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The map label for this gene is hsdM [C]

Identifier: 75909704

GI number: 75909704

Start: 4338039

End: 4340123

Strand: Direct

Name: hsdM [C]

Synonym: Ava_3498

Alternate gene names: 75909704

Gene position: 4338039-4340123 (Clockwise)

Preceding gene: 75909701

Following gene: 75909705

Centisome position: 68.15

GC content: 43.02

Gene sequence:

>2085_bases
TTGACCCCAGAAGAACTAAAACAACTTGAAGCGAACCTTTGGCAAAGTGCTGATACCCTACGGGCAAACTCAGACCTGAA
ATCTAGTGAGTATTCTACGCCCGTGATGGGGTTAATATTTCTCAAGTTTGCTGATAACAAATATCGCCAGTATGCGGCAG
AGATTCAGCAAGAATATGAAGCACTCAAAGGAACTCGCAGAGAAAAGGCGATCGCCGAAATTGCCATTGAGAAGTGTGGG
TTTTATCTGCCAGACCATGCTCGTTATAACTATTTGCTCAACCTACCAGAAGAGGAAGATATCGCCAAGGCTATCAAAGC
GGCGATGGTGTCCATTGAATCATATAAGCCAGAACTTAAGGACACCTTACCCCAAGATGAGTATTTTCGGCTGACGCGCA
CAGACAAAGGTATTCCGAAGCAACTGTTAAAAAACTTCTCGAATATTCCTGAAAATGCTACTGGGGATATGTTCGGGCAG
ATTTATGAGTATTTTCTGGGTAATTTTGCTCTCTCAGAAGGGCAGGGTGGAGGTGAGTTTTTCACACCGCGTTCTGTGGT
GCGGTTGATGGTAGAAATCATTGAACCTCATCAGGGGACTGTGTTTGACCCCGCTTGTGGTTCTGGGGGAATGTTTGTCC
AGTCTGCTCAATTTATTGAAGAACAGCGCAAAAAGTTAAATCAGTCTGCTGCTGACGATCTGTTTGTCTATGGGCAAGAG
AAGACCCTGGAGACGGTGAAGTTGGCAAAAATGAACATTGCAGTCAATGGGTTACGGGGCGATGTGCGTCAGACAAATAC
GTACTATGAAGACCCGTTTGGCAGTTTTGGCAAGTTTGATTATGTCCTAGCTAATCCGCCATTTAATGTGGATGATGTTA
ATCTTAGCCGAGTGGAAATCGATGCTAGATTTAACACCTACGGTATCCCGCGCAATAAGACTAAGGGGAAGAAGCAGGAA
CAGGGTAATGAGACTGTACCTAATGCCAATTATCTTTGGATTAATTTATTTGCTACATCGCTAAAACCCAAGGGTAGGGC
GGCGTTAGTAATGGCTAATTCGGCATCAGATGCGCGTCACTCTGAAGCAGATATTCGCCAAAAGCTAATTGAAGAAAATT
TGATTTATGGGATGCTGACGCTGCCATCAAATATGTTTTATACGGTGACGCTACCTGCAACTCTGTGGTTTTTTGATCGG
GGCAAGACGGATGATAAAATTCTGTTTATTGATGCGCGAAATATTTTTACTCAGGTTGACCGCTCACATCGGGAGTTTTC
CACAGAACAAATTAGTAATATTGCTATTATCAGCCATTTGCGCCGGGGTAGGAGCCATCGGTTTATTGAACTGATTAATA
ATTATTTTCAGCAAGGGATGGTGAAGCTAAGAGAGAATCAAGCACAGGTGCAGCAAGTTTCCCAGCAGTTAATCACTGTG
TTGAATGATGGAATGGATGATATTAAAGCTAGGGAAGCGGCTGTTGATTTTCTCAATTTGTGGGATGATTTGCCAGATTT
AGAAATTCAGTATCAAGGTTATTTAGATAAATATAATTTTCCAGAAATAAATATAGAAATACAAAATCAAGCACAGCAAG
AACTCAGTGCGGCATTTAAACCATTTTTTGATGACATCCATCTGGGATTGAAGCAGCTTGATAAAACTATCCGCGCCCAT
GAAACGGCTTTGGCAGAAAAAGCAAAGGAAGAGGGGAAACGGGGACAGATTGACAAGCAAGTTAAGACTCTCAAAGCCAC
GCTGGAAACGCTGCATACAGATGTAAAATCGGCAGAATCATTTTTTATCCACATTCGCTGGTTACAGGAACGTTTCCCGA
AGGCAGAATATGAGGATGTGACGGGGTTGTGTAAGTTGGCGACTCCCGCAGATGTGAAGGAACAGGATTATTCCCTAAAT
CCTGGGCGGTATGTGGGGGTAGTGATTGAGGAAGATGGGAAGACGGAGGAGGAGTTTATTGAGGAGATTTTAGGGTGGAA
TACAGAGTTAGAAAAGCTGAATCAGGAAGCAATAAAACTAGGAGACGTAATACGTCACAATATTCAGCAGTTAGTAGGGG
AATAA

Upstream 100 bases:

>100_bases
TCAAGTTGTGGATCAGGGGAGTGGCTGTTTTTGTCACAGAACCCAATGCGTGCATATAATTTCATAACAGATAAATTACC
GACCTACAGCATCTAAAGCC

Downstream 100 bases:

>100_bases
CAATTTATGAATTGTATAGAATTGAGTCTTGCTGATACTTGTGAATTTATAAATGGAGGTGCATGGTCTGATAAAGAGTA
TGTAGAAGCCGGAATTCCTG

Product: N-6 DNA methylase

Products: NA

Alternate protein names: M.MjaXP [H]

Number of amino acids: Translated: 694; Mature: 693

Protein sequence:

>694_residues
MTPEELKQLEANLWQSADTLRANSDLKSSEYSTPVMGLIFLKFADNKYRQYAAEIQQEYEALKGTRREKAIAEIAIEKCG
FYLPDHARYNYLLNLPEEEDIAKAIKAAMVSIESYKPELKDTLPQDEYFRLTRTDKGIPKQLLKNFSNIPENATGDMFGQ
IYEYFLGNFALSEGQGGGEFFTPRSVVRLMVEIIEPHQGTVFDPACGSGGMFVQSAQFIEEQRKKLNQSAADDLFVYGQE
KTLETVKLAKMNIAVNGLRGDVRQTNTYYEDPFGSFGKFDYVLANPPFNVDDVNLSRVEIDARFNTYGIPRNKTKGKKQE
QGNETVPNANYLWINLFATSLKPKGRAALVMANSASDARHSEADIRQKLIEENLIYGMLTLPSNMFYTVTLPATLWFFDR
GKTDDKILFIDARNIFTQVDRSHREFSTEQISNIAIISHLRRGRSHRFIELINNYFQQGMVKLRENQAQVQQVSQQLITV
LNDGMDDIKAREAAVDFLNLWDDLPDLEIQYQGYLDKYNFPEINIEIQNQAQQELSAAFKPFFDDIHLGLKQLDKTIRAH
ETALAEKAKEEGKRGQIDKQVKTLKATLETLHTDVKSAESFFIHIRWLQERFPKAEYEDVTGLCKLATPADVKEQDYSLN
PGRYVGVVIEEDGKTEEEFIEEILGWNTELEKLNQEAIKLGDVIRHNIQQLVGE

Sequences:

