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The map label for this gene is rnpA

Identifier: 75909639

GI number: 75909639

Start: 4264992

End: 4265414

Strand: Direct

Name: rnpA

Synonym: Ava_3433

Alternate gene names: 75909639

Gene position: 4264992-4265414 (Clockwise)

Preceding gene: 75909638

Following gene: 75909640

Centisome position: 67.0

GC content: 45.39

Gene sequence:

>423_bases
GTGGCATTGCCCAAAGCAAACCGATTAAAATCCCGGCATGATTTTCAGGCAGTTTTCCGAGAAGGGCTGAGACGAAACAG
CTCTCATTTCACATTGCGAGCATTAAAACCGTCATCTGCCAAAAAGTCTTCTTTGGATACTGCCGCCAAAACCCAACCAG
CAGATGACGTACAAGATATACCTAGTACGCTTATTGGTGTTTCGATTAGTACCAAAGTTAGTAAGAGAGCGGTGGTGCGT
AACCGCATAAAACGGCAAATTACGGCTGCCATGCAGCAATTATTGCCGAGATTAGCACCAGGGTGGAAATTAGTAGTAAT
TGTGAAGCCAACAGCCGCAGAAAGTAAGTGCGGAAGCCAGCAATTTCTGCAAGAATTAGAGCAGTTGTTGGCACAAACTG
AGGTATTACATGGGCATTCGTGA

Upstream 100 bases:

>100_bases
AGAATGCGGACTCCCGATGGCAGAAACGTCATCAGAGCCAGAAGAAAGAGAGGTCGTCATCGTTTGAGCGTGTAGGGTAT
TTTAGGCGCAAAGAATAGCT

Downstream 100 bases:

>100_bases
AGAAGTTTATTATGAAGGCGGCCCCCACATTGGGGATCTAATTTTGAATATACTAGTTGGACTAACTGTTGTAGGTATTC
CCTTAGCAGTTGGAGCAATT

Product: ribonuclease P

Products: NA

Alternate protein names: RNase P protein; RNaseP protein; Protein C5

Number of amino acids: Translated: 140; Mature: 139

Protein sequence:

>140_residues
MALPKANRLKSRHDFQAVFREGLRRNSSHFTLRALKPSSAKKSSLDTAAKTQPADDVQDIPSTLIGVSISTKVSKRAVVR
NRIKRQITAAMQQLLPRLAPGWKLVVIVKPTAAESKCGSQQFLQELEQLLAQTEVLHGHS

Sequences:

>Translated_140_residues
MALPKANRLKSRHDFQAVFREGLRRNSSHFTLRALKPSSAKKSSLDTAAKTQPADDVQDIPSTLIGVSISTKVSKRAVVR
NRIKRQITAAMQQLLPRLAPGWKLVVIVKPTAAESKCGSQQFLQELEQLLAQTEVLHGHS
>Mature_139_residues
ALPKANRLKSRHDFQAVFREGLRRNSSHFTLRALKPSSAKKSSLDTAAKTQPADDVQDIPSTLIGVSISTKVSKRAVVRN
RIKRQITAAMQQLLPRLAPGWKLVVIVKPTAAESKCGSQQFLQELEQLLAQTEVLHGHS

Specific function: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-lead

COG id: COG0594

COG function: function code J; RNase P protein component

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rnpA family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RNPA_ANAVT (Q3M7J6)

Other databases:

- EMBL:   CP000117
- RefSeq:   YP_323935.1
- ProteinModelPortal:   Q3M7J6
- SMR:   Q3M7J6
- STRING:   Q3M7J6
- GeneID:   3679901
- GenomeReviews:   CP000117_GR
- KEGG:   ava:Ava_3433
- NMPDR:   fig|240292.3.peg.3983
- eggNOG:   COG0594
- HOGENOM:   HBG728160
- OMA:   YEHFLRE
- ProtClustDB:   PRK03031
- BioCyc:   AVAR240292:AVA_3433-MONOMER
- HAMAP:   MF_00227
- InterPro:   IPR020568
- InterPro:   IPR014721
- InterPro:   IPR000100
- Gene3D:   G3DSA:3.30.230.10
- ProDom:   PD003629
- TIGRFAMs:   TIGR00188

Pfam domain/function: PF00825 Ribonuclease_P; SSF54211 Ribosomal_S5_D2-typ_fold

EC number: =3.1.26.5

Molecular weight: Translated: 15476; Mature: 15345

Theoretical pI: Translated: 11.50; Mature: 11.50

Prosite motif: PS00648 RIBONUCLEASE_P

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALPKANRLKSRHDFQAVFREGLRRNSSHFTLRALKPSSAKKSSLDTAAKTQPADDVQDI
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHCCCCCHHHHHH
PSTLIGVSISTKVSKRAVVRNRIKRQITAAMQQLLPRLAPGWKLVVIVKPTAAESKCGSQ
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHH
QFLQELEQLLAQTEVLHGHS
HHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
ALPKANRLKSRHDFQAVFREGLRRNSSHFTLRALKPSSAKKSSLDTAAKTQPADDVQDI
CCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHCCCCCHHHHHH
PSTLIGVSISTKVSKRAVVRNRIKRQITAAMQQLLPRLAPGWKLVVIVKPTAAESKCGSQ
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHH
QFLQELEQLLAQTEVLHGHS
HHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA