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The map label for this gene is aphA [H]

Identifier: 75910056

GI number: 75910056

Start: 4794640

End: 4796937

Strand: Direct

Name: aphA [H]

Synonym: Ava_3852

Alternate gene names: 75910056

Gene position: 4794640-4796937 (Clockwise)

Preceding gene: 75910055

Following gene: 75910057

Centisome position: 75.32

GC content: 41.12

Gene sequence:

>2298_bases
ATGAGAATAGACTTAGAATCACCCAATATTAATGTTACTAGTTTAAAAGAAGCGCCAATTCATCTTTCCGGACAGATTCA
ACCACATGGTGTGCTTTTGGTTTTAGAAGAACCTGATCTGAAAATATTACAAGTGAGCAACAATACTTGGAGTATTTTGG
GTATCAAGACTGAAGATATATTACAGAAAAAATTAGAAGACTTACTCGATTCATTCCAAATAGAACGAATTCAAGCAGGC
TTATCTTCTGGGAATCTGGAATTTATTAACCCTACGAAAATTTGGATTAGAAAAAAGGGGGATGATTACGCAGTATTTGA
TGCCGTTTTTCATCGCAATACGGAAGGCTTTTTGATTCTGGAGTTAGAACCGGCAATTACTCAAGAAAATATCCCGTTTT
TAAGCTTCTATCATCTGGCTAAAGCTTCAATTAATCAGTTGCAGAAAACAGCTAATCTGCGGGATTTTTGTCAGATAATT
GTCCAAGAAGTCCGCAAAGTCACCGATTTTGATCGGGTAATGTTATATAAGTTCGATGATGATGGACATGGTTCAGTCAT
CGCGGAAGAAAAACTAGACAGCCTAGAACCATACTTAGGACTGCACTATCCAGAATCTGATATACCTAAACCAGCCAGAA
AATTATTTATTTCTAATTCTATTCGGGTGATTCCCAATGCTCAGGCTCAAGCTATACAGATGATACCATCTGTAAATCCA
GTGAGCGATCGCCCGGTTGATTTAACTAACTCAATTCTCAGAAGTGCGGCGAACTGTCACCTGGAATATTTACACAATAT
GGGTGTCGGTGCTTCCTTAACTATTTCCTTAATTAAAGACAATAAGCTTTGGGGATTAATTGCTTGTCACCATCTGTCAG
CCAAGTATGTTTCCTATGAATTGCGGAAAGCCTGCGAATTTTTGGGACGGGTGATATTTGCGGAAATTTCCGCCAGGGAA
GAAACAGAAGATTACGATTATCGGATGAATCTGACCCATATTCAATCTCTGTTGGTTGAATATATGTCCCAAGAAGATAA
CTTTGTTGATGGTTTAGTTAAACATCAGCCGAATCTTTTAGATTTAACCAGCGCCCAAGGTGCGGCGGTATGTTTTGGCG
ACCATTGTACATTAATCGGTGAGACTCCCAAAGCAGAAGATTTAGTTTTCTTAGTCCAGTGGTTGAAGAATAACGTTGAG
GAAGAAGTTTTCTACACTGATTCTCTACCGCAAGTTTATCCAGATGCGGAAAGATATAAAAACGTCGCCAGTGGTTTGTT
AGCGATTCCTATTTCCCAACGTAATTACGTTTTGTGGTTTCGACCGGAAGTAATTCAAACTGTAAACTGGGGTGGTGACC
CTAATCAGCCTTTTGAAGTGAATAAGTTAGATGGGAATGTGCGTCTGTGTCCGCGCAAATCCTTTGAGTTGTGGAAAGAA
ACAGTCCGCCTCACTTCTTTACCTTGGCGATATGTGGAAATTAAAGCGGCTTTAGAATTGCGGAAAGCGATTGTGAACAT
CGTTCTGCGCCAAGCCGATGAACTGGCGCAGTTAGCACAAGATTTAGAACGTTCCAACGCCGAACTGAAAAAGTTTGCTT
ATGTTGCATCCCATGACTTACAAGAACCACTCAATCAAGTAGCGAATTATGTACAGTTGTTGGAGATGCGCTATCAAGAT
GAACTAGATGCCGATGCCAATGAGTTTATCACCTTTGCAGTTGAAGGGGTGAGCTTGATGCAAACCTTAATTGATGACGT
TTTGGCGTATTCTAAAGTAGATACACAAGCGATCGCTTTTCAACTAACAGAAGTAGAAAAAGCCTTAGATAAGGCTTTGG
GTAATTTGCGCCAACGCATCGCCGAAACAGGCGCAACCATTACTCACGACCCCTTACCAACGGTAATGGCTGGTAGTACC
CAACTTATGCAGCTATTCCAGAATTTGATAGCCAACGCCATTAAATTCCACAGTCAGGAAGCGCCGCAAATTCATATAGG
TGCAGAAAGGCTAGAAGACGAATGGCTATTCTCCGTCAGAGATAATGGGATTGGTATTGACCCCCAATTTAGCGATCGGA
TTTTCGTAATTTTCCAACGCTTACACACGCGAGACGAGTATCATGGTACAGGTATGGGCCTAGCAATCTGTAAGAAAATT
ATCGAATGTCACCGGGGACGAATCTGGGTAGAGTCACAACTTGGTGAAGGTGCTACCTTCTACTTTACGATACCAGTTGG
AGGTCGAGAGCGTGAGCGTAGAAACGGAAGAAAAACACAAAACAATCTTTTTAGTTGA

