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The map label for this gene is oprD [H]

Identifier: 77456523

GI number: 77456523

Start: 344587

End: 345873

Strand: Direct

Name: oprD [H]

Synonym: Pfl01_0295

Alternate gene names: 77456523

Gene position: 344587-345873 (Clockwise)

Preceding gene: 77456522

Following gene: 77456524

Centisome position: 5.35

GC content: 58.2

Gene sequence:

>1287_bases
ATGTTGAACAAGCGAATCAGTTTGATCGCACTGGGGATGTTGAGTGCCACTTCGGCCATGGCTAACGACCAGGCCGAGTC
CAAGGGTTTTGTTGAAGACAGCAGTCTCAAAGTGCTGCTGCGCAATGCCTACATCAATCGTGACTACAAAGATGGCAACC
AGGACAAAGCCGAATGGGGCCAAGCGGCCATCGGTACGTTCTCGTCCGGTTTCACTCAAGGCACCGTCGGTGTCGGTGTG
GATGCCTTCGGTCTGTACGCGCTGCGTCTGGACGGCGGCAAGGGCCGCAGCGGTGCGGGCGGTATCGACTTCTTCAAGCG
CGGTGACAGCGGTAACGCGGCTGACGACCTGTCGAAGGGTGGCGCAGCGGTGAAATTCCGTATTTCCAACACCGTACTGA
CTTACGGTGACCAGATGCCGGCCCTGCCGGTGCTGAGCTACGACAACGTGCGTCTGCTGCCGGAAAGCTATACCGGTACC
CTGATCACTTCCAAAGAGATCAAAGGTCTGCAACTGGATGCCGGTCGTTTCACCGCCGAGTCGCGCAAGAGCGCTGAAGG
CCGTGACAGCGGCGGTCTGAAGTCGATCAACGTATTAGGCGGTAGCTACCAGTTCACCGAACAGTTCAAGGCTGCGCTGT
ACGCTTCCGACGTTGAAGACGTGCTGAAGAAACAATACGTGAACGCCAACTACGTGTTCCCGATCGACAAGGATCAGTCC
CTGACCCTGGACTTCAACGGTTACCGCACCAAGCTGGACAACTCCTACGTCCGCGAAAACGGTGTAACCGGCGACGACAA
CAAGATCTGGAGCCTGGCAGCGACCTTCGCCACCGGCCCGCACTCGTTCACCGTGGCGCACCAGCGCTCCACTGGCGACA
GCAACCTGGGTTACGCCTACGGCGGTTATCAGAAAGGTCAGGGTCGCGTGGGTGACGGTGGCAACACCATCTACCTGGCC
AACTCCTACTGGTCCGACTTCAACGCTGAAGACGAGCGCAGCTGGCAGTTGGGCTACGGCCTGGACTTCAGCGCATTCGG
CGTCCCGGGTCTGAGCTACAACTTCGCGTACGTGCGTGGCGACAACATCACCACGTCCACCAGCGAAGGCGGCACCGAGC
GCGAGATCTTCAATCAGTTCAAGTACGTCGTGCAAAGTGGCCCGGCCAAAGACCTGAGCATCAAGCTGCGTAGCTCGATC
CTGCGTGTTTCGCAGAAATCCAGCGAATACAACGTCAGCGGCAACGAACTGCGTGTGTTCGTGGATTACCCGATCAACAT
CTTCTGA

Upstream 100 bases:

>100_bases
TTGAGCGGGTCTTTTTGTTTCGGGGTGAATAAAAGAGTGCAATAAGCGCCGTTTCAGCCGTTCGACACAGCGCGTTTCAA
CCCGTAATAAGGAAAACAAA

Downstream 100 bases:

>100_bases
TGATCGGTTGAACCCGCGAAACGCGACAGAAAAACCCCGACTCGTTCGGGGTTTTTTTTGACGCTTTTTGAAAAAGCAGC
ATAAAAACCCGTGCTTTTGT

Product: outer membrane porin

Products: NA

Alternate protein names: Imipenem/basic amino acid-specific outer membrane pore; Outer membrane protein D2 [H]

Number of amino acids: Translated: 428; Mature: 428

Protein sequence:

>428_residues
MLNKRISLIALGMLSATSAMANDQAESKGFVEDSSLKVLLRNAYINRDYKDGNQDKAEWGQAAIGTFSSGFTQGTVGVGV
DAFGLYALRLDGGKGRSGAGGIDFFKRGDSGNAADDLSKGGAAVKFRISNTVLTYGDQMPALPVLSYDNVRLLPESYTGT
LITSKEIKGLQLDAGRFTAESRKSAEGRDSGGLKSINVLGGSYQFTEQFKAALYASDVEDVLKKQYVNANYVFPIDKDQS
LTLDFNGYRTKLDNSYVRENGVTGDDNKIWSLAATFATGPHSFTVAHQRSTGDSNLGYAYGGYQKGQGRVGDGGNTIYLA
NSYWSDFNAEDERSWQLGYGLDFSAFGVPGLSYNFAYVRGDNITTSTSEGGTEREIFNQFKYVVQSGPAKDLSIKLRSSI
LRVSQKSSEYNVSGNELRVFVDYPINIF

Sequences:

>Translated_428_residues
MLNKRISLIALGMLSATSAMANDQAESKGFVEDSSLKVLLRNAYINRDYKDGNQDKAEWGQAAIGTFSSGFTQGTVGVGV
DAFGLYALRLDGGKGRSGAGGIDFFKRGDSGNAADDLSKGGAAVKFRISNTVLTYGDQMPALPVLSYDNVRLLPESYTGT
LITSKEIKGLQLDAGRFTAESRKSAEGRDSGGLKSINVLGGSYQFTEQFKAALYASDVEDVLKKQYVNANYVFPIDKDQS
LTLDFNGYRTKLDNSYVRENGVTGDDNKIWSLAATFATGPHSFTVAHQRSTGDSNLGYAYGGYQKGQGRVGDGGNTIYLA
NSYWSDFNAEDERSWQLGYGLDFSAFGVPGLSYNFAYVRGDNITTSTSEGGTEREIFNQFKYVVQSGPAKDLSIKLRSSI
LRVSQKSSEYNVSGNELRVFVDYPINIF
>Mature_428_residues
MLNKRISLIALGMLSATSAMANDQAESKGFVEDSSLKVLLRNAYINRDYKDGNQDKAEWGQAAIGTFSSGFTQGTVGVGV
DAFGLYALRLDGGKGRSGAGGIDFFKRGDSGNAADDLSKGGAAVKFRISNTVLTYGDQMPALPVLSYDNVRLLPESYTGT
LITSKEIKGLQLDAGRFTAESRKSAEGRDSGGLKSINVLGGSYQFTEQFKAALYASDVEDVLKKQYVNANYVFPIDKDQS
LTLDFNGYRTKLDNSYVRENGVTGDDNKIWSLAATFATGPHSFTVAHQRSTGDSNLGYAYGGYQKGQGRVGDGGNTIYLA
NSYWSDFNAEDERSWQLGYGLDFSAFGVPGLSYNFAYVRGDNITTSTSEGGTEREIFNQFKYVVQSGPAKDLSIKLRSSI
LRVSQKSSEYNVSGNELRVFVDYPINIF

Specific function: Porin with a specificity for basic amino acids. Also possesses serine protease activity [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the oprD family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005318 [H]

Pfam domain/function: PF03573 OprD [H]

EC number: NA

Molecular weight: Translated: 46477; Mature: 46477

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNKRISLIALGMLSATSAMANDQAESKGFVEDSSLKVLLRNAYINRDYKDGNQDKAEWG
CCCCEEEEEEEEHHHHHHHHHCCCHHCCCCEECCCCEEEEEHHHCCCCCCCCCCCHHHHC
QAAIGTFSSGFTQGTVGVGVDAFGLYALRLDGGKGRSGAGGIDFFKRGDSGNAADDLSKG
CHHHHCCCCCCCCCCEECCCCCEEEEEEEEECCCCCCCCCCCHHEECCCCCCCHHHHHCC
GAAVKFRISNTVLTYGDQMPALPVLSYDNVRLLPESYTGTLITSKEIKGLQLDAGRFTAE
CCEEEEEEECEEEEECCCCCCCEEEECCCEEECCCCCCCEEEEECCCCCEEEECCCCCCH
SRKSAEGRDSGGLKSINVLGGSYQFTEQFKAALYASDVEDVLKKQYVNANYVFPIDKDQS
HHCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCE
LTLDFNGYRTKLDNSYVRENGVTGDDNKIWSLAATFATGPHSFTVAHQRSTGDSNLGYAY
EEEEECCCEEECCCCHHHHCCCCCCCCCEEEEEEEECCCCCEEEEEEECCCCCCCCCEEE
GGYQKGQGRVGDGGNTIYLANSYWSDFNAEDERSWQLGYGLDFSAFGVPGLSYNFAYVRG
CCEECCCCCCCCCCCEEEEEECCCCCCCCCCCCCEEEECCCCCHHCCCCCCCEEEEEEEC
DNITTSTSEGGTEREIFNQFKYVVQSGPAKDLSIKLRSSILRVSQKSSEYNVSGNELRVF
CCEEECCCCCCCHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHCCCCCCCCCCCEEEEE
VDYPINIF
EECCCEEC
>Mature Secondary Structure
MLNKRISLIALGMLSATSAMANDQAESKGFVEDSSLKVLLRNAYINRDYKDGNQDKAEWG
CCCCEEEEEEEEHHHHHHHHHCCCHHCCCCEECCCCEEEEEHHHCCCCCCCCCCCHHHHC
QAAIGTFSSGFTQGTVGVGVDAFGLYALRLDGGKGRSGAGGIDFFKRGDSGNAADDLSKG
CHHHHCCCCCCCCCCEECCCCCEEEEEEEEECCCCCCCCCCCHHEECCCCCCCHHHHHCC
GAAVKFRISNTVLTYGDQMPALPVLSYDNVRLLPESYTGTLITSKEIKGLQLDAGRFTAE
CCEEEEEEECEEEEECCCCCCCEEEECCCEEECCCCCCCEEEEECCCCCEEEECCCCCCH
SRKSAEGRDSGGLKSINVLGGSYQFTEQFKAALYASDVEDVLKKQYVNANYVFPIDKDQS
HHCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCE
LTLDFNGYRTKLDNSYVRENGVTGDDNKIWSLAATFATGPHSFTVAHQRSTGDSNLGYAY
EEEEECCCEEECCCCHHHHCCCCCCCCCEEEEEEEECCCCCEEEEEEECCCCCCCCCEEE
GGYQKGQGRVGDGGNTIYLANSYWSDFNAEDERSWQLGYGLDFSAFGVPGLSYNFAYVRG
CCEECCCCCCCCCCCEEEEEECCCCCCCCCCCCCEEEECCCCCHHCCCCCCCEEEEEEEC
DNITTSTSEGGTEREIFNQFKYVVQSGPAKDLSIKLRSSILRVSQKSSEYNVSGNELRVF
CCEEECCCCCCCHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHCCCCCCCCCCCEEEEE
VDYPINIF
EECCCEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1339257; 1427017; 10984043; 8012497; 2118530; 8843159; 9636669 [H]