Click here to switch to the map view.

The map label for this gene is ybaL [H]

Identifier: 75909294

GI number: 75909294

Start: 3835753

End: 3838074

Strand: Direct

Name: ybaL [H]

Synonym: Ava_3086

Alternate gene names: 75909294

Gene position: 3835753-3838074 (Clockwise)

Preceding gene: 75909292

Following gene: 75909296

Centisome position: 60.26

GC content: 47.29

Gene sequence:

>2322_bases
GTGCAAGAAGATTTTAGATTAATTGTTGATTTAGTGTCAGTTCTCGCCGTTGCTGCCTGTGGTGGATTGTTTGCGGCGTT
GCTCAAACAACCTGTGCTGCTGGGCTATCTCATCGGCGGGATGGTGGTGGGGCCGGCTGGGCTGGGGCTGATTAAAGAAG
TTATTCAAGTAGAGACTCTGGCACAGTTTGGCGTTGCTTTCTTGTTGTTTGCCTTGGGTGTAGAATTTTCCTTTGCTGAA
TTGAAAAAAGTAAAGGCGATCGCCCTTGGTGGTGGTGGGCTGCAAATTGCCCTGACAATCTTAACTACAGTGCTGGTTTG
TGGGTTAACGGGAGCCTGGGGAGCCTTACCTGCTAAGGGCGTGTTTCTAGGGTCGATTCTCTCCCTATCATCTACAGCCG
TTGTCCTCAAATGCTTGATGGAGCGTAACGAAACGGAAACGCCCCACGGTCAAGTGATGCTGGGGATTTTGGTTGTTCAG
GACTTGGCGCTGGGATTAATGCTGGCGGTGTTACCTGCTTTGCATGAACCAGGGGAAGTCATTGGTATGGCCGTCCTCAC
AGCTTTGGTCAGGATTGGTTTATTTGCGGCTGGGGCGGTGGCGGCTGGGATTTGGGTCATACCGCCTTTATTGCGACTGT
TAGCCCGCACAGAAAGCCGAGAACTATTTTTATTAGGTGTGGTGGCGCTGTGTTTGGGTATTGCCCTACTGACAGAATCT
TTAGGCCTGTCAATTGAAATGGGGGCTTTCGTCGCTGGGTTAATGATATCTGAGGTGGAGTATGCTGACCAAACCCTGAC
CTATGTAGAACCTCTACGAGATATATTTGCTAGTTTATTCTTTGCAGCGATTGGGATGCTCATTGACCCAGTGTTTTTGT
TGCAAAATATAGAACTAATTCTGGGGTTGGTAGCTTTAGTTTTCCTCGGCAAGTTCTTAATTATCACTCCCTTAGTCAAA
CTATTCCGCTACCCATTAAAAACAGCCTTAATTGCTGGCTTGGGATTGGCGCAGATTGGGGAGTTCTCCTTTGTGTTAGC
CAGTGAAGGACAGGCGCTGGGTTTGGTGTCCCGGCGGATATATTTACTGATTCTGGGAACTACAGCCGTTACACTTATGC
TCACTCCATTTGTGTTACGTTTACTACCATCTTTATTTAACTTTGCCGAATCTATACCCTGGCTCAAACCCTACATCTCT
GGAGAAGGTCAAGCATTAGATATTTCAGAAGACCTACCATTTCAAGATCATATAGTGGTGTGCGGTTATGGGCGAGTAGG
TAAGAATTTGGTGAAGTTGTTGCAGCAACACAATGTGCCTGTAGTCGTTATCGACCAATCAGAAAGCCGGATTCAACAGC
TACGAGATGGGGAAATACCTTATGTATACGGTAATTGCGTCAGCCTCCATGTTCTAGAAACAGCAGGAGTTAGTCATGCC
AAAGGTATGGCGATCGCTCTACCTGACCCCATGAGTACCCGTTTGTGTGTGAAACGCGCCCTGGAACTCTGTCCTGAATT
AGATTTGGTGGTTCGCGCTACCCAGGACAAAAACATTGAGTTGCTGTATCAATTGGGGGCGCGGGAAGTGGTGCAACCAG
AGTTTGAAGCCAGTATCGAAATGGCGACTCACTTATTAACCGATGTAGGCTGGACATCAGGTTTATTACAACAAGAAATG
CAGCAAATCCGTAGCGATCATTACTTAGATTTTCGCCCAGAACGGAACGCTGATGAAGTTTCCCGCCACTTACAGCAAGC
TACTCAAGATTTAAATCGCCGTTGGTATGACCTACCAGTCGATTCTCCCCTAATTGGGATGAATTTAGAAGAAGCGGATA
TGCGCTACTTAACAGGTGTAAGCTTAATGGCAATCCGCCGCGCCAACGGTGAAGAAATCGATTATCCCAACAATCAAACC
AAATTAGCAGCAGGCGATCGCTTATTGATTGTCGGCGCTAATGAAGAACTAGCAGCATTAGAGGAATTTGCCCAAGGTAA
GGTAGCTGTTCCCGGACAAAACAGCGCCTGTCAGTGGGTCGCCGTCGATGGTAACTCTGCCGTTTTGGGTAAAACCCTCA
AGGATTTGCCACTGGATTTACAAAGCGGTATCAAAGTACAAGCGATGCGACGAGACGGTAAATTTATTCGCTCTCCCCAT
GACAACATTGATCTGCGGACTGGCGACCAAGTTCTACTATGCGGTAGCCTCTCAAGTCTGAATCAAATACAGCCTCTATT
TGCCGTAGTTAGCGAAATACCTCTAGCGATTCCCCTAGTAAAAGCCAAGGAAACGGAAGTAGTGAAAGAAATGCGGGGAT
GA

