVLAGPTGEKNSYAILPREHVLCLADIEGDL
LTQLAAVLAVGGSAVWPESDTSKALFARLPKEIQARIKLVSDWNKDDVVFDAVLHHGHSDQLRAVCQQIAKRAGAIVGVQ
GLSQGETNIALERLVIERALSVNTAAAGGNASLMTIG

Sequences:

>Translated_1317_residues
MATTTLGVKLDDPTRERLKAAATSIDRTPHWLIKQAIFNYLEKLEGGATLTELNGLTAKDADDAGEVHTDHAHQCFLEFA
ESILPQSVLRASITAAYRRPEPEVVPMLIEQARLPAPMAEATNKLAATIAEKLRNQKSAGGRAGIVQGLLQEFSLSSQEG
VALMCLAEALLRIPDKGTRDALIRDKISTGNWQPHLGNSPSLFVNAATWGLLLTGKLVSTHNEAGLTSSLSRIIGKSGEP
MIRKGVDMAMRLMGEQFVTGETIAEALANASKFEAKGFRYSYDMLGEAALTEHDAQKYLASYEQAIHSIGKASHGRGIYE
GPGISIKLSALHPRYSRAQYERVMDELYPRLLSLTLLAKQYDIGLNIDAEEADRLELSLDLLERLCFEPQLTGWNGIGFV
IQAYQKRCPYVIDYVIDLARRSRHRLMIRLVKGAYWDSEIKRAQVEGLEGYPVYTRKVYTDVSYIACARKLLSVPEVIYP
QFATHNAHTLSAIYHIAGQNYYPGQYEFQCLHGMGEPLYEQVVGKVSEGKLNRPCRVYAPVGTHETLLAYLVRRLLENGA
NTSFVNRIADQSVSIQELVADPVAQIEQMATVEGGFGLPHPRIPLPRDLYGSERANSAGIDMANEHRLASLSCALLATAH
NNWKAAPMLGCASSNEAPAPVLNPSDLRDVVGHVQEATVEDVDNAIQCALNAAPIWQATPPAERAAILERAADLMEGEIQ
PLMGLLAREAGKTFANAIAEVREAVDFLRYYAVQARNDFSNDAHRPLGPVVCISPWNFPLAIFSGQVAAALAAGNPVLAK
PAEQTPLVAAQAVRLLLEAGIPEGVLQLLPGRGETVGAGLVGDERVKGVMFTGSTEVARLLQRNIAGRLDNQGRPIPLIA
ETGGQNAMIVDSSALTEQVVIDVVSSAFDSAGQRCSALRVLCLQEDSADRVIEMLKGAMAESRLGNPERLSVDIGPVIDA
EAKAGIEKHIQGMRDKGRNVYQVAIADTEEVKRGTFVMPTLIELESFDELQREIFGPVLHVVRYKRKEIDQLIAQINASG
YGLTLGVHTRIDETIAKVIDNVNAGNVYVNRNIVGAVVGVQPFGGEGLSGTGPKAGGPLYLYRLLSTRPTDAIEQSFARA
DAAVAPDVRLRDAMSKPLTALKAWADSNKFADLSTLCVQYAAQSQSGITRVLAGPTGEKNSYAILPREHVLCLADIEGDL
LTQLAAVLAVGGSAVWPESDTSKALFARLPKEIQARIKLVSDWNKDDVVFDAVLHHGHSDQLRAVCQQIAKRAGAIVGVQ
GLSQGETNIALERLVIERALSVNTAAAGGNASLMTIG
>Mature_1316_residues
ATTTLGVKLDDPTRERLKAAATSIDRTPHWLIKQAIFNYLEKLEGGATLTELNGLTAKDADDAGEVHTDHAHQCFLEFAE
SILPQSVLRASITAAYRRPEPEVVPMLIEQARLPAPMAEATNKLAATIAEKLRNQKSAGGRAGIVQGLLQEFSLSSQEGV
ALMCLAEALLRIPDKGTRDALIRDKISTGNWQPHLGNSPSLFVNAATWGLLLTGKLVSTHNEAGLTSSLSRIIGKSGEPM
IRKGVDMAMRLMGEQFVTGETIAEALANASKFEAKGFRYSYDMLGEAALTEHDAQKYLASYEQAIHSIGKASHGRGIYEG
PGISIKLSALHPRYSRAQYERVMDELYPRLLSLTLLAKQYDIGLNIDAEEADRLELSLDLLERLCFEPQLTGWNGIGFVI
QAYQKRCPYVIDYVIDLARRSRHRLMIRLVKGAYWDSEIKRAQVEGLEGYPVYTRKVYTDVSYIACARKLLSVPEVIYPQ
FATHNAHTLSAIYHIAGQNYYPGQYEFQCLHGMGEPLYEQVVGKVSEGKLNRPCRVYAPVGTHETLLAYLVRRLLENGAN
TSFVNRIADQSVSIQELVADPVAQIEQMATVEGGFGLPHPRIPLPRDLYGSERANSAGIDMANEHRLASLSCALLATAHN
NWKAAPMLGCASSNEAPAPVLNPSDLRDVVGHVQEATVEDVDNAIQCALNAAPIWQATPPAERAAILERAADLMEGEIQP
LMGLLAREAGKTFANAIAEVREAVDFLRYYAVQARNDFSNDAHRPLGPVVCISPWNFPLAIFSGQVAAALAAGNPVLAKP
AEQTPLVAAQAVRLLLEAGIPEGVLQLLPGRGETVGAGLVGDERVKGVMFTGSTEVARLLQRNIAGRLDNQGRPIPLIAE
TGGQNAMIVDSSALTEQVVIDVVSSAFDSAGQRCSALRVLCLQEDSADRVIEMLKGAMAESRLGNPERLSVDIGPVIDAE
AKAGIEKHIQGMRDKGRNVYQVAIADTEEVKRGTFVMPTLIELESFDELQREIFGPVLHVVRYKRKEIDQLIAQINASGY
GLTLGVHTRIDETIAKVIDNVNAGNVYVNRNIVGAVVGVQPFGGEGLSGTGPKAGGPLYLYRLLSTRPTDAIEQSFARAD
AAVAPDVRLRDAMSKPLTALKAWADSNKFADLSTLCVQYAAQSQSGITRVLAGPTGEKNSYAILPREHVLCLADIEGDLL
TQLAAVLAVGGSAVWPESDTSKALFARLPKEIQARIKLVSDWNKDDVVFDAVLHHGHSDQLRAVCQQIAKRAGAIVGVQG
LSQGETNIALERLVIERALSVNTAAAGGNASLMTIG

Specific function: Oxidizes proline to glutamate for use as a carbon and nitrogen source and also function as a transcriptional repressor of the put operon [H]

COG id: COG4230

COG function: function code C; Delta 1-pyrroline-5-carboxylate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI21361176, Length=456, Percent_Identity=33.5526315789474, Blast_Score=199, Evalue=1e-50,
Organism=Homo sapiens, GI25777732, Length=456, Percent_Identity=32.8947368421053, Blast_Score=191, Evalue=3e-48,
Organism=Homo sapiens, GI25777724, Length=454, Percent_Identity=31.7180616740088, Blast_Score=188, Evalue=3e-47,
Organism=Homo sapiens, GI25777736, Length=451, Percent_Identity=33.9246119733925, Blast_Score=187, Evalue=8e-47,
Organism=Homo sapiens, GI25777734, Length=451, Percent_Identity=33.9246119733925, Blast_Score=187, Evalue=8e-47,
Organism=Homo sapiens, GI25777730, Length=456, Percent_Identity=32.8947368421053, Blast_Score=186, Evalue=9e-47,
Organism=Homo sapiens, GI238859541, Length=451, Percent_Identity=33.9246119733925, Blast_Score=186, Evalue=1e-46,
Organism=Homo sapiens, GI153266822, Length=452, Percent_Identity=30.5309734513274, Blast_Score=186, Evalue=1e-46,
Organism=Homo sapiens, GI25777728, Length=409, Percent_Identity=31.5403422982885, Blast_Score=167, Evalue=7e-41,
Organism=Homo sapiens, GI21614513, Length=421, Percent_Identity=30.6413301662708, Blast_Score=163, Evalue=1e-39,
Organism=Homo sapiens, GI238814322, Length=424, Percent_Identity=28.7735849056604, Blast_Score=157, Evalue=9e-38,
Organism=Homo sapiens, GI188035924, Length=446, Percent_Identity=29.5964125560538, Blast_Score=155, Evalue=3e-37,
Organism=Homo sapiens, GI12007648, Length=444, Percent_Identity=27.2522522522523, Blast_Score=155, Evalue=3e-37,
Organism=Homo sapiens, GI310128103, Length=446, Percent_Identity=29.5964125560538, Blast_Score=155, Evalue=4e-37,
Organism=Homo sapiens, GI310128093, Length=446, Percent_Identity=29.1479820627803, Blast_Score=154, Evalue=4e-37,
Organism=Homo sapiens, GI4507229, Length=418, Percent_Identity=28.4688995215311, Blast_Score=146, Evalue=1e-34,
Organism=Homo sapiens, GI25777721, Length=431, Percent_Identity=27.3781902552204, Blast_Score=136, Evalue=2e-31,
Organism=Homo sapiens, GI25777726, Length=454, Percent_Identity=27.7533039647577, Blast_Score=135, Evalue=3e-31,
Organism=Homo sapiens, GI25952152, Length=440, Percent_Identity=26.8181818181818, Blast_Score=132, Evalue=2e-30,
Organism=Homo sapiens, GI11095441, Length=429, Percent_Identity=27.5058275058275, Blast_Score=132, Evalue=3e-30,
Organism=Homo sapiens, GI115387104, Length=433, Percent_Identity=25.4041570438799, Blast_Score=129, Evalue=2e-29,
Organism=Homo sapiens, GI310128091, Length=446, Percent_Identity=28.2511210762332, Blast_Score=129, Evalue=2e-29,
Organism=Homo sapiens, GI310128087, Length=268, Percent_Identity=30.2238805970149, Blast_Score=105, Evalue=3e-22,
Organism=Homo sapiens, GI206597441, Length=442, Percent_Identity=27.3755656108597, Blast_Score=102, Evalue=2e-21,
Organism=Homo sapiens, GI206597439, Length=442, Percent_Identity=27.3755656108597, Blast_Score=102, Evalue=2e-21,
Organism=Homo sapiens, GI22907049, Length=442, Percent_Identity=27.3755656108597, Blast_Score=102, Evalue=2e-21,
Organism=Homo sapiens, GI71773324, Length=338, Percent_Identity=28.1065088757396, Blast_Score=102, Evalue=2e-21,
Organism=Homo sapiens, GI4502043, Length=422, Percent_Identity=27.4881516587678, Blast_Score=102, Evalue=3e-21,
