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The map label for this gene is thrB [H]

Identifier: 77456286

GI number: 77456286

Start: 64287

End: 65240

Strand: Direct

Name: thrB [H]

Synonym: Pfl01_0058

Alternate gene names: 77456286

Gene position: 64287-65240 (Clockwise)

Preceding gene: 77456285

Following gene: 77456288

Centisome position: 1.0

GC content: 62.79

Gene sequence:

>954_bases
ATGTCTGTGTTCACCCCCCTGGCTCGGCCCGAGCTGGAAACCTTTCTCGCCCCTTACGGGCTCGGCCGTCTGCTCGATTT
CCAGGGGATCGCCGCCGGCAGCGAAAACACCAACTTCTTCATCAGCATGGAAAAGGGCGAGTTCGTCCTGACCCTGGTCG
AGCGCGGCCCGGTGCAGGAAATGCCTTTCTTCATCGACCTGCTAGACGTCCTGCACGAAGCCGATCTGCCGGTGCCTTAC
GCACTGCGCACCACCGACGGCGTGGCCCTGCGCGAGCTGAAGGGCAAACCGGCATTGCTGCAACCGCGCCTGGCTGGCAA
GCACATCAAGCAGGCCAACGCCCAGCATTGCGCGCAGGTCGGTGACTTGCAGGCGCATCTGCACCTGGCGACCCAGGGCG
ACAACATGATCAAGCGCAAGACCGATCGTGGCCTGGACTGGATGCTGGAAGAGGGTACGCAGTTTCTTTCGCACCTGAGC
GATGAGCCGCGCGCACTGCTGCAGAAGGCGCTGGACGAAATCACCCAACAGAGAGAGAAAATTCTCGCGCTGCCACGGGC
GAACATCCACGCCGACCTGTTCCGCGACAACGCGATGTTCGAAGGCACACACCTGACCGGGTTGATCGACTTCTACAACG
CCTGCTCCGGGCCGATGCTCTATGACGTGGCGATTGCTCTGAACGACTGGTGTTCGGACGATAACGGCCTGATCGACGGC
CCGCGTGCTCGGGCCTTCCTCGGTGCCTATGCGGCACTGCGTCCATTCACGGCGGCCGAAGCCGAGCTGTGGCCGACCAT
GCTGCGAGTGGCGTGCGTTCGGTTCTGGCTGTCGCGCCTGATTGCGGCGGAATCGTTCGCCGGGCAGGACGTGCTGATTC
ACGATCCGAAAGAGTTCGAGCAGCGCCTGGCGCAGCGTCAGACGGTCAGTACGCCGCTACCTTTCGCCCTGTAA

Upstream 100 bases:

>100_bases
ATGCTGATTCCGTCGTGGGAAATCTTTACCTGGAAGTAAGTTTCCTGACTTTTAATCGGCGCCGTCTGATGGCGGCGCCA
GAACTGAGCAGTTTTTAACC

Downstream 100 bases:

>100_bases
AAGAAAAAACCGCAGCCTGTGCAGGCTGCGGTTTTTTTGTATCAGAGCGATTCGAGACAACCCGCCAGATCATTCCCCAG
CTTCTCCAGCACTTGCTCGT

Product: homoserine kinase

Products: NA

Alternate protein names: HK; HSK [H]

Number of amino acids: Translated: 317; Mature: 316

Protein sequence:

>317_residues
MSVFTPLARPELETFLAPYGLGRLLDFQGIAAGSENTNFFISMEKGEFVLTLVERGPVQEMPFFIDLLDVLHEADLPVPY
ALRTTDGVALRELKGKPALLQPRLAGKHIKQANAQHCAQVGDLQAHLHLATQGDNMIKRKTDRGLDWMLEEGTQFLSHLS
DEPRALLQKALDEITQQREKILALPRANIHADLFRDNAMFEGTHLTGLIDFYNACSGPMLYDVAIALNDWCSDDNGLIDG
PRARAFLGAYAALRPFTAAEAELWPTMLRVACVRFWLSRLIAAESFAGQDVLIHDPKEFEQRLAQRQTVSTPLPFAL

Sequences:

>Translated_317_residues
MSVFTPLARPELETFLAPYGLGRLLDFQGIAAGSENTNFFISMEKGEFVLTLVERGPVQEMPFFIDLLDVLHEADLPVPY
ALRTTDGVALRELKGKPALLQPRLAGKHIKQANAQHCAQVGDLQAHLHLATQGDNMIKRKTDRGLDWMLEEGTQFLSHLS
DEPRALLQKALDEITQQREKILALPRANIHADLFRDNAMFEGTHLTGLIDFYNACSGPMLYDVAIALNDWCSDDNGLIDG
PRARAFLGAYAALRPFTAAEAELWPTMLRVACVRFWLSRLIAAESFAGQDVLIHDPKEFEQRLAQRQTVSTPLPFAL
>Mature_316_residues
SVFTPLARPELETFLAPYGLGRLLDFQGIAAGSENTNFFISMEKGEFVLTLVERGPVQEMPFFIDLLDVLHEADLPVPYA
LRTTDGVALRELKGKPALLQPRLAGKHIKQANAQHCAQVGDLQAHLHLATQGDNMIKRKTDRGLDWMLEEGTQFLSHLSD
EPRALLQKALDEITQQREKILALPRANIHADLFRDNAMFEGTHLTGLIDFYNACSGPMLYDVAIALNDWCSDDNGLIDGP
RARAFLGAYAALRPFTAAEAELWPTMLRVACVRFWLSRLIAAESFAGQDVLIHDPKEFEQRLAQRQTVSTPLPFAL

Specific function: Unknown

COG id: COG2334

COG function: function code R; Putative homoserine kinase type II (protein kinase fold)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pseudomonas-type thrB family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002575
- InterPro:   IPR005280
- InterPro:   IPR011009 [H]

Pfam domain/function: PF01636 APH [H]

EC number: =2.7.1.39 [H]

Molecular weight: Translated: 35379; Mature: 35248

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVFTPLARPELETFLAPYGLGRLLDFQGIAAGSENTNFFISMEKGEFVLTLVERGPVQE
CCCCCCCCCHHHHHHHHCCCHHHHHCCCCCCCCCCCCEEEEEEECCCEEEEEECCCCHHH
MPFFIDLLDVLHEADLPVPYALRTTDGVALRELKGKPALLQPRLAGKHIKQANAQHCAQV
CHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHCCCCCEECCHHHHHHHHHCCHHHHHHH
GDLQAHLHLATQGDNMIKRKTDRGLDWMLEEGTQFLSHLSDEPRALLQKALDEITQQREK
CCCEEEEEEEECCCHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
ILALPRANIHADLFRDNAMFEGTHLTGLIDFYNACSGPMLYDVAIALNDWCSDDNGLIDG
HHHCCCCCCHHHHHHCCCEECCCHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCC
PRARAFLGAYAALRPFTAAEAELWPTMLRVACVRFWLSRLIAAESFAGQDVLIHDPKEFE
CHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECHHHHH
QRLAQRQTVSTPLPFAL
HHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
SVFTPLARPELETFLAPYGLGRLLDFQGIAAGSENTNFFISMEKGEFVLTLVERGPVQE
CCCCCCCCHHHHHHHHCCCHHHHHCCCCCCCCCCCCEEEEEEECCCEEEEEECCCCHHH
MPFFIDLLDVLHEADLPVPYALRTTDGVALRELKGKPALLQPRLAGKHIKQANAQHCAQV
CHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHCCCCCEECCHHHHHHHHHCCHHHHHHH
GDLQAHLHLATQGDNMIKRKTDRGLDWMLEEGTQFLSHLSDEPRALLQKALDEITQQREK
CCCEEEEEEEECCCHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
ILALPRANIHADLFRDNAMFEGTHLTGLIDFYNACSGPMLYDVAIALNDWCSDDNGLIDG
HHHCCCCCCHHHHHHCCCEECCCHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCC
PRARAFLGAYAALRPFTAAEAELWPTMLRVACVRFWLSRLIAAESFAGQDVLIHDPKEFE
CHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECHHHHH
QRLAQRQTVSTPLPFAL
HHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA