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The map label for this gene is degU [H]

Identifier: 75910055

GI number: 75910055

Start: 4793543

End: 4794226

Strand: Direct

Name: degU [H]

Synonym: Ava_3851

Alternate gene names: 75910055

Gene position: 4793543-4794226 (Clockwise)

Preceding gene: 75910054

Following gene: 75910056

Centisome position: 75.3

GC content: 39.77

Gene sequence:

>684_bases
ATGGCTTCTAACCCGGTAAAAATTCTGTTGGTTGAAGATGATGAACTCTTTCGCTTAGGCTTGCGCGTGCGATTACAACA
AGAAGCAGGTTTAGAAATTATTGCTGAGGCTGAAGATGGTGAAACAGCTCTTGATTTAATCAAGCAAAACTCTCTGGATG
TGGTGTTATTAGATGTAGGATTACCAGGGCTGGGGGGAATAGAAGCTTGTAAACAAATTAAGCAGCAAAATCCTCAATTA
CCAATTTTAGTTTTGACTTCCCATTCCCAAAAACCGTTAATTTCTAAATTAATTGAAGCAGGCGCTCAAGGATATTGTCT
CAAAGGAATTATCGCCGAAAAATTAGTATTGGCACTGCGTTCTGTAGCGGCTGGGGCTTCTTGGTGGGATGAAACTGCAA
CTAGGGAAATTCGCTCTTCAATTGAGTCTAGCCAGTCTCAATCGCCAGAACAAAATTTCACAAAATCTGATCACCCTTTA
ACTGGACGTGAATTAGAAATTTTATCTTTATTAGCCAAGGGTAAAACGAATCAGGAAATTGCTACAGCACTCTACATTAC
CCCTGGAACAGTTAGAGTTCATGTTCATGCTATTCTACACAAACTAGAGGTTAGCGATCGCCATCAAGCTGTAGTTGTTG
CTTTACAAAAACGTTTGATTCAAAATAGTGCGATCGCAGATTAA

Upstream 100 bases:

>100_bases
CATAACGGTATAATTTGGGCAGAGAATAGAGTTCCTACGGGTGCTATGTTTGCATTCAAATTGCCTGTTCTCCCATTTCA
GCCCTCCTTATCTGCGTCAG

Downstream 100 bases:

>100_bases
TAGTCAAGTCACTTCACTCCAATTCAAAATTAAAAATTTGGATAAATTTTTTATTCCTGATATGAGGGGCTTGCAGAGTA
AAAAATATCTAAGTGTAGGG

Product: two component LuxR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 227; Mature: 226

Protein sequence:

>227_residues
MASNPVKILLVEDDELFRLGLRVRLQQEAGLEIIAEAEDGETALDLIKQNSLDVVLLDVGLPGLGGIEACKQIKQQNPQL
PILVLTSHSQKPLISKLIEAGAQGYCLKGIIAEKLVLALRSVAAGASWWDETATREIRSSIESSQSQSPEQNFTKSDHPL
TGRELEILSLLAKGKTNQEIATALYITPGTVRVHVHAILHKLEVSDRHQAVVVALQKRLIQNSAIAD

Sequences:

>Translated_227_residues
MASNPVKILLVEDDELFRLGLRVRLQQEAGLEIIAEAEDGETALDLIKQNSLDVVLLDVGLPGLGGIEACKQIKQQNPQL
PILVLTSHSQKPLISKLIEAGAQGYCLKGIIAEKLVLALRSVAAGASWWDETATREIRSSIESSQSQSPEQNFTKSDHPL
TGRELEILSLLAKGKTNQEIATALYITPGTVRVHVHAILHKLEVSDRHQAVVVALQKRLIQNSAIAD
>Mature_226_residues
ASNPVKILLVEDDELFRLGLRVRLQQEAGLEIIAEAEDGETALDLIKQNSLDVVLLDVGLPGLGGIEACKQIKQQNPQLP
ILVLTSHSQKPLISKLIEAGAQGYCLKGIIAEKLVLALRSVAAGASWWDETATREIRSSIESSQSQSPEQNFTKSDHPLT
GRELEILSLLAKGKTNQEIATALYITPGTVRVHVHAILHKLEVSDRHQAVVVALQKRLIQNSAIAD

Specific function: Regulating factor for the production of extracellular proteases. The N-terminal region acts as an inhibitor, whereas the C-terminal region carries enhancing activity [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788222, Length=200, Percent_Identity=35.5, Blast_Score=131, Evalue=4e-32,
Organism=Escherichia coli, GI1788521, Length=216, Percent_Identity=34.7222222222222, Blast_Score=128, Evalue=4e-31,
Organism=Escherichia coli, GI1786747, Length=198, Percent_Identity=26.7676767676768, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1787473, Length=216, Percent_Identity=30.5555555555556, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1790102, Length=201, Percent_Identity=27.363184079602, Blast_Score=77, Evalue=7e-16,
Organism=Escherichia coli, GI1789937, Length=212, Percent_Identity=25, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788712, Length=173, Percent_Identity=22.5433526011561, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 24711; Mature: 24580

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASNPVKILLVEDDELFRLGLRVRLQQEAGLEIIAEAEDGETALDLIKQNSLDVVLLDVG
CCCCCEEEEEECCCHHHHHHHHEEEECCCCCEEEEECCCCHHHHHHHHCCCCCEEEEECC
LPGLGGIEACKQIKQQNPQLPILVLTSHSQKPLISKLIEAGAQGYCLKGIIAEKLVLALR
CCCCCHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHCCCCCEEHHHHHHHHHHHHHH
SVAAGASWWDETATREIRSSIESSQSQSPEQNFTKSDHPLTGRELEILSLLAKGKTNQEI
HHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCE
ATALYITPGTVRVHVHAILHKLEVSDRHQAVVVALQKRLIQNSAIAD
EEEEEECCCEEEEHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
ASNPVKILLVEDDELFRLGLRVRLQQEAGLEIIAEAEDGETALDLIKQNSLDVVLLDVG
CCCCEEEEEECCCHHHHHHHHEEEECCCCCEEEEECCCCHHHHHHHHCCCCCEEEEECC
LPGLGGIEACKQIKQQNPQLPILVLTSHSQKPLISKLIEAGAQGYCLKGIIAEKLVLALR
CCCCCHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHCCCCCEEHHHHHHHHHHHHHH
SVAAGASWWDETATREIRSSIESSQSQSPEQNFTKSDHPLTGRELEILSLLAKGKTNQEI
HHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCE
ATALYITPGTVRVHVHAILHKLEVSDRHQAVVVALQKRLIQNSAIAD
EEEEEECCCEEEEHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7765823 [H]