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The map label for this gene is cysQ [H]

Identifier: 77456513

GI number: 77456513

Start: 331172

End: 331999

Strand: Direct

Name: cysQ [H]

Synonym: Pfl01_0285

Alternate gene names: 77456513

Gene position: 331172-331999 (Clockwise)

Preceding gene: 77456512

Following gene: 77456518

Centisome position: 5.14

GC content: 64.37

Gene sequence:

>828_bases
ATGAATTTTCCCCATCCGTTGATGGCGCCGGTGGTCGAGCTGGCATTGCGGGCCGGTGAGGCGATTTTGCCGTTCTGGCG
TGCCGATGTGGCCGTCACCGCCAAGTCCGATGATTCACCGGTGACGGCGGCGGACATGGCCGCTCACCACGTGATCGTGG
CCGGCCTGACAGCGCTGGATCCGAGCATTCCGGTGCTGTCCGAAGAGGACGCCGACATCCCGCAAAGCGTGCGTGCAGGC
TGGCAGCGCTGGTGGCTGGTGGACCCGCTGGATGGCACCAAGGAGTTCATCAGCGGCAGCGAAGAATTCACCGTCAATAT
CGCGTTGATCGAGAATGGCCGGGTGGTGTTCGGTGTGGTGTCGATGCCGACCAACGGTCGCTTCTACGTTGGCGGAGCCG
GGCTCGGTGCCTGGCGCGGCGACACGGGCGGCACGCCGGTGGCGATTCAGGTGCGTGATGTGCCGGGGCCGGGCGAAGCG
TTCACCGTGGTTGCCAGCCGCCGTCATTCGAGTCCGGAGCAGGAACGCTTGCTGGCCGGATTGAGTGCCAGCCTTGGCGA
GTTGCAACTGGCCAACATCGGCAGTTCGCTGAAGTTCTGTCTGCTCGCCGAAGGGGCGGCCGATTGTTACCCGCGACTGG
CGCCGACGTCCCAGTGGGACACAGCGGCGGCGCAGGGCGTTCTGGAAGGCGCCGGCGGCGAGGTTCTGGATTTGAACGGT
GACGCGTTCTGCTATCCACCACGGGATTCGTTACGCAACGCGTTCTTTCTTGCACTGCCGGCAAAAGCGGCGTGGCGTTC
GAAGTTGCTGGAACTGGCCCATTCGTAA

Upstream 100 bases:

>100_bases
AGAATCCGAATTTCAGTGAGGGGCGCGCCCTGGCGGCGCTATACCTGACCCGCGACCTGCTGACCCAGCGCGGATTTTTC
CAGTCATGAGTGAGATGCCA

Downstream 100 bases:

>100_bases
CAGCGCTCCCGGCCCGGAGCGCCAAGCCCTCAGCGGTGCAGGACGTACTGCCCGCTGAAGGTCACTGCATCCTCATTGCT
ACCGGCATTGACGACCCGCG

Product: 3(2),5 -bisphosphate nucleotidase

Products: NA

Alternate protein names: 3'(2'),5-bisphosphonucleoside 3'(2')-phosphohydrolase; 3'-phosphoadenosine 5'-phosphate phosphatase; PAP phosphatase; DPNPase [H]

Number of amino acids: Translated: 275; Mature: 275

Protein sequence:

>275_residues
MNFPHPLMAPVVELALRAGEAILPFWRADVAVTAKSDDSPVTAADMAAHHVIVAGLTALDPSIPVLSEEDADIPQSVRAG
WQRWWLVDPLDGTKEFISGSEEFTVNIALIENGRVVFGVVSMPTNGRFYVGGAGLGAWRGDTGGTPVAIQVRDVPGPGEA
FTVVASRRHSSPEQERLLAGLSASLGELQLANIGSSLKFCLLAEGAADCYPRLAPTSQWDTAAAQGVLEGAGGEVLDLNG
DAFCYPPRDSLRNAFFLALPAKAAWRSKLLELAHS

Sequences:

>Translated_275_residues
MNFPHPLMAPVVELALRAGEAILPFWRADVAVTAKSDDSPVTAADMAAHHVIVAGLTALDPSIPVLSEEDADIPQSVRAG
WQRWWLVDPLDGTKEFISGSEEFTVNIALIENGRVVFGVVSMPTNGRFYVGGAGLGAWRGDTGGTPVAIQVRDVPGPGEA
FTVVASRRHSSPEQERLLAGLSASLGELQLANIGSSLKFCLLAEGAADCYPRLAPTSQWDTAAAQGVLEGAGGEVLDLNG
DAFCYPPRDSLRNAFFLALPAKAAWRSKLLELAHS
>Mature_275_residues
MNFPHPLMAPVVELALRAGEAILPFWRADVAVTAKSDDSPVTAADMAAHHVIVAGLTALDPSIPVLSEEDADIPQSVRAG
WQRWWLVDPLDGTKEFISGSEEFTVNIALIENGRVVFGVVSMPTNGRFYVGGAGLGAWRGDTGGTPVAIQVRDVPGPGEA
FTVVASRRHSSPEQERLLAGLSASLGELQLANIGSSLKFCLLAEGAADCYPRLAPTSQWDTAAAQGVLEGAGGEVLDLNG
DAFCYPPRDSLRNAFFLALPAKAAWRSKLLELAHS