Upstream 100 bases:

>100_bases
AGTAATGGCTTAAATTAAGGAATGTAAATAATTAATTACTTAGCTTAAAAAATATATCGACTCTAATTTTGATGATTCCA
GGGAATCAAAGAGGATTGTT

Downstream 100 bases:

>100_bases
GGACAATAAAGCCGATATCCGCCTTATCCAAGAAGCCTTTAAAAATAGCCAATTACCCCACGAAGTGGTAACAGTGAGAG
ATGGTATGGACGCAATGGCC

Product: multi-sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 765; Mature: 765

Protein sequence:

>765_residues
MRIDLESPNINVTSLKEAPIHLSGQIQPHGVLLVLEEPDLKILQVSNNTWSILGIKTEDILQKKLEDLLDSFQIERIQAG
LSSGNLEFINPTKIWIRKKGDDYAVFDAVFHRNTEGFLILELEPAITQENIPFLSFYHLAKASINQLQKTANLRDFCQII
VQEVRKVTDFDRVMLYKFDDDGHGSVIAEEKLDSLEPYLGLHYPESDIPKPARKLFISNSIRVIPNAQAQAIQMIPSVNP
VSDRPVDLTNSILRSAANCHLEYLHNMGVGASLTISLIKDNKLWGLIACHHLSAKYVSYELRKACEFLGRVIFAEISARE
ETEDYDYRMNLTHIQSLLVEYMSQEDNFVDGLVKHQPNLLDLTSAQGAAVCFGDHCTLIGETPKAEDLVFLVQWLKNNVE
EEVFYTDSLPQVYPDAERYKNVASGLLAIPISQRNYVLWFRPEVIQTVNWGGDPNQPFEVNKLDGNVRLCPRKSFELWKE
TVRLTSLPWRYVEIKAALELRKAIVNIVLRQADELAQLAQDLERSNAELKKFAYVASHDLQEPLNQVANYVQLLEMRYQD
ELDADANEFITFAVEGVSLMQTLIDDVLAYSKVDTQAIAFQLTEVEKALDKALGNLRQRIAETGATITHDPLPTVMAGST
QLMQLFQNLIANAIKFHSQEAPQIHIGAERLEDEWLFSVRDNGIGIDPQFSDRIFVIFQRLHTRDEYHGTGMGLAICKKI
IECHRGRIWVESQLGEGATFYFTIPVGGRERERRNGRKTQNNLFS

Sequences:

>Translated_765_residues
MRIDLESPNINVTSLKEAPIHLSGQIQPHGVLLVLEEPDLKILQVSNNTWSILGIKTEDILQKKLEDLLDSFQIERIQAG
LSSGNLEFINPTKIWIRKKGDDYAVFDAVFHRNTEGFLILELEPAITQENIPFLSFYHLAKASINQLQKTANLRDFCQII
VQEVRKVTDFDRVMLYKFDDDGHGSVIAEEKLDSLEPYLGLHYPESDIPKPARKLFISNSIRVIPNAQAQAIQMIPSVNP
VSDRPVDLTNSILRSAANCHLEYLHNMGVGASLTISLIKDNKLWGLIACHHLSAKYVSYELRKACEFLGRVIFAEISARE
ETEDYDYRMNLTHIQSLLVEYMSQEDNFVDGLVKHQPNLLDLTSAQGAAVCFGDHCTLIGETPKAEDLVFLVQWLKNNVE
EEVFYTDSLPQVYPDAERYKNVASGLLAIPISQRNYVLWFRPEVIQTVNWGGDPNQPFEVNKLDGNVRLCPRKSFELWKE
TVRLTSLPWRYVEIKAALELRKAIVNIVLRQADELAQLAQDLERSNAELKKFAYVASHDLQEPLNQVANYVQLLEMRYQD
ELDADANEFITFAVEGVSLMQTLIDDVLAYSKVDTQAIAFQLTEVEKALDKALGNLRQRIAETGATITHDPLPTVMAGST
QLMQLFQNLIANAIKFHSQEAPQIHIGAERLEDEWLFSVRDNGIGIDPQFSDRIFVIFQRLHTRDEYHGTGMGLAICKKI
IECHRGRIWVESQLGEGATFYFTIPVGGRERERRNGRKTQNNLFS
>Mature_765_residues
MRIDLESPNINVTSLKEAPIHLSGQIQPHGVLLVLEEPDLKILQVSNNTWSILGIKTEDILQKKLEDLLDSFQIERIQAG
LSSGNLEFINPTKIWIRKKGDDYAVFDAVFHRNTEGFLILELEPAITQENIPFLSFYHLAKASINQLQKTANLRDFCQII
VQEVRKVTDFDRVMLYKFDDDGHGSVIAEEKLDSLEPYLGLHYPESDIPKPARKLFISNSIRVIPNAQAQAIQMIPSVNP
VSDRPVDLTNSILRSAANCHLEYLHNMGVGASLTISLIKDNKLWGLIACHHLSAKYVSYELRKACEFLGRVIFAEISARE
ETEDYDYRMNLTHIQSLLVEYMSQEDNFVDGLVKHQPNLLDLTSAQGAAVCFGDHCTLIGETPKAEDLVFLVQWLKNNVE
EEVFYTDSLPQVYPDAERYKNVASGLLAIPISQRNYVLWFRPEVIQTVNWGGDPNQPFEVNKLDGNVRLCPRKSFELWKE
TVRLTSLPWRYVEIKAALELRKAIVNIVLRQADELAQLAQDLERSNAELKKFAYVASHDLQEPLNQVANYVQLLEMRYQD
ELDADANEFITFAVEGVSLMQTLIDDVLAYSKVDTQAIAFQLTEVEKALDKALGNLRQRIAETGATITHDPLPTVMAGST
QLMQLFQNLIANAIKFHSQEAPQIHIGAERLEDEWLFSVRDNGIGIDPQFSDRIFVIFQRLHTRDEYHGTGMGLAICKKI
IECHRGRIWVESQLGEGATFYFTIPVGGRERERRNGRKTQNNLFS

Specific function: Photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region [H]

COG id: COG4251

COG function: function code T; Bacteriophytochrome (light-regulated signal transduction histidine kinase)

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI145693157, Length=256, Percent_Identity=27.734375, Blast_Score=99, Evalue=1e-21,
Organism=Escherichia coli, GI48994928, Length=240, Percent_Identity=31.25, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1788393, Length=248, Percent_Identity=28.2258064516129, Blast_Score=82, Evalue=2e-16,
Organism=Escherichia coli, GI1786600, Length=262, Percent_Identity=28.2442748091603, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1789149, Length=240, Percent_Identity=27.9166666666667, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI87081816, Length=234, Percent_Identity=25.2136752136752, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1786912, Length=249, Percent_Identity=26.5060240963855, Blast_Score=70, Evalue=7e-13,
Organism=Escherichia coli, GI1788549, Length=224, Percent_Identity=25.4464285714286, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1788713, Length=234, Percent_Identity=23.5042735042735, Blast_Score=67, Evalue=6e-12,
Organism=Escherichia coli, GI1790436, Length=236, Percent_Identity=26.271186440678, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI1790346, Length=223, Percent_Identity=26.0089686098655, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR013654
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01590 GAF; PF02518 HATPase_c; PF00512 HisKA; PF08446 PAS_2; PF00360 Phytochrome [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 86977; Mature: 86977

