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The map label for this gene is lrp [H]

Identifier: 76818728

GI number: 76818728

Start: 494583

End: 495092

Strand: Direct

Name: lrp [H]

Synonym: BURPS1710b_A0345

Alternate gene names: 76818728

Gene position: 494583-495092 (Clockwise)

Preceding gene: 76817421

Following gene: 76819463

Centisome position: 15.54

GC content: 66.27

Gene sequence:

>510_bases
ATGCGCGCAACAAAAAAATCCTCACCGAAGGCCGCCGCCCCACCGGCGGGCGTGGACATCGACCGCGTCGATCGCGCGAT
CCTCCGCGTGCTGCAGCGCGACGCGTCGGTCTCGAACGTCGCGCTCGCCGCGAAGGTGAACCTGAGCCCGCCCGCGTGCC
TGCGCCGCGTCGAGCGGCTGAAGGAAATGGGGCTGATCCGCGGGATCGTCGCGCTGCTCGAGCCGAAGGCGCTGAATGCG
GGGATGCTCGTGATGATCGGCGTCGTGCTCGACCGCTCGACGCCCGACTCGTTCGGCGCGTTCGAGCAGGCCGCGCAGAA
GGTGTCGGGCTGCATGGAATGCCACGTCGTGACGGGCGAGTTCGACTACATCATGCTGATCCGCACGCGCGACAGCGATA
CGTTCAACCGGCTGCACGCCGAGCAGTTGCTGTACCTGCCCGGCGTGCGGCAGATCCGCACGTTCGTCGTGCTCAAGGAG
ATTCTGTCGACGACGAGTTTTCCGATTTGA

Upstream 100 bases:

>100_bases
AAAACGATCGGGAATAACAGGGTTGCGAATATATTTCCACTTTCCTATTTTTATACTTTTCAATCAGAATTCACGTTAAT
TAAATTAGGAATCGTTCAGC

Downstream 100 bases:

>100_bases
GCCGCGCCGCTTTCGCGTGCCGCCCCGCGGACGCGAATCGCGCGCCGAACGCGCCGTCGGCGGCCCGGTGCGCGCCGCCG
ACGGCGCATGCATGCCGCCA

Product: Lrp regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 169; Mature: 169

Protein sequence:

>169_residues
MRATKKSSPKAAAPPAGVDIDRVDRAILRVLQRDASVSNVALAAKVNLSPPACLRRVERLKEMGLIRGIVALLEPKALNA
GMLVMIGVVLDRSTPDSFGAFEQAAQKVSGCMECHVVTGEFDYIMLIRTRDSDTFNRLHAEQLLYLPGVRQIRTFVVLKE
ILSTTSFPI

Sequences:

>Translated_169_residues
MRATKKSSPKAAAPPAGVDIDRVDRAILRVLQRDASVSNVALAAKVNLSPPACLRRVERLKEMGLIRGIVALLEPKALNA
GMLVMIGVVLDRSTPDSFGAFEQAAQKVSGCMECHVVTGEFDYIMLIRTRDSDTFNRLHAEQLLYLPGVRQIRTFVVLKE
ILSTTSFPI
>Mature_169_residues
MRATKKSSPKAAAPPAGVDIDRVDRAILRVLQRDASVSNVALAAKVNLSPPACLRRVERLKEMGLIRGIVALLEPKALNA
GMLVMIGVVLDRSTPDSFGAFEQAAQKVSGCMECHVVTGEFDYIMLIRTRDSDTFNRLHAEQLLYLPGVRQIRTFVVLKE
ILSTTSFPI

Specific function: Mediates a global response to leucine. Exogenous leucine affects the expression of a number of different operons; lrp mediates this effect for at least some of these operons. For example it is regulator of the branched-chain amino acid transport genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787116, Length=153, Percent_Identity=45.0980392156863, Blast_Score=147, Evalue=4e-37,
Organism=Escherichia coli, GI87081742, Length=150, Percent_Identity=27.3333333333333, Blast_Score=86, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011008
- InterPro:   IPR000485
- InterPro:   IPR019885
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01037 AsnC_trans_reg [H]

EC number: NA

Molecular weight: Translated: 18533; Mature: 18533

Theoretical pI: Translated: 10.03; Mature: 10.03

Prosite motif: PS00519 HTH_ASNC_1 ; PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRATKKSSPKAAAPPAGVDIDRVDRAILRVLQRDASVSNVALAAKVNLSPPACLRRVERL
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHH
KEMGLIRGIVALLEPKALNAGMLVMIGVVLDRSTPDSFGAFEQAAQKVSGCMECHVVTGE
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHEEEEEECC
FDYIMLIRTRDSDTFNRLHAEQLLYLPGVRQIRTFVVLKEILSTTSFPI
CCEEEEEEECCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MRATKKSSPKAAAPPAGVDIDRVDRAILRVLQRDASVSNVALAAKVNLSPPACLRRVERL
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHH
KEMGLIRGIVALLEPKALNAGMLVMIGVVLDRSTPDSFGAFEQAAQKVSGCMECHVVTGE
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHEEEEEECC
FDYIMLIRTRDSDTFNRLHAEQLLYLPGVRQIRTFVVLKEILSTTSFPI
CCEEEEEEECCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]