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The map label for this gene is hlyB [H]

Identifier: 77456675

GI number: 77456675

Start: 508115

End: 509740

Strand: Reverse

Name: hlyB [H]

Synonym: Pfl01_0447

Alternate gene names: 77456675

Gene position: 509740-508115 (Counterclockwise)

Preceding gene: 77456679

Following gene: 77456674

Centisome position: 7.92

GC content: 62.73

Gene sequence:

>1626_bases
ATGTCCCTTCGCAATATGAACATCGCCCCCCGGGCGTTCACCGGTTTCGCCCTGATCGGCGGCCTGATGCTGATTCTCGG
TGTGTTCGCCCTGAATCAGATGAGCAAGATCCGCGGCGCCGCCGAGGACATTTCCTCCAGCAGCGTGCCGAGCATCAAGA
ACCTCGACGAATTCACTCAGCTGACCCTGCGCCTGCGGGTGCTGTCGTACCGATTGCTGGTGAACCGCGAGCCGGACGTC
CAGCAGAAAACCATGGATCTGCTCGATATGCGCAACCAGCAGATCCGCAAGGCCCAGACCGATTACGAGCCGTTGATCGG
CAGCCCCGAAGAGCGTGCGGCCTACGACCAGTACGTGCAGTTGCTGGGTCAGTACCGCCAGATCGAAGACCGGATGAAAA
CCCTGTCGCGCAACAATCAGGTGGATGAGCTGCGCAACCTGCTGAACACCCAGTTGCTCGACAACTCCGAAGCGATCAAC
ACCGTGCTCAACCGCCTGATGCAGATCAACGGCCAGCAGATCAGCGAAACCAACCAGCAGGCCGCCGACCAGTATTCCTC
GGCCTTCAATCTGGTGGTGACCCTGCTGGTGATCGCCACCGGTCTGACCTTCCTGTTCGCCTGGTTGCTGACCGTCAGCA
TCACCAAGCCGATCGCCAAGGCTCTGGATGCAGCGGAAACCATCGCCGAAGGCAATCTGACCCAACCGATCCAAGTGGAC
GGCACCGACGAAGCCGGGCGCCTGCTGGCGGCCATGGCCAAGATGCAGTCGAAGCTGCGCGACACCCTGCAGCGGATTTC
CGGCTCGGCCACCCAACTGGCCTCCGCCGCCGAAGAGCTGAACAGCGTCACCGACGAAAGCGCCCGAGGCCTGACCCAGC
AGAACAACGAAATCGAGCAGGCCGCCACCGCCGTCAACGAAATGACCAGCGCCGTGGAAGAAGTTGCGCGCAACGCGGTC
AGCACCTCGGAAGCCTCGAAGAACGCCACCACCTCCGCCGGCGACGGCCGCGATCTGGTGCAGGAAACCGTCAGCGCCAT
CGAACGCATGAGCGCCGACGTGCAGAGCACCGCCACCCTGATCGGTGATCTGGCCAACGAATCCCGCGACATCGGCAAGG
TGCTGGACGTGATCCGTGGCCTGGCCGACCAGACCAACCTGCTGGCGCTCAACGCTGCAATTGAGGCGGCCCGCGCCGGT
GAAGCCGGTCGTGGATTTGCGGTGGTCGCCGACGAAGTTCGCGCCCTGGCGCACCGCACCCAGCAGTCGACCAGCGAAAT
CGAGCGCATGATTGGCAGCATCCAGAGCGGCACCGAACACGCCGTGGATTCGATGCGCAACAGCACCGAGCGCGCCGAAT
CGACCCTGAACATCGCCCGTGGTGCCGGCCTGTCGCTGGACACGATCAACACGGCCATCGTTGAAATCAACGAGCGCAAC
CTGGTGATCGCCAGCGCCGCCGAAGAGCAGGCGCAGGTGGCGCGGGAAGTGGATCGCAACCTGGTGAACATCCGCGATCT
GTCGGTGCAATCGGCGACCGGGGCGAATCAGACCAGTGCGGCGAGTAATGAGCTGTCGCGATTGGCGCTGGATCTGAACA
ATATGGTTGGGCGGTTTAGCCTGTAA

Upstream 100 bases:

>100_bases
AATACGCACACCACCTCAAGACTTTAGTCGTATGACCGATAAGTCACCCAACAGCAGTCTCAGCCCGCACGGATGCGGCC
CTTCCCTGGTATCCGCCTCC

Downstream 100 bases:

>100_bases
TTTTGAGATCAAGATCAAAAGCCCCCCTCACCCCAGCCCTCCCGAAACGTCGGACCGCCCCCAAGGGGGCGAGGGGGAAG
GGAGCAGATCGGGGGGCTTT

Product: chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 541; Mature: 540

Protein sequence:

>541_residues
MSLRNMNIAPRAFTGFALIGGLMLILGVFALNQMSKIRGAAEDISSSSVPSIKNLDEFTQLTLRLRVLSYRLLVNREPDV
QQKTMDLLDMRNQQIRKAQTDYEPLIGSPEERAAYDQYVQLLGQYRQIEDRMKTLSRNNQVDELRNLLNTQLLDNSEAIN
TVLNRLMQINGQQISETNQQAADQYSSAFNLVVTLLVIATGLTFLFAWLLTVSITKPIAKALDAAETIAEGNLTQPIQVD
GTDEAGRLLAAMAKMQSKLRDTLQRISGSATQLASAAEELNSVTDESARGLTQQNNEIEQAATAVNEMTSAVEEVARNAV
STSEASKNATTSAGDGRDLVQETVSAIERMSADVQSTATLIGDLANESRDIGKVLDVIRGLADQTNLLALNAAIEAARAG
EAGRGFAVVADEVRALAHRTQQSTSEIERMIGSIQSGTEHAVDSMRNSTERAESTLNIARGAGLSLDTINTAIVEINERN
LVIASAAEEQAQVAREVDRNLVNIRDLSVQSATGANQTSAASNELSRLALDLNNMVGRFSL

Sequences:

>Translated_541_residues
MSLRNMNIAPRAFTGFALIGGLMLILGVFALNQMSKIRGAAEDISSSSVPSIKNLDEFTQLTLRLRVLSYRLLVNREPDV
QQKTMDLLDMRNQQIRKAQTDYEPLIGSPEERAAYDQYVQLLGQYRQIEDRMKTLSRNNQVDELRNLLNTQLLDNSEAIN
TVLNRLMQINGQQISETNQQAADQYSSAFNLVVTLLVIATGLTFLFAWLLTVSITKPIAKALDAAETIAEGNLTQPIQVD
GTDEAGRLLAAMAKMQSKLRDTLQRISGSATQLASAAEELNSVTDESARGLTQQNNEIEQAATAVNEMTSAVEEVARNAV
STSEASKNATTSAGDGRDLVQETVSAIERMSADVQSTATLIGDLANESRDIGKVLDVIRGLADQTNLLALNAAIEAARAG
EAGRGFAVVADEVRALAHRTQQSTSEIERMIGSIQSGTEHAVDSMRNSTERAESTLNIARGAGLSLDTINTAIVEINERN
LVIASAAEEQAQVAREVDRNLVNIRDLSVQSATGANQTSAASNELSRLALDLNNMVGRFSL
>Mature_540_residues
SLRNMNIAPRAFTGFALIGGLMLILGVFALNQMSKIRGAAEDISSSSVPSIKNLDEFTQLTLRLRVLSYRLLVNREPDVQ
QKTMDLLDMRNQQIRKAQTDYEPLIGSPEERAAYDQYVQLLGQYRQIEDRMKTLSRNNQVDELRNLLNTQLLDNSEAINT
VLNRLMQINGQQISETNQQAADQYSSAFNLVVTLLVIATGLTFLFAWLLTVSITKPIAKALDAAETIAEGNLTQPIQVDG
TDEAGRLLAAMAKMQSKLRDTLQRISGSATQLASAAEELNSVTDESARGLTQQNNEIEQAATAVNEMTSAVEEVARNAVS
TSEASKNATTSAGDGRDLVQETVSAIERMSADVQSTATLIGDLANESRDIGKVLDVIRGLADQTNLLALNAAIEAARAGE
AGRGFAVVADEVRALAHRTQQSTSEIERMIGSIQSGTEHAVDSMRNSTERAESTLNIARGAGLSLDTINTAIVEINERNL
VIASAAEEQAQVAREVDRNLVNIRDLSVQSATGANQTSAASNELSRLALDLNNMVGRFSL

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=308, Percent_Identity=30.8441558441558, Blast_Score=143, Evalue=3e-35,
Organism=Escherichia coli, GI1788194, Length=352, Percent_Identity=31.8181818181818, Blast_Score=135, Evalue=5e-33,
Organism=Escherichia coli, GI1787690, Length=458, Percent_Identity=27.9475982532751, Blast_Score=130, Evalue=3e-31,
Organism=Escherichia coli, GI1788195, Length=524, Percent_Identity=27.6717557251908, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1789453, Length=336, Percent_Identity=29.4642857142857, Blast_Score=101, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 58596; Mature: 58464

Theoretical pI: Translated: 4.50; Mature: 4.50

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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C
>Mature Secondary Structure 
SLRNMNIAPRAFTGFALIGGLMLILGVFALNQMSKIRGAAEDISSSSVPSIKNLDEFTQ
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
LTLRLRVLSYRLLVNREPDVQQKTMDLLDMRNQQIRKAQTDYEPLIGSPEERAAYDQYVQ
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHH
LLGQYRQIEDRMKTLSRNNQVDELRNLLNTQLLDNSEAINTVLNRLMQINGQQISETNQQ
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHHHHHH
AADQYSSAFNLVVTLLVIATGLTFLFAWLLTVSITKPIAKALDAAETIAEGNLTQPIQVD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEC
GTDEAGRLLAAMAKMQSKLRDTLQRISGSATQLASAAEELNSVTDESARGLTQQNNEIEQ
CCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHCCHHHHH
AATAVNEMTSAVEEVARNAVSTSEASKNATTSAGDGRDLVQETVSAIERMSADVQSTATL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
IGDLANESRDIGKVLDVIRGLADQTNLLALNAAIEAARAGEAGRGFAVVADEVRALAHRT
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
QQSTSEIERMIGSIQSGTEHAVDSMRNSTERAESTLNIARGAGLSLDTINTAIVEINERN
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHEEECCCC
LVIASAAEEQAQVAREVDRNLVNIRDLSVQSATGANQTSAASNELSRLALDLNNMVGRFS
EEEEECHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
L
C

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]