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The map label for this gene is hemN [H]

Identifier: 75910032

GI number: 75910032

Start: 4764292

End: 4765674

Strand: Direct

Name: hemN [H]

Synonym: Ava_3828

Alternate gene names: 75910032

Gene position: 4764292-4765674 (Clockwise)

Preceding gene: 75910031

Following gene: 75910035

Centisome position: 74.84

GC content: 39.26

Gene sequence:

>1383_bases
ATGGTTTTTGTCTTACCTGGTGTCAAGTTTGATCTAGACATGATCAAAAAATATGACACTCCTGCACCTAGATATACCAG
TTATCCACCCGCTACACAGTTAACTGAAGAATTTAGCGCCACCGATTATCAAAGTGCGATCGCCGCCTCAAATCACAGAA
AATCGCCCATATCGTTGTATTTCCACATTCCTTTTTGTCAAAGTTCCTGTTACTTTTGCGGTTGTAATACGGTTATTTCC
AACAACAAAAATATTGCTAAACCATACTTAGAACATCTGGTAAAAGAAATCAAGCATACAAGTAACTTGATTGATCCAGA
CAGAAAAGTATTACAAGTTCACTGGGGTGGTGGGACACCGAATTACTTAGATTGTGATCAAGTAGAATTTTTGTGGAAAC
ATATTCATCGCCACTTCAATATTGATCCACAGGCAGAAATATCCATTGAGATTAATCCCCGCTACGTTGATCAAAACTAC
ATCTCCTTTTTGCGTGAGATTGGTTTTAACCGGATTAGTTTTGGCATTCAGGATTTTAATAGCCAAGTACAAAAAGCTGT
CAACCGTATCCAACCGGAAGAATTGCTAGTTAATGTCATGAGTTGGATTAAAGCCGCTAAGTTTGACAGTGTAAATGTAG
ACCTAATTTATGGTTTACCTCATCAAACCTTGCAAACATTTCGGGAGACGGTGAAAAAAACCGTGGCATTAGACCCCGAT
CGCATTGTAGTCTTTAACTTTGCTTATGTTCCTTGGTTGAAGCCAGCCCAGAAAAATATTCCCTTGGAGGCGTTACCCCA
ACCGCAGGAAAAGCTGGAAATTTTAAAAATGACTATTGAGGAACTGACTAATAGCCAGTACCTATTTATTGGGATGGATC
ATTTTGCCAAGCATAACGATGAGTTAGCGATCGCCCAACGTAACCACACCCTCCAGCGCAACTTCCAGGGCTACACCACC
CATGCAGGTACAGAACTTTTTGGCTTTGGTGCGACATCTATTAGTATGCTGCATGATGCTTATGTGCAGAATCACAAGCA
GTTAAAAGAATATTATCAAGCTGTTGCTGGTGATGCTTTACCTGTGAGCAAAGGTATCAAACTCACAACCGATGATATTC
TCAGACGGGATGTGATTATGTGTATCATGTCTAACTTTTATCTGCATAAGCAAGAGATTGAGGAGAAATATCAGATCAAT
TTTGATGAATATTTCTCTCAAGAAATTGCAGCTTTAAAACCATTAGCGGCTGATGGATTAGTTAGTCTCTCTAGCAAACA
CATTCAAGTAACAGAAATCGGTAGATTACTCGTGAGGAATATCGCTGTTGTCTTTGATATTTATCACCACAATCAAGACA
AGCAATTCTCTCGTACTATTTAA

Upstream 100 bases:

>100_bases
TCGATAGGTGTTATTGAATTTTGTAGCCCTTGGGCTTTCCGTAGGGTATTTTGACTTCCACGTAGCGGCATGGTGTGGTT
GCAGTACCTTGGAGGTTTTG

Downstream 100 bases:

>100_bases
TTCACAGGGGTGCGGGGCTGAGGTATGGGAGAAAAATTTACCTAGTCTCCAATCCTCAGTTTTTTATAGTCCCCTGATTG
GCGCTAGTTTCTGGCTTGAT

Product: coproporphyrinogen III oxidase

Products: NA

Alternate protein names: Coprogen oxidase; Coproporphyrinogenase [H]

Number of amino acids: Translated: 460; Mature: 460

Protein sequence:

>460_residues
MVFVLPGVKFDLDMIKKYDTPAPRYTSYPPATQLTEEFSATDYQSAIAASNHRKSPISLYFHIPFCQSSCYFCGCNTVIS
NNKNIAKPYLEHLVKEIKHTSNLIDPDRKVLQVHWGGGTPNYLDCDQVEFLWKHIHRHFNIDPQAEISIEINPRYVDQNY
ISFLREIGFNRISFGIQDFNSQVQKAVNRIQPEELLVNVMSWIKAAKFDSVNVDLIYGLPHQTLQTFRETVKKTVALDPD
RIVVFNFAYVPWLKPAQKNIPLEALPQPQEKLEILKMTIEELTNSQYLFIGMDHFAKHNDELAIAQRNHTLQRNFQGYTT
HAGTELFGFGATSISMLHDAYVQNHKQLKEYYQAVAGDALPVSKGIKLTTDDILRRDVIMCIMSNFYLHKQEIEEKYQIN
FDEYFSQEIAALKPLAADGLVSLSSKHIQVTEIGRLLVRNIAVVFDIYHHNQDKQFSRTI

Sequences:

>Translated_460_residues
MVFVLPGVKFDLDMIKKYDTPAPRYTSYPPATQLTEEFSATDYQSAIAASNHRKSPISLYFHIPFCQSSCYFCGCNTVIS
NNKNIAKPYLEHLVKEIKHTSNLIDPDRKVLQVHWGGGTPNYLDCDQVEFLWKHIHRHFNIDPQAEISIEINPRYVDQNY
ISFLREIGFNRISFGIQDFNSQVQKAVNRIQPEELLVNVMSWIKAAKFDSVNVDLIYGLPHQTLQTFRETVKKTVALDPD
RIVVFNFAYVPWLKPAQKNIPLEALPQPQEKLEILKMTIEELTNSQYLFIGMDHFAKHNDELAIAQRNHTLQRNFQGYTT
HAGTELFGFGATSISMLHDAYVQNHKQLKEYYQAVAGDALPVSKGIKLTTDDILRRDVIMCIMSNFYLHKQEIEEKYQIN
FDEYFSQEIAALKPLAADGLVSLSSKHIQVTEIGRLLVRNIAVVFDIYHHNQDKQFSRTI
>Mature_460_residues
MVFVLPGVKFDLDMIKKYDTPAPRYTSYPPATQLTEEFSATDYQSAIAASNHRKSPISLYFHIPFCQSSCYFCGCNTVIS
NNKNIAKPYLEHLVKEIKHTSNLIDPDRKVLQVHWGGGTPNYLDCDQVEFLWKHIHRHFNIDPQAEISIEINPRYVDQNY
ISFLREIGFNRISFGIQDFNSQVQKAVNRIQPEELLVNVMSWIKAAKFDSVNVDLIYGLPHQTLQTFRETVKKTVALDPD
RIVVFNFAYVPWLKPAQKNIPLEALPQPQEKLEILKMTIEELTNSQYLFIGMDHFAKHNDELAIAQRNHTLQRNFQGYTT
HAGTELFGFGATSISMLHDAYVQNHKQLKEYYQAVAGDALPVSKGIKLTTDDILRRDVIMCIMSNFYLHKQEIEEKYQIN
FDEYFSQEIAALKPLAADGLVSLSSKHIQVTEIGRLLVRNIAVVFDIYHHNQDKQFSRTI

Specific function: Anaerobic transformation of coproporphyrinogen-III into protoporphyrinogen-IX [H]