Organism=Homo sapiens, GI238814371, Length=422, Percent_Identity=27.4881516587678, Blast_Score=102, Evalue=3e-21,
Organism=Homo sapiens, GI310128089, Length=327, Percent_Identity=29.0519877675841, Blast_Score=100, Evalue=8e-21,
Organism=Homo sapiens, GI310128095, Length=314, Percent_Identity=28.9808917197452, Blast_Score=94, Evalue=1e-18,
Organism=Homo sapiens, GI4557303, Length=337, Percent_Identity=26.1127596439169, Blast_Score=93, Evalue=2e-18,
Organism=Homo sapiens, GI73695881, Length=338, Percent_Identity=26.6272189349112, Blast_Score=93, Evalue=2e-18,
Organism=Homo sapiens, GI73695879, Length=338, Percent_Identity=26.6272189349112, Blast_Score=93, Evalue=2e-18,
Organism=Homo sapiens, GI73466520, Length=337, Percent_Identity=26.1127596439169, Blast_Score=92, Evalue=2e-18,
Organism=Homo sapiens, GI310128097, Length=259, Percent_Identity=31.2741312741313, Blast_Score=91, Evalue=7e-18,
Organism=Homo sapiens, GI310128101, Length=204, Percent_Identity=29.9019607843137, Blast_Score=86, Evalue=2e-16,
Organism=Homo sapiens, GI310128099, Length=204, Percent_Identity=29.9019607843137, Blast_Score=86, Evalue=2e-16,
Organism=Homo sapiens, GI301500698, Length=442, Percent_Identity=22.6244343891403, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI223972651, Length=430, Percent_Identity=26.5116279069767, Blast_Score=74, Evalue=1e-12,
Organism=Escherichia coli, GI1787250, Length=1322, Percent_Identity=73.6006051437216, Blast_Score=1988, Evalue=0.0,
Organism=Escherichia coli, GI1789015, Length=458, Percent_Identity=31.6593886462882, Blast_Score=185, Evalue=2e-47,
Organism=Escherichia coli, GI1787684, Length=457, Percent_Identity=30.1969365426696, Blast_Score=169, Evalue=1e-42,
Organism=Escherichia coli, GI1787715, Length=448, Percent_Identity=31.9196428571429, Blast_Score=166, Evalue=6e-42,
Organism=Escherichia coli, GI1788042, Length=441, Percent_Identity=30.8390022675737, Blast_Score=160, Evalue=7e-40,
Organism=Escherichia coli, GI1787558, Length=430, Percent_Identity=30.9302325581395, Blast_Score=159, Evalue=1e-39,
Organism=Escherichia coli, GI87081896, Length=460, Percent_Identity=30.2173913043478, Blast_Score=159, Evalue=2e-39,
Organism=Escherichia coli, GI1786504, Length=459, Percent_Identity=28.5403050108932, Blast_Score=150, Evalue=7e-37,
Organism=Escherichia coli, GI87082295, Length=435, Percent_Identity=30.5747126436782, Blast_Score=142, Evalue=2e-34,
Organism=Escherichia coli, GI87081926, Length=434, Percent_Identity=26.036866359447, Blast_Score=109, Evalue=1e-24,
Organism=Escherichia coli, GI1787653, Length=421, Percent_Identity=24.7030878859857, Blast_Score=80, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17534447, Length=482, Percent_Identity=33.402489626556, Blast_Score=203, Evalue=5e-52,
Organism=Caenorhabditis elegans, GI25144435, Length=454, Percent_Identity=31.7180616740088, Blast_Score=182, Evalue=1e-45,
Organism=Caenorhabditis elegans, GI17562198, Length=495, Percent_Identity=30.7070707070707, Blast_Score=180, Evalue=4e-45,
