| Definition | Burkholderia pseudomallei 1710b chromosome chromosome II, complete sequence. |
|---|---|
| Accession | NC_007435 |
| Length | 3,181,762 |
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The map label for this gene is hscA [H]
Identifier: 76818939
GI number: 76818939
Start: 73649
End: 76456
Strand: Direct
Name: hscA [H]
Synonym: BURPS1710b_A0047
Alternate gene names: 76818939
Gene position: 73649-76456 (Clockwise)
Preceding gene: 76819769
Following gene: 76818015
Centisome position: 2.31
GC content: 73.97
Gene sequence:
>2808_bases ATGAAACGATTCATCGTCGGCATCGATCTCGGGACGAGCAATACCGTCGTGGCGTACGTCGAGGCGGGCGGCGACGCGAT CCGCGTGTTCGACGTCGAGCAACTCGTCGCGCCCGGCGAAGTCGGCGCGCGGCCGCTGCTGCCTTCGGCGCGCTATCACC CGGCGCCCGGCGAGTTCGCGCCGGGCGACCTGCGGCTGCCGTGGCGCGATGCCGGCGAATCGGTCGACGCGCACGCTGCG TCCGACGCCGGCGACGCGCCGCCCGCGGTGATCGGCACGCTCGCGCGCGCGCTCGGCGCGCAGGTGCCGGGCCGGCTCGT GACGAGCGCGAAAAGCTGGCTGTCGCACGCGTCGGTCGATCGTCTCGCGCCGATCCTGCCGTGGGGCGCGGCCGATGCGC ACGGCAAGGTGTCGCCCGTCGCGGCGTGCGCGAGCTATCTCGCGCACGTGCGCGCCGCATGGAACCGCCGCTTTCCGGAT GCGCCGCTCGAACGGCAGGACATCGTGCTCACCGTGCCCGCGTCGTTCGACGACGGCGCGCGCGCACTCACGCTCGAAGC CGCGCGACTCGCGAAGCTGCCCGCGCTGCGCTTGCTGGAGGAGCCCCAGGCCGCGTTCTACGACTGGCTGTTCCATCATC GCGACACGCTGCGCGACGAGCTGGCGCGCACGCGCCTCGTGCTCGTGTGCGACGTCGGCGGCGGCACGACCGACCTCACG CTGATCAAGGTGCACGTCGAGAACGGCGAGCCGCGGTTGACGCGCATCGGCGTGGGCGATCACCTGATGCTCGGCGGCGA CAACATGGATCTCGCGCTCGCGCGCGTCGCCGAGATGCGGCTCGCGCAGGACGGCGGCGCGCGCCTGTCGGCGGCGGCGC TGTCGCAACTCGTCGAACGCTGCCGCGCGGCGAAGGAGCAACTGCTCGGCGAGCATCCGCCCGATGCGCTCGCGCTCACG CTGCTCGGCGCCGGCGCACGGCTCGTCGGCGGCGCGCGCAAGACCGCGCTGAGCCGCGCGGAGGTCGAGCAGATCGTCGT CGACGGTTTTTTTCCGGCGGGCGGCCCGGACGATCTGCCGCGCCGCTCGCGCGCGGCGCTCGTCGAATTCGGCCTGCCCT ACGCCGCCGACGCGGCCGTCACGCGGCATGTCGCGGCGTTCCTGCATCGGCTCGCCGCGCAGTCGCGCGACGCGCTCGGC GCGGCGGCCGCGGATCGGGCGTTGCCGGTGCCCGACACACTGCTGCTCAACGGCGGCGTGTTCCGCTCGAACGCGCTCGC CGGGCGCCTCGCGGGCGTGCTCGGCGACTGGCGCGGGCAGCCGCTGCACGTGCTGCACAACGCCCATCCGGACGTCGCGG TCGCGCGCGGCGCGGTCGCGTACGGGCTCGCGCGCGCCGGGCGCGCGCCGAGGATCGGCGGCGGCTCGCCGCGCAGCTAT TTCCTGGTCGTCGACGACGGCGCGCACGCGTCGCGCGGCGTCTGCGTGCTGCCGCGCGGCACGGCGGAAGGGCACGACGT GCATCTCGACGATCGCGTGTTCGCGCTGCGGCTCGGCCACCCGGTGCGCTTCCATCTGGCATCGACCGTCGCCGACCACG CATGGCGGGCGGGCGAGCTCGCGGATCTCGGCGCGGGCGATTTCGTCCGGCTGCCGCCCGTCGCGACGGTCGTTCGGCAG CAGGACGCGGGCGGCGCGCGCGAGCGGCTCGTCAGGCTGACGACGGCGCTCACCGAGGTCGGCACGCTCGACATGCGCTG CATCGCGACGGATGATCCGTCGCAACGCTGGCAACTCGAATTCCAGCTCAGACGCGAGCAGGCGCGACACGCCGACGCGG CGCCCGACGCGTCGCGCCATCCGTCGCTCGACCACGCGCTCGAGCTGATCGACCGCGCGTTCGGCGCGCGGCTCGCGAAC GTCGATCCGAAGGAAGTCCGGCGTCTGCGCACGCAGCTCGAGCAGGCGCTCGGCCCGCGCGATGCGTGGGACATCGCCCT CCTGCGCGAGCTGTTCGGCGCGCTGTGGGAGCGCGCCGGCCGGCGGCGGCGCTCGGCGGATCACGAGCGCGTCTGGCTGA ACCTGGCCGGCTATTGCGTGCGGCCCGGCTTCGGCCATCCGCTCGACGACTGGCGCGTCGCGCAGCTCTGGACATTGTTC GACGACGGCATCCAGTACGTGAACGACGCCCGGGTGTGGTCCGAGTGGTGGACGCTGTGGCGCCGGGCGGCGGGCGGGCT CGACGACGACGCGCAGCAGCAGGCGCTCGACGCGATGGCGTGGCTGCGGCAGGCCGCGGGCGCGAAGCGGCCGAAGCTGC CGTTCGACGCCGCGAAGATCGGCGACATGGACATGGTGCGCCTGTCCGCGTCGCTCGAGCGCGTGCCCGTCGAGCGCAAG ATCGAGCTCGGCGAGCAGTTGCTCGCGCGGCTGCAAAAACCGGCCGAGAATCACCAGTGCTGGTGGGCGATCGGGCGCAT CGGCGCGCGGTGGCCGCTGTACGGCAGCGCGCACGGCATCGTGCCGCCCGAGGTCGCGCAGCGCTGGCTGGACGCGCTCC TCGCCGTCGACTGGAAGAAGGTCGAGCCGGCCGCTTTCGCGGCCGCGCAGATCGCGCGGATGACGGGCGATCGCACGGGC GACGTGCCGGCCGACGTGCGCGAGCGGGTCCTGCGCCGGCTCGCGGCGACGAACGGCTCGGATGCGTGGGTCCGCATGGT GAGCGAGGTCGTCGCGCTGGATAACGCGGATACCGGCCGCGCGTTCGGCGAATCGCTGCCCGCCGGGTTGAAGCTCGTCG CCGGCTGA
Upstream 100 bases:
>100_bases GACGGAGGCCGGCACGCTCGAGCTCGAAGCCGTGCAAGGCGGCACGCACGAGCGCTGGAAGGTGGAGTTCGACGTGCGCG GCGGCGCGAACGCGTAACCG
Downstream 100 bases:
>100_bases GCGCGAGCGCGCGGGCGCGGGCCGTTCGGCGCCATCGCGGCGCACGGGCGTGCGGCGGGGCTTCGGCACAGGCGGCTCAC GACGGTTCGGGGGAGCTTGC
Product: heat shock protein 70
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 935; Mature: 935
Protein sequence:
>935_residues MKRFIVGIDLGTSNTVVAYVEAGGDAIRVFDVEQLVAPGEVGARPLLPSARYHPAPGEFAPGDLRLPWRDAGESVDAHAA SDAGDAPPAVIGTLARALGAQVPGRLVTSAKSWLSHASVDRLAPILPWGAADAHGKVSPVAACASYLAHVRAAWNRRFPD APLERQDIVLTVPASFDDGARALTLEAARLAKLPALRLLEEPQAAFYDWLFHHRDTLRDELARTRLVLVCDVGGGTTDLT LIKVHVENGEPRLTRIGVGDHLMLGGDNMDLALARVAEMRLAQDGGARLSAAALSQLVERCRAAKEQLLGEHPPDALALT LLGAGARLVGGARKTALSRAEVEQIVVDGFFPAGGPDDLPRRSRAALVEFGLPYAADAAVTRHVAAFLHRLAAQSRDALG AAAADRALPVPDTLLLNGGVFRSNALAGRLAGVLGDWRGQPLHVLHNAHPDVAVARGAVAYGLARAGRAPRIGGGSPRSY FLVVDDGAHASRGVCVLPRGTAEGHDVHLDDRVFALRLGHPVRFHLASTVADHAWRAGELADLGAGDFVRLPPVATVVRQ QDAGGARERLVRLTTALTEVGTLDMRCIATDDPSQRWQLEFQLRREQARHADAAPDASRHPSLDHALELIDRAFGARLAN VDPKEVRRLRTQLEQALGPRDAWDIALLRELFGALWERAGRRRRSADHERVWLNLAGYCVRPGFGHPLDDWRVAQLWTLF DDGIQYVNDARVWSEWWTLWRRAAGGLDDDAQQQALDAMAWLRQAAGAKRPKLPFDAAKIGDMDMVRLSASLERVPVERK IELGEQLLARLQKPAENHQCWWAIGRIGARWPLYGSAHGIVPPEVAQRWLDALLAVDWKKVEPAAFAAAQIARMTGDRTG DVPADVRERVLRRLAATNGSDAWVRMVSEVVALDNADTGRAFGESLPAGLKLVAG
Sequences:
>Translated_935_residues MKRFIVGIDLGTSNTVVAYVEAGGDAIRVFDVEQLVAPGEVGARPLLPSARYHPAPGEFAPGDLRLPWRDAGESVDAHAA SDAGDAPPAVIGTLARALGAQVPGRLVTSAKSWLSHASVDRLAPILPWGAADAHGKVSPVAACASYLAHVRAAWNRRFPD APLERQDIVLTVPASFDDGARALTLEAARLAKLPALRLLEEPQAAFYDWLFHHRDTLRDELARTRLVLVCDVGGGTTDLT LIKVHVENGEPRLTRIGVGDHLMLGGDNMDLALARVAEMRLAQDGGARLSAAALSQLVERCRAAKEQLLGEHPPDALALT LLGAGARLVGGARKTALSRAEVEQIVVDGFFPAGGPDDLPRRSRAALVEFGLPYAADAAVTRHVAAFLHRLAAQSRDALG AAAADRALPVPDTLLLNGGVFRSNALAGRLAGVLGDWRGQPLHVLHNAHPDVAVARGAVAYGLARAGRAPRIGGGSPRSY FLVVDDGAHASRGVCVLPRGTAEGHDVHLDDRVFALRLGHPVRFHLASTVADHAWRAGELADLGAGDFVRLPPVATVVRQ QDAGGARERLVRLTTALTEVGTLDMRCIATDDPSQRWQLEFQLRREQARHADAAPDASRHPSLDHALELIDRAFGARLAN VDPKEVRRLRTQLEQALGPRDAWDIALLRELFGALWERAGRRRRSADHERVWLNLAGYCVRPGFGHPLDDWRVAQLWTLF DDGIQYVNDARVWSEWWTLWRRAAGGLDDDAQQQALDAMAWLRQAAGAKRPKLPFDAAKIGDMDMVRLSASLERVPVERK IELGEQLLARLQKPAENHQCWWAIGRIGARWPLYGSAHGIVPPEVAQRWLDALLAVDWKKVEPAAFAAAQIARMTGDRTG DVPADVRERVLRRLAATNGSDAWVRMVSEVVALDNADTGRAFGESLPAGLKLVAG >Mature_935_residues MKRFIVGIDLGTSNTVVAYVEAGGDAIRVFDVEQLVAPGEVGARPLLPSARYHPAPGEFAPGDLRLPWRDAGESVDAHAA SDAGDAPPAVIGTLARALGAQVPGRLVTSAKSWLSHASVDRLAPILPWGAADAHGKVSPVAACASYLAHVRAAWNRRFPD APLERQDIVLTVPASFDDGARALTLEAARLAKLPALRLLEEPQAAFYDWLFHHRDTLRDELARTRLVLVCDVGGGTTDLT LIKVHVENGEPRLTRIGVGDHLMLGGDNMDLALARVAEMRLAQDGGARLSAAALSQLVERCRAAKEQLLGEHPPDALALT LLGAGARLVGGARKTALSRAEVEQIVVDGFFPAGGPDDLPRRSRAALVEFGLPYAADAAVTRHVAAFLHRLAAQSRDALG AAAADRALPVPDTLLLNGGVFRSNALAGRLAGVLGDWRGQPLHVLHNAHPDVAVARGAVAYGLARAGRAPRIGGGSPRSY FLVVDDGAHASRGVCVLPRGTAEGHDVHLDDRVFALRLGHPVRFHLASTVADHAWRAGELADLGAGDFVRLPPVATVVRQ QDAGGARERLVRLTTALTEVGTLDMRCIATDDPSQRWQLEFQLRREQARHADAAPDASRHPSLDHALELIDRAFGARLAN VDPKEVRRLRTQLEQALGPRDAWDIALLRELFGALWERAGRRRRSADHERVWLNLAGYCVRPGFGHPLDDWRVAQLWTLF DDGIQYVNDARVWSEWWTLWRRAAGGLDDDAQQQALDAMAWLRQAAGAKRPKLPFDAAKIGDMDMVRLSASLERVPVERK IELGEQLLARLQKPAENHQCWWAIGRIGARWPLYGSAHGIVPPEVAQRWLDALLAVDWKKVEPAAFAAAQIARMTGDRTG DVPADVRERVLRRLAATNGSDAWVRMVSEVVALDNADTGRAFGESLPAGLKLVAG
Specific function: Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by hscB [H]
COG id: COG0443
COG function: function code O; Molecular chaperone
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the heat shock protein 70 family [H]
Homologues:
Organism=Escherichia coli, GI1788875, Length=285, Percent_Identity=28.4210526315789, Blast_Score=70, Evalue=9e-13, Organism=Escherichia coli, GI1786196, Length=363, Percent_Identity=25.068870523416, Blast_Score=65, Evalue=2e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR018181 - InterPro: IPR001023 - InterPro: IPR013126 - InterPro: IPR010236 [H]
Pfam domain/function: PF00012 HSP70 [H]
EC number: NA
Molecular weight: Translated: 101100; Mature: 101100
Theoretical pI: Translated: 7.48; Mature: 7.48
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.7 %Cys (Translated Protein) 1.1 %Met (Translated Protein) 1.8 %Cys+Met (Translated Protein) 0.7 %Cys (Mature Protein) 1.1 %Met (Mature Protein) 1.8 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKRFIVGIDLGTSNTVVAYVEAGGDAIRVFDVEQLVAPGEVGARPLLPSARYHPAPGEFA CCEEEEEEEECCCCCEEEEEECCCCEEEEEEHHHHHCCCCCCCCCCCCCCCCCCCCCCCC PGDLRLPWRDAGESVDAHAASDAGDAPPAVIGTLARALGAQVPGRLVTSAKSWLSHASVD CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH RLAPILPWGAADAHGKVSPVAACASYLAHVRAAWNRRFPDAPLERQDIVLTVPASFDDGA HHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCC RALTLEAARLAKLPALRLLEEPQAAFYDWLFHHRDTLRDELARTRLVLVCDVGGGTTDLT CEEEHHHHHHHHCHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCCCCEEE LIKVHVENGEPRLTRIGVGDHLMLGGDNMDLALARVAEMRLAQDGGARLSAAALSQLVER EEEEEEECCCCEEEEECCCCEEEECCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH CRAAKEQLLGEHPPDALALTLLGAGARLVGGARKTALSRAEVEQIVVDGFFPAGGPDDLP HHHHHHHHCCCCCCHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCC RRSRAALVEFGLPYAADAAVTRHVAAFLHRLAAQSRDALGAAAADRALPVPDTLLLNGGV CHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCEEEECCCC FRSNALAGRLAGVLGDWRGQPLHVLHNAHPDVAVARGAVAYGLARAGRAPRIGGGSPRSY EECCHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEE FLVVDDGAHASRGVCVLPRGTAEGHDVHLDDRVFALRLGHPVRFHLASTVADHAWRAGEL EEEEECCCCCCCCEEEEECCCCCCCEEEECCCEEEEECCCCEEEHHHHHHHHHHHCCCCC ADLGAGDFVRLPPVATVVRQQDAGGARERLVRLTTALTEVGTLDMRCIATDDPSQRWQLE CCCCCCCEEECCCHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCEEHH FQLRREQARHADAAPDASRHPSLDHALELIDRAFGARLANVDPKEVRRLRTQLEQALGPR HHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCC DAWDIALLRELFGALWERAGRRRRSADHERVWLNLAGYCVRPGFGHPLDDWRVAQLWTLF CHHHHHHHHHHHHHHHHHHHHHHCCCCHHEEEEEECCEEECCCCCCCCCCCHHHHHHHHH DDGIQYVNDARVWSEWWTLWRRAAGGLDDDAQQQALDAMAWLRQAAGAKRPKLPFDAAKI HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHC GDMDMVRLSASLERVPVERKIELGEQLLARLQKPAENHQCWWAIGRIGARWPLYGSAHGI CCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCCC VPPEVAQRWLDALLAVDWKKVEPAAFAAAQIARMTGDRTGDVPADVRERVLRRLAATNGS CCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCC DAWVRMVSEVVALDNADTGRAFGESLPAGLKLVAG HHHHHHHHHHHHHCCCCCCHHHHHCCCCCEEEECC >Mature Secondary Structure MKRFIVGIDLGTSNTVVAYVEAGGDAIRVFDVEQLVAPGEVGARPLLPSARYHPAPGEFA CCEEEEEEEECCCCCEEEEEECCCCEEEEEEHHHHHCCCCCCCCCCCCCCCCCCCCCCCC PGDLRLPWRDAGESVDAHAASDAGDAPPAVIGTLARALGAQVPGRLVTSAKSWLSHASVD CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH RLAPILPWGAADAHGKVSPVAACASYLAHVRAAWNRRFPDAPLERQDIVLTVPASFDDGA HHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCC RALTLEAARLAKLPALRLLEEPQAAFYDWLFHHRDTLRDELARTRLVLVCDVGGGTTDLT CEEEHHHHHHHHCHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCCCCEEE LIKVHVENGEPRLTRIGVGDHLMLGGDNMDLALARVAEMRLAQDGGARLSAAALSQLVER EEEEEEECCCCEEEEECCCCEEEECCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH CRAAKEQLLGEHPPDALALTLLGAGARLVGGARKTALSRAEVEQIVVDGFFPAGGPDDLP HHHHHHHHCCCCCCHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCC RRSRAALVEFGLPYAADAAVTRHVAAFLHRLAAQSRDALGAAAADRALPVPDTLLLNGGV CHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCEEEECCCC FRSNALAGRLAGVLGDWRGQPLHVLHNAHPDVAVARGAVAYGLARAGRAPRIGGGSPRSY EECCHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEE FLVVDDGAHASRGVCVLPRGTAEGHDVHLDDRVFALRLGHPVRFHLASTVADHAWRAGEL EEEEECCCCCCCCEEEEECCCCCCCEEEECCCEEEEECCCCEEEHHHHHHHHHHHCCCCC ADLGAGDFVRLPPVATVVRQQDAGGARERLVRLTTALTEVGTLDMRCIATDDPSQRWQLE CCCCCCCEEECCCHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCEEHH FQLRREQARHADAAPDASRHPSLDHALELIDRAFGARLANVDPKEVRRLRTQLEQALGPR HHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCC DAWDIALLRELFGALWERAGRRRRSADHERVWLNLAGYCVRPGFGHPLDDWRVAQLWTLF CHHHHHHHHHHHHHHHHHHHHHHCCCCHHEEEEEECCEEECCCCCCCCCCCHHHHHHHHH DDGIQYVNDARVWSEWWTLWRRAAGGLDDDAQQQALDAMAWLRQAAGAKRPKLPFDAAKI HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHC GDMDMVRLSASLERVPVERKIELGEQLLARLQKPAENHQCWWAIGRIGARWPLYGSAHGI CCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCCC VPPEVAQRWLDALLAVDWKKVEPAAFAAAQIARMTGDRTGDVPADVRERVLRRLAATNGS CCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCC DAWVRMVSEVVALDNADTGRAFGESLPAGLKLVAG HHHHHHHHHHHHHCCCCCCHHHHHCCCCCEEEECC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: NA