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The map label for this gene is fbp [H]

Identifier: 77456580

GI number: 77456580

Start: 402012

End: 403022

Strand: Direct

Name: fbp [H]

Synonym: Pfl01_0352

Alternate gene names: 77456580

Gene position: 402012-403022 (Clockwise)

Preceding gene: 77456579

Following gene: 77456581

Centisome position: 6.24

GC content: 59.94

Gene sequence:

>1011_bases
ATGTCCCGCGTTACCCTGAGTCGCTATTTGATTGAGCAGACCCGCAGCAACAACACTCCTGCCGATCTGCGTTTCCTGAT
CGAAGTGGTGGCGCGCGCCTGTAAAGAAATCAGCCACGCCGTGTCCAAAGGCGCCCTGGGCGGTGTTCTGGGCAGCATGG
GCACGGAAAACGTGCAAGGCGAAGTGCAGAAGAAGCTCGACGTGCTGTCGAACGAAATCCTGCTCGAAGCCAACGAATGG
GGCGGTCACCTGGCCGGCATGGCGTCCGAAGAAATGGACAACGCCTACCAGATCCCGGGCAAATACCCGAAAGGCGCCTA
CCTGCTGGTATTCGACCCGCTGGACGGTTCGTCGAACATCGACATCAACGCGCCGGTCGGCACCATCTTCTCCGTGCTGC
GTTGCCCGAACGAATACCTGAGCCAGAACGAAGCCCTGGATGAAAAGGCCTTCCTGCAGCCGGGCACTCAGCAAGTTGCC
GCCGGTTATGCCATCTATGGCCCGCAGACCATGCTGGTGCTGACCCTGGGCCACGGCGTCAAAGGCTTCACCCTGGACCG
CGAAATGGGCAGCTTCGTCCTGACCCACGAAGACATCACTATTCCTGAAAGCACCCAGGAATTCGCCATCAACATGTCCA
ACCAGCGTCATTGGGAAGCTCCGGTACAGCGCTACGTTTCGGAACTGCTGGCCGGTGAAGAAGGCCCGCTGAAAAAGAAC
TACAACATGCGTTGGGTCGCGGCGATGGTTGCCGATGTGCACCGCATCCTGACCCGTGGCGGTCTGTTCATGTACCCGCG
CGACAGCCGCGAGCCGTCCAAACCGGGCAAACTGCGCCTGATGTACGAAGCCAACCCGATGTCGTTCCTGGTGGAACAGG
CAGGCGGCGCTTCCACCGACGGTCACCAGCGCATTCTCGATATCAAGCCTGAAGGCCTGCACCAGCGCGTAGCGGTGTTC
CTCGGCTCGAAAGAAGAAGTCGCCCGCGCCACGGCGTACCACAAGGAATAA

Upstream 100 bases:

>100_bases
TTGCACCCGACGCACGTTACCGGGCGTCATTGCTCGCTACGGTTTCAGACTCCCTGTAAACTGCGCGGGTTTTTAGCCCC
CCATTCCACCGGAGCCGTCC

Downstream 100 bases:

>100_bases
ACCATGACCGCGCCCTGGCAGCCGTTGCTCGATTGGTGGTTCGGTCATGCCGAATCGGCTACTGAAGTGACGGCGCAACA
GGGCGGGTTGTGGTTCGGCA

Product: fructose-1,6-bisphosphatase

Products: NA

Alternate protein names: FBPase class 1; D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 [H]

Number of amino acids: Translated: 336; Mature: 335

Protein sequence:

>336_residues
MSRVTLSRYLIEQTRSNNTPADLRFLIEVVARACKEISHAVSKGALGGVLGSMGTENVQGEVQKKLDVLSNEILLEANEW
GGHLAGMASEEMDNAYQIPGKYPKGAYLLVFDPLDGSSNIDINAPVGTIFSVLRCPNEYLSQNEALDEKAFLQPGTQQVA
AGYAIYGPQTMLVLTLGHGVKGFTLDREMGSFVLTHEDITIPESTQEFAINMSNQRHWEAPVQRYVSELLAGEEGPLKKN
YNMRWVAAMVADVHRILTRGGLFMYPRDSREPSKPGKLRLMYEANPMSFLVEQAGGASTDGHQRILDIKPEGLHQRVAVF
LGSKEEVARATAYHKE

Sequences:

>Translated_336_residues
MSRVTLSRYLIEQTRSNNTPADLRFLIEVVARACKEISHAVSKGALGGVLGSMGTENVQGEVQKKLDVLSNEILLEANEW
GGHLAGMASEEMDNAYQIPGKYPKGAYLLVFDPLDGSSNIDINAPVGTIFSVLRCPNEYLSQNEALDEKAFLQPGTQQVA
AGYAIYGPQTMLVLTLGHGVKGFTLDREMGSFVLTHEDITIPESTQEFAINMSNQRHWEAPVQRYVSELLAGEEGPLKKN
YNMRWVAAMVADVHRILTRGGLFMYPRDSREPSKPGKLRLMYEANPMSFLVEQAGGASTDGHQRILDIKPEGLHQRVAVF
LGSKEEVARATAYHKE
>Mature_335_residues
SRVTLSRYLIEQTRSNNTPADLRFLIEVVARACKEISHAVSKGALGGVLGSMGTENVQGEVQKKLDVLSNEILLEANEWG
GHLAGMASEEMDNAYQIPGKYPKGAYLLVFDPLDGSSNIDINAPVGTIFSVLRCPNEYLSQNEALDEKAFLQPGTQQVAA
GYAIYGPQTMLVLTLGHGVKGFTLDREMGSFVLTHEDITIPESTQEFAINMSNQRHWEAPVQRYVSELLAGEEGPLKKNY
NMRWVAAMVADVHRILTRGGLFMYPRDSREPSKPGKLRLMYEANPMSFLVEQAGGASTDGHQRILDIKPEGLHQRVAVFL
GSKEEVARATAYHKE

Specific function: INVOLVED IN SEVERAL METABOLIC PATHWAYS. IN E.COLI AND YEAST IT IS NECESSARY FOR GROWTH ON SUBSTANCES SUCH AS GLYCEROL, SUCCINATE AND ACETATE. [C]

COG id: COG0158

COG function: function code G; Fructose-1,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FBPase class 1 family [H]

Homologues:

Organism=Homo sapiens, GI22907028, Length=324, Percent_Identity=41.9753086419753, Blast_Score=242, Evalue=5e-64,
Organism=Homo sapiens, GI189083692, Length=326, Percent_Identity=39.8773006134969, Blast_Score=226, Evalue=2e-59,
Organism=Homo sapiens, GI16579888, Length=326, Percent_Identity=39.8773006134969, Blast_Score=226, Evalue=2e-59,
Organism=Escherichia coli, GI1790679, Length=333, Percent_Identity=41.7417417417417, Blast_Score=256, Evalue=2e-69,
Organism=Caenorhabditis elegans, GI17508131, Length=331, Percent_Identity=41.0876132930514, Blast_Score=244, Evalue=4e-65,
Organism=Saccharomyces cerevisiae, GI6323409, Length=329, Percent_Identity=39.8176291793313, Blast_Score=240, Evalue=3e-64,
Organism=Drosophila melanogaster, GI45550998, Length=334, Percent_Identity=43.4131736526946, Blast_Score=239, Evalue=2e-63,
Organism=Drosophila melanogaster, GI19921562, Length=334, Percent_Identity=43.4131736526946, Blast_Score=239, Evalue=2e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000146 [H]

Pfam domain/function: PF00316 FBPase [H]

EC number: =3.1.3.11 [H]

Molecular weight: Translated: 37097; Mature: 36966

Theoretical pI: Translated: 5.85; Mature: 5.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRVTLSRYLIEQTRSNNTPADLRFLIEVVARACKEISHAVSKGALGGVLGSMGTENVQG
CCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
EVQKKLDVLSNEILLEANEWGGHLAGMASEEMDNAYQIPGKYPKGAYLLVFDPLDGSSNI
HHHHHHHHHCCCEEEEECCCCCHHCCCCHHHCCCEEECCCCCCCCEEEEEEECCCCCCCE
DINAPVGTIFSVLRCPNEYLSQNEALDEKAFLQPGTQQVAAGYAIYGPQTMLVLTLGHGV
EEECCHHHHHHHHHCCHHHHHCCCCCCHHHHCCCCHHHHHCCEEEECCCEEEEEEECCCC
KGFTLDREMGSFVLTHEDITIPESTQEFAINMSNQRHWEAPVQRYVSELLAGEEGPLKKN
CCEEECCCCCCEEEEECCCCCCCCCHHHEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCC
YNMRWVAAMVADVHRILTRGGLFMYPRDSREPSKPGKLRLMYEANPMSFLVEQAGGASTD
CCHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCEEEEEECCCHHHHHHHCCCCCCC
GHQRILDIKPEGLHQRVAVFLGSKEEVARATAYHKE
CCCEEEECCCCCHHHHHHHHCCCHHHHHHHHHCCCC
>Mature Secondary Structure 
SRVTLSRYLIEQTRSNNTPADLRFLIEVVARACKEISHAVSKGALGGVLGSMGTENVQG
CCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
EVQKKLDVLSNEILLEANEWGGHLAGMASEEMDNAYQIPGKYPKGAYLLVFDPLDGSSNI
HHHHHHHHHCCCEEEEECCCCCHHCCCCHHHCCCEEECCCCCCCCEEEEEEECCCCCCCE
DINAPVGTIFSVLRCPNEYLSQNEALDEKAFLQPGTQQVAAGYAIYGPQTMLVLTLGHGV
EEECCHHHHHHHHHCCHHHHHCCCCCCHHHHCCCCHHHHHCCEEEECCCEEEEEEECCCC
KGFTLDREMGSFVLTHEDITIPESTQEFAINMSNQRHWEAPVQRYVSELLAGEEGPLKKN
CCEEECCCCCCEEEEECCCCCCCCCHHHEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCC
YNMRWVAAMVADVHRILTRGGLFMYPRDSREPSKPGKLRLMYEANPMSFLVEQAGGASTD
CCHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCEEEEEECCCHHHHHHHCCCCCCC
GHQRILDIKPEGLHQRVAVFLGSKEEVARATAYHKE
CCCEEEECCCCCHHHHHHHHCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA