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The map label for this gene is trpS [H]

Identifier: 76818779

GI number: 76818779

Start: 1217256

End: 1218296

Strand: Direct

Name: trpS [H]

Synonym: BURPS1710b_A0956

Alternate gene names: 76818779

Gene position: 1217256-1218296 (Clockwise)

Preceding gene: 76819703

Following gene: 76818449

Centisome position: 38.26

GC content: 68.4

Gene sequence:

>1041_bases
ATGCACGACGACACCTCGAATCCTTCCCGAGCGCCGATCGCACTGACCGGCGACCGCCCGACGGGCGCGCTGCACCTCGG
CCATTACATCGGCTCGCTGAAGACGCGCATCGCGCTTCAGGACACGCACCGGCAATTCATCCTCGTCGCCGACACGCAGG
CGCTGACCGACAACGCGCACGATCCCGACAAGGTTCGCCGCAACGTGATCGAAGTCGCGCTCGACTATCTGGCCGTCGGC
ATCGATCCGCGCCGGAGCACGATCGCCGTGCAGTCGGGCCTGCCCGCGCTCGCCGAGCTGACGCTCTTCTATCTGAACTT
CGTCACCGTCGCGCGCCTCGAGCGCAATCCGACGATCAAGGACGAGATCCACGCGCGCGGCTTCGGCCGCGACATTCCCG
CCGGCTTTCTCTGCTACCCGGTCGCGCAGGCGGCCGACATCACTGCGTTCAAGGCCGACACGGTGCCCGTCGGCGACGAT
CAACTGCCGCTCATCGAGCAGACGAACGAGATCGTCCGTCGCGTCAACCGGCAGGCGGGCGCCGACGTGCTGCCCGAGGC
GAGCGCGCTGATCTCGCCGACGGGACGGCTGCCGGGCGTCGACGGCAAGGCGAAGATGAGCAAATCGCAAGGCAACGCGA
TCGCGCTGTCGTCGTCGCCCGATGCGATCGCCGACGCGGTCAGGCGGATGTACACCGATCCGAACCACTTGCGCGTGTCC
GATCCGGGAACGGTTGAAGGCAACGTGGTGTTCACGTATCTCGACGCGTTCGACGGCGAGCCCGACGAGCTCGAGCGGCT
GAAGGCCGCGTATCGCGCGGGCGGCCTCGGCGACATGGTGCTCAAGCGCCGGCTCGAGGACAGGCTGCAGGCGTTGATCG
CGCCGATCCGCGAGCGGCGCGCGCAGCTCGCGCGCGATCCGGGCTACGTCGTCGACGTGCTGAAGGACGGCACCGCGCAC
GCACGCGACGTCACGCAGCGCACGCTCGACGAGGTGCGCGATGCCCTGGGCGCGTTTTCGTTCCGGCGGTTCGTCGGTTG
A

Upstream 100 bases:

>100_bases
ACATCCCGATCACGACCATGCCGCCGCATCCGGCCGGCATCGCGTCGATCGCGCCCCCAACCCGGCTCGGACTGCGGCGG
TTTTCCCGGAGAAACCGCTC

Downstream 100 bases:

>100_bases
CGAGCGCGACGCGCGGGCGGTCGGCGCATCGCGGCGGTGGGCAGCGGGCTCGCCGCTTCCCAATCTCGGCGCGCCCGAGG
TTCGGCCTTCGATGTCGGAC

Product: tryptophanyl-tRNA synthetase II

Products: NA

Alternate protein names: Tryptophan--tRNA ligase; TrpRS [H]

Number of amino acids: Translated: 346; Mature: 346

Protein sequence:

>346_residues
MHDDTSNPSRAPIALTGDRPTGALHLGHYIGSLKTRIALQDTHRQFILVADTQALTDNAHDPDKVRRNVIEVALDYLAVG
IDPRRSTIAVQSGLPALAELTLFYLNFVTVARLERNPTIKDEIHARGFGRDIPAGFLCYPVAQAADITAFKADTVPVGDD
QLPLIEQTNEIVRRVNRQAGADVLPEASALISPTGRLPGVDGKAKMSKSQGNAIALSSSPDAIADAVRRMYTDPNHLRVS
DPGTVEGNVVFTYLDAFDGEPDELERLKAAYRAGGLGDMVLKRRLEDRLQALIAPIRERRAQLARDPGYVVDVLKDGTAH
ARDVTQRTLDEVRDALGAFSFRRFVG

Sequences:

