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The map label for this gene is ydjJ [C]

Identifier: 76818471

GI number: 76818471

Start: 348557

End: 349591

Strand: Direct

Name: ydjJ [C]

Synonym: BURPS1710b_A0234

Alternate gene names: 76818471

Gene position: 348557-349591 (Clockwise)

Preceding gene: 76817653

Following gene: 76819573

Centisome position: 10.95

GC content: 70.43

Gene sequence:

>1035_bases
TTGAAAGCCCTCGTACTCGAAAAGGCGCGCGAGCTCGCGCTGCGCGACATCGATCTGCCGCTCGAGGTCGGCCCCGCCGA
CGTCAAGATCCGCGTCCACACGGTGGGCGTGTGCGGCAGCGATGTCCATTACTACATGCACGGCGGAATCGGCCCGTTCC
GGGTGGACGCGCCGATGGTGCTCGGCCACGAGGCGTCGGGCACGGTCGTCGAGGTCGGGCGCGACGTCACGTACCTGCGC
GTGGGCGAGCGCGTGTGCATGGAGCCCGGCGTGCCGCGCTTCGATTCGAAAGCGACGCTGCACGGCCTGTACAACCTCGA
TCCGTCGGTGCGCTTCTGGGCGACGCCGCCCGTGCACGGGTGCCTCGCGCCCTACGTCGTGCACCCGGCGGCGTTCACGT
ACCGGCTGCCGCCGAACGTGTCGTTCGCCGAGGGCGCGATCGTCGAGCCGCTCGCGATCGGGCTGCAGGCCGCGAAGAAG
GCGGCGATGAAGCCGGGCGACATCGCGGTGGTCGTCGGCGCGGGCACGATCGGCGCGATGACGGCGCTCGCCGCGCTCGC
GGGCGGCGCCGCGCGCGTGATCCTCGCCGACGTCGTCAAGGAAAAGCTCGCGCTGTTCGCCGCGAACCGCGCGGTGACGA
CGGTCGACGCGAGCACGCAGTCGCTCGCCGACGCAGTCGCGCACGCGACCGACGGCTGGGGCGCGGACGTGGTGTTCGAG
GCAAGCGGCAACGCGAGCGCGTATGCGGGCATCGTCGATCTGCTGTGCCCGAACGGCTGCCTCGTGCTGGTCGGCATGCC
GCTCGCGCCGGTGCCGCTCGATGTCGTTTCGCTGCAGGCGAAGGAGGCGCGCATCGAATCGGTGTTCCGCTACGCGAACG
TCTTCCCGCGCGCGCTCGCGCTGATCGCCTCCGGCGCGATCGACGTGAAGCCGTTCATCTCGCGCACGTTCCCGTTCTCG
GACGGCCTGCGCGCATTCGAGGCGGCGGCGAGCGGCCAGCCGCACGACGTGAAGATTCAGATCGAAATGGATTGA

Upstream 100 bases:

>100_bases
CGTGCTGCTCGCGCTGCCGCCGCTCGTCTTCGTCGGCATGCTCAGCCGCCTGCTGAACTCGATGCTCAAAGGCCGATAGT
CGGCCGCCAAGGAGAATCCG

Downstream 100 bases:

>100_bases
GCGATGGCACGGATCGTCTGCACCGGCTTGACCAAACGCTACGACGGCGGCGCGCCCGTCCTGCATCCGCTCGATCTCGA
AATCGGCGACGGCGAGTTCA

Product: zinc-binding dehydrogenase family oxidoreductase

Products: NA

Alternate protein names: Xylitol dehydrogenase; XDH [H]

Number of amino acids: Translated: 344; Mature: 344

Protein sequence:

>344_residues
MKALVLEKARELALRDIDLPLEVGPADVKIRVHTVGVCGSDVHYYMHGGIGPFRVDAPMVLGHEASGTVVEVGRDVTYLR
VGERVCMEPGVPRFDSKATLHGLYNLDPSVRFWATPPVHGCLAPYVVHPAAFTYRLPPNVSFAEGAIVEPLAIGLQAAKK
AAMKPGDIAVVVGAGTIGAMTALAALAGGAARVILADVVKEKLALFAANRAVTTVDASTQSLADAVAHATDGWGADVVFE
ASGNASAYAGIVDLLCPNGCLVLVGMPLAPVPLDVVSLQAKEARIESVFRYANVFPRALALIASGAIDVKPFISRTFPFS
DGLRAFEAAASGQPHDVKIQIEMD

Sequences:

>Translated_344_residues
MKALVLEKARELALRDIDLPLEVGPADVKIRVHTVGVCGSDVHYYMHGGIGPFRVDAPMVLGHEASGTVVEVGRDVTYLR
VGERVCMEPGVPRFDSKATLHGLYNLDPSVRFWATPPVHGCLAPYVVHPAAFTYRLPPNVSFAEGAIVEPLAIGLQAAKK
AAMKPGDIAVVVGAGTIGAMTALAALAGGAARVILADVVKEKLALFAANRAVTTVDASTQSLADAVAHATDGWGADVVFE
ASGNASAYAGIVDLLCPNGCLVLVGMPLAPVPLDVVSLQAKEARIESVFRYANVFPRALALIASGAIDVKPFISRTFPFS
DGLRAFEAAASGQPHDVKIQIEMD
>Mature_344_residues
MKALVLEKARELALRDIDLPLEVGPADVKIRVHTVGVCGSDVHYYMHGGIGPFRVDAPMVLGHEASGTVVEVGRDVTYLR
VGERVCMEPGVPRFDSKATLHGLYNLDPSVRFWATPPVHGCLAPYVVHPAAFTYRLPPNVSFAEGAIVEPLAIGLQAAKK
AAMKPGDIAVVVGAGTIGAMTALAALAGGAARVILADVVKEKLALFAANRAVTTVDASTQSLADAVAHATDGWGADVVFE
ASGNASAYAGIVDLLCPNGCLVLVGMPLAPVPLDVVSLQAKEARIESVFRYANVFPRALALIASGAIDVKPFISRTFPFS
DGLRAFEAAASGQPHDVKIQIEMD

Specific function: Unknown

COG id: COG1063

COG function: function code ER; Threonine dehydrogenase and related Zn-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI156627571, Length=346, Percent_Identity=40.7514450867052, Blast_Score=241, Evalue=5e-64,
Organism=Escherichia coli, GI1788073, Length=314, Percent_Identity=36.9426751592357, Blast_Score=202, Evalue=2e-53,
Organism=Escherichia coli, GI1790045, Length=341, Percent_Identity=29.9120234604106, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI1790718, Length=321, Percent_Identity=29.595015576324, Blast_Score=131, Evalue=7e-32,
Organism=Escherichia coli, GI1787863, Length=343, Percent_Identity=28.5714285714286, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI226510992, Length=334, Percent_Identity=27.8443113772455, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1788075, Length=347, Percent_Identity=26.8011527377522, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1788407, Length=302, Percent_Identity=26.8211920529801, Blast_Score=95, Evalue=8e-21,
Organism=Escherichia coli, GI87082125, Length=270, Percent_Identity=27.7777777777778, Blast_Score=73, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17562876, Length=340, Percent_Identity=37.9411764705882, Blast_Score=237, Evalue=6e-63,
Organism=Caenorhabditis elegans, GI17562878, Length=312, Percent_Identity=36.5384615384615, Blast_Score=209, Evalue=2e-54,
Organism=Saccharomyces cerevisiae, GI6322619, Length=332, Percent_Identity=41.566265060241, Blast_Score=236, Evalue=3e-63,
Organism=Saccharomyces cerevisiae, GI6319955, Length=332, Percent_Identity=41.566265060241, Blast_Score=236, Evalue=3e-63,
Organism=Saccharomyces cerevisiae, GI6323099, Length=347, Percent_Identity=37.463976945245, Blast_Score=234, Evalue=2e-62,
Organism=Saccharomyces cerevisiae, GI6319257, Length=338, Percent_Identity=26.9230769230769, Blast_Score=94, Evalue=4e-20,
Organism=Saccharomyces cerevisiae, GI6319258, Length=379, Percent_Identity=26.1213720316623, Blast_Score=91, Evalue=4e-19,
Organism=Drosophila melanogaster, GI17137530, Length=342, Percent_Identity=36.2573099415205, Blast_Score=206, Evalue=2e-53,
Organism=Drosophila melanogaster, GI17737897, Length=343, Percent_Identity=36.734693877551, Blast_Score=203, Evalue=1e-52,
Organism=Drosophila melanogaster, GI221457811, Length=307, Percent_Identity=32.5732899022801, Blast_Score=137, Evalue=1e-32,
Organism=Drosophila melanogaster, GI45550770, Length=307, Percent_Identity=32.5732899022801, Blast_Score=137, Evalue=1e-32,
Organism=Drosophila melanogaster, GI45551930, Length=307, Percent_Identity=32.5732899022801, Blast_Score=137, Evalue=1e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.1.1.9 [H]

Molecular weight: Translated: 36038; Mature: 36038

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: PS00059 ADH_ZINC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKALVLEKARELALRDIDLPLEVGPADVKIRVHTVGVCGSDVHYYMHGGIGPFRVDAPMV
CCCHHHHHHHHHHHHCCCCCEEECCCCEEEEEEEEEECCCCEEEEEECCCCCEEECCCEE
LGHEASGTVVEVGRDVTYLRVGERVCMEPGVPRFDSKATLHGLYNLDPSVRFWATPPVHG
ECCCCCCCEEEECCCEEEEEECCHHHCCCCCCCCCCCEEEEEEECCCCCEEEEECCCCCH
CLAPYVVHPAAFTYRLPPNVSFAEGAIVEPLAIGLQAAKKAAMKPGDIAVVVGAGTIGAM
HHHHHEECCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHH
TALAALAGGAARVILADVVKEKLALFAANRAVTTVDASTQSLADAVAHATDGWGADVVFE
HHHHHHCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHCCCCCCCEEEEE
ASGNASAYAGIVDLLCPNGCLVLVGMPLAPVPLDVVSLQAKEARIESVFRYANVFPRALA
CCCCCCHHHHHHHHHCCCCEEEEEECCCCCCCHHHEEHHHHHHHHHHHHHHHHHHHHHHH
LIASGAIDVKPFISRTFPFSDGLRAFEAAASGQPHDVKIQIEMD
HHHCCCCCCCHHHHHCCCCCCCHHHHHHHCCCCCCEEEEEEEEC
>Mature Secondary Structure
MKALVLEKARELALRDIDLPLEVGPADVKIRVHTVGVCGSDVHYYMHGGIGPFRVDAPMV
CCCHHHHHHHHHHHHCCCCCEEECCCCEEEEEEEEEECCCCEEEEEECCCCCEEECCCEE
LGHEASGTVVEVGRDVTYLRVGERVCMEPGVPRFDSKATLHGLYNLDPSVRFWATPPVHG
ECCCCCCCEEEECCCEEEEEECCHHHCCCCCCCCCCCEEEEEEECCCCCEEEEECCCCCH
CLAPYVVHPAAFTYRLPPNVSFAEGAIVEPLAIGLQAAKKAAMKPGDIAVVVGAGTIGAM
HHHHHEECCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHH
TALAALAGGAARVILADVVKEKLALFAANRAVTTVDASTQSLADAVAHATDGWGADVVFE
HHHHHHCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHCCCCCCCEEEEE
ASGNASAYAGIVDLLCPNGCLVLVGMPLAPVPLDVVSLQAKEARIESVFRYANVFPRALA
CCCCCCHHHHHHHHHCCCCEEEEEECCCCCCCHHHEEHHHHHHHHHHHHHHHHHHHHHHH
LIASGAIDVKPFISRTFPFSDGLRAFEAAASGQPHDVKIQIEMD
HHHCCCCCCCHHHHHCCCCCCCHHHHHHHCCCCCCEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11214968 [H]