COG id: COG0635

COG function: function code H; Coproporphyrinogen III oxidase and related Fe-S oxidoreductases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anaerobic coproporphyrinogen-III oxidase family [H]

Homologues:

Organism=Escherichia coli, GI87082341, Length=455, Percent_Identity=47.4725274725275, Blast_Score=441, Evalue=1e-125,
Organism=Escherichia coli, GI1789325, Length=196, Percent_Identity=27.0408163265306, Blast_Score=98, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR004558
- InterPro:   IPR010723
- InterPro:   IPR007197 [H]

Pfam domain/function: PF06969 HemN_C; PF04055 Radical_SAM [H]

EC number: =1.3.99.22 [H]

Molecular weight: Translated: 53024; Mature: 53024

Theoretical pI: Translated: 6.93; Mature: 6.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVFVLPGVKFDLDMIKKYDTPAPRYTSYPPATQLTEEFSATDYQSAIAASNHRKSPISLY
CEEEECCCCCCHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHCCCCCCCEEEE
FHIPFCQSSCYFCGCNTVISNNKNIAKPYLEHLVKEIKHTSNLIDPDRKVLQVHWGGGTP
EEEEECCCCCEEEECCCEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCC
NYLDCDQVEFLWKHIHRHFNIDPQAEISIEINPRYVDQNYISFLREIGFNRISFGIQDFN
CCCCCHHHHHHHHHHHHHCCCCCCCEEEEEECCEECCHHHHHHHHHHCCCHHHHHHHHHH
SQVQKAVNRIQPEELLVNVMSWIKAAKFDSVNVDLIYGLPHQTLQTFRETVKKTVALDPD
HHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCC
RIVVFNFAYVPWLKPAQKNIPLEALPQPQEKLEILKMTIEELTNSQYLFIGMDHFAKHND
CEEEEEEEECCCCCCHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECHHHHCCCC
ELAIAQRNHTLQRNFQGYTTHAGTELFGFGATSISMLHDAYVQNHKQLKEYYQAVAGDAL
CEEEEECCCHHHHCCCCCEECCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PVSKGIKLTTDDILRRDVIMCIMSNFYLHKQEIEEKYQINFDEYFSQEIAALKPLAADGL
CCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCH
VSLSSKHIQVTEIGRLLVRNIAVVFDIYHHNQDKQFSRTI
HHHCCCCEEHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCC
>Mature Secondary Structure
MVFVLPGVKFDLDMIKKYDTPAPRYTSYPPATQLTEEFSATDYQSAIAASNHRKSPISLY
CEEEECCCCCCHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHCCCCCCCEEEE
FHIPFCQSSCYFCGCNTVISNNKNIAKPYLEHLVKEIKHTSNLIDPDRKVLQVHWGGGTP
EEEEECCCCCEEEECCCEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCC
NYLDCDQVEFLWKHIHRHFNIDPQAEISIEINPRYVDQNYISFLREIGFNRISFGIQDFN
CCCCCHHHHHHHHHHHHHCCCCCCCEEEEEECCEECCHHHHHHHHHHCCCHHHHHHHHHH
SQVQKAVNRIQPEELLVNVMSWIKAAKFDSVNVDLIYGLPHQTLQTFRETVKKTVALDPD
HHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCC
RIVVFNFAYVPWLKPAQKNIPLEALPQPQEKLEILKMTIEELTNSQYLFIGMDHFAKHND
CEEEEEEEECCCCCCHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECHHHHCCCC
ELAIAQRNHTLQRNFQGYTTHAGTELFGFGATSISMLHDAYVQNHKQLKEYYQAVAGDAL
CEEEEECCCHHHHCCCCCEECCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PVSKGIKLTTDDILRRDVIMCIMSNFYLHKQEIEEKYQINFDEYFSQEIAALKPLAADGL
CCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCH
VSLSSKHIQVTEIGRLLVRNIAVVFDIYHHNQDKQFSRTI
HHHCCCCEEHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]