Organism=Caenorhabditis elegans, GI115534176, Length=482, Percent_Identity=30.9128630705394, Blast_Score=174, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI115532534, Length=399, Percent_Identity=32.3308270676692, Blast_Score=171, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI32564736, Length=410, Percent_Identity=31.9512195121951, Blast_Score=169, Evalue=7e-42,
Organism=Caenorhabditis elegans, GI133930964, Length=563, Percent_Identity=26.6429840142096, Blast_Score=161, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI32564151, Length=422, Percent_Identity=31.5165876777251, Blast_Score=160, Evalue=3e-39,
Organism=Caenorhabditis elegans, GI25143874, Length=438, Percent_Identity=29.2237442922374, Blast_Score=152, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI25143876, Length=438, Percent_Identity=29.2237442922374, Blast_Score=151, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI17551164, Length=449, Percent_Identity=25.6124721603563, Blast_Score=135, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI17534119, Length=455, Percent_Identity=28.5714285714286, Blast_Score=135, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI71986308, Length=426, Percent_Identity=26.056338028169, Blast_Score=127, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI71990744, Length=302, Percent_Identity=32.4503311258278, Blast_Score=120, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI71995606, Length=443, Percent_Identity=26.6365688487585, Blast_Score=119, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI71995613, Length=400, Percent_Identity=26, Blast_Score=112, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17564084, Length=333, Percent_Identity=26.4264264264264, Blast_Score=95, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI25146391, Length=331, Percent_Identity=25.0755287009063, Blast_Score=94, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI32566756, Length=331, Percent_Identity=25.0755287009063, Blast_Score=94, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI25146394, Length=331, Percent_Identity=25.0755287009063, Blast_Score=94, Evalue=6e-19,
Organism=Saccharomyces cerevisiae, GI6324950, Length=450, Percent_Identity=31.3333333333333, Blast_Score=191, Evalue=1e-48,
Organism=Saccharomyces cerevisiae, GI6325196, Length=459, Percent_Identity=32.4618736383442, Blast_Score=189, Evalue=2e-48,
Organism=Saccharomyces cerevisiae, GI6321826, Length=486, Percent_Identity=30.8641975308642, Blast_Score=187, Evalue=8e-48,
Organism=Saccharomyces cerevisiae, GI6320917, Length=461, Percent_Identity=31.0195227765727, Blast_Score=183, Evalue=2e-46,
Organism=Saccharomyces cerevisiae, GI6323822, Length=471, Percent_Identity=28.8747346072187, Blast_Score=164, Evalue=1e-40,
Organism=Saccharomyces cerevisiae, GI6323821, Length=473, Percent_Identity=29.5983086680761, Blast_Score=162, Evalue=3e-40,
Organism=Saccharomyces cerevisiae, GI6319478, Length=457, Percent_Identity=27.3522975929978, Blast_Score=141, Evalue=6e-34,
Organism=Saccharomyces cerevisiae, GI6321828, Length=505, Percent_Identity=23.5643564356436, Blast_Score=98, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6323757, Length=329, Percent_Identity=25.2279635258359, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI20129399, Length=455, Percent_Identity=32.5274725274725, Blast_Score=191, Evalue=4e-48,