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: PS50109 HIS_KIN ; PS50046 PHYTOCHROME_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIDLESPNINVTSLKEAPIHLSGQIQPHGVLLVLEEPDLKILQVSNNTWSILGIKTEDI
CEEECCCCCCEEEEECCCCEEEECEECCCEEEEEEECCCEEEEEECCCEEEEEEECHHHH
LQKKLEDLLDSFQIERIQAGLSSGNLEFINPTKIWIRKKGDDYAVFDAVFHRNTEGFLIL
HHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCEEEEEECCCCEEHHHHHHHCCCCCEEEE
ELEPAITQENIPFLSFYHLAKASINQLQKTANLRDFCQIIVQEVRKVTDFDRVMLYKFDD
EECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCEEEEEEECC
DGHGSVIAEEKLDSLEPYLGLHYPESDIPKPARKLFISNSIRVIPNAQAQAIQMIPSVNP
CCCCCEEEHHHHHHCCCHHCCCCCCCCCCCHHHHHHHCCCEEEECCCHHHHHHHCCCCCC
VSDRPVDLTNSILRSAANCHLEYLHNMGVGASLTISLIKDNKLWGLIACHHLSAKYVSYE
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCEEEEEEHHHHHHHHHHHH
LRKACEFLGRVIFAEISAREETEDYDYRMNLTHIQSLLVEYMSQEDNFVDGLVKHQPNLL
HHHHHHHHHHHHHHHHHCCCCCCCCCEEECHHHHHHHHHHHHCCCCCHHHHHHHCCCCEE
DLTSAQGAAVCFGDHCTLIGETPKAEDLVFLVQWLKNNVEEEVFYTDSLPQVYPDAERYK
EECCCCCCEEEECCCEEEECCCCCHHHHHHHHHHHHCCCCHHEEEECCCCCCCCCHHHHH
NVASGLLAIPISQRNYVLWFRPEVIQTVNWGGDPNQPFEVNKLDGNVRLCPRKSFELWKE
HHHCCEEEEEECCCCEEEEECHHHHHEECCCCCCCCCEEEEECCCCEEECCCCHHHHHHH
TVRLTSLPWRYVEIKAALELRKAIVNIVLRQADELAQLAQDLERSNAELKKFAYVASHDL
HHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
QEPLNQVANYVQLLEMRYQDELDADANEFITFAVEGVSLMQTLIDDVLAYSKVDTQAIAF
HHHHHHHHHHHHHHHHHHHHCCCCCHHHEEEEEEHHHHHHHHHHHHHHHHHCCCHHHHHH
QLTEVEKALDKALGNLRQRIAETGATITHDPLPTVMAGSTQLMQLFQNLIANAIKFHSQE
HHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCHHHCCCHHHHHHHHHHHHHHHHHCCCC
APQIHIGAERLEDEWLFSVRDNGIGIDPQFSDRIFVIFQRLHTRDEYHGTGMGLAICKKI
CCEEEECHHHHCCHHEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHH
IECHRGRIWVESQLGEGATFYFTIPVGGRERERRNGRKTQNNLFS
HHHHCCCEEEEECCCCCEEEEEEECCCCCHHHHHCCCCCHHCCCC
>Mature Secondary Structure
MRIDLESPNINVTSLKEAPIHLSGQIQPHGVLLVLEEPDLKILQVSNNTWSILGIKTEDI
CEEECCCCCCEEEEECCCCEEEECEECCCEEEEEEECCCEEEEEECCCEEEEEEECHHHH
LQKKLEDLLDSFQIERIQAGLSSGNLEFINPTKIWIRKKGDDYAVFDAVFHRNTEGFLIL
HHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCEEEEEECCCCEEHHHHHHHCCCCCEEEE
ELEPAITQENIPFLSFYHLAKASINQLQKTANLRDFCQIIVQEVRKVTDFDRVMLYKFDD
EECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCEEEEEEECC
DGHGSVIAEEKLDSLEPYLGLHYPESDIPKPARKLFISNSIRVIPNAQAQAIQMIPSVNP
CCCCCEEEHHHHHHCCCHHCCCCCCCCCCCHHHHHHHCCCEEEECCCHHHHHHHCCCCCC
VSDRPVDLTNSILRSAANCHLEYLHNMGVGASLTISLIKDNKLWGLIACHHLSAKYVSYE
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCEEEEEEHHHHHHHHHHHH
LRKACEFLGRVIFAEISAREETEDYDYRMNLTHIQSLLVEYMSQEDNFVDGLVKHQPNLL
HHHHHHHHHHHHHHHHHCCCCCCCCCEEECHHHHHHHHHHHHCCCCCHHHHHHHCCCCEE
DLTSAQGAAVCFGDHCTLIGETPKAEDLVFLVQWLKNNVEEEVFYTDSLPQVYPDAERYK
EECCCCCCEEEECCCEEEECCCCCHHHHHHHHHHHHCCCCHHEEEECCCCCCCCCHHHHH
NVASGLLAIPISQRNYVLWFRPEVIQTVNWGGDPNQPFEVNKLDGNVRLCPRKSFELWKE
HHHCCEEEEEECCCCEEEEECHHHHHEECCCCCCCCCEEEEECCCCEEECCCCHHHHHHH
TVRLTSLPWRYVEIKAALELRKAIVNIVLRQADELAQLAQDLERSNAELKKFAYVASHDL
HHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
QEPLNQVANYVQLLEMRYQDELDADANEFITFAVEGVSLMQTLIDDVLAYSKVDTQAIAF
HHHHHHHHHHHHHHHHHHHHCCCCCHHHEEEEEEHHHHHHHHHHHHHHHHHCCCHHHHHH
QLTEVEKALDKALGNLRQRIAETGATITHDPLPTVMAGSTQLMQLFQNLIANAIKFHSQE
HHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCHHHCCCHHHHHHHHHHHHHHHHHCCCC
APQIHIGAERLEDEWLFSVRDNGIGIDPQFSDRIFVIFQRLHTRDEYHGTGMGLAICKKI
CCEEEECHHHHCCHHEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHH
IECHRGRIWVESQLGEGATFYFTIPVGGRERERRNGRKTQNNLFS
HHHHCCCEEEEECCCCCEEEEEEECCCCCHHHHHCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11759840 [H]