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The map label for this gene is crtI [H]

Identifier: 75909319

GI number: 75909319

Start: 3866325

End: 3867845

Strand: Direct

Name: crtI [H]

Synonym: Ava_3112

Alternate gene names: 75909319

Gene position: 3866325-3867845 (Clockwise)

Preceding gene: 75909315

Following gene: 75909323

Centisome position: 60.74

GC content: 44.77

Gene sequence:

>1521_bases
ATGTCCGTAACCTCAACTACTTCCCAAAATTCTTTGTTTGATGTCATCGTGATTGGGTCTGGCATTGGCGGACTAGTGAC
AGCAACCCAACTCGCCGCCAAGGGAGCGAAAGTTCTGGTACTAGAAAGCTATATCATTCCTGGTGGGAGTGCTGGCTACT
TTGAGCGTCAAGGCTATCGATTTGACGTTGGGGCTTCCATGATTTTCGGCTTAGGGAACAGAGGGACTACAAACTTACTC
ACCCGTGCTTTACAAGCTGTAAATAGTAGTGTAGAGGCGATCGCTGATCCCGTACAAATCCATTACCACTTACCCAGCAA
CTTAAACCTGAAAGTTGACCGGGTTTATGATAAGTTTTTGCAAAATCTTGCTGCTTACTTTCCTCATGAAACAAAAGGGA
TTCGTCGCTTTTATGACGAATGTTGGCAAGTGTTTAAGTGTCTCAACCGCATGGATTTGTTGTCATTAGAAGAACCTCGG
TATTTGCTGCGAACGTTTTTACAGCATCCTTTAGCGTGTCTAGGTTTACTTAAGTATCTACCTCAAAATGTCGGAGATAT
CGCCCGTCGCTACATCAGAGACCCAGAATTATTGAAATTTATCGATATAGAATGTTACTGCTGGTCTGTAGTGCCAGCAG
CGATGACACCGATGATTAATGCAGGTATGGTCTTTTCTGACAGGCATTATGGCGGTGTTAACTACCCCAAAGGTGGAGTA
GGTCAAATTGCCCAAAAACTTGCAGAGGGCTTAGAAAAAGTCGGTGGTGAGATTCGATATCAAGCCAAAGTAGCAAAAAT
CATTACTGAAAAATACCGTGCTGTCGGTGTACAACTAACTAATGGTGAAATTTATCGAAGCAAACGGATAGTTTCTAATG
CTACACGGTGGGACACATTTGAAAAATTGCTACCTGTAGATAAAATGCCATCTAATGAGAAAGATTGGCAACACAGCTAT
AAAAAATCGCCCAGTTTTCTGAGTTTACACATGGGGGTGAAAGAGTCCGTCTTACCTCAAGGGACAGAATGCCATCACAT
TATCTTGGAAGATTGGCAAAACATGACCCAAGCAGAAGGTACACTGTTTGTCTCCATACCCACATTACTTGATCCAGAAT
TAGCCCCAGAGGGATGCCATATAATTCATGCCTTTACGCCTCATTGGATAAATGATTGGCAAGGGTTTTCTGTGAGTGAC
TACGAAGCGAAGAAAGAAGAGACAGCCTGGCGAATTATTGACCGACTAGAGAAGATTTTTCCTGGTTTAGATGCGGGTTT
AGATTATTTAGAAGTAGGCACACCCCGCACCCATCGCCGCTTTTTAGGACGAGAAGACGGCACTTATGGCCCCATCCCCA
GACGTAAACTGCGGGGGTTATTGTCCATGCCCTTTAATCGCACCGCTATCAAGGGACTGTATTGTGTGGGAGACAGCACA
TTTCCCGGACAGGGTTTAAATGCAGTCGCCTTTTCCGGCTTCGCCTGCGCCCATCGCATCGCCGTAGATTTAGGACTGTG
A

Upstream 100 bases:

>100_bases
TATTTACGATAAATTTGAGGAAATTGCCTAAGCTTTACCTGATTATAGATGTATTATGAAATACGGTTTGGCTGGTTAAT
TCCATGTAAGTGCAGCTTTT

Downstream 100 bases:

>100_bases
AAGGGATGAGAAAGGCGGGAAGAAATACCGCACTGGTTCAGGCTAGGGACTTCCAGATAAAAAAATATTCAAAATGTAGG
ATGTGTCAGTGCGAGAAAAC

Product: FAD dependent oxidoreductase

Products: NA

Alternate protein names: Phytoene desaturase [H]

Number of amino acids: Translated: 506; Mature: 505

Protein sequence:

>506_residues
MSVTSTTSQNSLFDVIVIGSGIGGLVTATQLAAKGAKVLVLESYIIPGGSAGYFERQGYRFDVGASMIFGLGNRGTTNLL
TRALQAVNSSVEAIADPVQIHYHLPSNLNLKVDRVYDKFLQNLAAYFPHETKGIRRFYDECWQVFKCLNRMDLLSLEEPR
YLLRTFLQHPLACLGLLKYLPQNVGDIARRYIRDPELLKFIDIECYCWSVVPAAMTPMINAGMVFSDRHYGGVNYPKGGV
GQIAQKLAEGLEKVGGEIRYQAKVAKIITEKYRAVGVQLTNGEIYRSKRIVSNATRWDTFEKLLPVDKMPSNEKDWQHSY
KKSPSFLSLHMGVKESVLPQGTECHHIILEDWQNMTQAEGTLFVSIPTLLDPELAPEGCHIIHAFTPHWINDWQGFSVSD
YEAKKEETAWRIIDRLEKIFPGLDAGLDYLEVGTPRTHRRFLGREDGTYGPIPRRKLRGLLSMPFNRTAIKGLYCVGDST
FPGQGLNAVAFSGFACAHRIAVDLGL

Sequences:

>Translated_506_residues
MSVTSTTSQNSLFDVIVIGSGIGGLVTATQLAAKGAKVLVLESYIIPGGSAGYFERQGYRFDVGASMIFGLGNRGTTNLL
TRALQAVNSSVEAIADPVQIHYHLPSNLNLKVDRVYDKFLQNLAAYFPHETKGIRRFYDECWQVFKCLNRMDLLSLEEPR
YLLRTFLQHPLACLGLLKYLPQNVGDIARRYIRDPELLKFIDIECYCWSVVPAAMTPMINAGMVFSDRHYGGVNYPKGGV
GQIAQKLAEGLEKVGGEIRYQAKVAKIITEKYRAVGVQLTNGEIYRSKRIVSNATRWDTFEKLLPVDKMPSNEKDWQHSY
KKSPSFLSLHMGVKESVLPQGTECHHIILEDWQNMTQAEGTLFVSIPTLLDPELAPEGCHIIHAFTPHWINDWQGFSVSD
YEAKKEETAWRIIDRLEKIFPGLDAGLDYLEVGTPRTHRRFLGREDGTYGPIPRRKLRGLLSMPFNRTAIKGLYCVGDST
FPGQGLNAVAFSGFACAHRIAVDLGL
>Mature_505_residues
SVTSTTSQNSLFDVIVIGSGIGGLVTATQLAAKGAKVLVLESYIIPGGSAGYFERQGYRFDVGASMIFGLGNRGTTNLLT
RALQAVNSSVEAIADPVQIHYHLPSNLNLKVDRVYDKFLQNLAAYFPHETKGIRRFYDECWQVFKCLNRMDLLSLEEPRY
LLRTFLQHPLACLGLLKYLPQNVGDIARRYIRDPELLKFIDIECYCWSVVPAAMTPMINAGMVFSDRHYGGVNYPKGGVG
QIAQKLAEGLEKVGGEIRYQAKVAKIITEKYRAVGVQLTNGEIYRSKRIVSNATRWDTFEKLLPVDKMPSNEKDWQHSYK
KSPSFLSLHMGVKESVLPQGTECHHIILEDWQNMTQAEGTLFVSIPTLLDPELAPEGCHIIHAFTPHWINDWQGFSVSDY
EAKKEETAWRIIDRLEKIFPGLDAGLDYLEVGTPRTHRRFLGREDGTYGPIPRRKLRGLLSMPFNRTAIKGLYCVGDSTF
PGQGLNAVAFSGFACAHRIAVDLGL

Specific function: This enzyme converts phytoene into lycopene via the intermediaries of phytofluene, zeta-carotene and neurosporene by the introduction of four double bonds [H]

COG id: COG1233

COG function: function code Q; Phytoene dehydrogenase and related proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carotenoid/retinoid oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI229577391, Length=304, Percent_Identity=27.3026315789474, Blast_Score=83, Evalue=6e-16,
Organism=Homo sapiens, GI203098013, Length=484, Percent_Identity=24.3801652892562, Blast_Score=77, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17540238, Length=530, Percent_Identity=23.7735849056604, Blast_Score=82, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002937
- InterPro:   IPR008150
- InterPro:   IPR014105 [H]