Organism=Drosophila melanogaster, GI24668425, Length=475, Percent_Identity=29.0526315789474, Blast_Score=179, Evalue=1e-44,
Organism=Drosophila melanogaster, GI24668417, Length=475, Percent_Identity=29.0526315789474, Blast_Score=179, Evalue=1e-44,
Organism=Drosophila melanogaster, GI24668413, Length=475, Percent_Identity=29.0526315789474, Blast_Score=179, Evalue=1e-44,
Organism=Drosophila melanogaster, GI281362580, Length=458, Percent_Identity=29.0393013100437, Blast_Score=174, Evalue=4e-43,
Organism=Drosophila melanogaster, GI62472918, Length=458, Percent_Identity=29.0393013100437, Blast_Score=174, Evalue=4e-43,
Organism=Drosophila melanogaster, GI62472926, Length=458, Percent_Identity=29.0393013100437, Blast_Score=174, Evalue=4e-43,
Organism=Drosophila melanogaster, GI62472936, Length=458, Percent_Identity=29.0393013100437, Blast_Score=174, Evalue=4e-43,
Organism=Drosophila melanogaster, GI21356737, Length=458, Percent_Identity=29.0393013100437, Blast_Score=174, Evalue=4e-43,
Organism=Drosophila melanogaster, GI24650465, Length=452, Percent_Identity=30.0884955752212, Blast_Score=172, Evalue=2e-42,
Organism=Drosophila melanogaster, GI24585660, Length=459, Percent_Identity=28.1045751633987, Blast_Score=168, Evalue=2e-41,
Organism=Drosophila melanogaster, GI24666674, Length=457, Percent_Identity=30.4157549234136, Blast_Score=157, Evalue=6e-38,
Organism=Drosophila melanogaster, GI28571806, Length=498, Percent_Identity=28.5140562248996, Blast_Score=154, Evalue=3e-37,
Organism=Drosophila melanogaster, GI28571802, Length=498, Percent_Identity=28.5140562248996, Blast_Score=154, Evalue=3e-37,
Organism=Drosophila melanogaster, GI28571800, Length=498, Percent_Identity=28.5140562248996, Blast_Score=154, Evalue=3e-37,
Organism=Drosophila melanogaster, GI28571798, Length=498, Percent_Identity=28.5140562248996, Blast_Score=154, Evalue=3e-37,
Organism=Drosophila melanogaster, GI28571796, Length=498, Percent_Identity=28.5140562248996, Blast_Score=154, Evalue=3e-37,
Organism=Drosophila melanogaster, GI28571794, Length=498, Percent_Identity=28.5140562248996, Blast_Score=154, Evalue=3e-37,
Organism=Drosophila melanogaster, GI28574525, Length=465, Percent_Identity=27.9569892473118, Blast_Score=146, Evalue=1e-34,
Organism=Drosophila melanogaster, GI24638878, Length=416, Percent_Identity=25.7211538461538, Blast_Score=105, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24638876, Length=416, Percent_Identity=25.7211538461538, Blast_Score=105, Evalue=2e-22,
Organism=Drosophila melanogaster, GI281360299, Length=433, Percent_Identity=27.0207852193995, Blast_Score=100, Evalue=1e-20,
Organism=Drosophila melanogaster, GI281360297, Length=433, Percent_Identity=27.0207852193995, Blast_Score=100, Evalue=1e-20,
Organism=Drosophila melanogaster, GI281360295, Length=433, Percent_Identity=27.0207852193995, Blast_Score=100, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24586250, Length=433, Percent_Identity=27.0207852193995, Blast_Score=100, Evalue=1e-20,
Organism=Drosophila melanogaster, GI281360301, Length=428, Percent_Identity=26.8691588785047, Blast_Score=99, Evalue=2e-20,
Organism=Drosophila melanogaster, GI45552499, Length=432, Percent_Identity=25.9259259259259, Blast_Score=95, Evalue=3e-19,
Organism=Drosophila melanogaster, GI281360303, Length=428, Percent_Identity=25.9345794392523, Blast_Score=94, Evalue=6e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016160
- InterPro:   IPR016162
- InterPro:   IPR015590
- InterPro:   IPR005933
- InterPro:   IPR002872 [H]

Pfam domain/function: PF00171 Aldedh; PF01619 Pro_dh [H]

EC number: =1.5.99.8; =1.5.1.12 [H]

Molecular weight: Translated: 142593; Mature: 142461

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: PS00070 ALDEHYDE_DEHYDR_CYS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATTTLGVKLDDPTRERLKAAATSIDRTPHWLIKQAIFNYLEKLEGGATLTELNGLTAKD
CCCEEEEEEECCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCC
ADDAGEVHTDHAHQCFLEFAESILPQSVLRASITAAYRRPEPEVVPMLIEQARLPAPMAE
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCHHH
ATNKLAATIAEKLRNQKSAGGRAGIVQGLLQEFSLSSQEGVALMCLAEALLRIPDKGTRD
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCH
ALIRDKISTGNWQPHLGNSPSLFVNAATWGLLLTGKLVSTHNEAGLTSSLSRIIGKSGEP
HHHHHCCCCCCCCCCCCCCCCEEEEHHHHHHHEECHHHHCCCCCCHHHHHHHHHCCCCCH
MIRKGVDMAMRLMGEQFVTGETIAEALANASKFEAKGFRYSYDMLGEAALTEHDAQKYLA
HHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHCCCCEEEHHHHHHHHHHHHHHHHHHH
SYEQAIHSIGKASHGRGIYEGPGISIKLSALHPRYSRAQYERVMDELYPRLLSLTLLAKQ
HHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
YDIGLNIDAEEADRLELSLDLLERLCFEPQLTGWNGIGFVIQAYQKRCPYVIDYVIDLAR
HCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHH
RSRHRLMIRLVKGAYWDSEIKRAQVEGLEGYPVYTRKVYTDVSYIACARKLLSVPEVIYP
HHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHCCCHHHCC
QFATHNAHTLSAIYHIAGQNYYPGQYEFQCLHGMGEPLYEQVVGKVSEGKLNRPCRVYAP
CCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHCCCCHHHHHHHCCCCCCCCCCCEEEEEC
VGTHETLLAYLVRRLLENGANTSFVNRIADQSVSIQELVADPVAQIEQMATVEGGFGLPH
CCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCC
PRIPLPRDLYGSERANSAGIDMANEHRLASLSCALLATAHNNWKAAPMLGCASSNEAPAP
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHEECCCCCCCCCEEECCCCCCCCCC
VLNPSDLRDVVGHVQEATVEDVDNAIQCALNAAPIWQATPPAERAAILERAADLMEGEIQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCHHH
PLMGLLAREAGKTFANAIAEVREAVDFLRYYAVQARNDFSNDAHRPLGPVVCISPWNFPL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCCH
AIFSGQVAAALAAGNPVLAKPAEQTPLVAAQAVRLLLEAGIPEGVLQLLPGRGETVGAGL
HHHCCHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHCCCCCCEECCCC
VGDERVKGVMFTGSTEVARLLQRNIAGRLDNQGRPIPLIAETGGQNAMIVDSSALTEQVV
CCCHHCCEEEEECCHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCEEEEECHHHHHHHH
IDVVSSAFDSAGQRCSALRVLCLQEDSADRVIEMLKGAMAESRLGNPERLSVDIGPVIDA
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCC
EAKAGIEKHIQGMRDKGRNVYQVAIADTEEVKRGTFVMPTLIELESFDELQREIFGPVLH
HHHCCHHHHHHHHHHCCCCEEEEEECCHHHHCCCCEECHHHHHHHHHHHHHHHHHHHHHH
VVRYKRKEIDQLIAQINASGYGLTLGVHTRIDETIAKVIDNVNAGNVYVNRNIVGAVVGV
HHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHCCCCCCCEEEECCEEEEEEEC
QPFGGEGLSGTGPKAGGPLYLYRLLSTRPTDAIEQSFARADAAVAPDVRLRDAMSKPLTA
CCCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
LKAWADSNKFADLSTLCVQYAAQSQSGITRVLAGPTGEKNSYAILPREHVLCLADIEGDL
HHHHHCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCEEECCCCCEEEEECCCHHH
LTQLAAVLAVGGSAVWPESDTSKALFARLPKEIQARIKLVSDWNKDDVVFDAVLHHGHSD
HHHHHHHHHCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCCH
QLRAVCQQIAKRAGAIVGVQGLSQGETNIALERLVIERALSVNTAAAGGNASLMTIG
HHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEC
>Mature Secondary Structure 
ATTTLGVKLDDPTRERLKAAATSIDRTPHWLIKQAIFNYLEKLEGGATLTELNGLTAKD
CCEEEEEEECCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCC
ADDAGEVHTDHAHQCFLEFAESILPQSVLRASITAAYRRPEPEVVPMLIEQARLPAPMAE
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCHHH
ATNKLAATIAEKLRNQKSAGGRAGIVQGLLQEFSLSSQEGVALMCLAEALLRIPDKGTRD
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCH
ALIRDKISTGNWQPHLGNSPSLFVNAATWGLLLTGKLVSTHNEAGLTSSLSRIIGKSGEP
HHHHHCCCCCCCCCCCCCCCCEEEEHHHHHHHEECHHHHCCCCCCHHHHHHHHHCCCCCH
MIRKGVDMAMRLMGEQFVTGETIAEALANASKFEAKGFRYSYDMLGEAALTEHDAQKYLA
HHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHCCCCEEEHHHHHHHHHHHHHHHHHHH
SYEQAIHSIGKASHGRGIYEGPGISIKLSALHPRYSRAQYERVMDELYPRLLSLTLLAKQ
HHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
YDIGLNIDAEEADRLELSLDLLERLCFEPQLTGWNGIGFVIQAYQKRCPYVIDYVIDLAR
HCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHH
RSRHRLMIRLVKGAYWDSEIKRAQVEGLEGYPVYTRKVYTDVSYIACARKLLSVPEVIYP
HHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHCCCHHHCC
QFATHNAHTLSAIYHIAGQNYYPGQYEFQCLHGMGEPLYEQVVGKVSEGKLNRPCRVYAP
CCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHCCCCHHHHHHHCCCCCCCCCCCEEEEEC
VGTHETLLAYLVRRLLENGANTSFVNRIADQSVSIQELVADPVAQIEQMATVEGGFGLPH
CCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCC
PRIPLPRDLYGSERANSAGIDMANEHRLASLSCALLATAHNNWKAAPMLGCASSNEAPAP
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHEECCCCCCCCCEEECCCCCCCCCC
VLNPSDLRDVVGHVQEATVEDVDNAIQCALNAAPIWQATPPAERAAILERAADLMEGEIQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCHHH
PLMGLLAREAGKTFANAIAEVREAVDFLRYYAVQARNDFSNDAHRPLGPVVCISPWNFPL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCCH
AIFSGQVAAALAAGNPVLAKPAEQTPLVAAQAVRLLLEAGIPEGVLQLLPGRGETVGAGL
HHHCCHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHCCCCCCEECCCC
VGDERVKGVMFTGSTEVARLLQRNIAGRLDNQGRPIPLIAETGGQNAMIVDSSALTEQVV
CCCHHCCEEEEECCHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCEEEEECHHHHHHHH
IDVVSSAFDSAGQRCSALRVLCLQEDSADRVIEMLKGAMAESRLGNPERLSVDIGPVIDA
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCC
EAKAGIEKHIQGMRDKGRNVYQVAIADTEEVKRGTFVMPTLIELESFDELQREIFGPVLH
HHHCCHHHHHHHHHHCCCCEEEEEECCHHHHCCCCEECHHHHHHHHHHHHHHHHHHHHHH
VVRYKRKEIDQLIAQINASGYGLTLGVHTRIDETIAKVIDNVNAGNVYVNRNIVGAVVGV
HHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHCCCCCCCEEEECCEEEEEEEC
QPFGGEGLSGTGPKAGGPLYLYRLLSTRPTDAIEQSFARADAAVAPDVRLRDAMSKPLTA
CCCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
LKAWADSNKFADLSTLCVQYAAQSQSGITRVLAGPTGEKNSYAILPREHVLCLADIEGDL
HHHHHCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCEEECCCCCEEEEECCCHHH
LTQLAAVLAVGGSAVWPESDTSKALFARLPKEIQARIKLVSDWNKDDVVFDAVLHHGHSD
HHHHHHHHHCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCCH
QLRAVCQQIAKRAGAIVGVQGLSQGETNIALERLVIERALSVNTAAAGGNASLMTIG
HHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7966312; 8905232; 9278503; 3325781; 12514740 [H]