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The map label for this gene is oxlT [H]

Identifier: 77456550

GI number: 77456550

Start: 367689

End: 369353

Strand: Direct

Name: oxlT [H]

Synonym: Pfl01_0322

Alternate gene names: 77456550

Gene position: 367689-369353 (Clockwise)

Preceding gene: 77456545

Following gene: 77456551

Centisome position: 5.71

GC content: 62.7

Gene sequence:

>1665_bases
ATGAGCACGACCATTACGGCGGACGGCCTCAAAGCCGATCAGCCCGGGTTCCTGTCCAAGGAACGCATCATCGCCAAGCC
CGGTTTCAACCGTTGGCTGGTTCCACCGGCCGCTCTGGCCATTCACCTGTGCATCGGCATGGCCTACGGCTTCTCGGTGT
TCTGGTTGCCGCTGTCCAAGGCACTGGGCGTCACCGCTCCGGTGGCTTGCGCACCGGACATGAGCTTCATCGCACAAGTC
TTCTCGTCGCAATGTGACTGGCCGATCTCCATGCTCGGCTGGATCTACACCCTGTTCTTCATCTTCCTCGGCTGCTCGGC
AGCGATCTGGGGTGGCTGGCTTGAACACGCAGGACCACGCAAGGCCGGCGTTGTATCGGCATTGTGCTGGTGCGGCGGTC
TGCTGATTTCTGCGCTGGGTATCTATACCCACCAGATCTGGCTGATGTGGATCGGCTCCGGTGTGATCGGCGGTATCGGT
CTGGGTCTGGGCTACATCTCGCCGGTCTCGACCCTGATCAAGTGGTTCCCGGACAAGCGCGGCATGGCGACCGGCATGGC
GATCATGGGCTTCGGCGGTGGCGCGATGGTTGGTGCACCACTGGCGACCGCTCTGATGAGCCATTTCGCTTCGCCGACTG
GCGTGGGCGTGTGGCAGAGCTTCGTGGCCATGGCTGCGATCTACTTCGTGTTCATGATCGGTGGCGCGCTGGCTTACCGC
GTACCGCCAACCGGCTGGAAGCCTGAAGGCTGGACCGCGCCAGCGAAAAAAGCCTCGAACGCGATGATCACCCACCGTCA
CGTTCACGTGAATGTGGCGTGGAAAACCCCGCAATTCCGCCTGGTGTGGCTGGTGCTGTGCCTGAACGTGTCTGCCGGTA
TCGGCATCCTCGGCATGGCTTCGCCACTGTTGCAGGAAGTGTTCGGTGGCAAGCTGCTGGGCAACGATCTGCCGTTCGGT
CAGCTGGATGCCGGTCAACTGGCTTCCATCGCAGCGATTGCGGCCGGTTTCACCGGTCTGCTGAGCCTGTTCAACATCGG
CGGTCGCTTCTTCTGGGCGTCGTTCTCGGACTACCTGGGCCGCAAGAACACTTACTTCGTGTTCTTCGCACTGGGCTTTG
CGCTGTACGCACTGATCCCGAACCTCGGTCACCTGGGCAACGTTGCGCTGTTCGTGGCGGCGTTCTGCATCATCCTGTCG
ATGTACGGCGGCGGTTTCGCGACCGTGCCGGCGTATCTGGCCGACCTGTTCGGTACGCAGATGGTCGGCGCGATCCACGG
TCGTCTGCTGACGGCCTGGGCTGCCGCTGGCGTGCTGGGTCCGGTGCTGGTGAACTACCTGCGTGAGTATCAGCTGAGCA
TCGGCGTTGAACGCGCCGCCGCTTACGACATCACCCTGTACATCCTCGCCGGCCTGCTGGTGCTGGGCTTCCTGTGCAAC
CTGCTGGTGCGCCCGGTGGCGGACAAGTACTTCATGACTGACGCCGAACTGGCTGCCGAACAGGCGCTGGGTCACGACAA
GGGTGCTGATGGCAGCACCGTGCTGGAGTGGAAAGCCGCGCCGGGCAGCAAGCCGCTGGCGATCGCTGCGTGGCTGGTGG
TGGGAATTCCGTTGGCGTGGGGTGTGTGGGTGACCCTGCAGAAGACGGCGGTTCTGTTCCACTAA

Upstream 100 bases:

>100_bases
TTTCAAGGAGCTTCACCCGTAAAAAACGGTCATGCCTGCGTGCATAAAGGCCGGGGTGGGCAGTGGCTGGCGAACCATAC
TAATAATTGGGGGATACACA

Downstream 100 bases:

>100_bases
GTAACCGTTAAAACGCAGAACCCCTGTGGGAGCGGGCTTGCCCGCTCCCACATTTGTTTCCGGGTGCCTGTAATGGCTTG
TATGGACATGTCTACCCGCG

Product: major facilitator transporter

Products: NA

Alternate protein names: OFA; Oxalate:formate antiport protein; Oxalate:formate exchange protein [H]

Number of amino acids: Translated: 554; Mature: 553

Protein sequence:

>554_residues
MSTTITADGLKADQPGFLSKERIIAKPGFNRWLVPPAALAIHLCIGMAYGFSVFWLPLSKALGVTAPVACAPDMSFIAQV
FSSQCDWPISMLGWIYTLFFIFLGCSAAIWGGWLEHAGPRKAGVVSALCWCGGLLISALGIYTHQIWLMWIGSGVIGGIG
LGLGYISPVSTLIKWFPDKRGMATGMAIMGFGGGAMVGAPLATALMSHFASPTGVGVWQSFVAMAAIYFVFMIGGALAYR
VPPTGWKPEGWTAPAKKASNAMITHRHVHVNVAWKTPQFRLVWLVLCLNVSAGIGILGMASPLLQEVFGGKLLGNDLPFG
QLDAGQLASIAAIAAGFTGLLSLFNIGGRFFWASFSDYLGRKNTYFVFFALGFALYALIPNLGHLGNVALFVAAFCIILS
MYGGGFATVPAYLADLFGTQMVGAIHGRLLTAWAAAGVLGPVLVNYLREYQLSIGVERAAAYDITLYILAGLLVLGFLCN
LLVRPVADKYFMTDAELAAEQALGHDKGADGSTVLEWKAAPGSKPLAIAAWLVVGIPLAWGVWVTLQKTAVLFH

Sequences:

>Translated_554_residues
MSTTITADGLKADQPGFLSKERIIAKPGFNRWLVPPAALAIHLCIGMAYGFSVFWLPLSKALGVTAPVACAPDMSFIAQV
FSSQCDWPISMLGWIYTLFFIFLGCSAAIWGGWLEHAGPRKAGVVSALCWCGGLLISALGIYTHQIWLMWIGSGVIGGIG
LGLGYISPVSTLIKWFPDKRGMATGMAIMGFGGGAMVGAPLATALMSHFASPTGVGVWQSFVAMAAIYFVFMIGGALAYR
VPPTGWKPEGWTAPAKKASNAMITHRHVHVNVAWKTPQFRLVWLVLCLNVSAGIGILGMASPLLQEVFGGKLLGNDLPFG
QLDAGQLASIAAIAAGFTGLLSLFNIGGRFFWASFSDYLGRKNTYFVFFALGFALYALIPNLGHLGNVALFVAAFCIILS
MYGGGFATVPAYLADLFGTQMVGAIHGRLLTAWAAAGVLGPVLVNYLREYQLSIGVERAAAYDITLYILAGLLVLGFLCN
LLVRPVADKYFMTDAELAAEQALGHDKGADGSTVLEWKAAPGSKPLAIAAWLVVGIPLAWGVWVTLQKTAVLFH
>Mature_553_residues
STTITADGLKADQPGFLSKERIIAKPGFNRWLVPPAALAIHLCIGMAYGFSVFWLPLSKALGVTAPVACAPDMSFIAQVF
SSQCDWPISMLGWIYTLFFIFLGCSAAIWGGWLEHAGPRKAGVVSALCWCGGLLISALGIYTHQIWLMWIGSGVIGGIGL
GLGYISPVSTLIKWFPDKRGMATGMAIMGFGGGAMVGAPLATALMSHFASPTGVGVWQSFVAMAAIYFVFMIGGALAYRV
PPTGWKPEGWTAPAKKASNAMITHRHVHVNVAWKTPQFRLVWLVLCLNVSAGIGILGMASPLLQEVFGGKLLGNDLPFGQ
LDAGQLASIAAIAAGFTGLLSLFNIGGRFFWASFSDYLGRKNTYFVFFALGFALYALIPNLGHLGNVALFVAAFCIILSM
YGGGFATVPAYLADLFGTQMVGAIHGRLLTAWAAAGVLGPVLVNYLREYQLSIGVERAAAYDITLYILAGLLVLGFLCNL
LVRPVADKYFMTDAELAAEQALGHDKGADGSTVLEWKAAPGSKPLAIAAWLVVGIPLAWGVWVTLQKTAVLFH

Specific function: Anion transporter that carries out the exchange of divalent oxalate with monovalent formate, the product of oxalate decarboxylation, at the plasma membrane, and in doing so catalyzes the vectorial portion of a proton-motive metabolic cycle that drives ATP

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. OFA (TC 2.A.1.11) family [H]

Homologues:

Organism=Escherichia coli, GI1789969, Length=365, Percent_Identity=21.6438356164384, Blast_Score=83, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR004741 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 58900; Mature: 58769

Theoretical pI: Translated: 8.87; Mature: 8.87

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTTITADGLKADQPGFLSKERIIAKPGFNRWLVPPAALAIHLCIGMAYGFSVFWLPLSK
CCCEEECCCCCCCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ALGVTAPVACAPDMSFIAQVFSSQCDWPISMLGWIYTLFFIFLGCSAAIWGGWLEHAGPR
HCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
KAGVVSALCWCGGLLISALGIYTHQIWLMWIGSGVIGGIGLGLGYISPVSTLIKWFPDKR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
GMATGMAIMGFGGGAMVGAPLATALMSHFASPTGVGVWQSFVAMAAIYFVFMIGGALAYR
CCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCHHEEE
VPPTGWKPEGWTAPAKKASNAMITHRHVHVNVAWKTPQFRLVWLVLCLNVSAGIGILGMA
CCCCCCCCCCCCCCHHHCCCCEEEEEEEEEEEEECCCCHHHHHHHHHHHHCCCCCHHHHH
SPLLQEVFGGKLLGNDLPFGQLDAGQLASIAAIAAGFTGLLSLFNIGGRFFWASFSDYLG
HHHHHHHHCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECHHHHCC
RKNTYFVFFALGFALYALIPNLGHLGNVALFVAAFCIILSMYGGGFATVPAYLADLFGTQ
CCCCEEHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
MVGAIHGRLLTAWAAAGVLGPVLVNYLREYQLSIGVERAAAYDITLYILAGLLVLGFLCN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHH
LLVRPVADKYFMTDAELAAEQALGHDKGADGSTVLEWKAAPGSKPLAIAAWLVVGIPLAW
HHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHH
GVWVTLQKTAVLFH
HHHHEEEHHHEECC
>Mature Secondary Structure 
STTITADGLKADQPGFLSKERIIAKPGFNRWLVPPAALAIHLCIGMAYGFSVFWLPLSK
CCEEECCCCCCCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ALGVTAPVACAPDMSFIAQVFSSQCDWPISMLGWIYTLFFIFLGCSAAIWGGWLEHAGPR
HCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
KAGVVSALCWCGGLLISALGIYTHQIWLMWIGSGVIGGIGLGLGYISPVSTLIKWFPDKR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
GMATGMAIMGFGGGAMVGAPLATALMSHFASPTGVGVWQSFVAMAAIYFVFMIGGALAYR
CCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCHHEEE
VPPTGWKPEGWTAPAKKASNAMITHRHVHVNVAWKTPQFRLVWLVLCLNVSAGIGILGMA
CCCCCCCCCCCCCCHHHCCCCEEEEEEEEEEEEECCCCHHHHHHHHHHHHCCCCCHHHHH
SPLLQEVFGGKLLGNDLPFGQLDAGQLASIAAIAAGFTGLLSLFNIGGRFFWASFSDYLG
HHHHHHHHCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECHHHHCC
RKNTYFVFFALGFALYALIPNLGHLGNVALFVAAFCIILSMYGGGFATVPAYLADLFGTQ
CCCCEEHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
MVGAIHGRLLTAWAAAGVLGPVLVNYLREYQLSIGVERAAAYDITLYILAGLLVLGFLCN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHH
LLVRPVADKYFMTDAELAAEQALGHDKGADGSTVLEWKAAPGSKPLAIAAWLVVGIPLAW
HHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHH
GVWVTLQKTAVLFH
HHHHEEEHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8636101; 9651403; 11919184; 11113128; 11274108; 11500368 [H]