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The map label for this gene is pimB [H]

Identifier: 75909777

GI number: 75909777

Start: 4450065

End: 4451234

Strand: Direct

Name: pimB [H]

Synonym: Ava_3572

Alternate gene names: 75909777

Gene position: 4450065-4451234 (Clockwise)

Preceding gene: 75909771

Following gene: 75909778

Centisome position: 69.91

GC content: 36.84

Gene sequence:

>1170_bases
GTGGAATATAAAAAAGAAAACTTCAATTTACTACCTGCTTCTATTCTGACCTTAGGTTCTGGTTGGTTTCCTACAAATCC
TGGGGGTTTGGAAAGATATATTTATGAGTTGACTTATCAATTAGCAGCTAATCAAGATAGAGTAGAGTTATGTGGAGTTG
GCTTACCAACTAATGAATTTCATTTGCCAATTAAATTAACTAATTTAGCATCTCCAGATAGTAAAATTTGGCAAAGATTT
TGGTCTATTCGGACTAATTTCCAGAAAACAAGAATAAGCAAACCGGACGCAATCAATTTACATTTTGCTTTATATAGTTT
TCCTATTTTAGATATTTTGCCTCAGGGTGTACCCATTACTTTTAATTTTCATGGGCCTTGGGCATCAGAAAGTAAACAGG
AATTAGTAAAGAATAAAATCAGTATTTTTTTAAAGCGTCGGCTGATAGAACAAACCACATATAATCGTTGCGATCGCTTT
ATTGTTCTGAGTAAAGCATTCGGCAATATATTACACCAACAATATCAAATTCCTTGGCAAAAAATACATATTATTCCTGG
TGGTGTGAACATTGATAAATTTCAGCCAAATTTATCGCGTCAACAAGCTCGCCAGCAGCTAAATTGGCCTGAAAGTCGTC
CTATTTTATTTACATCCAGACGTTTAGTTCACCGTGTGGGAGTAGACAAACTATTACAAGCATTAGCCATCATTAAACCA
AGAGTACCCGATATTTGGCTAGCGATCGCCGGTCGGGGACATCTGCAAGGGACATTGGCAAAACAAGCTCAAGAGTTGGG
TTTAGAGAACAACGTAAAGTTTTTAGGTTTTCTCCCAGATGAGCAGTTACCTATCGCTTACCAAGCTGCTAATTTAACTG
TTATGCCCAGTCAATCTTTTGAAGGTTTTGGGTTAGCAATTACTGAATCTTTGGCTTGTGGTACTCCTGTTTTATGCACT
CCTATTGGAGGTATGCCAGAAATTTTAACTCCATTTTCACCAGAATTAATTACTACATCTGCGGAAGCTACTGCTATTGC
GGAGAAAATAGTACATATATTGCTAGAACAAATACCAACACCTTCACGAGAAGAATGTCGCCAATATGCTGTAACTAACT
TTGATTGGCAGAAAATTGCTCAACAAGTACGGCGAGTTATTTTAGCTTAA

Upstream 100 bases:

>100_bases
CTTCCTGATAATCTTGACAATCTTGCTAAATATATAAACGGAGTGATACTTCATATCGAAGCAAATCTCCTCAAGCTCCA
CACAGTACTAGGAGATAAGA

Downstream 100 bases:

>100_bases
AAAAATTAAGAGAGTAGTTGACTAATGAAAATATTATTTTTAGACCAGAGTGGTAAACCCGGTGGTGCAGAGTTGTGTTT
AATTGATATTGCGAAACCTT

Product: group 1 glycosyl transferase

Products: NA

Alternate protein names: Alpha-D-mannose-alpha-(1-6)-phosphatidylmyo-inositol-mannosyltransferase; Alpha-mannosyltransferase; Alpha-manT; Guanosine diphosphomannose-phosphatidyl-inositol alpha-mannosyltransferase; Phosphatidylinositol alpha-mannosyltransferase; PI alpha-mannosyltransferase [H]

Number of amino acids: Translated: 389; Mature: 389

Protein sequence:

>389_residues
MEYKKENFNLLPASILTLGSGWFPTNPGGLERYIYELTYQLAANQDRVELCGVGLPTNEFHLPIKLTNLASPDSKIWQRF
WSIRTNFQKTRISKPDAINLHFALYSFPILDILPQGVPITFNFHGPWASESKQELVKNKISIFLKRRLIEQTTYNRCDRF
IVLSKAFGNILHQQYQIPWQKIHIIPGGVNIDKFQPNLSRQQARQQLNWPESRPILFTSRRLVHRVGVDKLLQALAIIKP
RVPDIWLAIAGRGHLQGTLAKQAQELGLENNVKFLGFLPDEQLPIAYQAANLTVMPSQSFEGFGLAITESLACGTPVLCT
PIGGMPEILTPFSPELITTSAEATAIAEKIVHILLEQIPTPSREECRQYAVTNFDWQKIAQQVRRVILA

Sequences:

>Translated_389_residues
MEYKKENFNLLPASILTLGSGWFPTNPGGLERYIYELTYQLAANQDRVELCGVGLPTNEFHLPIKLTNLASPDSKIWQRF
WSIRTNFQKTRISKPDAINLHFALYSFPILDILPQGVPITFNFHGPWASESKQELVKNKISIFLKRRLIEQTTYNRCDRF
IVLSKAFGNILHQQYQIPWQKIHIIPGGVNIDKFQPNLSRQQARQQLNWPESRPILFTSRRLVHRVGVDKLLQALAIIKP
RVPDIWLAIAGRGHLQGTLAKQAQELGLENNVKFLGFLPDEQLPIAYQAANLTVMPSQSFEGFGLAITESLACGTPVLCT
PIGGMPEILTPFSPELITTSAEATAIAEKIVHILLEQIPTPSREECRQYAVTNFDWQKIAQQVRRVILA
>Mature_389_residues
MEYKKENFNLLPASILTLGSGWFPTNPGGLERYIYELTYQLAANQDRVELCGVGLPTNEFHLPIKLTNLASPDSKIWQRF
WSIRTNFQKTRISKPDAINLHFALYSFPILDILPQGVPITFNFHGPWASESKQELVKNKISIFLKRRLIEQTTYNRCDRF
IVLSKAFGNILHQQYQIPWQKIHIIPGGVNIDKFQPNLSRQQARQQLNWPESRPILFTSRRLVHRVGVDKLLQALAIIKP
RVPDIWLAIAGRGHLQGTLAKQAQELGLENNVKFLGFLPDEQLPIAYQAANLTVMPSQSFEGFGLAITESLACGTPVLCT
PIGGMPEILTPFSPELITTSAEATAIAEKIVHILLEQIPTPSREECRQYAVTNFDWQKIAQQVRRVILA

Specific function: Catalyzes the addition of a mannose residue from GDP-D- mannose to the position 6 of a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1) to generate phosphatidyl-myo-inositol bearing alpha-1,2- and alpha-1,6-linked mannose resid

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 1 family [H]

Homologues:

Organism=Homo sapiens, GI11863130, Length=391, Percent_Identity=21.4833759590793, Blast_Score=75, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI9755344, Length=381, Percent_Identity=20.997375328084, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001296 [H]

Pfam domain/function: PF00534 Glycos_transf_1 [H]

EC number: =2.4.1.57 [H]

Molecular weight: Translated: 44100; Mature: 44100

Theoretical pI: Translated: 9.48; Mature: 9.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEYKKENFNLLPASILTLGSGWFPTNPGGLERYIYELTYQLAANQDRVELCGVGLPTNEF
CCCCCCCCCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCE
HLPIKLTNLASPDSKIWQRFWSIRTNFQKTRISKPDAINLHFALYSFPILDILPQGVPIT
EEEEEEECCCCCHHHHHHHHHHHHCCHHHHHCCCCCEEEEEEHHHHCCHHHHCCCCCEEE
FNFHGPWASESKQELVKNKISIFLKRRLIEQTTYNRCDRFIVLSKAFGNILHQQYQIPWQ
EEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHCCCCE
KIHIIPGGVNIDKFQPNLSRQQARQQLNWPESRPILFTSRRLVHRVGVDKLLQALAIIKP
EEEEECCCCCCCCCCCCHHHHHHHHHCCCCCCCCEEEHHHHHHHHHCHHHHHHHHHHHCC
RVPDIWLAIAGRGHLQGTLAKQAQELGLENNVKFLGFLPDEQLPIAYQAANLTVMPSQSF
CCCCEEEEECCCCCHHHHHHHHHHHCCCCCCCEEEEECCCCCCCEEEEECCEEEECCCCC
EGFGLAITESLACGTPVLCTPIGGMPEILTPFSPELITTSAEATAIAEKIVHILLEQIPT
CCCCEEEEHHHCCCCCEEECCCCCCCHHCCCCCCCCEECCHHHHHHHHHHHHHHHHHCCC
PSREECRQYAVTNFDWQKIAQQVRRVILA
CCHHHHHHHHCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MEYKKENFNLLPASILTLGSGWFPTNPGGLERYIYELTYQLAANQDRVELCGVGLPTNEF
CCCCCCCCCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCE
HLPIKLTNLASPDSKIWQRFWSIRTNFQKTRISKPDAINLHFALYSFPILDILPQGVPIT
EEEEEEECCCCCHHHHHHHHHHHHCCHHHHHCCCCCEEEEEEHHHHCCHHHHCCCCCEEE
FNFHGPWASESKQELVKNKISIFLKRRLIEQTTYNRCDRFIVLSKAFGNILHQQYQIPWQ
EEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHCCCCE
KIHIIPGGVNIDKFQPNLSRQQARQQLNWPESRPILFTSRRLVHRVGVDKLLQALAIIKP
EEEEECCCCCCCCCCCCHHHHHHHHHCCCCCCCCEEEHHHHHHHHHCHHHHHHHHHHHCC
RVPDIWLAIAGRGHLQGTLAKQAQELGLENNVKFLGFLPDEQLPIAYQAANLTVMPSQSF
CCCCEEEEECCCCCHHHHHHHHHHHCCCCCCCEEEEECCCCCCCEEEEECCEEEECCCCC
EGFGLAITESLACGTPVLCTPIGGMPEILTPFSPELITTSAEATAIAEKIVHILLEQIPT
CCCCEEEEHHHCCCCCEEECCCCCCCHHCCCCCCCCEECCHHHHHHHHHHHHHHHHHCCC
PSREECRQYAVTNFDWQKIAQQVRRVILA
CCHHHHHHHHCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA