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The map label for this gene is hlyB [H]

Identifier: 77456606

GI number: 77456606

Start: 433106

End: 435022

Strand: Reverse

Name: hlyB [H]

Synonym: Pfl01_0378

Alternate gene names: 77456606

Gene position: 435022-433106 (Counterclockwise)

Preceding gene: 77456607

Following gene: 77456585

Centisome position: 6.76

GC content: 63.59

Gene sequence:

>1917_bases
ATGTACCGTTGGTTAGCCGAGAGTCTTGGAAACGTCAGCGTCAAACGTAAGCTTGGAATCGGTTTCGGCCTGGTGCTGCT
GCTGACCCTGTTGATCACCTTCACCGGCTGGACCGGCATGAGCGGGATCATCAGCCGGGGTGACAAGCTCGGGTTCATCT
CCAGCCTCAACGAGCTGACCAAAGACCTGCGCCTGGCACGCCTGGACTATGAAGCCCGCCGTGGCGAACAGGGCCCTGGC
GCGGTCAACGACCTGCTCGGCAAGCTCGACAGCGGCCTGCAAAGCGCGCGCGGCATGATCGAGCAACCGTCCGACGTGGC
CATGATCGACCAGCAACTCGCGGCGGTCGCCGAGTACAAACGCGCCTTTGCCGACATGACCCAGGCCACCGTGCAGCGTG
AAGACGCCCGCAGCAAACTCGGCGCCAGCGCCGATAACGCCGTGGCCAAGGTCAGCGAAGTCGAGAAATCCCTGCTGCAA
GGCGACAGCGTTGCGCAATTCAACAGCGTGATCGAGCTGAGCAAACTGCTGCAGCAGGCGCGCTATCAGGTGCGCGGCTA
CACCTACAGCGGCAAGGCCGAAGCCGAACAACCGGCGCTGGATGCCATCGCCGCCGCCCTGAACAATCTGGAAAGCCTGC
CGAGCAAACTGCCCGAGCAACACATCGCCAACCTGCAACAGGCCACCGAATCGCTGAAGGCTTATCGCGCCGCCGTCAGC
CAGTTCCGCGACTCCCAGGTGAACAACGCGAAGGCCATGGCGCGAATGACCGCTCAGGGCGACATCCTGCTCGACGTCAG
CAAGAAACTTACCGAATCTCAGACCATCGTCCGCGACACCGATGCCGCGCACGCCAAAAACATGCTGATGATCGCCACCC
TGCTGGCCCTGGCCTTCGGTCTGCTGGCGGCCTGGGCGATCACCCGGCAGATCATCATTCCGCTGGAGCAAACCCTGAAA
GTCGCCGAGCGCGTGGCCGCCGGTGACCTGACCCACAATCTGGTATCCCTGCGCCGCGATGAACTTGGTCAACTGCAACG
CTCGATGCAGAGCATGACTCAGGGCCTGCGCGAATTGATCGGCGGCATCAGCGACGGCGTGACCCAGATCGCCAGCGCCG
CCGAAGAATTGTCCGCCGTGACCGAGCAGACCAGCGCCGGGGTCAACAATCAGAAAATCGAGACCGACCAGGTCGCCACC
GCCATGAACGAAATGGCCGCCACCGTGCAGGAAGTCGCGCGCAACGCCGAGGAAGCTTCGGAAGCCGCGGTCGCTGCTGA
TCAGCAGGCCCGTGAAGGCGACAAGGTGGTTGGCGAGGCGATCGCCCAGATCGAACGTCTGGCTGCCGAAGTCGGCCACT
CCACCGAGGCCATGGGCGAGCTCAAGCGCGAGAGCGACAAGATCGGCAGCGTGCTCGACGTGATCAAGTCCGTGGCTCAG
CAAACCAACCTGCTGGCCCTCAACGCCGCCATCGAGGCCGCCCGTGCCGGTGAAGCCGGACGTGGTTTTGCGGTGGTCGC
CGACGAAGTTCGCAGCCTCGCCCAGCGCACCCAGAAGTCCACCGAAGAGATCGAAGAGCTGATCGTCGGACTGCAGAACG
GCACCCAGCAAGTGGCAACGATCATGGACAACAGCCGCACCCTGACCGACAGCAGCGTCGAGCTGACCCGGCGTGCCGGT
GGTTCGCTGGAAAGCATCACCCGCACCGTTTCGGCGATTCAGGCGATGAACCAGCAGATCGCTGCGGCGGCCGAGCAGCA
GAGCGCTGTGGCTGAAGAGATCAACCGCAGCGTGCTGAACGTGCGGGATGTCTCGGACCAGACCTCGGCGGCCAGTGAAG
AGACAGCGGCCTCCAGCGTCGAGCTGGCGCGTTTGGGCACCCACCTGCAAACACTGGTGGGCCGGTTCAAGGTGTAA