Pfam domain/function: PF01593 Amino_oxidase [H]

EC number: NA

Molecular weight: Translated: 56657; Mature: 56526

Theoretical pI: Translated: 8.30; Mature: 8.30

Prosite motif: PS00589 PTS_HPR_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVTSTTSQNSLFDVIVIGSGIGGLVTATQLAAKGAKVLVLESYIIPGGSAGYFERQGYR
CCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHCCCEEEEEEEEECCCCCCCCCCCCCEE
FDVGASMIFGLGNRGTTNLLTRALQAVNSSVEAIADPVQIHYHLPSNLNLKVDRVYDKFL
EECCCHHEEECCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCEEHHHHHHHHH
QNLAAYFPHETKGIRRFYDECWQVFKCLNRMDLLSLEEPRYLLRTFLQHPLACLGLLKYL
HHHHHHCCCCHHHHHHHHHHHHHHHHHHCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
PQNVGDIARRYIRDPELLKFIDIECYCWSVVPAAMTPMINAGMVFSDRHYGGVNYPKGGV
CCCHHHHHHHHCCCCHHHHEEEEEEEEEHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCH
GQIAQKLAEGLEKVGGEIRYQAKVAKIITEKYRAVGVQLTNGEIYRSKRIVSNATRWDTF
HHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHEEEEEECCHHHHHHHHHHCCHHHHHH
EKLLPVDKMPSNEKDWQHSYKKSPSFLSLHMGVKESVLPQGTECHHIILEDWQNMTQAEG
HHHCCCCCCCCCCHHHHHHHHCCCCEEEEECCCHHHHCCCCCCCHHHHHHHHHHHHHCCC
TLFVSIPTLLDPELAPEGCHIIHAFTPHWINDWQGFSVSDYEAKKEETAWRIIDRLEKIF
EEEEEECCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHC
PGLDAGLDYLEVGTPRTHRRFLGREDGTYGPIPRRKLRGLLSMPFNRTAIKGLYCVGDST
CCHHCCCCCEECCCCHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCCHHHCEEEEECCCC
FPGQGLNAVAFSGFACAHRIAVDLGL
CCCCCCCHHHHCCHHHHHHHHHCCCC
>Mature Secondary Structure 
SVTSTTSQNSLFDVIVIGSGIGGLVTATQLAAKGAKVLVLESYIIPGGSAGYFERQGYR
CCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHCCCEEEEEEEEECCCCCCCCCCCCCEE
FDVGASMIFGLGNRGTTNLLTRALQAVNSSVEAIADPVQIHYHLPSNLNLKVDRVYDKFL
EECCCHHEEECCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCEEHHHHHHHHH
QNLAAYFPHETKGIRRFYDECWQVFKCLNRMDLLSLEEPRYLLRTFLQHPLACLGLLKYL
HHHHHHCCCCHHHHHHHHHHHHHHHHHHCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
PQNVGDIARRYIRDPELLKFIDIECYCWSVVPAAMTPMINAGMVFSDRHYGGVNYPKGGV
CCCHHHHHHHHCCCCHHHHEEEEEEEEEHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCH
GQIAQKLAEGLEKVGGEIRYQAKVAKIITEKYRAVGVQLTNGEIYRSKRIVSNATRWDTF
HHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHEEEEEECCHHHHHHHHHHCCHHHHHH
EKLLPVDKMPSNEKDWQHSYKKSPSFLSLHMGVKESVLPQGTECHHIILEDWQNMTQAEG
HHHCCCCCCCCCCHHHHHHHHCCCCEEEEECCCHHHHCCCCCCCHHHHHHHHHHHHHCCC
TLFVSIPTLLDPELAPEGCHIIHAFTPHWINDWQGFSVSDYEAKKEETAWRIIDRLEKIF
EEEEEECCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHC
PGLDAGLDYLEVGTPRTHRRFLGREDGTYGPIPRRKLRGLLSMPFNRTAIKGLYCVGDST
CCHHCCCCCEECCCCHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCCHHHCEEEEECCCC
FPGQGLNAVAFSGFACAHRIAVDLGL
CCCCCCCHHHHCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7592436 [H]