>Translated_694_residues
MTPEELKQLEANLWQSADTLRANSDLKSSEYSTPVMGLIFLKFADNKYRQYAAEIQQEYEALKGTRREKAIAEIAIEKCG
FYLPDHARYNYLLNLPEEEDIAKAIKAAMVSIESYKPELKDTLPQDEYFRLTRTDKGIPKQLLKNFSNIPENATGDMFGQ
IYEYFLGNFALSEGQGGGEFFTPRSVVRLMVEIIEPHQGTVFDPACGSGGMFVQSAQFIEEQRKKLNQSAADDLFVYGQE
KTLETVKLAKMNIAVNGLRGDVRQTNTYYEDPFGSFGKFDYVLANPPFNVDDVNLSRVEIDARFNTYGIPRNKTKGKKQE
QGNETVPNANYLWINLFATSLKPKGRAALVMANSASDARHSEADIRQKLIEENLIYGMLTLPSNMFYTVTLPATLWFFDR
GKTDDKILFIDARNIFTQVDRSHREFSTEQISNIAIISHLRRGRSHRFIELINNYFQQGMVKLRENQAQVQQVSQQLITV
LNDGMDDIKAREAAVDFLNLWDDLPDLEIQYQGYLDKYNFPEINIEIQNQAQQELSAAFKPFFDDIHLGLKQLDKTIRAH
ETALAEKAKEEGKRGQIDKQVKTLKATLETLHTDVKSAESFFIHIRWLQERFPKAEYEDVTGLCKLATPADVKEQDYSLN
PGRYVGVVIEEDGKTEEEFIEEILGWNTELEKLNQEAIKLGDVIRHNIQQLVGE
>Mature_693_residues
TPEELKQLEANLWQSADTLRANSDLKSSEYSTPVMGLIFLKFADNKYRQYAAEIQQEYEALKGTRREKAIAEIAIEKCGF
YLPDHARYNYLLNLPEEEDIAKAIKAAMVSIESYKPELKDTLPQDEYFRLTRTDKGIPKQLLKNFSNIPENATGDMFGQI
YEYFLGNFALSEGQGGGEFFTPRSVVRLMVEIIEPHQGTVFDPACGSGGMFVQSAQFIEEQRKKLNQSAADDLFVYGQEK
TLETVKLAKMNIAVNGLRGDVRQTNTYYEDPFGSFGKFDYVLANPPFNVDDVNLSRVEIDARFNTYGIPRNKTKGKKQEQ
GNETVPNANYLWINLFATSLKPKGRAALVMANSASDARHSEADIRQKLIEENLIYGMLTLPSNMFYTVTLPATLWFFDRG
KTDDKILFIDARNIFTQVDRSHREFSTEQISNIAIISHLRRGRSHRFIELINNYFQQGMVKLRENQAQVQQVSQQLITVL
NDGMDDIKAREAAVDFLNLWDDLPDLEIQYQGYLDKYNFPEINIEIQNQAQQELSAAFKPFFDDIHLGLKQLDKTIRAHE
TALAEKAKEEGKRGQIDKQVKTLKATLETLHTDVKSAESFFIHIRWLQERFPKAEYEDVTGLCKLATPADVKEQDYSLNP
GRYVGVVIEEDGKTEEEFIEEILGWNTELEKLNQEAIKLGDVIRHNIQQLVGE

Specific function: Methylation of specific adenine residues; required for both restriction and modification activities [H]

COG id: COG0286

COG function: function code V; Type I restriction-modification system methyltransferase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N(4)/N(6)-methyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1790808, Length=416, Percent_Identity=24.0384615384615, Blast_Score=94, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022749
- InterPro:   IPR003356
- InterPro:   IPR002052
- InterPro:   IPR002296 [H]

Pfam domain/function: PF12161 HsdM_N; PF02384 N6_Mtase [H]

EC number: =2.1.1.72 [H]

Molecular weight: Translated: 79397; Mature: 79265

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: PS00092 N6_MTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPEELKQLEANLWQSADTLRANSDLKSSEYSTPVMGLIFLKFADNKYRQYAAEIQQEYE
CCHHHHHHHHHHHHHCHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHH
ALKGTRREKAIAEIAIEKCGFYLPDHARYNYLLNLPEEEDIAKAIKAAMVSIESYKPELK
HHHCCHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHCCCHHH
DTLPQDEYFRLTRTDKGIPKQLLKNFSNIPENATGDMFGQIYEYFLGNFALSEGQGGGEF
HCCCCCHHEEEECCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCEEECCCCCCCCC
FTPRSVVRLMVEIIEPHQGTVFDPACGSGGMFVQSAQFIEEQRKKLNQSAADDLFVYGQE
CCHHHHHHHHHHHHCCCCCCEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEECCC
KTLETVKLAKMNIAVNGLRGDVRQTNTYYEDPFGSFGKFDYVLANPPFNVDDVNLSRVEI
HHHHHHHHHHHEEEEECCCCCHHHCCCCCCCCCCCCCCEEEEEECCCCCCCCCCEEEEEE
DARFNTYGIPRNKTKGKKQEQGNETVPNANYLWINLFATSLKPKGRAALVMANSASDARH
EECCCCCCCCCCCCCCCHHHCCCCCCCCCCEEEEEEEEECCCCCCCEEEEEECCCCCCCC
SEADIRQKLIEENLIYGMLTLPSNMFYTVTLPATLWFFDRGKTDDKILFIDARNIFTQVD
HHHHHHHHHHHHHHHEEEEECCCCCEEEEEECEEEEEEECCCCCCEEEEEEHHHHHHHHH
RSHREFSTEQISNIAIISHLRRGRSHRFIELINNYFQQGMVKLRENQAQVQQVSQQLITV
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LNDGMDDIKAREAAVDFLNLWDDLPDLEIQYQGYLDKYNFPEINIEIQNQAQQELSAAFK
HHCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCEEEEEECCHHHHHHHHHHH
PFFDDIHLGLKQLDKTIRAHETALAEKAKEEGKRGQIDKQVKTLKATLETLHTDVKSAES
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCHH
FFIHIRWLQERFPKAEYEDVTGLCKLATPADVKEQDYSLNPGRYVGVVIEEDGKTEEEFI
HEEHEEEHHHHCCCCCHHHHHHHEECCCCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHH
EEILGWNTELEKLNQEAIKLGDVIRHNIQQLVGE
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TPEELKQLEANLWQSADTLRANSDLKSSEYSTPVMGLIFLKFADNKYRQYAAEIQQEYE
CHHHHHHHHHHHHHCHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHH
ALKGTRREKAIAEIAIEKCGFYLPDHARYNYLLNLPEEEDIAKAIKAAMVSIESYKPELK
HHHCCHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHCCCHHH
DTLPQDEYFRLTRTDKGIPKQLLKNFSNIPENATGDMFGQIYEYFLGNFALSEGQGGGEF
HCCCCCHHEEEECCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCEEECCCCCCCCC
FTPRSVVRLMVEIIEPHQGTVFDPACGSGGMFVQSAQFIEEQRKKLNQSAADDLFVYGQE
CCHHHHHHHHHHHHCCCCCCEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEECCC
KTLETVKLAKMNIAVNGLRGDVRQTNTYYEDPFGSFGKFDYVLANPPFNVDDVNLSRVEI
HHHHHHHHHHHEEEEECCCCCHHHCCCCCCCCCCCCCCEEEEEECCCCCCCCCCEEEEEE
DARFNTYGIPRNKTKGKKQEQGNETVPNANYLWINLFATSLKPKGRAALVMANSASDARH
EECCCCCCCCCCCCCCCHHHCCCCCCCCCCEEEEEEEEECCCCCCCEEEEEECCCCCCCC
SEADIRQKLIEENLIYGMLTLPSNMFYTVTLPATLWFFDRGKTDDKILFIDARNIFTQVD
HHHHHHHHHHHHHHHEEEEECCCCCEEEEEECEEEEEEECCCCCCEEEEEEHHHHHHHHH
RSHREFSTEQISNIAIISHLRRGRSHRFIELINNYFQQGMVKLRENQAQVQQVSQQLITV
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LNDGMDDIKAREAAVDFLNLWDDLPDLEIQYQGYLDKYNFPEINIEIQNQAQQELSAAFK
HHCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCEEEEEECCHHHHHHHHHHH
PFFDDIHLGLKQLDKTIRAHETALAEKAKEEGKRGQIDKQVKTLKATLETLHTDVKSAES
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCHH
FFIHIRWLQERFPKAEYEDVTGLCKLATPADVKEQDYSLNPGRYVGVVIEEDGKTEEEFI
HEEHEEEHHHHCCCCCHHHHHHHEECCCCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHH
EEILGWNTELEKLNQEAIKLGDVIRHNIQQLVGE
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]