Specific function: Converts 3'(2')-phosphoadenosine 5'-phosphate (PAP) to AMP. May also convert adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) [H]

COG id: COG1218

COG function: function code P; 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inositol monophosphatase family [H]

Homologues:

Organism=Homo sapiens, GI5031789, Length=252, Percent_Identity=27.7777777777778, Blast_Score=78, Evalue=9e-15,
Organism=Homo sapiens, GI221625487, Length=246, Percent_Identity=26.8292682926829, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI7657236, Length=237, Percent_Identity=29.535864978903, Blast_Score=75, Evalue=7e-14,
Organism=Escherichia coli, GI1790659, Length=252, Percent_Identity=48.4126984126984, Blast_Score=191, Evalue=4e-50,
Organism=Escherichia coli, GI1788882, Length=247, Percent_Identity=26.7206477732794, Blast_Score=64, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI71995905, Length=250, Percent_Identity=25.2, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71995897, Length=250, Percent_Identity=25.2, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6324508, Length=281, Percent_Identity=24.9110320284698, Blast_Score=70, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24651149, Length=274, Percent_Identity=29.1970802919708, Blast_Score=84, Evalue=7e-17,
Organism=Drosophila melanogaster, GI24664918, Length=248, Percent_Identity=28.2258064516129, Blast_Score=68, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24641722, Length=275, Percent_Identity=26.1818181818182, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006240
- InterPro:   IPR020583
- InterPro:   IPR000760
- InterPro:   IPR020550 [H]

Pfam domain/function: PF00459 Inositol_P [H]

EC number: =3.1.3.7 [H]

Molecular weight: Translated: 29097; Mature: 29097

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: PS00629 IMP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFPHPLMAPVVELALRAGEAILPFWRADVAVTAKSDDSPVTAADMAAHHVIVAGLTALD
CCCCCHHHHHHHHHHHHCCCEECCEEECCEEEEECCCCCCCCHHHHHHHHHEEEHHHHCC
PSIPVLSEEDADIPQSVRAGWQRWWLVDPLDGTKEFISGSEEFTVNIALIENGRVVFGVV
CCCCCCCCCCCCCCHHHHCCHHEEEEECCCCCHHHHHCCCCEEEEEEEEEECCEEEEEEE
SMPTNGRFYVGGAGLGAWRGDTGGTPVAIQVRDVPGPGEAFTVVASRRHSSPEQERLLAG
ECCCCCEEEECCCCCCCCCCCCCCCEEEEEEEECCCCCCEEEEEECCCCCCCHHHHHHHH
LSASLGELQLANIGSSLKFCLLAEGAADCYPRLAPTSQWDTAAAQGVLEGAGGEVLDLNG
HCCCCCCEEEECCCCCEEEEEEECCCHHCCCCCCCCCCCCHHHHHHHHCCCCCCEEECCC
DAFCYPPRDSLRNAFFLALPAKAAWRSKLLELAHS
CEEEECCHHHHCCEEEEEECCHHHHHHHHHHHHCC
>Mature Secondary Structure
MNFPHPLMAPVVELALRAGEAILPFWRADVAVTAKSDDSPVTAADMAAHHVIVAGLTALD
CCCCCHHHHHHHHHHHHCCCEECCEEECCEEEEECCCCCCCCHHHHHHHHHEEEHHHHCC
PSIPVLSEEDADIPQSVRAGWQRWWLVDPLDGTKEFISGSEEFTVNIALIENGRVVFGVV
CCCCCCCCCCCCCCHHHHCCHHEEEEECCCCCHHHHHCCCCEEEEEEEEEECCEEEEEEE
SMPTNGRFYVGGAGLGAWRGDTGGTPVAIQVRDVPGPGEAFTVVASRRHSSPEQERLLAG
ECCCCCEEEECCCCCCCCCCCCCCCEEEEEEEECCCCCCEEEEEECCCCCCCHHHHHHHH
LSASLGELQLANIGSSLKFCLLAEGAADCYPRLAPTSQWDTAAAQGVLEGAGGEVLDLNG
HCCCCCCEEEECCCCCEEEEEEECCCHHCCCCCCCCCCCCHHHHHHHHCCCCCCEEECCC
DAFCYPPRDSLRNAFFLALPAKAAWRSKLLELAHS
CEEEECCHHHHCCEEEEEECCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]