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The map label for this gene is pyrR

Identifier: 75909335

GI number: 75909335

Start: 3883875

End: 3884417

Strand: Direct

Name: pyrR

Synonym: Ava_3128

Alternate gene names: 75909335

Gene position: 3883875-3884417 (Clockwise)

Preceding gene: 75909334

Following gene: 75909339

Centisome position: 61.01

GC content: 44.38

Gene sequence:

>543_bases
ATGGCTACGCCTGTCAAAGTGGTTGAAATTCTTTCCGCCGAAGACCTCCGCCGTACTTTAACGCGATTGGCATCTCAAAT
TGTTGAAAGAACACGGGATTTATCTCAATTAGTCCTACTAGGTATTTACACTAGGGGCGTGCCACTAGCGGAACTACTAG
CACGTCAAATTGAAACCCTAGAAGGTATTAATGTCGGTGTAGGAGCTTTAGACATTACCTTCTATCGGGACGACCTTGAC
CAAATTGGTTTACGAACGCCAGCTAAAACCAGCATTACGCTCGACTTGACTGGAAAAACAGTTGTTTTGGTAGATGATGT
CATCTTTAAAGGACGGACAATTCGTGCAGCTTTAAATGCCGTTAACGAGTACGGTAGGCCAGAAGTAATTCGTCTAGCGG
TGTTGGTTGACAGGGGTCATAGGGAAGTCCCCATCCATCCAGATTTTGTTGGTAAGCAGTTACCCACAGCGAAAGAAGAA
GTGGTCAAAGTTTATTTACAAGATTGGGATGGCAGAGATGCGGTGGAATTAGTTGGTTATTAA

Upstream 100 bases:

>100_bases
AGCAAAAGGAAAACTTGCTCAAACATTTTCCCCCTTTCCCCCTACCTCAACTCCTAACTTCCCCCACTCCCTATTAACTC
ATTCCCAGGGGTATCGTTCT

Downstream 100 bases:

>100_bases
AGGTAAAAAATAATCCACGAATTGCCAGGTAGTCTACTTTACTTTTTTCTGCCATTTATCTGGAGTTAGACTCATGGGTA
GTAGTTGTGTTTTATGGCTG

Product: bifunctional pyrimidine regulatory protein PyrR uracil phosphoribosyltransferase

Products: NA

Alternate protein names: Pyrimidine operon regulatory protein; Uracil phosphoribosyltransferase; UPRTase

Number of amino acids: Translated: 180; Mature: 179

Protein sequence:

>180_residues
MATPVKVVEILSAEDLRRTLTRLASQIVERTRDLSQLVLLGIYTRGVPLAELLARQIETLEGINVGVGALDITFYRDDLD
QIGLRTPAKTSITLDLTGKTVVLVDDVIFKGRTIRAALNAVNEYGRPEVIRLAVLVDRGHREVPIHPDFVGKQLPTAKEE
VVKVYLQDWDGRDAVELVGY

Sequences:

>Translated_180_residues
MATPVKVVEILSAEDLRRTLTRLASQIVERTRDLSQLVLLGIYTRGVPLAELLARQIETLEGINVGVGALDITFYRDDLD
QIGLRTPAKTSITLDLTGKTVVLVDDVIFKGRTIRAALNAVNEYGRPEVIRLAVLVDRGHREVPIHPDFVGKQLPTAKEE
VVKVYLQDWDGRDAVELVGY
>Mature_179_residues
ATPVKVVEILSAEDLRRTLTRLASQIVERTRDLSQLVLLGIYTRGVPLAELLARQIETLEGINVGVGALDITFYRDDLDQ
IGLRTPAKTSITLDLTGKTVVLVDDVIFKGRTIRAALNAVNEYGRPEVIRLAVLVDRGHREVPIHPDFVGKQLPTAKEEV
VKVYLQDWDGRDAVELVGY

Specific function: Displays also a weak uracil phosphoribosyltransferase activity which is not physiologically significant

COG id: COG2065

COG function: function code F; Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PYRR_ANAVT (Q3M8F0)

Other databases:

- EMBL:   CP000117
- RefSeq:   YP_323631.1
- HSSP:   P65941
- ProteinModelPortal:   Q3M8F0
- SMR:   Q3M8F0
- STRING:   Q3M8F0
- GeneID:   3680796
- GenomeReviews:   CP000117_GR
- KEGG:   ava:Ava_3128
- NMPDR:   fig|240292.3.peg.3138
- eggNOG:   COG2065
- HOGENOM:   HBG641958
- OMA:   ILDITLY
- ProtClustDB:   PRK05205
- BioCyc:   AVAR240292:AVA_3128-MONOMER
- GO:   GO:0006350
- HAMAP:   MF_01219
- InterPro:   IPR000836
- InterPro:   IPR023050

Pfam domain/function: PF00156 Pribosyltran

EC number: =2.4.2.9

Molecular weight: Translated: 19998; Mature: 19867

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: PS00103 PUR_PYR_PR_TRANSFER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATPVKVVEILSAEDLRRTLTRLASQIVERTRDLSQLVLLGIYTRGVPLAELLARQIETL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
EGINVGVGALDITFYRDDLDQIGLRTPAKTSITLDLTGKTVVLVDDVIFKGRTIRAALNA
CCCCCCCCEEEEEEECCCHHHHCCCCCCCCEEEEEECCCEEEEEECHHHCCCHHHHHHHH
VNEYGRPEVIRLAVLVDRGHREVPIHPDFVGKQLPTAKEEVVKVYLQDWDGRDAVELVGY
HHHCCCCHHEEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHCCCC
>Mature Secondary Structure 
ATPVKVVEILSAEDLRRTLTRLASQIVERTRDLSQLVLLGIYTRGVPLAELLARQIETL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
EGINVGVGALDITFYRDDLDQIGLRTPAKTSITLDLTGKTVVLVDDVIFKGRTIRAALNA
CCCCCCCCEEEEEEECCCHHHHCCCCCCCCEEEEEECCCEEEEEECHHHCCCHHHHHHHH
VNEYGRPEVIRLAVLVDRGHREVPIHPDFVGKQLPTAKEEVVKVYLQDWDGRDAVELVGY
HHHCCCCHHEEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA