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The map label for this gene is tsaR [H]

Identifier: 76818407

GI number: 76818407

Start: 2033345

End: 2034361

Strand: Direct

Name: tsaR [H]

Synonym: BURPS1710b_A1663

Alternate gene names: 76818407

Gene position: 2033345-2034361 (Clockwise)

Preceding gene: 162210119

Following gene: 76819261

Centisome position: 63.91

GC content: 68.04

Gene sequence:

>1017_bases
GTGCACCATAAGCTGATAAATTGCGTCGGTGCTCACCGCAGGTTGCCTCTAGGGAACACCCTGATTCGCCGCGGCGCAGC
CGATCAACGGCTTTCACGAACCGCGCGTTTTCCCATGAAATATCATCAGTTGAAAGCGTTCGTCGCCGTGGCCGACGAAG
GCAGCATCCGCGCGGCGGCGCGCCGGCTGAACGTATCGCCGGCCGCATTGACGAAGGCCGTGAAGGAACTCGAGCTCGCG
CTCGGCGTATCGCTCGTCGTGCGCACCGCGCGCGGCGTGCAGCTCACCCGCTTCGGCCAGCAGTTGCAGGTGCGCGCGAG
CCTGATCGTCGCCGAGATGCAGCGCGCGCGCGACGATATCGAGCAGGCGCAGGGCGCGACGACGGGCGCCGTTGCCGCCG
CGATCACGCCGGCCGCCGCGGTGACGATCCTGCCGGATGCGTTTCGCGCGTTTCGCCGGCGGTTTCCGCTCGCGCGCGTG
AGCATCGTCGAAGGGTTTCCCGGCGTCGCACTGCCGAAGCTGCACGACGGCTCGCTCGATTTCGCTGTGTCGGTGGTGGT
GCCGGAGCTGCTCGCCGCGGAATTCGAGCACGCGCAGCTGTACGCGAGCCGGCACGTGATCGTCGCGCGCAACGCGCATC
CGCTCGCGGCGGCGACGTCGCTCGCCGATCTCGTCGATGCCGACTGGCTGATGAATCCGTCGCCCGAAAGTTCGACGCAA
CTGATGTTCAACTGTTTCGCCGAGCATGGCTTGCCGGCGCCGACGCGCGTCGTCGAGTGCCCGAGCTACGCGATCGCGCA
CAGCCTCATTCAGGGCTCCGATCTGATTGCGTCGATGCCCGAGCAACTGCTCGGCGTCGAATGGTCGCGCGACCGGATCG
CCGTGCTGCCGATACGGGAGGCGCTGCCGGCCGCATCCGTGCAAGTGGTGACGCGCCGCGACAGCCCGCTGACGCCCGCC
GCGGCGATGCTCGTCGATTGCATGCGCGACGCGGCGCGGCGGCATGGCTTGCGTTGA

Upstream 100 bases:

>100_bases
GGGGATGACGGGGTGTTCGGACGGGGCGGAATGCATGCTGTCTCCTCGTGGGGCTGGGGGCGCTTGCGCGACATGTCGAC
GAAGCATATGAACTTTTTTT

Downstream 100 bases:

>100_bases
CGCGCGCCGCGCGCGCGGGTTGCCCTCGGCGGAGGTGGGCGGCTCGATGGGCGCTGCTTATGCGCAGCCTTTGGCCTAAG
GGCTGCTTGCAGGCGGAACA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MHHKLINCVGAHRRLPLGNTLIRRGAADQRLSRTARFPMKYHQLKAFVAVADEGSIRAAARRLNVSPAALTKAVKELELA
LGVSLVVRTARGVQLTRFGQQLQVRASLIVAEMQRARDDIEQAQGATTGAVAAAITPAAAVTILPDAFRAFRRRFPLARV
SIVEGFPGVALPKLHDGSLDFAVSVVVPELLAAEFEHAQLYASRHVIVARNAHPLAAATSLADLVDADWLMNPSPESSTQ
LMFNCFAEHGLPAPTRVVECPSYAIAHSLIQGSDLIASMPEQLLGVEWSRDRIAVLPIREALPAASVQVVTRRDSPLTPA
AAMLVDCMRDAARRHGLR

Sequences:

>Translated_338_residues
MHHKLINCVGAHRRLPLGNTLIRRGAADQRLSRTARFPMKYHQLKAFVAVADEGSIRAAARRLNVSPAALTKAVKELELA
LGVSLVVRTARGVQLTRFGQQLQVRASLIVAEMQRARDDIEQAQGATTGAVAAAITPAAAVTILPDAFRAFRRRFPLARV
SIVEGFPGVALPKLHDGSLDFAVSVVVPELLAAEFEHAQLYASRHVIVARNAHPLAAATSLADLVDADWLMNPSPESSTQ
LMFNCFAEHGLPAPTRVVECPSYAIAHSLIQGSDLIASMPEQLLGVEWSRDRIAVLPIREALPAASVQVVTRRDSPLTPA
AAMLVDCMRDAARRHGLR
>Mature_338_residues
MHHKLINCVGAHRRLPLGNTLIRRGAADQRLSRTARFPMKYHQLKAFVAVADEGSIRAAARRLNVSPAALTKAVKELELA
LGVSLVVRTARGVQLTRFGQQLQVRASLIVAEMQRARDDIEQAQGATTGAVAAAITPAAAVTILPDAFRAFRRRFPLARV
SIVEGFPGVALPKLHDGSLDFAVSVVVPELLAAEFEHAQLYASRHVIVARNAHPLAAATSLADLVDADWLMNPSPESSTQ
LMFNCFAEHGLPAPTRVVECPSYAIAHSLIQGSDLIASMPEQLLGVEWSRDRIAVLPIREALPAASVQVVTRRDSPLTPA
AAMLVDCMRDAARRHGLR

Specific function: Could be the regulator of the abg operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787601, Length=293, Percent_Identity=32.7645051194539, Blast_Score=168, Evalue=5e-43,
Organism=Escherichia coli, GI1789506, Length=299, Percent_Identity=25.4180602006689, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI87081904, Length=295, Percent_Identity=22.7118644067797, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI145693105, Length=173, Percent_Identity=28.9017341040462, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1790399, Length=294, Percent_Identity=25.1700680272109, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1786401, Length=123, Percent_Identity=34.9593495934959, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788887, Length=182, Percent_Identity=30.2197802197802, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1790208, Length=146, Percent_Identity=30.1369863013699, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1788297, Length=146, Percent_Identity=32.8767123287671, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI157672245, Length=248, Percent_Identity=27.4193548387097, Blast_Score=65, Evalue=9e-12,
Organism=Escherichia coli, GI1788748, Length=149, Percent_Identity=30.8724832214765, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 36556; Mature: 36556

Theoretical pI: Translated: 10.42; Mature: 10.42

Prosite motif: PS50931 HTH_LYSR ; PS00290 IG_MHC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHHKLINCVGAHRRLPLGNTLIRRGAADQRLSRTARFPMKYHQLKAFVAVADEGSIRAAA
CCCHHHHHHHHCCCCCCCHHHHHCCCHHHHHHHHHCCCHHHHHHHHHEEECCCCCHHHHH
RRLNVSPAALTKAVKELELALGVSLVVRTARGVQLTRFGQQLQVRASLIVAEMQRARDDI
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
EQAQGATTGAVAAAITPAAAVTILPDAFRAFRRRFPLARVSIVEGFPGVALPKLHDGSLD
HHHCCCCHHHHHHHHCCHHHEEECHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCCCCCCH
FAVSVVVPELLAAEFEHAQLYASRHVIVARNAHPLAAATSLADLVDADWLMNPSPESSTQ
HHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCHHH
LMFNCFAEHGLPAPTRVVECPSYAIAHSLIQGSDLIASMPEQLLGVEWSRDRIAVLPIRE
HHHHHHHHCCCCCCCCEEECCCHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCEEEEEHHH
ALPAASVQVVTRRDSPLTPAAAMLVDCMRDAARRHGLR
HCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MHHKLINCVGAHRRLPLGNTLIRRGAADQRLSRTARFPMKYHQLKAFVAVADEGSIRAAA
CCCHHHHHHHHCCCCCCCHHHHHCCCHHHHHHHHHCCCHHHHHHHHHEEECCCCCHHHHH
RRLNVSPAALTKAVKELELALGVSLVVRTARGVQLTRFGQQLQVRASLIVAEMQRARDDI
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
EQAQGATTGAVAAAITPAAAVTILPDAFRAFRRRFPLARVSIVEGFPGVALPKLHDGSLD
HHHCCCCHHHHHHHHCCHHHEEECHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCCCCCCH
FAVSVVVPELLAAEFEHAQLYASRHVIVARNAHPLAAATSLADLVDADWLMNPSPESSTQ
HHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCHHH
LMFNCFAEHGLPAPTRVVECPSYAIAHSLIQGSDLIASMPEQLLGVEWSRDRIAVLPIRE
HHHHHHHHCCCCCCCCEEECCCHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCEEEEEHHH
ALPAASVQVVTRRDSPLTPAAAMLVDCMRDAARRHGLR
HCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 9829935 [H]