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The map label for this gene is zur [H]

Identifier: 77456288

GI number: 77456288

Start: 66269

End: 66751

Strand: Direct

Name: zur [H]

Synonym: Pfl01_0060

Alternate gene names: 77456288

Gene position: 66269-66751 (Clockwise)

Preceding gene: 77456286

Following gene: 77456289

Centisome position: 1.03

GC content: 63.98

Gene sequence:

>483_bases
ATGCCTATTACACCGATTGCCAGCCGTCCCCACGACCACTCGCACTGCGTTCATAGCGCGCTGTCCGAGGCCGATGCTCT
GTGTGCACAGAAAGGCCTGCGCCTGACCGCGCTGCGCCGGCGGGTGCTGGAGCTGGTCTGGCAGAGCCACAAGCCGCTGG
GTGCCTACGACATTCTGGCGGTGCTCAGCGAGCAGGACGGCCGCCGCGCCGCGCCGCCAACCGTGTACCGCGCGCTGGAT
TTCCTGCTGGAAAACGGTCTGGTGCACCGCATCTCCTCGCTCAACGCCTTCGTCGGCTGTGTTCACCCGAAACATTCGCA
CCAAGGCCAGTTCCTGATCTGCCGTGAATGCCACGCCGCCATCGAGCTTGAGCAAAAAACCATCAGCGACGCCATCGTCC
ACAGCGCTAAGGATGTCGGCTTCATCGTTGAGGCCCAGACCGTCGAAGTGGTCGGTCTCTGCTCCGGTTGCCGGGGGGCT
TGA

Upstream 100 bases:

>100_bases
TGAATACGACAAAAACAGAAAAAAGTCGGGACACGATGACCACTCAATGAGGCGAGAACGGGTAACATAATAACGTCTCT
AACCAAACTCGTCGCCGCTC

Downstream 100 bases:

>100_bases
TGAGCGATGCGCTGATCCGTCTGGAGAAGGTGGCGGTCCGGTTTGCCGGGCAGAACGTGCTGGACAACATTCACCTGAGC
GTTGAACCGGGGCAGATCGT

Product: zinc uptake regulation protein

Products: NA

Alternate protein names: Zinc uptake regulator [H]

Number of amino acids: Translated: 160; Mature: 159

Protein sequence:

>160_residues
MPITPIASRPHDHSHCVHSALSEADALCAQKGLRLTALRRRVLELVWQSHKPLGAYDILAVLSEQDGRRAAPPTVYRALD
FLLENGLVHRISSLNAFVGCVHPKHSHQGQFLICRECHAAIELEQKTISDAIVHSAKDVGFIVEAQTVEVVGLCSGCRGA

Sequences:

>Translated_160_residues
MPITPIASRPHDHSHCVHSALSEADALCAQKGLRLTALRRRVLELVWQSHKPLGAYDILAVLSEQDGRRAAPPTVYRALD
FLLENGLVHRISSLNAFVGCVHPKHSHQGQFLICRECHAAIELEQKTISDAIVHSAKDVGFIVEAQTVEVVGLCSGCRGA
>Mature_159_residues
PITPIASRPHDHSHCVHSALSEADALCAQKGLRLTALRRRVLELVWQSHKPLGAYDILAVLSEQDGRRAAPPTVYRALDF
LLENGLVHRISSLNAFVGCVHPKHSHQGQFLICRECHAAIELEQKTISDAIVHSAKDVGFIVEAQTVEVVGLCSGCRGA

Specific function: Acts as a negative controlling element, employing Zn(2+) as a cofactor to bind the operator of the repressed genes (znuACB) [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI87082363, Length=138, Percent_Identity=39.1304347826087, Blast_Score=99, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 17456; Mature: 17325

Theoretical pI: Translated: 7.58; Mature: 7.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.4 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
4.4 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPITPIASRPHDHSHCVHSALSEADALCAQKGLRLTALRRRVLELVWQSHKPLGAYDILA
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCHHHHHH
VLSEQDGRRAAPPTVYRALDFLLENGLVHRISSLNAFVGCVHPKHSHQGQFLICRECHAA
HHHCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCEEEHHHHHHH
IELEQKTISDAIVHSAKDVGFIVEAQTVEVVGLCSGCRGA
HHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
PITPIASRPHDHSHCVHSALSEADALCAQKGLRLTALRRRVLELVWQSHKPLGAYDILA
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCHHHHHH
VLSEQDGRRAAPPTVYRALDFLLENGLVHRISSLNAFVGCVHPKHSHQGQFLICRECHAA
HHHCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCEEEHHHHHHH
IELEQKTISDAIVHSAKDVGFIVEAQTVEVVGLCSGCRGA
HHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503; 9680209 [H]