Upstream 100 bases:

>100_bases
TGTTCTAAGCGCTTCGCCAGACAAAAGGCGTTACAGATTGCCATCATGCGGCCGATACACTCCCCATAAGTCCAATTAGT
GGTCCGAGGGGAGTCGTCGC

Downstream 100 bases:

>100_bases
ACCGCGCACACAAAAAAATCGCAGCCATTGGCTGCGATTTTTTTTGTCCTGCGTTTAGAGGACTTGCCGCAGGAACGCCT
GGGCTCGCGGATCCTTCGGT

Product: chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 638; Mature: 638

Protein sequence:

>638_residues
MYRWLAESLGNVSVKRKLGIGFGLVLLLTLLITFTGWTGMSGIISRGDKLGFISSLNELTKDLRLARLDYEARRGEQGPG
AVNDLLGKLDSGLQSARGMIEQPSDVAMIDQQLAAVAEYKRAFADMTQATVQREDARSKLGASADNAVAKVSEVEKSLLQ
GDSVAQFNSVIELSKLLQQARYQVRGYTYSGKAEAEQPALDAIAAALNNLESLPSKLPEQHIANLQQATESLKAYRAAVS
QFRDSQVNNAKAMARMTAQGDILLDVSKKLTESQTIVRDTDAAHAKNMLMIATLLALAFGLLAAWAITRQIIIPLEQTLK
VAERVAAGDLTHNLVSLRRDELGQLQRSMQSMTQGLRELIGGISDGVTQIASAAEELSAVTEQTSAGVNNQKIETDQVAT
AMNEMAATVQEVARNAEEASEAAVAADQQAREGDKVVGEAIAQIERLAAEVGHSTEAMGELKRESDKIGSVLDVIKSVAQ
QTNLLALNAAIEAARAGEAGRGFAVVADEVRSLAQRTQKSTEEIEELIVGLQNGTQQVATIMDNSRTLTDSSVELTRRAG
GSLESITRTVSAIQAMNQQIAAAAEQQSAVAEEINRSVLNVRDVSDQTSAASEETAASSVELARLGTHLQTLVGRFKV

Sequences:

>Translated_638_residues
MYRWLAESLGNVSVKRKLGIGFGLVLLLTLLITFTGWTGMSGIISRGDKLGFISSLNELTKDLRLARLDYEARRGEQGPG
AVNDLLGKLDSGLQSARGMIEQPSDVAMIDQQLAAVAEYKRAFADMTQATVQREDARSKLGASADNAVAKVSEVEKSLLQ
GDSVAQFNSVIELSKLLQQARYQVRGYTYSGKAEAEQPALDAIAAALNNLESLPSKLPEQHIANLQQATESLKAYRAAVS
QFRDSQVNNAKAMARMTAQGDILLDVSKKLTESQTIVRDTDAAHAKNMLMIATLLALAFGLLAAWAITRQIIIPLEQTLK
VAERVAAGDLTHNLVSLRRDELGQLQRSMQSMTQGLRELIGGISDGVTQIASAAEELSAVTEQTSAGVNNQKIETDQVAT
AMNEMAATVQEVARNAEEASEAAVAADQQAREGDKVVGEAIAQIERLAAEVGHSTEAMGELKRESDKIGSVLDVIKSVAQ
QTNLLALNAAIEAARAGEAGRGFAVVADEVRSLAQRTQKSTEEIEELIVGLQNGTQQVATIMDNSRTLTDSSVELTRRAG
GSLESITRTVSAIQAMNQQIAAAAEQQSAVAEEINRSVLNVRDVSDQTSAASEETAASSVELARLGTHLQTLVGRFKV
>Mature_638_residues
MYRWLAESLGNVSVKRKLGIGFGLVLLLTLLITFTGWTGMSGIISRGDKLGFISSLNELTKDLRLARLDYEARRGEQGPG
AVNDLLGKLDSGLQSARGMIEQPSDVAMIDQQLAAVAEYKRAFADMTQATVQREDARSKLGASADNAVAKVSEVEKSLLQ
GDSVAQFNSVIELSKLLQQARYQVRGYTYSGKAEAEQPALDAIAAALNNLESLPSKLPEQHIANLQQATESLKAYRAAVS
QFRDSQVNNAKAMARMTAQGDILLDVSKKLTESQTIVRDTDAAHAKNMLMIATLLALAFGLLAAWAITRQIIIPLEQTLK
VAERVAAGDLTHNLVSLRRDELGQLQRSMQSMTQGLRELIGGISDGVTQIASAAEELSAVTEQTSAGVNNQKIETDQVAT
AMNEMAATVQEVARNAEEASEAAVAADQQAREGDKVVGEAIAQIERLAAEVGHSTEAMGELKRESDKIGSVLDVIKSVAQ
QTNLLALNAAIEAARAGEAGRGFAVVADEVRSLAQRTQKSTEEIEELIVGLQNGTQQVATIMDNSRTLTDSSVELTRRAG
GSLESITRTVSAIQAMNQQIAAAAEQQSAVAEEINRSVLNVRDVSDQTSAASEETAASSVELARLGTHLQTLVGRFKV

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=352, Percent_Identity=33.8068181818182, Blast_Score=164, Evalue=2e-41,
Organism=Escherichia coli, GI2367378, Length=333, Percent_Identity=30.3303303303303, Blast_Score=143, Evalue=3e-35,
Organism=Escherichia coli, GI1788194, Length=362, Percent_Identity=32.0441988950276, Blast_Score=141, Evalue=2e-34,
Organism=Escherichia coli, GI1788195, Length=284, Percent_Identity=32.3943661971831, Blast_Score=134, Evalue=2e-32,
Organism=Escherichia coli, GI1789453, Length=331, Percent_Identity=29.3051359516616, Blast_Score=116, Evalue=6e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 68254; Mature: 68254

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYRWLAESLGNVSVKRKLGIGFGLVLLLTLLITFTGWTGMSGIISRGDKLGFISSLNELT
CCHHHHHHHCCCHHHHHHCCHHHHHHHHHHHHHHCCCCCCHHHHHCCCCHHHHHHHHHHH
KDLRLARLDYEARRGEQGPGAVNDLLGKLDSGLQSARGMIEQPSDVAMIDQQLAAVAEYK
HHHHHHHHCHHHHCCCCCCCHHHHHHHHHHHHHHHHCCHHCCCCHHHHHHHHHHHHHHHH
RAFADMTQATVQREDARSKLGASADNAVAKVSEVEKSLLQGDSVAQFNSVIELSKLLQQA
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
RYQVRGYTYSGKAEAEQPALDAIAAALNNLESLPSKLPEQHIANLQQATESLKAYRAAVS
HHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
QFRDSQVNNAKAMARMTAQGDILLDVSKKLTESQTIVRDTDAAHAKNMLMIATLLALAFG
HHHHHHCCHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
LLAAWAITRQIIIPLEQTLKVAERVAAGDLTHNLVSLRRDELGQLQRSMQSMTQGLRELI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GGISDGVTQIASAAEELSAVTEQTSAGVNNQKIETDQVATAMNEMAATVQEVARNAEEAS
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
EAAVAADQQAREGDKVVGEAIAQIERLAAEVGHSTEAMGELKRESDKIGSVLDVIKSVAQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
QTNLLALNAAIEAARAGEAGRGFAVVADEVRSLAQRTQKSTEEIEELIVGLQNGTQQVAT
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
IMDNSRTLTDSSVELTRRAGGSLESITRTVSAIQAMNQQIAAAAEQQSAVAEEINRSVLN
HHHCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VRDVSDQTSAASEETAASSVELARLGTHLQTLVGRFKV
HHCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MYRWLAESLGNVSVKRKLGIGFGLVLLLTLLITFTGWTGMSGIISRGDKLGFISSLNELT
CCHHHHHHHCCCHHHHHHCCHHHHHHHHHHHHHHCCCCCCHHHHHCCCCHHHHHHHHHHH
KDLRLARLDYEARRGEQGPGAVNDLLGKLDSGLQSARGMIEQPSDVAMIDQQLAAVAEYK
HHHHHHHHCHHHHCCCCCCCHHHHHHHHHHHHHHHHCCHHCCCCHHHHHHHHHHHHHHHH
RAFADMTQATVQREDARSKLGASADNAVAKVSEVEKSLLQGDSVAQFNSVIELSKLLQQA
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
RYQVRGYTYSGKAEAEQPALDAIAAALNNLESLPSKLPEQHIANLQQATESLKAYRAAVS
HHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
QFRDSQVNNAKAMARMTAQGDILLDVSKKLTESQTIVRDTDAAHAKNMLMIATLLALAFG
HHHHHHCCHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
LLAAWAITRQIIIPLEQTLKVAERVAAGDLTHNLVSLRRDELGQLQRSMQSMTQGLRELI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GGISDGVTQIASAAEELSAVTEQTSAGVNNQKIETDQVATAMNEMAATVQEVARNAEEAS
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
EAAVAADQQAREGDKVVGEAIAQIERLAAEVGHSTEAMGELKRESDKIGSVLDVIKSVAQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
QTNLLALNAAIEAARAGEAGRGFAVVADEVRSLAQRTQKSTEEIEELIVGLQNGTQQVAT
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
IMDNSRTLTDSSVELTRRAGGSLESITRTVSAIQAMNQQIAAAAEQQSAVAEEINRSVLN
HHHCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VRDVSDQTSAASEETAASSVELARLGTHLQTLVGRFKV
HHCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]