Upstream 100 bases:

>100_bases
AATACATAAATTTTGTTGTTTTGGTACAGTTCCCTTCCCCCAGATAGTTAAAAATTTGTATTCTAAAGTTAATAGGTCTT
AATGGTTCTTAGAAAAACTG

Downstream 100 bases:

>100_bases
AGAGGTACGAGGAAAAACTTAGAGAAAGATTTCTCTTGTTTCCTAATCCCCAGTCCCCAATCCCTAGCCTTTGGGTTGTA
AATAGGCGATCGCTTGTTTC

Product: sodium/hydrogen exchanger

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 773; Mature: 773

Protein sequence:

>773_residues
MQEDFRLIVDLVSVLAVAACGGLFAALLKQPVLLGYLIGGMVVGPAGLGLIKEVIQVETLAQFGVAFLLFALGVEFSFAE
LKKVKAIALGGGGLQIALTILTTVLVCGLTGAWGALPAKGVFLGSILSLSSTAVVLKCLMERNETETPHGQVMLGILVVQ
DLALGLMLAVLPALHEPGEVIGMAVLTALVRIGLFAAGAVAAGIWVIPPLLRLLARTESRELFLLGVVALCLGIALLTES
LGLSIEMGAFVAGLMISEVEYADQTLTYVEPLRDIFASLFFAAIGMLIDPVFLLQNIELILGLVALVFLGKFLIITPLVK
LFRYPLKTALIAGLGLAQIGEFSFVLASEGQALGLVSRRIYLLILGTTAVTLMLTPFVLRLLPSLFNFAESIPWLKPYIS
GEGQALDISEDLPFQDHIVVCGYGRVGKNLVKLLQQHNVPVVVIDQSESRIQQLRDGEIPYVYGNCVSLHVLETAGVSHA
KGMAIALPDPMSTRLCVKRALELCPELDLVVRATQDKNIELLYQLGAREVVQPEFEASIEMATHLLTDVGWTSGLLQQEM
QQIRSDHYLDFRPERNADEVSRHLQQATQDLNRRWYDLPVDSPLIGMNLEEADMRYLTGVSLMAIRRANGEEIDYPNNQT
KLAAGDRLLIVGANEELAALEEFAQGKVAVPGQNSACQWVAVDGNSAVLGKTLKDLPLDLQSGIKVQAMRRDGKFIRSPH
DNIDLRTGDQVLLCGSLSSLNQIQPLFAVVSEIPLAIPLVKAKETEVVKEMRG

Sequences:

>Translated_773_residues
MQEDFRLIVDLVSVLAVAACGGLFAALLKQPVLLGYLIGGMVVGPAGLGLIKEVIQVETLAQFGVAFLLFALGVEFSFAE
LKKVKAIALGGGGLQIALTILTTVLVCGLTGAWGALPAKGVFLGSILSLSSTAVVLKCLMERNETETPHGQVMLGILVVQ
DLALGLMLAVLPALHEPGEVIGMAVLTALVRIGLFAAGAVAAGIWVIPPLLRLLARTESRELFLLGVVALCLGIALLTES
LGLSIEMGAFVAGLMISEVEYADQTLTYVEPLRDIFASLFFAAIGMLIDPVFLLQNIELILGLVALVFLGKFLIITPLVK
LFRYPLKTALIAGLGLAQIGEFSFVLASEGQALGLVSRRIYLLILGTTAVTLMLTPFVLRLLPSLFNFAESIPWLKPYIS
GEGQALDISEDLPFQDHIVVCGYGRVGKNLVKLLQQHNVPVVVIDQSESRIQQLRDGEIPYVYGNCVSLHVLETAGVSHA
KGMAIALPDPMSTRLCVKRALELCPELDLVVRATQDKNIELLYQLGAREVVQPEFEASIEMATHLLTDVGWTSGLLQQEM
QQIRSDHYLDFRPERNADEVSRHLQQATQDLNRRWYDLPVDSPLIGMNLEEADMRYLTGVSLMAIRRANGEEIDYPNNQT
KLAAGDRLLIVGANEELAALEEFAQGKVAVPGQNSACQWVAVDGNSAVLGKTLKDLPLDLQSGIKVQAMRRDGKFIRSPH
DNIDLRTGDQVLLCGSLSSLNQIQPLFAVVSEIPLAIPLVKAKETEVVKEMRG
>Mature_773_residues
MQEDFRLIVDLVSVLAVAACGGLFAALLKQPVLLGYLIGGMVVGPAGLGLIKEVIQVETLAQFGVAFLLFALGVEFSFAE
LKKVKAIALGGGGLQIALTILTTVLVCGLTGAWGALPAKGVFLGSILSLSSTAVVLKCLMERNETETPHGQVMLGILVVQ
DLALGLMLAVLPALHEPGEVIGMAVLTALVRIGLFAAGAVAAGIWVIPPLLRLLARTESRELFLLGVVALCLGIALLTES
LGLSIEMGAFVAGLMISEVEYADQTLTYVEPLRDIFASLFFAAIGMLIDPVFLLQNIELILGLVALVFLGKFLIITPLVK
LFRYPLKTALIAGLGLAQIGEFSFVLASEGQALGLVSRRIYLLILGTTAVTLMLTPFVLRLLPSLFNFAESIPWLKPYIS
GEGQALDISEDLPFQDHIVVCGYGRVGKNLVKLLQQHNVPVVVIDQSESRIQQLRDGEIPYVYGNCVSLHVLETAGVSHA
KGMAIALPDPMSTRLCVKRALELCPELDLVVRATQDKNIELLYQLGAREVVQPEFEASIEMATHLLTDVGWTSGLLQQEM
QQIRSDHYLDFRPERNADEVSRHLQQATQDLNRRWYDLPVDSPLIGMNLEEADMRYLTGVSLMAIRRANGEEIDYPNNQT
KLAAGDRLLIVGANEELAALEEFAQGKVAVPGQNSACQWVAVDGNSAVLGKTLKDLPLDLQSGIKVQAMRRDGKFIRSPH
DNIDLRTGDQVLLCGSLSSLNQIQPLFAVVSEIPLAIPLVKAKETEVVKEMRG

Specific function: Unknown

COG id: COG0475

COG function: function code P; Kef-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RCK N-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI157388921, Length=402, Percent_Identity=35.8208955223881, Blast_Score=194, Evalue=2e-49,
Organism=Escherichia coli, GI1786685, Length=552, Percent_Identity=33.3333333333333, Blast_Score=241, Evalue=1e-64,
Organism=Escherichia coli, GI1789749, Length=572, Percent_Identity=27.0979020979021, Blast_Score=189, Evalue=8e-49,
Organism=Escherichia coli, GI1786232, Length=525, Percent_Identity=29.3333333333333, Blast_Score=187, Evalue=2e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006153
- InterPro:   IPR004771
- InterPro:   IPR016040
- InterPro:   IPR003148 [H]

Pfam domain/function: PF00999 Na_H_Exchanger; PF02254 TrkA_N [H]

EC number: NA

Molecular weight: Translated: 83568; Mature: 83568

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQEDFRLIVDLVSVLAVAACGGLFAALLKQPVLLGYLIGGMVVGPAGLGLIKEVIQVETL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
AQFGVAFLLFALGVEFSFAELKKVKAIALGGGGLQIALTILTTVLVCGLTGAWGALPAKG
HHHHHHHHHHHHCCCCCHHHHHHHHEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCCH
VFLGSILSLSSTAVVLKCLMERNETETPHGQVMLGILVVQDLALGLMLAVLPALHEPGEV
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
IGMAVLTALVRIGLFAAGAVAAGIWVIPPLLRLLARTESRELFLLGVVALCLGIALLTES
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
LGLSIEMGAFVAGLMISEVEYADQTLTYVEPLRDIFASLFFAAIGMLIDPVFLLQNIELI
HCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGLVALVFLGKFLIITPLVKLFRYPLKTALIAGLGLAQIGEFSFVLASEGQALGLVSRRI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCEEEEEECCCCCHHHHHHEE
YLLILGTTAVTLMLTPFVLRLLPSLFNFAESIPWLKPYISGEGQALDISEDLPFQDHIVV
EEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCEEECCCCCCCCCCEEE
CGYGRVGKNLVKLLQQHNVPVVVIDQSESRIQQLRDGEIPYVYGNCVSLHVLETAGVSHA
EECCHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHCCCCCEEECCEEEEEEEHHCCCCCC
KGMAIALPDPMSTRLCVKRALELCPELDLVVRATQDKNIELLYQLGAREVVQPEFEASIE
CCEEEECCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHCCCHHHCCCHHHHHHH
MATHLLTDVGWTSGLLQQEMQQIRSDHYLDFRPERNADEVSRHLQQATQDLNRRWYDLPV
HHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEECCCC
DSPLIGMNLEEADMRYLTGVSLMAIRRANGEEIDYPNNQTKLAAGDRLLIVGANEELAAL
CCCEECCCCCHHHHHHHHCHHHHHHCCCCCCCCCCCCCCCEEECCCEEEEEECCHHHHHH
EEFAQGKVAVPGQNSACQWVAVDGNSAVLGKTLKDLPLDLQSGIKVQAMRRDGKFIRSPH
HHHHCCCEECCCCCCCEEEEEECCCCHHHHHHHHHCCCCHHCCCEEEEECCCCCCCCCCC
DNIDLRTGDQVLLCGSLSSLNQIQPLFAVVSEIPLAIPLVKAKETEVVKEMRG
CCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHCC
>Mature Secondary Structure
MQEDFRLIVDLVSVLAVAACGGLFAALLKQPVLLGYLIGGMVVGPAGLGLIKEVIQVETL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
AQFGVAFLLFALGVEFSFAELKKVKAIALGGGGLQIALTILTTVLVCGLTGAWGALPAKG
HHHHHHHHHHHHCCCCCHHHHHHHHEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCCH
VFLGSILSLSSTAVVLKCLMERNETETPHGQVMLGILVVQDLALGLMLAVLPALHEPGEV
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
IGMAVLTALVRIGLFAAGAVAAGIWVIPPLLRLLARTESRELFLLGVVALCLGIALLTES
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
LGLSIEMGAFVAGLMISEVEYADQTLTYVEPLRDIFASLFFAAIGMLIDPVFLLQNIELI
HCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGLVALVFLGKFLIITPLVKLFRYPLKTALIAGLGLAQIGEFSFVLASEGQALGLVSRRI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCEEEEEECCCCCHHHHHHEE
YLLILGTTAVTLMLTPFVLRLLPSLFNFAESIPWLKPYISGEGQALDISEDLPFQDHIVV
EEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCEEECCCCCCCCCCEEE
CGYGRVGKNLVKLLQQHNVPVVVIDQSESRIQQLRDGEIPYVYGNCVSLHVLETAGVSHA
EECCHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHCCCCCEEECCEEEEEEEHHCCCCCC
KGMAIALPDPMSTRLCVKRALELCPELDLVVRATQDKNIELLYQLGAREVVQPEFEASIE
CCEEEECCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHCCCHHHCCCHHHHHHH
MATHLLTDVGWTSGLLQQEMQQIRSDHYLDFRPERNADEVSRHLQQATQDLNRRWYDLPV
HHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEECCCC
DSPLIGMNLEEADMRYLTGVSLMAIRRANGEEIDYPNNQTKLAAGDRLLIVGANEELAAL
CCCEECCCCCHHHHHHHHCHHHHHHCCCCCCCCCCCCCCCEEECCCEEEEEECCHHHHHH
EEFAQGKVAVPGQNSACQWVAVDGNSAVLGKTLKDLPLDLQSGIKVQAMRRDGKFIRSPH
HHHHCCCEECCCCCCCEEEEEECCCCHHHHHHHHHCCCCHHCCCEEEEECCCCCCCCCCC
DNIDLRTGDQVLLCGSLSSLNQIQPLFAVVSEIPLAIPLVKAKETEVVKEMRG
CCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503; 7721718 [H]