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The map label for this gene is pphA [H]

Identifier: 76817986

GI number: 76817986

Start: 1161324

End: 1162058

Strand: Direct

Name: pphA [H]

Synonym: BURPS1710b_A0903

Alternate gene names: 76817986

Gene position: 1161324-1162058 (Clockwise)

Preceding gene: 76818036

Following gene: 76817652

Centisome position: 36.5

GC content: 71.29

Gene sequence:

>735_bases
ATGGACACTGCTCCCCTGATCCGTCGCCATACCGCAAACCACGCCGGCCGCGATTTCGTCGTCGGCGATCTGCACGGTTG
CGTCGATCCGCTGCGCGCGCTGCTGCACACCGTGCGCTTCGATCCGGCACGCGACCGGCTGTTCTCGGTGGGCGACCTCG
TCGACCGCGGCGCGCAATCGGAAGCGGCGCTCGCGCTGCTCGAGCGCCCGTGGTTTCATTGCGTGCTCGGCAACCACGAA
GACGTGCTGTGCTCGGTCGCGGACGGCAAGCTGCCGATGAGCGTGTGGCAGCGCATCGGCGGCGAATGGGCGGCCGACCT
GCCGGCCGCGACGCTCGCGCGCCATGCGCGGCGGTTGCGCGAGTTGCCCCTCGTGCGCGTCGTCGGCGAAGGCGACGCGC
GCTTCAACGTGCTGCACGCGGAGTTCTTCGGCAGCGACGCCGACCTCGACCGCGGCGATTACGCGCCCGACGTGATCACG
CGGCTGCTGTGGGGCCGCGAGCTGGCGTACGGGCGCACCGACCCGGCCGCGCGGCAGGCCGGGCTGTCGACCACTTACTG
CGGCCATACGCCGATGCATGATGTCGTGCGCATCGGCGCGCAGACGTTCGTCGATACGGGCGCGTTCGATCCGTCGGGCC
GGCTCACGTTGCTCGACGCGAAGAGCGGCGAAAGCTGGTCGATGTCGGTTGCGGCCGCGCGCCACCAGGGCGCCGCCGAC
GTGCCGCTGCCGTGA

Upstream 100 bases:

>100_bases
AAAGTCGGGTGAAAGAACGCGCCGCTGTTGCGGCGCGTCGCAGCGATTATCGTCACGTTCTCCCGCTGCGCCAAGCCCGG
CTGTGTCCTAAGATGGGCGA

Downstream 100 bases:

>100_bases
CGCGCGGAAGCCGGACGGAGCCGACGCACGGCGCCCGGCGCCCGACGCGCTGCGTCGAGACTGCGCGCAAGCGCGACGGC
GGCGCAAACCGCACGCCGCC

Product: phosphoprotein phosphatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 244; Mature: 244

Protein sequence:

>244_residues
MDTAPLIRRHTANHAGRDFVVGDLHGCVDPLRALLHTVRFDPARDRLFSVGDLVDRGAQSEAALALLERPWFHCVLGNHE
DVLCSVADGKLPMSVWQRIGGEWAADLPAATLARHARRLRELPLVRVVGEGDARFNVLHAEFFGSDADLDRGDYAPDVIT
RLLWGRELAYGRTDPAARQAGLSTTYCGHTPMHDVVRIGAQTFVDTGAFDPSGRLTLLDAKSGESWSMSVAAARHQGAAD
VPLP

Sequences:

>Translated_244_residues
MDTAPLIRRHTANHAGRDFVVGDLHGCVDPLRALLHTVRFDPARDRLFSVGDLVDRGAQSEAALALLERPWFHCVLGNHE
DVLCSVADGKLPMSVWQRIGGEWAADLPAATLARHARRLRELPLVRVVGEGDARFNVLHAEFFGSDADLDRGDYAPDVIT
RLLWGRELAYGRTDPAARQAGLSTTYCGHTPMHDVVRIGAQTFVDTGAFDPSGRLTLLDAKSGESWSMSVAAARHQGAAD
VPLP
>Mature_244_residues
MDTAPLIRRHTANHAGRDFVVGDLHGCVDPLRALLHTVRFDPARDRLFSVGDLVDRGAQSEAALALLERPWFHCVLGNHE
DVLCSVADGKLPMSVWQRIGGEWAADLPAATLARHARRLRELPLVRVVGEGDARFNVLHAEFFGSDADLDRGDYAPDVIT
RLLWGRELAYGRTDPAARQAGLSTTYCGHTPMHDVVRIGAQTFVDTGAFDPSGRLTLLDAKSGESWSMSVAAARHQGAAD
VPLP

Specific function: Plays a key role in signaling protein misfolding via the CpxR/CPXA transducing system. It also modulates the phosphorylated status of many phosphoproteins in E.coli, some of which acting as major chaperones. Has been shown, in vitro, to act on Ser, Thr an

COG id: COG0639

COG function: function code T; Diadenosine tetraphosphatase and related serine/threonine protein phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PPP phosphatase family. PP-1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI87081988, Length=222, Percent_Identity=33.3333333333333, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1789090, Length=221, Percent_Identity=28.9592760180996, Blast_Score=90, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004843
- InterPro:   IPR006186 [H]

Pfam domain/function: PF00149 Metallophos [H]

EC number: =3.1.3.16 [H]

Molecular weight: Translated: 26573; Mature: 26573

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTAPLIRRHTANHAGRDFVVGDLHGCVDPLRALLHTVRFDPARDRLFSVGDLVDRGAQS
CCCCHHHHHHHCCCCCCCEEEECHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCH
EAALALLERPWFHCVLGNHEDVLCSVADGKLPMSVWQRIGGEWAADLPAATLARHARRLR
HHHHHHHHCCCEEEEECCCCCEEEEECCCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHH
ELPLVRVVGEGDARFNVLHAEFFGSDADLDRGDYAPDVITRLLWGRELAYGRTDPAARQA
HCCEEEEECCCCCEEEEEEHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHC
GLSTTYCGHTPMHDVVRIGAQTFVDTGAFDPSGRLTLLDAKSGESWSMSVAAARHQGAAD
CCCCEECCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCEEHHHHHHHCCCCCC
VPLP
CCCC
>Mature Secondary Structure
MDTAPLIRRHTANHAGRDFVVGDLHGCVDPLRALLHTVRFDPARDRLFSVGDLVDRGAQS
CCCCHHHHHHHCCCCCCCEEEECHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCH
EAALALLERPWFHCVLGNHEDVLCSVADGKLPMSVWQRIGGEWAADLPAATLARHARRLR
HHHHHHHHCCCEEEEECCCCCEEEEECCCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHH
ELPLVRVVGEGDARFNVLHAEFFGSDADLDRGDYAPDVITRLLWGRELAYGRTDPAARQA
HCCEEEEECCCCCEEEEEEHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHC
GLSTTYCGHTPMHDVVRIGAQTFVDTGAFDPSGRLTLLDAKSGESWSMSVAAARHQGAAD
CCCCEECCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCEEHHHHHHHCCCCCC
VPLP
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9130712; 9097040; 9278503 [H]