>Translated_346_residues
MHDDTSNPSRAPIALTGDRPTGALHLGHYIGSLKTRIALQDTHRQFILVADTQALTDNAHDPDKVRRNVIEVALDYLAVG
IDPRRSTIAVQSGLPALAELTLFYLNFVTVARLERNPTIKDEIHARGFGRDIPAGFLCYPVAQAADITAFKADTVPVGDD
QLPLIEQTNEIVRRVNRQAGADVLPEASALISPTGRLPGVDGKAKMSKSQGNAIALSSSPDAIADAVRRMYTDPNHLRVS
DPGTVEGNVVFTYLDAFDGEPDELERLKAAYRAGGLGDMVLKRRLEDRLQALIAPIRERRAQLARDPGYVVDVLKDGTAH
ARDVTQRTLDEVRDALGAFSFRRFVG
>Mature_346_residues
MHDDTSNPSRAPIALTGDRPTGALHLGHYIGSLKTRIALQDTHRQFILVADTQALTDNAHDPDKVRRNVIEVALDYLAVG
IDPRRSTIAVQSGLPALAELTLFYLNFVTVARLERNPTIKDEIHARGFGRDIPAGFLCYPVAQAADITAFKADTVPVGDD
QLPLIEQTNEIVRRVNRQAGADVLPEASALISPTGRLPGVDGKAKMSKSQGNAIALSSSPDAIADAVRRMYTDPNHLRVS
DPGTVEGNVVFTYLDAFDGEPDELERLKAAYRAGGLGDMVLKRRLEDRLQALIAPIRERRAQLARDPGYVVDVLKDGTAH
ARDVTQRTLDEVRDALGAFSFRRFVG

Specific function: Unknown

COG id: COG0180

COG function: function code J; Tryptophanyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI7710154, Length=330, Percent_Identity=27.5757575757576, Blast_Score=125, Evalue=8e-29,
Organism=Homo sapiens, GI41352700, Length=180, Percent_Identity=30, Blast_Score=92, Evalue=6e-19,
Organism=Escherichia coli, GI1789786, Length=334, Percent_Identity=29.6407185628743, Blast_Score=138, Evalue=5e-34,
Organism=Caenorhabditis elegans, GI71982800, Length=350, Percent_Identity=27.4285714285714, Blast_Score=123, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI71982793, Length=350, Percent_Identity=27.4285714285714, Blast_Score=123, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6320474, Length=343, Percent_Identity=26.2390670553936, Blast_Score=103, Evalue=6e-23,
Organism=Drosophila melanogaster, GI24666151, Length=333, Percent_Identity=30.03003003003, Blast_Score=133, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR002305
- InterPro:   IPR014729
- InterPro:   IPR002306 [H]

Pfam domain/function: PF00579 tRNA-synt_1b [H]

EC number: =6.1.1.2 [H]

Molecular weight: Translated: 37758; Mature: 37758

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHDDTSNPSRAPIALTGDRPTGALHLGHYIGSLKTRIALQDTHRQFILVADTQALTDNAH
CCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHEEEEECCCEEEEEECCHHHCCCCC
DPDKVRRNVIEVALDYLAVGIDPRRSTIAVQSGLPALAELTLFYLNFVTVARLERNPTIK
CHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCHH
DEIHARGFGRDIPAGFLCYPVAQAADITAFKADTVPVGDDQLPLIEQTNEIVRRVNRQAG
HHHHHCCCCCCCCCCHHHHHHHHHCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCC
ADVLPEASALISPTGRLPGVDGKAKMSKSQGNAIALSSSPDAIADAVRRMYTDPNHLRVS
CCCCCCCHHHCCCCCCCCCCCCHHHHCCCCCCEEEECCCCHHHHHHHHHHCCCCCCEEEC
DPGTVEGNVVFTYLDAFDGEPDELERLKAAYRAGGLGDMVLKRRLEDRLQALIAPIRERR
CCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
AQLARDPGYVVDVLKDGTAHARDVTQRTLDEVRDALGAFSFRRFVG
HHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MHDDTSNPSRAPIALTGDRPTGALHLGHYIGSLKTRIALQDTHRQFILVADTQALTDNAH
CCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHEEEEECCCEEEEEECCHHHCCCCC
DPDKVRRNVIEVALDYLAVGIDPRRSTIAVQSGLPALAELTLFYLNFVTVARLERNPTIK
CHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCHH
DEIHARGFGRDIPAGFLCYPVAQAADITAFKADTVPVGDDQLPLIEQTNEIVRRVNRQAG
HHHHHCCCCCCCCCCHHHHHHHHHCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCC
ADVLPEASALISPTGRLPGVDGKAKMSKSQGNAIALSSSPDAIADAVRRMYTDPNHLRVS
CCCCCCCHHHCCCCCCCCCCCCHHHHCCCCCCEEEECCCCHHHHHHHHHHCCCCCCEEEC
DPGTVEGNVVFTYLDAFDGEPDELERLKAAYRAGGLGDMVLKRRLEDRLQALIAPIRERR
CCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
AQLARDPGYVVDVLKDGTAHARDVTQRTLDEVRDALGAFSFRRFVG
HHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA